1.Retrospective study of the influence of alimentary tract reconstruction after gastrectomy on the blood glucose level in patients with gastric cancers combined with type 2 diabetes mellitus
Huifang WANG ; Gang YE ; Yong WANG ; Xiaogang CHEN ; Yanwen NIU ; Linning LAI ; Aiwen WU
Chinese Journal of Postgraduates of Medicine 2011;34(23):32-34
Objective To explore the influence of alimentary tract reconstruction after gastrectomy on the blood glucose level in patients with gastric cancers combined with type 2 diabetes mellitus. Methods From January 2004 to December 2009, the level of blood glucose and body weight before operation and 1,3,6 months after operation in 87 gastric cancer combined with type 2 diabetes mellims patients were retrospectively analyzed. These patients underwent different alimentary tract reconstructions,including 48 patients for Billroth I after distal subtotal gastrectomy (group A), 39 patients for esophageal Roux-en-Y jejunostomy after total gastrectomy (group B). Fasting blood glucose (FBG) level and body weight of these patients were compared. Results In group A, change of FBG before and after operation were not significant (P > 0.05 ). The levels of FBG in group B were significantly lower in 1,3,6 months after operation [(6.7 ±0.8), (6.6 ±0.6), (6.8 ±0.7) mmol/L] than that before operation [(9.7 ± 1.4) mmol/L](P<0.05). The lower value average difference of FBG at 1,3,6 months was significant between group A and group B (P<0.05 ). In group B, 6 months after operation's total effective rate was 87.2% (34/39). Changes of body weight before and after operation in group A and group B were significant (P < 0.05 ). But between two groups, the changes of body weight between 1,3,6 months and before operation were not significant (P >0.05).Conclusions Esophageal Roux-en-Y jejunostomy after total gastrectomy has obvious influence on FBG level in patients with gastric cancers combined with type 2 diabetes mellitus. It takes about 1 month to reveal the effect of operation and has nothing to do with weight loss.
2.Efficacy of insulin pump therapy of colorectal cancer complicated with type 2 diabetes mellitus in peri-operation period
Leilei WANG ; Sui ZHU ; Xiaoai ZHOU ; Yanwen NIU
China Modern Doctor 2014;(25):122-124,127
Objective To observe the clinical efficacy of control blood glucose by using CSII for the people who suf-fers?from colorectal cancer complicated with type 2 diabetes mellitus in peri-operation period. Methods Sixty patients who sufferred from colorectal cancer complicated with type 2 diabetes mellitus were selected and were randomly divid-ed into treatment group(30 cases) and control group(30 cases). The treatment group was treated with CSII (CSII group), while the control group was treated with conventional subcutaneous injection (MSII group). The blood glucose level be-fore and after treatment, blood glucose time required to reach the target, the incidence of hypoglycemia, insulin dosage, preoperative preparation time, time of hospitalization,the incidence of wound healing, and infection were detected. Re-sults Blood glucose levels of two groups decreased significantly after treatment, which reached effect satisfaction. The time of blood glucose control, the rate of hypoglycemia, insulin dosage, preoperative preparation time, hospitalization time,wound healing and infection rate of group CSII were lower than those of MSII group. Conclusion Efficacy and safety in peri-operative time of CSII in colorectal cancer operation with type 2 diabetes mellitus is superior to that of MSII.
3.Development and application of a fundus transverse microscopic imaging system.
Yunhai ZHANG ; Saisai NIU ; Jiliang ZHU ; Yanwen JIA
Chinese Journal of Medical Instrumentation 2011;35(1):24-27
A human fundus transverse microscopic imaging system based on a MEMS deformable membrane mirror was developed. A 37 element small MEMS deformable membrane mirror was used as wave front corrector in this system. Wavefront errors were measured by a Hartman-Shack wave front sensor which contains 127 micro lens lets. After the wavefront error of human eye had been corrected by the deformable membrane mirror under the control of a computer, the imaging illumination light was triggered by a electronic shutter to illuminate the retina, the images were captured by a CCD camera. It has been showed in model eye's test that the system could measure and correct the eye's wavefront aberration efficiently. The fundus image achieved the diffraction limit after aberration correction. It was showed in clinic that except a few patients with turbid eye, most patients could finish the process of measuring and correcting wavefront aberration and then taking fundus image. The examination process could be finished safely, quickly and reliably.
Diagnostic Imaging
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instrumentation
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methods
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Equipment Design
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Fundus Oculi
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Humans
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Lighting
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Microcomputers
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Ophthalmoscopes
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Photomicrography
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instrumentation
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methods