Objective To investigate the TCM constitution and living habit of inhabitant of Guangzhou nansha.Methods 500 inhabitants of Guangzhou nansha in our hospital were determined by questionnaire,including TCM Constitution,eating habit,sleeping habit and exercise habit.Results There were 26 cases of harmonious constitution(5.2％),474 cases of partial constitution(94.8％).Among the partial constitution,there were 211 cases of single-side constitution (42.2％),the frequency order from high to low was Qi deficiency constitution (12.8％),dampness heat constitution (8％),yang deficiency constitution (6.2％); 179 cases of two-side constitution(35.8％),the sequence was qi deficiency with phlem-dampness constitution (6.2％),Qi deficiency with dampness heat constitution (4.2％),Qi deficiency with Yin deficiency constitution (3.8％).Eating habit (x2=22.449),sleeping habit (x2=17.726) and exercise habit (x2=16.207) had significant dependablity with partial constitution (P＜0.01).Conclusion The main TCM constitution of inhabitant of Guangzhou nansha was Qi deficiency constitution,dampness-heat constitution,Yang deficiency constitution,phlegm-dampness constitution.Partial constitution was closely related with living habit.

Objective To observe the traditional Chinese medicine (TCM) and umbilical treatment on diarrhea-predominant irritable bowel syndrome(IBS-D)with mental disorders. Methods Thirty-seven cases with IBS-D were randomized into a treatment group(33 cases) and a control group(31 cases). The treatment group was given Shugan-Jianpi TCM decoction and pepper umbilical dressing. The control group was given Pinaverium Bromide Tablets and Flupentixol and Melitracen tablets. After having been treated for 4 weeks, Hamilton Anxiety Scale(HAMA), Hamilton Depression Scale(HAMD), IBS Symptom Severity Scale(IBS-SSS), IBS quality of life questionnaire (IBS-QOL) were determined. Results After the treatment, HAMD, HAMA, IBS-SSS in the treatment group and the control group all significantly decreased (the treatment group t=14.280, 13.530, 18.847,the control group t=11.514, 9.424, 13.829, P<0.01), and IBS-QOL increased markedly(t=-16.848, -11.712, P<0.01). Compared with HAMA, IBS-SSS and IBS-QOL in treatment group, the control group showed statistical difference(t=-3.183, -2.549, 3.904, P<0.01 or 0.05). The total effective rate of the treatment group was 94%higher than 75%of the control group(χ2=4.727, P<0.05). Conclusion Shugan-Jianpi TCM decoction and pepper umbilical dressing can improve the clinical symptoms and psychological symptoms and improve the quality of life of IBS-D patients.

Objective: To investigate the effect of multi-stent assisted coil embolization for blood blister-like aneurysms (BBA) and the impact on vascular endothelial function. Methods: Multi-stent assisted coil embolization was performed on 31 patients with internal carotid artery BBA. The effect of embolization was evaluated with Raymand classification on the day after operation. And the prognosis was evaluated using modified Rankin scale (mRS) 28 days and 3 months postoperatively during follow-up. The levels of plasma endothelin-1 (ET-1), von Willebrand factor (vWF) and serum nitric oxide (NO) in peripheral blood of patients were compared before and 1 week after operation through statistical methods. Results: The technical success rate of multi-stent assisted coil embolization was 93.55% (29/31). Among 29 patients who underwent successful BBA embolization, Raymand classification results showed that the effective rate of embolization (proportion of grade and Ⅱ) was 100% (29/29) with 22 cases of grade and 7 cases of grade Ⅱ. Twenty-eight days after operation, mRS showed good prognosis (grade 0-2) in 68.97% (20/29) patients, incluing 5 cases of grade 0, 8 cases of grade 1 and 7 cases of grade 2. And the proportion of good prognosis was 75.86% (22/29) 3 months after operation, with 7 cases of grade 0, 12 cases of grade 1 and 3 cases of grade 2. The levels of ET-1 ([518.38±22.91]pg/ml vs [550.32±28.57]pg/ml, t=-4.848, P<0.001), vWF ([1.66±0.20]ng/ml vs [1.86±0.29]ng/ml, t=-3.161, P=0.002) significantly increased, while the serum NO level significantly decreased ([37.40±4.88]nmol/ml vs [33.02±4.24]nmol/ml, t=3.796, P<0.001) 1 week after operation compared with preoperative results in all 31 patients. Conclusion: Multi-stent assisted coil embolization for the treatment of internal carotid artery BBA is effective, but may bring certain adverse impact on postoperative vascular endothelial function.

Objective To evaluate the immunogenicity and safety of a split-virion influenza vac-cine after its manufacturing process was improved. Methods The immunological non-inferiority of trial to control vaccines was evaluated in 240 subjects aged 3-<18 years. Another 360 subjects aged 18-<60 years were randomly divided into three groups that were respectively given three consecutive lots of trail vaccine to assess the consistency of immunogenicity. Results There were 4. 17% of the subjects aged 3-<18 years showed adverse reactions following immunization with trail vaccine and it was not significantly different from that of the control group (P>0. 05). No significant difference in seroconversion rate, geometric mean titer (GMT) of haemagglutination inhibition antibodies(HIAb) or protection rate was found between trial and control groups (P>0. 05). No significant difference in seroconversion rate or HIAb GMT was found among the three lots (P>0. 05). Conclusion The trial influenza vaccine has good safety, immunogenicity and lot-to-lot consistency after the manufacturing process was improved.