1.Study of the pragmatic of saliva test cassette to detect the Helicobacter pylori in oral cavity.
Xiaomin WANG ; Yan ZHAO ; Nan CHEN ; Junhong WANG ; Yantong XING ; Gengyue ZHANG
West China Journal of Stomatology 2012;30(5):501-504
OBJECTIVETo study the link of Helicobacter pylori salive test cassette (HPS) and 13C-urea breath test (13C-UBT) on detecting Helicobacter pylori infection of stomach, and the sensitivity as well as specificity should be determined.
METHODSA screening trial of 13C-UBT and HPS tests was carried out 130 patients included 106 positive and 24 negative results of 13C-UBT. As gold standards of 13C-UBT, a comparison study with HPS was evaluated using Bayes formula.
RESULTSThe sensitivity, specificity, accuracy, positive and negative predictive value of HPS was 68.87%, 58.33%, 66.92%, 87.95%, 29.79% respectively. The coincidence was 66.92%.
CONCLUSIONThere is a correlation between results of 13C-UBT and HPS. Combination of 13C-UBT and HPS may compensate the blind zone of 13C-UBT in detecting oral Helicobacter pylori infection. 13C-UBT could not be used as a gold standard to judge the validation of HPS in detecting Helicobacter pylori oral infection. The methods can be used at the same time in clinic.
Bayes Theorem ; Breath Tests ; Helicobacter Infections ; Helicobacter pylori ; Humans ; Mouth ; Saliva ; Sensitivity and Specificity ; Urea