1.Study on the Equity of Chinese Health System Performance
Qiang YAO ; Ling XU ; Yaoguang ZHANG
Chinese Health Economics 2017;36(5):79-81
Objective:To Study the equity of Chinese health systems performance and provide evidence for strengthening health system.Methods:Based on WHO health systems performance evaluation framework,the provincial data of expanded pilots under the national health service investigation and relative concentration index (RCI) were used to study the inequality of Chinese health systems performance from regions,income and education,etc.Results:The RCI values were lower than 0.1 on health status and satisfaction dimensions.The RCI of financial risks protection was higher than 0.2,which was at a respective higher level.Conclusion:The health performance of people with lower education and wealth were fragility and these people usually with health shocks.Therefore,the national and regional government should pay more attention on vulnerable group and provide more healthcare management and security support.
2.Preparation of monoclonal antibody against human lung cancer and purification of its antigen by the immunoaffinity chromatography
Xiaoling YAO ; Xiaoyan LIU ; Qiang WU ; Zhenshan XU ; Lihua SONG
Chinese Journal of Immunology 1999;0(12):-
Objective:To produce the mcAb specifically reacting with lung cancer and to purificate its antigen.Methods:The mice were immunized with A549, the mcAb 2B9 was screened by indirect cell ELISA and immunohistochemistry, and its antigen was purificated by immunoaffinity chromatography.Results:A mcAb was obtained, which could react to lung cancer but very little or not to normal lung tissue and other caner tissues, and the antigen of the mcAb was purificated from the cell lysate.Conclusion:A mcAb which can react to lung cancer have been obtained and its antigen was purificated, they may be useful on clinic for diagnosis and prognosis of lung cancer.
3.Combination of arterial perfusion chemotherapy and embolization for the treatment of giant carcinoma of kidney in 21 cases
Qiang DONG ; Danfeng XU ; Weihua DONG ; Yacheng YAO
Journal of Interventional Radiology 2006;0(07):-
Objective To explore the efficiency of arterial perfusion chemotherapy combined with embolization for the treatment of giant carcinoma of the kidney. Methods Arterial perfusion chemotherapy combined with embolization was performed through the renal artery in 21 cases of giant carcinoma of the kidney from April 1992 to April 2006. The chemotherapeutic agents contained carboplatin(300 mg), mitomycin(20 mg) and cyclophosphamide(800 mg). The embolization was conducted with anhydrous alcohol, sodium morrhuate, and lipiodol plus gelatin sponge. Results The arterial perfusion with embolization was successfully obtained in all 21 cases. Surgical resection was accomplished in 15 cases, 1 - 8 weeks after the embolization; revealing severely less or no blood supply to the tumor. Pathological findings showed marked necrosis of tumor cells with peripheral inflammatory infiltration, fibrous proliferation as well as capillary embolization. The survival rates at 1-, 2-, and 3-, year were 80%(12/15), 53.33%(8/15) and 40%(6/15) respectively. Conclusions Combination of perfusion chemotherapy and embolization through the renal artery for the treatment of giant carcinoma of the kidney offers promising clinical effects.
4.Study on the performance evaluation index system for China′s health system
Zhiyong LIU ; Lan YAO ; Ling XU ; Yaoguang ZHANG ; Lei HE ; Min CAI ; Qiang YAO
Chinese Journal of Hospital Administration 2016;32(5):339-342
Objective To construct the performance evaluation framework for China′s health system,and provide evidences for enhancement of such evaluation and the health system.Methods Literature review and empirical research were combined with expert consultation to construct such an evaluation index system.Results In view of both international experiences and China′s specifics,an evaluation index system is built based on the generalized concept model of the health system,consisting of 4 class-1 indicators, 1 5 class-2 indicators and 6 9 class-3 indicators.Conclusions The generalized framework of health system performance evaluation fits such evaluation in China,and indicator optimization and understanding of the shortcomings with cautious explanation are of critical importance.This evaluation remains in its infancy in China,and there is a long way to go before a health system performance evaluation system can be built in China.
5.Study on neurofeedback system based on electroencephalogram signals.
Xianjie PU ; Tiejun LIU ; Qiang WU ; Rui ZHANG ; Peng XU ; Ke LI ; Yang XIA ; Dezhong YAO
Journal of Biomedical Engineering 2014;31(4):894-898
Neurofeedback, as an alternative treatment method of behavioral medicine, is a technique which translates the electroencephalogram (EEG) signals to styles as sounds or animation to help people understand their own physical status and learn to enhance or suppress certain EEG signals to regulate their own brain functions after several repeated trainings. This paper develops a neurofeedback system on the foundation of brain-computer interface technique. The EEG features are extracted through real-time signal process and then translated to feedback information. Two feedback screens are designed for relaxation training and attention training individually. The veracity and feasibility of the neurofeedback system are validated through system simulation and preliminary experiment.
Brain-Computer Interfaces
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Electroencephalography
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Female
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Humans
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Neurofeedback
6.Clinicopathological features of submucosal tumors in different upper gastrointestinal locations
Zhipeng QI ; Yunshi ZHONG ; Pinghong ZHOU ; Meidong XU ; Qiang SHI ; Shilun CAI ; Liqing YAO
Chinese Journal of Digestive Endoscopy 2016;33(6):362-366
Objective To analyze the clinicopathological characteristics of upper gastrointestinal submucosal tumors ( SMTs ) . Methods Clinicopathological data of 1 743 patients with 1 775 upper gastrointestinal SMTs in our department from January 2008 to December 2012 were retrospectively analyzed. Results The first finding was that in 702 esophagus cases,leiomyoma(92?59%,650/702) was the most common type of esophageal SMTs. Second, in 1 045 gastric cases, there were 405 lesions at gastric fundus, the most common type of SMTs were 249 ( 61?48%) GISTs and 144 ( 35?56%) leiomyoma. In 307 lesions located at body,the most common type of SMTs were 143( 46?58%) GISTs and 90( 29?32%) leiomyoma. In 191 lesions located at antrum, the most common type of SMTs were 83( 43?46%) heterotopia pancreas and 45(23?56%) hamartoma, followed by 28(14?66%) lipoma and 20(10?47%) GISTs. In 142 lesions located at cardia, the most common type of SMTs was 110 ( 77?46%) leiomyoma. Third, in 28 duodenum cases, there were 19 lesions at duodenal bulb, the most common type of SMTs was 10 heterotopia pancreas, 4 Brunner gland adenoma and 3 GISTs. In 9 lesions located at descending duodenum,the most common type of SMTs was 4 lipomyoma, followed by 2 ectopic pancreas,1 GISTs and 2 others. Conclusion Leiomyoma is the most common type of esophageal SMTs. In gastric fundus and body, the most common type of SMTs are GISTs and leiomyoma. In antrum, the most common type of SMTs are heterotopia pancreas and hamartoma, but in cardia, that is leiomyoma.In duodenal bulb, the most common type of SMTs are heterotopia pancreas, Brunner gland adenoma and GISTs,and in descending duodenum, is lipomyoma.
7.UML-based evaluation framework system for National Health Information System
Wenxue JI ; Zhiyong LIU ; Junjian FENG ; Qiang YAO ; Ling XU ; Jun WANG ; Ying YANG
Chinese Journal of Medical Library and Information Science 2015;(9):1-7
National Health Information System is mainly used to support decision-making and to improve the current national health situation.Its importance to display the current national health situation and its problems in developing countries were analyzed with the need to construct its effective evaluation framework system pointed out.Construc-tion of UML-based evaluation framework system for National Health Information System was proposed in order to support decision-making and to provide evidence for the health policy makers by comparing the evaluation frame-work systems for National Health Information System in developing countries .
8.The exploration of the standard training program for bronchosocpists
Haidong HUANG ; Jinwei JIA ; Qing WANG ; Qiang LI ; Chong BAI ; Xiaopeng YAO ; Xiaolu XU
Chinese Journal of Medical Education Research 2011;10(10):1272-1274
This article describes the progress of developing the training base and training methods for bronchoscopists at Changhai hospital in recent years,and then discusses the potential issues and solutions that might occure in the course of training,and finally explores the model and methodology to optimize the training program for Chinese bronchosocpists.
9.Peri-operative managements of complications of peroral endoscopic myotomy for esophageal achalasia
Zhong REN ; Yunshi ZHONG ; Pinghong ZHOU ; Meidong XU ; Mingyan CAI ; Liang LI ; Qiang SHI ; Liqing YAO
Chinese Journal of Digestive Endoscopy 2011;28(11):615-618
ObjectiveTo investigate the managements of complications during and after peroral endoscopic myotomy (POEM) for esophageal achalasia (EA).MethodsData of 119 EA patients who underwent POEM from October 2010 to July 2011 were collected.Complications during and after POEM and during follow-up were analyzed.Results Complications during operation included bleeding in 19 patients ( 16.0% ),mucosa rupture in 9 (7.6%),mediastinal and subcutaneous emphysema in 27 (22.7% ) and pneumothorax in 3 (2.5% ).Complications occurred at the night of procedure included pain in 43 (36.1% ) patients and pneumothorax in 7 ( 5.9% ).Postoperative complications included asymptomatic pneumothorax in 23 patients (19.3%),delayed hemorrhage in 1(0.8%),pleural effusion in 58 (48.7% ),minor pulmonary inflammation or segmental atelectasis in 59 (49.6%),emphysema of mediasti-na and subcutaneous tissue in 76 (63.9% ),and gas under diaphragm or aeroperitoneum in 47 (39.5% ).Complications during follow-up included one case of dysphagia caused by stricture of mucosa and one case of dehiscence at the tunnel entry with food retention.No POEM-correlated death occurred.All the complications were cured by conservative treatments.No additional surgery was needed.ConclusionMain complications as emphysema of mediastina and subcutaneous tissue,pneumothorax,aeroperitoneum and bleeding during and after POEM can be treated timely and effectively with conservative treatment.
10.Computer-aided detection of nodule in low-dose CT screening for lung cancer
Wei TANG ; Jianwei WANG ; Ning WU ; Yao HUANG ; Qiang CAI ; Shijun ZHAO ; Xiaojuan XU
Chinese Journal of Radiology 2012;46(7):619-623
ObjectiveTo evaluate the performance of computer-aided detection (CAD) system for detection of pulmonary nodules in 64-slice low-dose CT screening and to investigate whether CAD can improve the performance of radiologists in detecting pulmonary nodules.MethodsOne hundred low-dose screening CT examinations were randomly selected from the database containing 578 consecutive cases between Jun 2007 and Jun 2008.All the examinations were performed on a 64-MSCT scanner with the exposure of 120 kVp,30 or 40 mA,or automatic exposure control.Before the study started,the screening reports had been made with double reading by two radiologists.All the selected images were analyzed with the lung VCAR software from GE Healthcare with a nodule diameter threshold 3.0 mm.All discrepancies between the screening reports and the CAD results were reviewed and the true non-calcified nodules were determined in consensus by two experienced chest radiologists.Detected nodules were classified by density,size and location.The performance of the double reading and the CAD system were compared and analyzed statistically.McNemar-Bowker test was used for the statistical analysis.ResultsA total of 257 true noncalcified nodules were determined in all 100 low-dose screening CT examinations.The detection rate of CAD system was 91.1% (234/257),with the missed rate of 8.9% (23/257).Twenty three nodules were missed by CAD,in which 10 were solid with the diameter ranged from 2.4 to 6.0 mm,and 13 were nonsolid with the diameter ranged from 2.1 to 8.6 mm.Of the 23 nodules,17 were located in the outer zones of lungs and 6 in the inner zones.The double reading showed a detection rate of 59.1% ( 152/257 )and a missed rate of 40.9% ( 105/257),which was significantly lower than CAD.The diameter of all the 105 missed nodules by radiologists were ranged from 2.4 to 11.8 mm,in which 94 nodules were solid,10 were partly solid and 1 was nonsolid,with 69 located in outer zones of lungs and 36 in the inner zones. Conclusions The capability of the CAD system for detecting non-calcified pulmonary nodules is superior to double reading in low-dose screening CT examination,especially for the nodules located in the inner zone of the lung.When lung VCAR is used,nonsolid pulmonary nodules are more easily missed so that it should be paid more attentions by radiologists.