Due to lack of cost accounting,the scientific researches charge differently of experimental animals in every hospital.Animals feeding costs include two parts,direct costs and indirect costs.Through gathering statistics of different kinds of animals and cumulative feeding amounts of different researches,the article calculates the indirect costs of each research,this approach can make up deficiencies for the current management method and improve hospital management level.

Objective To observe the clinical effects of dialectical treatment of acute hemoptysis in lung cancer. Methods A total of 289 patients with acute hemoptysis in lung cancer were randomly recruited into the two groups: a experimental group with 149 patients and a control group with 140 patients. The experimental group was treated on TCM syndrome differentiation, while the control group was treated with conventional western medicine. Results In the experimental group, the total effective rate was 91.3%. While in the control group, the total effective rate was 63.6% (χ~2= 32.13, P<0.01). There was significant difference between the two groups. Conclusion Dialectical treatment of acute hemoptysis in lung cancer is effective.

Objective To explore the clinical application value of the serum GP73 detection in the diagnosis of hepatocellular car-cinoma(HCC).Methods The expression level of serum GP73 protein was quantitatively detected by ELISA,including 52 cases of healthy individuals,45 cases of non-hepatic disease,43 cases of viral hepatitis B,20 cases of liver cirrhosis and 30 cases of HCC;The levels of GP73 were compared among the 5 groups.Serum a-fetoprotein(AFP)level in the HCC patients was detected by electro-chemilumnescence(ECL)method.The area of receiver operating curve(ROC),sensitivity and specificity of GP73 and AFP for diag-nosing HCC were calculated.Results The serum level of GP73 was (58.57 ± 35.64)ng/mL in the non-hepatic disease group, (70.36±49.88)ng/mL in the viral hepatitis B group,(114.47±51.27)ng/mL in the liver cirrhosis group and (251.37±95.6)ng/mL in the HCC group,which in the patients was significantly higher than(34.03±15.20)ng/mL in the healthy control group,the differences had statistical significance(P <0.05);The serum GP73 level in the HCC group was significantly higher than that in the other groups with statistical difference(P <0.01);The positive detection rate of serum GP73 in the HCC group was 76.7%,which was significantly higher than 3.12% in the non-HCC group,the difference had statistical significance(χ2 =108,P <0.05);The sen-sitivity and specificity of GP73 for diagnosing HCC were 75.1% and 94.9% respectively,which were significantly higher than those of the AFP(52.3% and 86.6%).Conclusion GP73 could be to become a better serum marker for diagnosing HCC.

Objective To study the correlation between serum hepatocyte growth factor and Urinary viable tubular cells count in patients with acute renal failure and to evaluate the clinical significance.Methods Serum HGF levels were determined by ELISA and the number of viable tubular cells in urine was determined by trypan blue in 25 patients with ARF at the stages of oliguria,polyuria and convalescence.The relationship between serum HGF levels,the number of viable tubular cell and renal function was studied.Results Compared with the 9th day from the occurrence of ARF,the HGF levels in the serum increased significantly at the 1th day in the ARF patients.There was significant positive correlation between BUN or SCr and the serum HGF in urine in patients with acute renal failure.Conclusion Serum HGF in ARF patients increased significantly and tended to rise at first but dropped afterwards,which reflected the course of renal injury and the recovery of renal epithelial cells.The detected viable tubular cells in urine were an early predictive indication of renal function recovering in ARF patients.

Objective:To solve the problems that the accounting treatment of donated business of each hospital was not uniform caused by the imperfect provisions of hospital accounting system.Methods:The relevant systems and policies were comprehensively reviewed and regularly analyzed.Results:The current accounting treatment was contrary to the matching and substance over form principle,which effected the authenticity and accuracy of the financial statements.Conclusion:Social donation was an important way of financing in hospital.It needed to divide the donated fund by limited or not limited,set up related subject and improve hospital accounting system.

Objective To discover the operating problems through analysis of the financial situations of the rehabilitation institutions. Methods According to the different regions and different levels of rehabilitation institutions, 416 representative institutions from 26 provinc-es, municipalities and autonomous regions were surveyed. Results 329 effective questionnaires were recalled. 57.75%institutions relied on the superior departments in charge of funding, 51.09%institutions were in breakeven state. They were lack of sustainable development pow-er, and the capital expenditure was mainly used for staff salaries and equipment purchase. Conclusion To solve the shortage of funds in the development of rehabilitation institutions, we should establish a long-term mechanism of internal and external compensation.

Objective To study the main influence factors of nosocomial infection(NI) and establish a model to predict and forecast the risk of NI on patients in hospitals. Methods Clinical data of 27352 inpatients extracted from hospital information system were sorted out and coded, and a logistic regression model about the probability of NI was established. The risk of NI was divided into four scales. Results With multiple factor analysis,16 risk factors of NI were identified, which were age, high body temperature, numbers of diagnosis, days of staying in hospital and seriousness, numbers of routine test for urine, times of blood transfusion, use or without use of antibiotic and radiotherapy, turning over the bodies or not, relationships between infection and interventional operations, with or without diabetes, categories of diseases based on ICD-9, numbers of interventional operations, type of anesthesia and department of admission. If NI was judged when predicted probability(Pr)of logistic regression model exceeded 0 35, the specificity and false diagnostic rate of diagnostic test were 0 995 and 0 005 respectively, and the area under ROC curve was 0 986. According to decision tree method, the risk of NI was classified into four degrees: low (Pr

OBJECTIVE:To ensure safe and efficient drug use.METHODS:Chinese Traditional patent Medicines containing components of pharmaceutical chemicals collected in the Newly Edited National Chinese Traditional Patent Medicines were listed and classified statistically.RESULTS:Of the total collected 5 017 Chinese Traditional patent Medicines,160 contained components of pharmaceutical chemicals(3.19%).In which,the coldrex,medicine for relieving cough and asthma,gastrointestinal medicines took the leads.However,some Chinese Traditional patent Medicines instructions failed to indicate the contained contents of pharmaceutical chemicals as specified.CONCLUSIONS:For pharmaceutical manufacturing enterprises,the related information concerning the components of pharmaceutical chemicals should be added in the notes of Chinese Traditional patent Medicines.Doctors and pharmacists should know well about the related information so as to ensure safe and efficient drug use.

Objective:The pathogenesis of placental vascular disease(PVD) was further investigated. Methode:PVD group (study group) and normal pregnancy (control group) were recruited. Two-channel mi-croarray technique was applied to screen the most differently expressive genes of human genome, and veri-fied the different expressions in mRNA and protein levels by quantitative PCR and Westem-blot, also local-ized the expression of different genes in placental tissue by immunohistochemistry. Reeults:HspA6 and Hs-pA1A had extremely higher expression in placentas with PVD than normal pregnancy. These genes both en-coded Hsp70. Hsp70 was mostly expressed in endothelial and smooth muscle cells of placental microves-ssls. The expression of Hsp70 mRNA and protein were up-regulated in placental tissue and microvascular endothelial cells from PVD group compared with normal pregnancy ( P <0.05) ;The expression of Hsp70 mR-NA and protein had negative correlation with infant birth weight ( P < 0.05). Conclueione:Hsp70 was associ-ated with endothelial activation in the pathogenesis of PVD by initiating an innate immune response and in-flammatory reaction.

The neonatal burst suppression is a severe EEG pattern and always demonstrates serious damage of nerve system. But the outcome of these patients depends on the different etiology. A total of 256 cases of video EEG recordings were analyzed in order to summarize the etiology and outcome of burst suppression. The results showed that some patients in all 17 cases of burst suppression showed EEG improvement. The etiology was the dominant factor in long term outcome. It was suggested that effective video EEG monitoring is helpful for etiologic study and prognosis evaluation.
Electroencephalography/*methods ; Hypoxia-Ischemia, Brain/diagnosis ; Monitoring, Physiologic/methods ; Neonatology/methods ; Video Recording