1.Influence of plasma protein on bacterial adhesion to biomaterials
Yanxing LI ; Suhua XIONG ; Yuming ZHAO ; Yunchao HUANG
Chinese Journal of Tissue Engineering Research 2008;12(36):7195-7198
Implant-associated infection is a serious problem in the clinical application of biomaterials.which greatly restricts the generalizatjon of cardiovascular biomaterials,while bacterial adhesion is the initial cause for implant-associated infections of cardiovascular biomaterials.Therefore.the prevention of bacteriaI adhesion to the biomaterials plays a crucial role in the cure of biomaterial center infection.It has reported that human plasma protein influences the bacterial adhesion to biomateriais.Some plasma proteins inhibit bacterial adhesion.whereas some promote jt.Study on the correlation between plasma protein and hacterial adhesion to the biomaterials is of great importance in the prevention and cure of biomaterials center infection.
2.Correlation between electrical stimulus intensity and postoperative complications of puncture trigeminal ganglion radiofrequency thermocoagulation
Yanxing ZHAO ; Yuanzhang TANG ; Huijie YANG ; Jiaxiang NI
The Journal of Practical Medicine 2016;32(19):3194-3196
Objective To investigate the relationship between electrical stimulus intensity and postopera-tive complications of puncture trigeminal ganglion radiofrequency thermocoagulation (PTGRT). Methods 86 pa-tients with trigeminal neuralgia (TN) on the second and the third branch underwent trigeminal ganglion radiofre-quency thermocoagulation in Xuanwu Hospital , Capital Medical University from June 2013 to December 2015 enrolled in this study. Electrical stimulus intensity in surgery and postoperative pain VAS score , numbness score, masseter muscles score and complications were recorded at 0, 24 and 48 hours post-surgery. Correlations among electrical stimulus intensity in surgery and postoperative pain VAS score,numbness score, masseter mus-cles score were analyzed. Result The 86 patients had different degrees of facial numbness , some patients had different degrees of masseter weakness , and 2 patients had mild sialorrhea in two days after PTGRT without serve complications. Eighty-three patients (96.51%) had no pain, and VAS score wass 0 at 0, 24 and 48 hours post-PTGRT. Electrical stimulus intensity in surgery had apparent negative correlation with numbness score at 0 , 24 and 48 hours popst-PTGRT (P < 0.01), with negative correlation with masseter muscles decreasing at 48 hours post-PTGRT (P < 0.05). Conclusion Suitable temperature and time in PTGRT were needed to be chose ac-cording to the electrical stimulus intensity.
3.Relationship between degree of brain injury during perioperative period of liver transplantation and postoperative cognitive dysfunction
Yanxing ZHAO ; Ping CHI ; Yinghao CAO ; Zhefeng QUAN ; Kejun PENG ; Xin LI ; Xiaodong GUO ; Li SUN ; Haiyang LU ; Haili HE ; Dongmei MA
Chinese Journal of Anesthesiology 2018;38(2):138-141
Objective To evaluate the relationship between the degree of brain injury during the perioperative period of liver transplantation and postoperative cognitive dysfunction (POCD).Methods Thirtythree patients,undergoing elective liver transplantation,were enrolled in this study.Before induction of anesthesia (T0),at 5 min before blocking the portal vein (T1),5 min after opening the portal vein (T2),5 min after opening the hepatic artery (T3),and at 24 h after surgery (T4),blood samples were collected from the central vein for determination of the serum concentrations of S1O0β protein and neuron-specific enolase (NSE) by enzyme-linked immunosorbent assay.Patients were divided into POCD group and control group (group C) according to whether POCD happened within 7 days after surgery.Results Compared with the baseline value at T0,the serum concentrations of S100β protein were significantly increased at T2 and T3,and the serum concentrations of NSE was increased at T3 (P<0.05).There was no significant difference in serum concentrations of S100β and NSE at each time point between group POCD and group C (P>0.05).Conclusion The degree of brain injury during the perioperative period of liver transplantation is not the dominant factor for the development of POCD in the patients.