Objective To investigate the epidemiological features and disease spectrum of inpatients with hepatitis C in recent years and to provide reference for the control of hepatitis C.Methods A retrospective study of demography,epidemiology,and laboratory examination was performed in 1 10 hospitalized patients with hepatitis C.Results Of the 1 10 patients,60 were male and 50 were female,with a male-to-female ratio of 1.2:1.The main transmission routes included blood product transfusion (33.6%),surgery (30.0%),intravenous drug use (14.5%),and sexual transmission (4.5%).The other 19 cases (17.4%)were of unknown transmission route.The annual numbers of cases from 2008 to 2011 were 16,18,32,and 44,respectively.The genotype proportions in patients were as follows:1b,60.7%(17/28);2a,28.6%(8/28);1b/2a mixed type,7.1%(2/28);3b,3.6%(1/28).Of all patients,13.6%(15/110)were found with a-cute hepatitis C,67.3% (74/110)with chronic hepatitis C,19.1% (21/110)with liver cirrhosis,and 10.9% (12/110)with decom-pensated cirrhosis.Conclusion The incidence of HCV infection has been increasing year by year.The major HCV genotypes are 1 b and 2a.Hepatitis C is apt to develop into liver cirrhosis.It is necessary to reinforce monitoring and to carry out specific epidemiological study a-mong the target population.

Objective To investigate the clinical characteristics and risk-factors of traumatic basal ganglia stroke (TBGS) in children.Methods A retrospective case study was conducted to analyze the clinical and imaging data of 16 children with TBGS in the First Hospital of Jilin University from January 2014 to June 2017.A total of 16 TBGS cases (11 males,5 females) were diagnosed and the age ranged from 0.5 to 13.0 years.The prognosis of children with TBGS at different ages (≥5 years and＜5 years) and with different traumatic stroke (infarction and hemorrhage) were compared.Fisher's test was used to compare the prognosis of different groups.Results All cases had clear history of head trauma and varying degrees of limb paralysis after injury,including 4 cases of facial paralysis,3 cases of consciousness disturbance and 1 case of seizures.Head CT scan of the 16 cases showed 11 cases of ischemic stroke and 5 cases of hemorrhagic stroke.Moreover,scattered calcification was observed in the bilateral basal ganglia point of 8 cases.Neurotrophic treatment,microcirculation improvement and nerve rehabilitations were given according to the clinical and imaging data.One patient was treated with craniotomy and hematoma clearance.Of the 16 cases,11 cases were restored to normal,while 3 cases developed limb paralysis and 2 cases died.The prognosis of 11 cases of traumatic basal ganglia infarction (10 cases recovered and 1 case remained hemiplegic) was relatively better than that of 5 cases of hemorrhage (1 case recovered,2 cases remained hemiplegic and 2 cases died) (x2=8.045,P=0.013).In addition,the children younger than 5-year-old (all 8 cases recovered) had a better prognosis than the children older than 5-year-old (8 cases,3 of whom recovered,3 cases remained hemiplegia,2 cases died)(x2=12.121,P＜0.01).Conclusions The anatomical characteristics of basal ganglia and calcification of the lenticulostriate artery are risk-factors for TBGS in children.The prognosis of infarcted children and younger children is relatively better.