ObjectiveTo observe the effect of amlodipine besylate combined with benazepril in treatment of old patients with primary hypertension and left ventricular hypertrophy,and analyze the safety.MethodsOne hundred and eight old patients with primary hypertension and left ventricular hypertrophy were divided into observation group(54 cases) and control group(54 cases) by random digits table.The patients in observation group were treated with amlodipine besylate combined with benazepril and the patients in control group were only treated with amlodipine besylate.The levels of blood pressure,interventricular septal thickness(IVST),left ventricular posterior wall (LVPW),left ventricular end-diastolic dimension (LVEDD) and left ventficular mass index(LVMI) before and after treatment for 6 months were measured and compared between two groups.The adverse effects after treatment were compared too.ResultsAfter treatment,the levels of 24hSBP,24hDBP,IVST,LVPW,LVEDD and LVMI were significantly decreased in both groups (P ＜ 0.05).Moreover,the levels of 24hSBP,24hDBP,IVST,LVPW,LVEDD and LVMI after treatment in observation group were significantly lower than those in control group(P ＜ 0.05).There was 1 case ( 1.9％ ) of dry cough,2 cases (3.7％) of mild ankle edema in observation group,while only 2 cases (3.7％) of mild ankle edema in control group.There was no significant difference in adverse effects between two groups (P ＞ 0.05).ConclusionsCompared with amlodipine besylate single treatment,amlodipine besylate combined with benazepril in treatment of old patients with primary hypertension and left ventricular hypertrophy can more effectively control blood pressure and reverse left ventricular hypertrophy.The adverse effects are not increased,which can be applied in clinic.

Ghrelin is involved in the process of feeding behavior and regulation of related energy metabolism,it also modulates the secretion of gonadotropins or transmitters concerning sex hormone releasing.It is considered as the factor connecting the HPG axis and energy metabolism.Body's nutrition has a bearing upon the process of reproductive system's onset and maturation.Adequate body weight is necessary for normal puberty onset.Obese children tend to have an earlier menarche.Ghrelin may pass on the information about nutrition to the hypothamalus in puberty onset.

Th17 is a CD4+ T cell subset that is a new member of Th1 and tH2.Recent studies have shown that it products IL-17A,IL-17F,IL-21 and IL-22,which play an imoortant role in rheumatoid arthritis.systemic lupus erythematosus,systemic sclerosis,inflammatory howel disease.autoimmune myocarditis and other autoimmune diseases.Deepen the understanding of Th17 and Th17 production in the advancement of autoimmune diseases will provide a new basis for future diagnosis.Th17 will become a new target for the treatment of human autoimmune diseases.

There is an extremely shocking tragedy of a real medical case.The cesarean section couldn't be performed on a full-term in-labor woman because the patient's husband refused to sign the operation validation contract,leading to the death of both the will-be mother and the baby.The above case shows a dilemma between protecting patients' rights of life,being cured and operated and protecting the doctors from being prosecuted in medical treatment.

Objective A survey was conducted to explore the relationship between research capacity and clinical practice in local public hospitals.Methods A third grade class A hospital from Yangzhou city was selected as an example;and 357 medical staff were surveyed through a designed questionnaires.Results Data collected by questionnaires was analyzed to understand the relationship between research ability and clinical practice as well as the awareness of the hospital staff.The results showed that the hospital staff realized that such relationship should be positively associated with each other, and mutual penetration.Conclusions Recommendations have been raised to promote research ability, and then enhance the quality of clinical practice.

Objective To assess the medical staff and department from the aspects of basic workload,quality,science & research,education and so on.Methods Some data on the above aspects were extracted from HIS,and some were input manually.Results Some report forms were established on the basis of the above data.Conclusion An assessment platform for medical quality and achievement is constructed.

emphysema(9.7%)、pneumonia(6.2%),every group has obvious difference(P

Objective Studying risk factors of carotid atherosclerosis in metabolic syndrome(MS),and the relative factors with progression of carotid atherosclerosis.Methods A total of 401 elders were included in the present study.MS was defined by the criteria of IDF(219 MS,182 NMS).All subjects were required to have blood pressure monitored.Venous blood was collected after an overnight fast.Total serum cholesterol,triglycerides,high-density lipoprotein cholesterol(HDL),low-density lipoprotein cholesterol(LDL),apolipoprotein B,lipoprotein a,high-sensitive C-reactive protein,and fasting glucose and insulin were tested;insulin sensitivity index and insulin resistant index were estimated.Uria sample was also collected to test microalbumiuria,creatine and Alb/Cr.Carotid atherosclerosis was determined by B-mode ultrasound,and number and diameter of plaques,if present,were measured to obtain an atherosclerosis score.Results The occurrence of carotid atherosclerosis was significantly higher in MS(P

Introduced policy support and research outputs and market demand of stem cell in the major countries.Research papers and Patent of stem cell have been analyzed by SCI-EXPANDED Database and Derwent databases in 1995~2008,so as to provide a useful reference for China.

Biolog EcoPlateTM is a mainstream approach of studying community-level physiological profiles of microbes. To correct misunderstanding and insufficiency of experimental result explanation, we announced an amendment of information extraction of Biolog EcoPlateTM, which included two parts: (1) carbon substrates assortment sheets based on microbial physiological metabolism and ecological function, providing referrence and index for researchers; (2) illustration of how to use assorment sheet and ordination method to find out more information, guiding by environmental concentration principle.