1.Design and Application of Hospital Assessment Information Management System
Chinese Medical Equipment Journal 1993;0(06):-
Objective To assess the medical staff and department from the aspects of basic workload,quality,science & research,education and so on.Methods Some data on the above aspects were extracted from HIS,and some were input manually.Results Some report forms were established on the basis of the above data.Conclusion An assessment platform for medical quality and achievement is constructed.
2.CAUSES OF FALLS IN 107 PATIENTS AND RELATED PREVENTIVE MEASURES
Modern Hospital 2015;(10):71-73
Objective To analyze the causes of falls in 107 patients, and to provide reference for the pre-vention of falls in hospitalized patients .Methods The analysis of hospitalized patients fall down where nursing area , age, fall time, place, disease, carer and the extent of internal medicine , brain and geriatrics is high incidence area of falls in the hospital , the ratio was 75.70%in total;the age of the fall patient ≥60 years old accounted for 81.31%;The high time for fall in the night (47.66%);Ward was the main falls area;Occurrence fall disease of fall patients mainly with cerebral infarction , hypertension, coronary heart disease , diabetes, accounted for 47.67%; In the fall with carer accounted for 71.96%;First grade damage accounted for 49.35%.Conclusion elderly people are the high risk group of falls , and the decline of physiological function and the influence of many diseases and drugs have a close relationship with fall .High time and place of falls in patients hospitalized in the night and ward , fall damage is given priority in mild and no damage , in fall patient with carer rate is higher .So the future hospital with fall preven-tion key points of nursing work should focus on pay close attention to the patient 's physiological status , disease and drug use, strengthen medical personnel to fall early risk assessment and give corresponding intervention measures , pay attention to the ward environment and the safety of facilities , strengthen the nursing management and nursing edu-cation, so as to reduce the occurrence of the event of a fall .
3.The observation of coronary angiography detection in coronary heart disease patients with left ventricular ejection fraction decreasing
Chinese Journal of Primary Medicine and Pharmacy 2010;17(20):2777-2778
Objective To explore coronary angiography detection in coronary heart disease patients with left ventricular ejection fraction decreasing. Methods The clinical data of 120 coronary heart disease patients were retrospectively analyzed. And the patients were divided into observation group and control group by decreasing of left ventricular ejection fraction. Results The incidence rate of more affection, anterior descending branch, convolution branch,left bole affection were higher than control group;The Gensini points of detection group were higher than control group( P < 0. 05) ,and the difference was statistical significance. Conclusion Close attention on the changes of left ventricular ejection fraction in the clinic could provide reliable theory base.
4.Comparison of students' learning curves between Macintosh laryngoscope and Airtraq laryngoscope in endotracheal intubation
Hong ZHAO ; Yi FENG ; Yanyan ZHOU
Chinese Journal of Medical Education Research 2012;11(10):1020-1023
Objective To compare medical students' learning curve between Macintosh laryngoscope and optical laryngoscope in endotracheal intubation and to decide which one is more suitable for novice personnel.Methods Totally 26 interns after being trained by experienced anesthesiologists were enrolled in this study.They performed intubation on 6 patients by using both Macintosh laryngoscope and optical laryngoscope ( each laryngoscope for 3 patients) under the supervision of experienced anesthesiologists.The sequence of laryngoscope was determined by computer-generated random number list.Results Totally 149 patients who were ready to receive surgery under general anesthesia were enrolled in this randomized crossover controlled study.Duration of intubation was significantly shorter in Airtraq group (78 -± 33 ) s than in Macintosh group (114 ± 32) s,P < 0.001.Intubation success rate was significantly higher in Airtraq group than in Macintosh group ( 87.8% vs.66.7%,P < 0.05 ).Conclusions With the advantages of rapid learning curve,higher intubation success rate and shorter intubation duration,Airtraq laryngoscope is easier to master for novice personnel.
5.The establishment of continuous quality improvement management mode and effect evaluation of hospital's project
Luojing ZHOU ; Yanyan HE ; Daxin WANG
Chinese Journal of Medical Science Research Management 2014;27(5):490-493,497
Application of the theory of PDCA cycle to guide to build the hospital's project continuous quality improvement management mode,By Analyzing reasons,optimizing processes,improving the bidding system,regulating the declaration format,increasing of directors' participation,playing the role of expert,and evaluating the effect to continue improving the quality of hospital's project.PDCA cycle method effectively aroused the enthusiasm of young scientific research personnel,and promoted the continuous development of scientific research work.
6.Construction of hemolysin hlyA gene knocked out of cholera vaccine candidate and inserted green fluorescent protein gene
Yanyan ZHOU ; Biao KAN ; Yongyu RUI
The Journal of Practical Medicine 2016;32(3):362-366
Objective To knock down hemolysin hlyA gene and insert green fluorescence protein gene of vibrio cholerae vaccine candidate NFYY101. Methods Amplified fragments of hlyA gene upstream (hlyAup) and downstream (hlyAdown),lacz-GFPuv,and hlyAup-laczGFPuv-hlyAdown, and plasmids treated with specific enzymes were utilized to construct recombinant plasmids pUC18-hlyAup-laczGFPuv-hlyAdown and pCVD442-hlyAup-laczGFPuv-hlyAdown. Following the construction of the recombinant suicide plasmids ,a vaccine candidate was constructed by homologous recombination ,while SM10λpir carrying pCVD442- hlyAup-laczGFPuv-hlyAdown was utilized as the donor strain to transfect NFYY101. Results Construction of recombinant suicide plasmids pCVD442- hlyAup-laczGFPuv-hlyAdown was satisfactory that hemolysin hlyA gene was knocked out and green fluorescence protein gene was successfully inserted of vibrio cholerae vaccine candidate NFYY101. Conclusion Construction of the recombinant suicide plasmid pCVD442-hlyAup-laczGFPuv-hlyAdown successfully can be used for knocked out the hlyA gene and added green fluorescence protein gene as genetic marker into the chromosomal DNA of vibrio cholerae vaccine candidate.
7.The imaging changes of premature infants with periventricular leukomalacia and its influence on prognosis
Fatao LIN ; Zhuoyan ZHOU ; Yanyan SONG
International Journal of Pediatrics 2016;43(1):20-23
Periventricular leukomalacia ( PVL) is the most distinctive and characteristic brain injury in premature infants, which may result in nervous system sequelae, and affect motor development and quality of life of the infants. PVL lacks specific symptoms and the diagnosis of PVL depends on imagine. Transcranial ultrasound could make initial diagnosis and prognostic evaluation for PVL. Combined with MRI, it can assess the degree of the white matter damage and predict the possible adverse consequences, which could provide evi-dence for early treatment. The changes of brain imaging and their impact on the prognosis of PVL in preterm newborn was reviewed in this article.
8.Impact of spontaneously hypertensive diabetes mellitus on myocardial cell structure and cardiac function in rats
Yanyan WANG ; Xunmin CHENG ; Hangbo ZHOU
Journal of Medical Postgraduates 2003;0(11):-
Objective: To observe the impact of spontaneously hypertensive diabetes mellitus(SHDM) on myocardial cell structure and cardiac function.Methods: Twenty-four SD rats were equally divided into an SD(control),a DM,an SH and an SHDM group.DM and SHDM were induced in the SD and SH rats by intraperitoneal injection of streptozotocin combined with high fat diet,followed by invasive detection of the cardiac function and pathological examination of the myocardial cell structure 16 weeks later.Results: Disorganized array,decreased interspaces,scattered degenerate necrosis and damaged mitochondria were observed in the cardiac cells of the SHDM group.The left ventricular end-diastolic pressure(LVEDP) was significantly higher in the SH,DM and SHDM groups than in the SD group(P
9.High-frequency ultrasound guided venipuncture of forearm superficial veins
Yunyan YANG ; Ligang CUI ; Yanyan ZHOU
Chinese Journal of Minimally Invasive Surgery 2005;0(12):-
Objective To assess the value of high-frequency ultrasound guided venipuncture of forearm superficial veins. Methods Forty patients with failure of direct venipuncture were given high-frequency ultrasound guided venipuncture. After the direction and depth of superficial veins were identified by high-frequency ultrasonography, a re-puncture was performed. Real-time ultrasonic guidance was employed in case of necessity. Results High-frequency ultrasound identification was used in 11 patients, and real-time ultrasonic guidance was used in 29 patients. All the procedures were successfully completed on one session. Conclusions High-frequency ultrasound guided venipuncture of superficial veins is a simple method without complications, being worthy of wide clinical application.
10.Effect of Bushen Tiaojing Decoction on Serum Leptin, Insulin and Tes tosterone of Polycystic Ovary Syndrome Model Rats
Guangrong FENG ; Xiaohua HU ; Yanyan ZHOU
Journal of Traditional Chinese Medicine 1993;0(04):-
Objective To observe the effect and mechanism of Bush en Tiaojing Decoction (Decocti on for reinforcing the kidney and regulating the menstruation) on ovulation of p olycystic ovary syndrome (PCOS) rats. Methods Eighty fe male SD rats were made PCOS models and randomized into blank group, model group, metformin group, Bushen Tiaojing Decoction high and low dose group s, with 10 ones in each and the remainders removed. The changes of serum leptin, ins ulin and testosterone in each group were observed. Results In Bushen Tiaoji ng Decoction high and low dose groups, serum leptin, insulin and testosteron e were all decreased. The effect of Bushen Tiaojing Decoction high dose group wa s similar with that of metformin group in decreasing leptin, insulin a nd testosterone. Conclusion Bushen Tiaojing Decoction c ould improve the ovulation of PCOS rats through regulating leptin, insulin , and testosterone.