1.Study on the Equity of Chinese Health System Performance
Qiang YAO ; Ling XU ; Yaoguang ZHANG
Chinese Health Economics 2017;36(5):79-81
Objective:To Study the equity of Chinese health systems performance and provide evidence for strengthening health system.Methods:Based on WHO health systems performance evaluation framework,the provincial data of expanded pilots under the national health service investigation and relative concentration index (RCI) were used to study the inequality of Chinese health systems performance from regions,income and education,etc.Results:The RCI values were lower than 0.1 on health status and satisfaction dimensions.The RCI of financial risks protection was higher than 0.2,which was at a respective higher level.Conclusion:The health performance of people with lower education and wealth were fragility and these people usually with health shocks.Therefore,the national and regional government should pay more attention on vulnerable group and provide more healthcare management and security support.
2.Preparation of monoclonal antibody against human lung cancer and purification of its antigen by the immunoaffinity chromatography
Xiaoling YAO ; Xiaoyan LIU ; Qiang WU ; Zhenshan XU ; Lihua SONG
Chinese Journal of Immunology 1999;0(12):-
Objective:To produce the mcAb specifically reacting with lung cancer and to purificate its antigen.Methods:The mice were immunized with A549, the mcAb 2B9 was screened by indirect cell ELISA and immunohistochemistry, and its antigen was purificated by immunoaffinity chromatography.Results:A mcAb was obtained, which could react to lung cancer but very little or not to normal lung tissue and other caner tissues, and the antigen of the mcAb was purificated from the cell lysate.Conclusion:A mcAb which can react to lung cancer have been obtained and its antigen was purificated, they may be useful on clinic for diagnosis and prognosis of lung cancer.
3.Combination of arterial perfusion chemotherapy and embolization for the treatment of giant carcinoma of kidney in 21 cases
Qiang DONG ; Danfeng XU ; Weihua DONG ; Yacheng YAO
Journal of Interventional Radiology 2006;0(07):-
Objective To explore the efficiency of arterial perfusion chemotherapy combined with embolization for the treatment of giant carcinoma of the kidney. Methods Arterial perfusion chemotherapy combined with embolization was performed through the renal artery in 21 cases of giant carcinoma of the kidney from April 1992 to April 2006. The chemotherapeutic agents contained carboplatin(300 mg), mitomycin(20 mg) and cyclophosphamide(800 mg). The embolization was conducted with anhydrous alcohol, sodium morrhuate, and lipiodol plus gelatin sponge. Results The arterial perfusion with embolization was successfully obtained in all 21 cases. Surgical resection was accomplished in 15 cases, 1 - 8 weeks after the embolization; revealing severely less or no blood supply to the tumor. Pathological findings showed marked necrosis of tumor cells with peripheral inflammatory infiltration, fibrous proliferation as well as capillary embolization. The survival rates at 1-, 2-, and 3-, year were 80%(12/15), 53.33%(8/15) and 40%(6/15) respectively. Conclusions Combination of perfusion chemotherapy and embolization through the renal artery for the treatment of giant carcinoma of the kidney offers promising clinical effects.
4.Study on the performance evaluation index system for China′s health system
Zhiyong LIU ; Lan YAO ; Ling XU ; Yaoguang ZHANG ; Lei HE ; Min CAI ; Qiang YAO
Chinese Journal of Hospital Administration 2016;32(5):339-342
Objective To construct the performance evaluation framework for China′s health system,and provide evidences for enhancement of such evaluation and the health system.Methods Literature review and empirical research were combined with expert consultation to construct such an evaluation index system.Results In view of both international experiences and China′s specifics,an evaluation index system is built based on the generalized concept model of the health system,consisting of 4 class-1 indicators, 1 5 class-2 indicators and 6 9 class-3 indicators.Conclusions The generalized framework of health system performance evaluation fits such evaluation in China,and indicator optimization and understanding of the shortcomings with cautious explanation are of critical importance.This evaluation remains in its infancy in China,and there is a long way to go before a health system performance evaluation system can be built in China.
5.Research on ursolic acid production of Eriobotrya japonica cell suspension culture in WAVE bioreactor.
Hui-hua LI ; De-heng YAO ; Jian XU ; Wei WANG ; Qiang CHANG ; Ming-hua SU
China Journal of Chinese Materia Medica 2015;40(9):1693-1698
Through scale-up cultivation of Eriobotrya japonica suspension cells using WAVE bioreactor, the cell growth and ursolic acid (UA) accumulation were studied. The comparison test was carried out in the flask and the reactor with cell dry weight (DW) and UA content as evaluation indexes. The culture medium, DW and UA content were compared in 1 L and 5 L working volumes of bioreactor. The orthogonal test with main actors of inoculation amount, speed and angle of rotation was developed to find the optimal combination, in 1 L working volume of bioreactor. DW of the cell growth and the UA content in bioreactor were higher than those of the shaker by 105.5% and 27.65% respectively. In bioreactor, the dynamic changes of elements in the fluid culture, the dry weight of the cell growth and the UA content in 1 L and 5 L working volumes were similar. Inoculation of 80 g, rotational speed of 26 r · min(-1), and angle of 6 ° was the optimal combination, and the cell biomass of 19.01 g · L(-1) and the UA content of 27.750 mg · g(-1) were achieved after 100 h cultivation in 1 L working volume of bioreactor. WAVE Bioreactor is more suitable than flasks for the E. japonica cell suspension culture, and culture parameters can be achieved from 1 L to 5 L amplification.
Biomass
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Bioreactors
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Cell Culture Techniques
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instrumentation
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methods
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Culture Media
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chemistry
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metabolism
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Eriobotrya
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chemistry
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growth & development
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metabolism
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Triterpenes
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analysis
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metabolism
6.Advances in research of assessment framework for national health information system and their enlightenments
Wenxue JI ; Zhiyong LIU ; Qiang YAO ; Ling XU ; Jun WANG ; Chengcheng YIN
Chinese Journal of Medical Library and Information Science 2014;(9):7-11
A national health information system that can provide timely and reliable information plays a very im-portant role in improving public health and health system .However , the system must be assessed at first if it is to be strengthened .The assessment frameworks for the main health information systems in the world were summarized by defining the connotations of national health information system.The advances in assessment of health information systems in China were described with certain suggestions put forward for the research and development of assessment framework for national health information system .
7.UML-based evaluation framework system for National Health Information System
Wenxue JI ; Zhiyong LIU ; Junjian FENG ; Qiang YAO ; Ling XU ; Jun WANG ; Ying YANG
Chinese Journal of Medical Library and Information Science 2015;(9):1-7
National Health Information System is mainly used to support decision-making and to improve the current national health situation.Its importance to display the current national health situation and its problems in developing countries were analyzed with the need to construct its effective evaluation framework system pointed out.Construc-tion of UML-based evaluation framework system for National Health Information System was proposed in order to support decision-making and to provide evidence for the health policy makers by comparing the evaluation frame-work systems for National Health Information System in developing countries .
8.Analysis of endemic changes of schistosomiasis in China from 2002 to 2010
Qiang WANG ; Jing XU ; Lijuan ZHANG ; Hao ZHENG ; Yao RUAN ; Yuwan HAO ; Shizhu LI ; Xiaonong ZHOU
Chinese Journal of Schistosomiasis Control 2015;(3):229-234,250
Objective To provide the reference for schistosomiasis control through analyzing the changes of endemic status of schistosomiasis in China in recent years. Methods The annual data of schistosomiasis prevention and control from 2002 to 2012 were collected, and the descriptive analysis was conducted to describe the changes of schistosomiasis endemic status. Re?sults Sichuan, Yunan and Jiangxi provinces reached the criteria of transmission controlled from 2002 to 2010 while Hubei, Hu?nan, Jiangxi and Anhui provinces reached the criteria of infection controlled in 2008. The number of counties where the trans?mission of schistosomiasis was controlled decreased from 110 in 2002 to 80 in 2010. The numbers of estimated schistosomiasis cases and reported acute cases fell from 810.4 thousands and 913 in 2002 to 325.8 thousands and 43 in 2010, respectively, and they were reduced by 59.79%and 95.40%respectively. The number of infected bovine went down from 23 199 in 2002 to 7 173 in 2010, with a fall of 69.03%. However, the Oncomelania hupensis snails breeding areas kept in 3.7 to 3.8 billion m2 and among which, 125 million m2 areas were newly discovered in non?endemic areas during the nine years. In 2010, 90%of schistosomiasis cases, acute cases, infected bovine, and snail breeding areas were concentrated in 5 provinces, especially in the Dongting Lake and Poyang Lake areas and the regions along the Yangtze River. Conclusions The epidemic of schistosomiasis decreased sig?nificantly from 2002 to 2010. The lake regions are the key and tough areas for schistosomiasis prevention and control. To consoli?date the achievements, the surveillance and case management need to be strengthened as the extension of snail breeding areas and acute cases reported from other places becomes common.
9.Clinicopathological features of submucosal tumors in different upper gastrointestinal locations
Zhipeng QI ; Yunshi ZHONG ; Pinghong ZHOU ; Meidong XU ; Qiang SHI ; Shilun CAI ; Liqing YAO
Chinese Journal of Digestive Endoscopy 2016;33(6):362-366
Objective To analyze the clinicopathological characteristics of upper gastrointestinal submucosal tumors ( SMTs ) . Methods Clinicopathological data of 1 743 patients with 1 775 upper gastrointestinal SMTs in our department from January 2008 to December 2012 were retrospectively analyzed. Results The first finding was that in 702 esophagus cases,leiomyoma(92?59%,650/702) was the most common type of esophageal SMTs. Second, in 1 045 gastric cases, there were 405 lesions at gastric fundus, the most common type of SMTs were 249 ( 61?48%) GISTs and 144 ( 35?56%) leiomyoma. In 307 lesions located at body,the most common type of SMTs were 143( 46?58%) GISTs and 90( 29?32%) leiomyoma. In 191 lesions located at antrum, the most common type of SMTs were 83( 43?46%) heterotopia pancreas and 45(23?56%) hamartoma, followed by 28(14?66%) lipoma and 20(10?47%) GISTs. In 142 lesions located at cardia, the most common type of SMTs was 110 ( 77?46%) leiomyoma. Third, in 28 duodenum cases, there were 19 lesions at duodenal bulb, the most common type of SMTs was 10 heterotopia pancreas, 4 Brunner gland adenoma and 3 GISTs. In 9 lesions located at descending duodenum,the most common type of SMTs was 4 lipomyoma, followed by 2 ectopic pancreas,1 GISTs and 2 others. Conclusion Leiomyoma is the most common type of esophageal SMTs. In gastric fundus and body, the most common type of SMTs are GISTs and leiomyoma. In antrum, the most common type of SMTs are heterotopia pancreas and hamartoma, but in cardia, that is leiomyoma.In duodenal bulb, the most common type of SMTs are heterotopia pancreas, Brunner gland adenoma and GISTs,and in descending duodenum, is lipomyoma.
10.Study on neurofeedback system based on electroencephalogram signals.
Xianjie PU ; Tiejun LIU ; Qiang WU ; Rui ZHANG ; Peng XU ; Ke LI ; Yang XIA ; Dezhong YAO
Journal of Biomedical Engineering 2014;31(4):894-898
Neurofeedback, as an alternative treatment method of behavioral medicine, is a technique which translates the electroencephalogram (EEG) signals to styles as sounds or animation to help people understand their own physical status and learn to enhance or suppress certain EEG signals to regulate their own brain functions after several repeated trainings. This paper develops a neurofeedback system on the foundation of brain-computer interface technique. The EEG features are extracted through real-time signal process and then translated to feedback information. Two feedback screens are designed for relaxation training and attention training individually. The veracity and feasibility of the neurofeedback system are validated through system simulation and preliminary experiment.
Brain-Computer Interfaces
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Electroencephalography
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Female
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Humans
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Neurofeedback