1.Determination of Trace Flow Injection-Catalytic Spectrophotometry
Yanqin ZI ; Lanlan DUAN ; Chunling LU
Chinese Journal of Analytical Chemistry 2001;29(2):186-188
The color fading reation on potassium bromate with Victoria green stand G by the catalysis of nitrite in hydrochloric acid medium was studied. The experimental condition offlow injection spectrophotometric method for the determination of trace NO2- was optimized. The linear range for the determination of nitrite is 0.00~0.30 mg/L and 0.30~ 2.00 mg/L, the solpes of standard curves are 0.708 and 0.339 respectively, the analytical speed is 80/h. It has been used todetermine trace nitrite in the collanae lake water, fishpond water, power plant waste water and well water. The results are satifactory.
2.Progress in research methods or strategies of compatibility mechanism of traditional Chinese medicine prescriptions
Lei ZI ; Yanjuan LI ; Yanqin LI ; Tao WANG ; Junjie HAO ; Jie YU ; Xingxin YANG
China Pharmacy 2023;34(11):1393-1398
Compound formulas of traditional Chinese medicines (TCM), also known as prescription in clinic, refers to a form of medication in which several TCMs are selectively combined according to the certain compatibility principles and the needs of patient’s condition, based on syndrome differentiation and treatment. At present, the methods and strategies for investigating the compatibility mechanisms of TCM prescriptions mainly focus on the following two aspects: analysis of pharmacological substances (including chemical composition analysis of TCM, ingredients of TCM analysis in blood, and pharmacokinetic analysis) and pharmacological signaling pathways analysis (involving network pharmacology analysis, signal pathway indicator detection, and metabolomics analysis). In future research, the compatibility relationships of TCM prescriptions should be explored according to the principles of “Qiqing Hehe”,“ Shengjiang Fuchen”,“ Junchen Zuoshi”, and “Siqi Wuwei”. The regularity of TCM prescriptions compatibility should be shown in the change regularity of chemical components, pharmacokinetics, pharmacological pathways, and chemical compositions of various ratios of TCMs. Based on the insurance of holistic efficacy of TCM prescriptions, the underlying mechanisms of compatibility should be uncovered, which will provide references for the optimization of clinical applications of prescriptions and new directions for the creation of innovative TCM prescriptions.