Objective To compare differences in pathological grade,clinical classification and prognosis in patients with Henoch?Sch?nlen purpu?ra nephritis(HSPN)in each age group. Methods Totally 225 cases of patients diagnosed as HSPN and treated in the hospital were selected to ret?rospectively analyze their clinical manifestations,pathological classification and prognosis and compare the difference in pathological grade,clinical classification and prognosis by age. Results Of the concomitant symptoms of HSPN,the incidence rate of abdominal pain was the highest in pa?tients of school age. There was statistical significance in the incidence rate of gastrointestinal bleeding between each age group. Of the clinical mani?festations,proteinuria was positive correlated with the pathological type,and the difference was statistically significant(r=0.471,P<0.000 1). But there was no correlation between the count of urine red blood cells in the urine and the pathological type. There was difference in the pathological grade between each age group(H=19.194,P<0.000 1). The difference mainly showed in the pathological grade between adults,children of pre?school age and adolescents(Z=-2.702,P=0.001;Z=-3.675,P<0.000 1). There was difference in clinical classification between each age group (χ2=36.114,P<0.000 1). The difference mainly showed in clinical manifestations between adults,children of school age and adolescents(χ2=19.628,P<0.000 1;χ2=18.944,P<0.000 1). For both children and adults who had developed into chronic renal failure,the renal pathology of these patients was not significantly different. Conclusion Compared with adults,children have milder pathological types and clinical manifestations and well prognosis of HSPN,and the most important factor which affects the prognosis is pathological type and urine protein can reflect the serious?ness of pathological type.

Objective To improve the curative effect of advanced schistosomiasis patients with ascites and HBV infection. Methods A total of 27 advanced schistosomiasis patients with ascites and HBV infection were selected as a trial group and giv?en with anti?HBV treatment and 31 corresponding patients were as the controls and did not received anti?HBV treatment from February 2003 to December 2012. Results The incidence of ascites recurrence spontaneous peritonitis hepatic encephalopa?thy hepatorenal syndrome upper gastrointestinal bleeding and primary liver cancer in the trial group were significantly lower than those in the control group. The detection indexes of liver function renal function and prothrombin time in the trial group were superior to those in the control group. The mortality in the treatment group was also significantly lower than that in the con?trol group. Conclusion The anti?HBV treatment in the advanced schistosomiasis patients with ascites and HBV infection can obviously improve their physical conditions the survival rate and their life qualities.

Objective To quantitatively evaluate the thickness of the buccal cortical bone in the posterior region of the maxillary for orthodontic micro‐implants in children .Methods Forty children (20 males and 20 females) in permanent dentition with Class Ⅱdivision 1 malocclusion were selected .The maxillary posterior alveolar bones of the subjects were scanned and reconstructed by cone‐beam computed tomography (CBCT) .The thickness of the cortical bone between the dental roots of the second upper premolar and the first upper molar at the height of 3 ,4 ,5 ,6 ,7 ,8 ,9 mm from the alveolar crest were determined .The data were analyzed sta‐tistically .Results The thickness of the cortical bone between the second upper premolar and the first upper molar was minimum at the height of 4 mm from the alveolar crest(P<0 .05) .The thickness of the cortical bone increased along with the distance increas‐ing from the alveolar crest at the height of 5 mm .The cortical bones in male were significantly thicker than those in female at the height of 7 ,8 ,9 mm (P<0 .05) .Conclusion The thickness of the buccal corticalbone in children in permanent dentition with ClassⅡ division 1 malocclusion changes with the measured vertical position .Micro‐implant anchorage is better to be placed in the area with a distance of 5 mm from the alveolar crest .

Biochemotherapy refers to the combination of biotherapy and chemotherapy,and it has been rapidly developed since its emergence.Biochemotherapy has brought both new therapies and new therapeutic ideas for the treatment of malignant tumors.In this article,we reviewed the recent advances in tumor biochemotherapies,including expansion of the indications,retaining of therapy even when tumor progressed(unique to biochemotherapy),and reversal of chemotherapy resistance by targeted therapy,the predicting response to tumor biochemotherapy,recent clinical trials of immunotherapy-based chemotherapy,and evaluation criteria for assessment of biochemotherapy response,and so on.

Objective The study implemented the co-word approach to analyze Chinese literatures on feeding behavior published over the recent fifteen years, aiming to explore the research status and progress of the field and provide a foundation for further studies. Methods Literatures on the Chinese National Knowledge Integrated Database were searched using feeding behavior as theme and limiting published time fromJanuary 1,2001toJanuary 18,2017.those fitting in the criteria were included into the study. Keywords statistics and analysis were conducted by using Excel, and a co-occurrence analysis diagram was drawn by using Ucinet 6.237 and Netdraw to visualize the co-occurrence between frequently occurred keywords. Results A total of 467 literatures were included and 28 frequently occurred keywords were extracted for co-word analysis, revealing the correlations between the keywords. The results showed that the studies on feeding behavior in China had focused on infant, nutritional status, breastfeeding, complementary feeding and so on. The feeding difficulty, eating behavior, feeding behaviors for sick children had remained to be studied. Conclusion Domestic research on the current feeding behavior of caregivers is not yet comprehensive .There is an urgent need for a major parental feeding behavior scale for infants and young children, which is the main tool for assessing the feeding behavior of infants and young children. It provides scientific basis for feeding behavior problems and intervention.

0.05).The oxygen and carbon dioxide GEE from periphery arterovenous blood positively correlated with that from pulmonary arterovenous blood(P

Objective To observe the long?term efficacy of neoadjuvant chemotherapy followed by intensity?modulated radiation therapy. Methods A retrospective analysis was performed on the data of 183 patients with locally advanced NPC who were hospitalized in our hospital:96 cases in the observation group, 87 cases in the con?trol group. Results There were no significant differences between the observation group and the control group in terms of five?year OS (77.1%vs. 78.2%, P=0.861), DMFS(89.6%vs. 90.8%, P=0.782), RFS (78.1%vs. 77%, P=0.857) and PFS (72.9%vs. 71.3%, P=0.803). Compared with the control group, the observation group did not sig?nificantly improve 5?year OS, DMFS, RFS and PFS in T3?4N0?1 patients and also did not improve 5?year OS, DMFS, RFS and PFS in T1?4N2?3 patients. There were significantly larger numbers of individuals with adverse reactions in the observation group than in the control group. Conclusions Compared with the long?term efficacy in the patients with locally advanced NPC between neoadjuvant chemotherapy followed by intensity?modulated radiation therapy with concurrent chemotherapy and intensity?modulated radiation therapy with concurrent chemotherapy, the progno?sis has no significantly differences and neoadjuvant chemotherapy followed by intensity?modulated radiation therapy with concurrent chemotherapy leads to a larger number of adverse reactions. The action of neoadjuvant chemothera?py followed by intensity?modulated radiation therapy with concurrent chemotherapy in treatment of locally advanced NPC needs more research.

"Be cautious alone"is a important idea of Confucianists,it means that one should be very cautious to obey every moral standard and not to do any immoral things when he is being alone.The character of purchasing and the particularity of Medical substances demand that Medical substances buyers must be cautious when being alone."Be cautious alone"may help buyers to increase their self-discipline and arouse their vigilance to check erroneous ideas at the outset,and help them to culture a harmonious purchaseing idea.

Objective: To observe the therapeutic effect of 153Sm-clodronate on nude mice orthotopically transplanted with human osteosarcoma. Methods: Severe combined immune deficiency (SCID) mice were subcutaneously inoculated with human osteosarcoma cell line HOS-8603. The formed tumors were then transplanted into BALB/c nude mice at the tibia for passage; the tumors were harvested for establishing orthotopical mice model of human osteosarcoma. Mice treated with 153Sm-EDTMP and clodronate group served as controls. The distribution of 153Sm-clodronate was determined 24 h later. The appearance, tumor weights, X-ray examination, histological observation, and survival of mice were compared between the 3 groups. Results: It showed that the distribution of 153Sm-clodronate in the lesion bone was much higher than that in other organs, with the radioactive ratio of lesion bone to blood being 4 627.1 : 1, lesion bone to normal bone being 10.8 : 1, and normal bone to liver being 8. 4 : 1. 153Sm clodronate treated mice had a slighter osteolytic reaction and a longer survival period, but the tumor mass was not significantly different compared with those of the control group. Conclusion: 153Sm-clodronate gathers at the lesion bone and it has good therapeutic effect on the mice model of human oscosarcoma, making it a promising agent for treatment of bone tumor.

Objective To explore the development of the cross sign of olivepontocerebellar atrophy(OPCA) and its diagnostic value.Methods The clinical and imaging data of 8 patients with OPCA were analyzed retrospec-tively.MRI imaging used SE sequence,plain T1 WI,T2 WI,axial,coronal,sagittal imaging.Results All patients were hide onset.The major clinical presentation was cerebellar atsxia and autonomic nerve dysfunction.Positive radiographic findings were consistent with clinical presentation,mainly for the brain stem atrophy,8 patients of the group had this performance,followed by cerebellar atrophy,6 patients had symmetrical atrophy and 2 patients had asymmetric atro-phy.6 patients after onset of 1.5 -3 years showed a typical cross.Conclusion The cross sign gradually appears at a certain stage of development,and it has high specificity.So the combination of clinical and MRI is valuable for the diagnosis and differential diagnosis of OPCA.