Objective To observe the curative effect of Weifuchun combined with Shenqifuzheng pills in the treatment of chronic atrophic gastritis.Methods 85 cases patients were divided into the control group of 42 cases and the treatment group of 43 cases.The control group were treated with omeprazole enteric -coated capsules and colloidal bismmth pectin,while the treatment group were treated with Weifuchun and Shenqifuzheng pills.The course of treatment was two months.The patients were treated by endoscopy and pathological review after the treatment,then the datas were comparedwith that before treatment.Results The total effective rate of the treatment group was 67.44%,which of the control group was 40.48%,the was statistically significant difference between the two groups (χ2 =6.22,P <0.05).The symptom scores of stomach tingling,stomach fullness,facial darkness,anorexia and melena in the two groups had statistically significant differences (t =6.14,P <0.05).Conclusion Weifuchun combined with Shenqi-fuzheng pills have good curative effect in the treatment of chronic atrophic gastritis.It should be popularized in clinic.

A cutaneous branch of the suprascapular nerve was observed in 9 from 180 Chinese adult arms (5.0?1.62%), it has been found bilaterally in 3, and unilaterally in other 3 male cadavers.The cutaneous branch arose from the stem of an essentially normal suprascapular nerve under the superior transverse scapular ligament. After passing between the coraco-clavicular and coraco-acromial ligaments the cutaneous branch pierced obliquely the deltoid muscle and supplied the proximal third of the antero-lateral aspect of the arm. The distribution territory of the cutaneous branch coincided with the anterior half of the deltoid muscle.

Child ; Child, Preschool ; China ; epidemiology ; Data Collection ; Health Policy ; Humans ; Infant ; Infant, Newborn ; Lead ; blood ; toxicity ; Lead Poisoning ; blood ; complications ; epidemiology ; prevention & control ; Risk Factors

Adult ; Angina Pectoris ; etiology ; Aortic Valve Insufficiency ; complications ; Bradycardia ; etiology ; Female ; Heart Valve Prosthesis ; Humans ; Prosthesis Failure

One hundred upper limbs of Chinese children of about ten years old weredissected for the study of their arterial branches forming the superficialvolar arch.The arches were divided into four types:1)radial arterial type,2)radial-ulnar arterial type,3)median-ulnar arterial type and 4)archlesstype.The first type has the highest percentage of 46%,the second one comesnext with 34%.The archless cases occupy 19%,and only in 1% was thearch formed by branches of the median and ulnar arteries.

The branches of the a. iliaca int. and ext. of 60 Chinese male adult cadavers (120sides) were studied and the findings are as follows: 1. The average length of the internal iliac trunk is 4.35?0.17cm,?=?1.34cm,in the left, and 4.56?0.21cm,?=?1.63 cm in the right. It is inversely proportionalto the average length of the common iliac artery. 2. The patterns of the branching of the superior, inferior gluteal and internalpudendal artieries may be classified into 5 types: type Ⅰ is present in 63 sides (cases)(52.5?4.55%); type Ⅱ and Ⅲ occur in 26 cases (21.67?3.76%); type Ⅳ occursin 4 cases (3.33?1.64%) and type Ⅴ is present only in 1 side (0.85 0.83%). 3. In most of the cases, the superior gluteal artery passes between the lumbosacraltrunk and the first sacral nerve (79.83%), while the inferior gluteal (66.67%) and theinternal pudendal artery (62.19%) usually pass between the second and third sacralnerve into the gluteal region. A few of these vessels may divide into 2 or 3 branchesbefore leaving the pelvis. 4. The accessory pudendal artery is present in 13 cases (10.83?2.83%). 5. The obturator artery originates from the internal iliac artery in 102 cases(85.0?3.26%), most of them spring from the anterior trunk of the internal iliacartery. In the other 18 cases, 2 spring directly from the external iliac artery (1.67?1.17%), 13 from the inferior epigastric artery (10.83?2.85%), and 3 have doubleorigins (2.5?1.42%), in which the 2 branches spring separately from the internal iliacand inferior epigastric artery. These abnormal obturator arteries occur in 14 cadavers(23.33?5.44%). 6. The iliolumbar artery is present in 80 cases (66.67?4.30%) as a singlebranch, in 37 cases (30.83?4.2%) with 2 separate branches and in 3 cases (2.5?1.43%) with 3 branches. It has various origins, most of them spring from the maintrunk or from the posterior trunk of the internal iliac artery. 7. The lateral sacral artery occurs in 54 cases (45.0?4.54%) as a single branch,in 57 cases (47.5?4.55%) with 2 branches, and in 9 cases (7.5?2.44%) with 3branches. Its origin is comparatively constant, usually arising from the posterior trunkof the internal iliac artery. 8. Most of the superior vesical arteries spring from the root of the umbilical artery.The number of branches of this vessel varies from 1 to 6, but most of them have 1 (46cases, 38.33?4.43%) or 2 (45 cases, 37.5?4.42%) branches. 9. The inferior vesical artery has 1--3 branches. Most of them have a singlebranch (104 cases, 86.67?3.1%), it springs commonly from the anterior trunk of theinternal iliac artery or from the internal pudendal artery. 10. The deferent artery springs in 85 cases (70.83?4.15%) as a single branch,and in 35 (29.17?4.15%) with 2 branches. In the single-branch type it springsmostly from the root of the umbilical artery, and in the two-branch type both springcommonly from the superior vesical artery. 11. The inferior rectal (middle hemorrhoidal) artery is present only in 106 cases(88.33?2.93%), most of them spring from the internal pudendal and inferior glutealarteries. In 3 cadavers (5.0?1.99%) they spring from the middle sacral artery sym-metrically. 12. In 103 cases (85.85?3.32%) the inferior epigastric artery springs indepen-dently from the external iliac artery, in 16 cases (13.33?3.13%) it springs as a com-mon trunk with the obturator artery, and in one side (0.83?0.83%) with the medialfemoral circumflex artery. Its origin-site on the external iliac artery is proxmal to theinguinal ligament in 69 cases (57.5?4.51%) with an average distance of 0.95?0.10cm,?=?0.59cm in the left, and 0.73?0.08 cm,?=?0.43 cm in the right; in 43cases (35.83?4.67%) the origin-site is just behind the ligament; and in 8 cases(6.67?2.28%) it is distal to the ligament, its average distance is 0.48?0.09 cm,?=?0.18 cm in the left, and 0.45?0.11 cm,?=?0.22 cm in the right. 13. The deep iliac circumflex artery, a single branch, is present in 115 cases(95.83?1.82%), the remaining 5 cases (4.17?1.82%) have 2 branches. In 54cases (45.0?4.54%) its origin-site is just behind the inguinal ligament; in 36 cases(30.0?4.18%) is proximal to the ligament with an average distance of 0.56?0.09cm,?=?0.38 cm in the left, and 0.61?0.09 cm,?=?0.35 cm in the right; and in25 cases (20.83?3.72%) it is distal to the ligament, the average distance shows0.62?0.12 cm,?=?0.45 cm in the left, and 0.69?0.12 cm,?=?0.41 cm in theright.

Object To prepare and study a suitable carrier for paclitaxel in water. Methods Cetyl chitosan (CTCS), prepared by reacting chitosan (CS) with chlorocetane under alkaline condition, was soluble and spontaneously formed nanosphere about 100 nm in diameter. And the release in vitro from paclitaxel loaded CTCS nanosphere was measured in phosphate buffer solution (PBS, pH=7 4). Results The balanced release concentration of paclitaxel was deceased and half release time (t 1/2 ) was delayed with the increase of substitution degree of alkyl. Conclusion This kind of nanosphere is an excellent carrier for paclitaxel in water.

Objective To analyze the clinical efficacy and adverse reactions of desloratadine citrate decre-mental therapy in treatment of chronic urticaria.Methods 162 cases of patients with chronic urticaria were selected, they were randomly divided into observation group and control group.Control group was given routine treatment of desloratadine citrate capsule,while the observation group was given desloratadine citrate capsule decreasing therapy, the therapeutic effect and the levels of serum immunoglobulins were compared between the two groups.Results After treatment,the total effective rate of the observation group was 95.06%,there was no significant difference compared with 92.59% of the control group (χ2 =3.254,P >0.05);Two weeks and four weeks after treatment,IgE levels were significantly lower than before treatment,there were significant difference (t =8.291,7.931,6.936,5.152,all P <0.05),and the observation group change was more significant,the differences between the two groups were statistically significant (t =7.913,8.136,all P <0.05).After treatment symptom score was significantly lower than before treat-ment,and there were significant difference (t =7.519,8.015,all P <0.05),but the differences between groups were not significant (t =3.152,2.781,all P >0.05).The recurrence rate in the treatment group was 19.75%,which was significantly lower than the 40.74% of the control group,the difference between the two groups was statistically signif-icant (χ2 =6.914,P <0.05).But there was no significant difference in the incidence of adverse reactions between the two groups (χ2 =1.927,P >0.05).Conclusion Desloratadine citrate capsules in treatment of chronic urticaria can not only obtain more effective clinical curative effect,but also has less toxic side effect.For the purposes of the application method of the drug,decreasing method compared with conventional medication therapy can effectively improve the level of serum IgE.Therefore,it is worthy of clinical application.

Objective To investigate the effect of thiopental sodium (TPS) on spontaneous and KCl-evoked glutamate release from prefrontal cortical synaptosomes in rats and the effect of bicuculline on this effect ofTPS.Methods SD rats of both sexes (200-250 g) were decapitated and brains were removed. The prefrontalcortex was dissected and added to ice-cold sucrose solution and homogenized. The homogenate was centrifuged at1000 g at 0℃-4℃ for 5 min. The supernatant was again centrifuged at 12 000 g for 20 min. The sediment wascrude synaptosomes, which was added to artificial cerebro-spinal fluid (ACSF). The crude synaptosomes weredivided into 5 groups (n = 8): control group and 4 TPS groups. In control group no TPS was added while in TPSgroups different concentrations of TPS was added and the final concentration of TPS was 10, 30, 100, 300?mol?L~(-1) respectively. The synaptosomes were then placed with or without KCl in water bath at 37℃ for 15 min. Thespontaneous or KCl-evoked glutamate release was measured using high-performance liquid chromatograph (HPLC).In another set of experiment bicuculline 0. 1 mmol?L~(-1) was added to ACSF in each group before 15 min water bathto see if it could antogonize the effect of TPS on glutamate release. Results TPS 30, 100 and 300 ?mol?L~(-1)could significantly inhibit the spontaneous or KCl-evoked glutamate release compared with control group (P0.05). Bicuculline 0. 1 mmol?L~(-1) had no effect on the glutamate release in control group but could antagonize the inhibitory effect of TPS on glutamate release. Afteraddition of bicucculline the glutamate released in control group was not significantly different from that in the TPSgroups.Conclusion TPS sodium can inhibit the spontaneous or KCl-evoked glutamate release from prefrontalcortical synaptosomes in a concentration-dependent manner. The inhibitory effect is mediated by GABA_A receptors.

Objective To investigate the effect of isoflurane pretreatment on hypoxia/reoxygenation (H/R)-induced syndecan-1 shedding from human umbilical vein endothelial cells (HUVECs) . Methods HUVECs were cultured in EMB-2 medium and randomly divided into 3 groups ( n = 32 each) : control group (group C), H/R group and isoflurane pretreatment group (group I). H/R was produced by 4 h exposure of HUVECs to hypoxia followed by 2 h reoxygenation in H/R and I groups. HUVECs were exposed to the mixture of 5% CO2 and 95% O2 for 30 min and then cultured in normal culture atmosphere (21% O2) in group C. In group I, HUVECs were expased to 1.73% isoflurane and incubated for 30 min before H/R. The syndecan-1 expression, concentrations of shed syndecan-1 in the medium, and cell permeability and viability were measured at the end of reoxygenation. Results Compared with group C, the shed syndecan-1 concentration in the medium and cell permeability were significantly increased, while the syndecan-1 expression and cell viability decreased in H/R and Ⅰ groups ( P ＜ 0.01) . Compared with group H/R, the shed syndecan-1 concentration in the medium and cell permeability were significantly decreased, while the syndecan-1 expression and cell viability increased in group Ⅰ (P ＜ 0.01) . Conclusion Isoflurane pretreatment can protect HUVECs against H/R injury through inhibiting the syndecan-1 shedding.