1.Effect of sodium ozagrel combined with cobamamide and pancreatic kininogenase on diabetic peripheral neuropathy
Clinical Medicine of China 2011;27(6):575-577
Objective To observe curative effect of sodium ozagrel combined with cobamamide and pancreatic kininogenase in patients with diabetic peripheral neuropathy (DNP). Methods Seventy-two diabetes patients with DNP in our hospital from September, 2008 to September, 2010 were randomly divided into observation group and control group. All patients were treated with cobamamide by intramuscular injection and pancreatic kininogenase taken orally. In the observation group sodium ozagrel injection were added to the treatment used in the control group. Results After one course of treatment, the total effective rate in the observation group was 91. 7% (31/36),which was better than the control group (63. 9% ,23/36) (x =7. 6, P<0. 05). Motor nerve conduction velocity of median nerve before and after treatment was (42.9 ± 1.9)m/s and(45. 9 ± 3. 0) m/s in the observation group, and (42. 2 ± 1. 7) m/s and (43. 1 ± 2. 1) m/s in the control group. Motor nerve conduction velocity of peroneal nerve before and after treatment was (34. 9 ± 3. 9) m/s and (46. 1 ±3.0)m/s in the observation group, ,and (35. 6 ±3.4)m/s and(36. 8 ±2. 5)m/s in the control group;Sensory nerve conduction velocity of median nerve was (41.2 ±3.2) m/s and (48. 5 ±4.0) m/s in the observation group,and (41. 5 ±3. 8)m/s and(42.4 ±3. 6) m/s in the control group, sensory nerve conduction velocity of peroneal nerve was(35.4 ±3. 4) m/s and(44. 8 ± 3. 2) m/s in the observation group, and (35. 9 ± 4.4) m/s and(37. 6 ± 3. 3) m/s in the control group. The difference of nerve conduction velocity before and after treatment in the observation group reached the statistical significance(P<0. 05), whereas not significant in the control group (P > 0. 05). After treatment, the nerve conduction velocity in the observation group significant better than those in the control group (P < 0. 05). Conclusion The treatments of sodium ozagrel combined with cobamamide and pancreatic kininogenase in diabetic peripheral neuropathy is safe and effective.
2.The method of communicative English testing in CET
Journal of Chongqing Medical University 2000;25(z1):121-122
The method of Communicative English Testing (MCET) is one of the moder, scientific language testing methods suitable for the principle of quality education. In this article, the writer introduces the theoretical basis, testing content and the application in CET, including the setting and scoring principles by examples on MCET.
3.An Improved Silver Staining Method
Chinese Journal of Cancer Biotherapy 1996;0(04):-
A new modification of Merril's silver staining of proteins in sodium dodecylsulfate polyacrylamide gels is introduced.The use of a prolonged period step after fixation and adjusting of oxidant incubation time considerably decrease the background, therefore increase the sensitivity. The detection limit is fivefold lower than original method.
4.Effects of ganglioside GM3 on proliferation and cell cycle of multiple myeloma cell line U266
Journal of Leukemia & Lymphoma 2017;26(8):457-460
Objective To observe the effect of ganglioside GM3 on the proliferation and cell cycle of multiple myeloma (MM) cell line U266. Methods The experimental groups were treated with 20, 40, 80, 160μmol/L GM3, while the control group was not given GM3. The growth inhibition effect of GM3 on U266 cells after 48 hours were measured by using methyl thiazolyl tetrazolium (MTT) method. The cell cycle was tested by flow cytometry with PI labeling. Results The results indicated that the GM3 displayed anti-proliferative effects on U266 cells in a dose-dependent manner. The cell inhibition rates were (13±4) %, (26± 4) %, (47 ±6) %, (55 ±10) % in different dose of GM3 (20, 40, 80, 160 μmol/L), respectively. There was a difference between the experimental group and the control group (F= 93.063, P< 0.05). At the same time, the cell cycle analysis results showed that the U266 cell ratio in S phase was increased from (22.6 ±3.7) % to (71.5±3.8) %(P<0.01) and in G2/M phase was decreased from (42.6±2.5) %to (0.8±0.6) %(P<0.05) while in G0/G1 phase was not significantly changed. Conclusion GM3 can inhibit the proliferation of MM cell line U266 by blocking them in the S phase.
5.My viewpoints on strategies of international dissemination and development Of traditional Chinese medical culture
International Journal of Traditional Chinese Medicine 2010;32(3):215-216
The development of the international spread of Chinese medicine facing the serious challenge of the global competition with the tentacles of Chinese medica;communication in the world are spreading even wider.How to make countermeasures.seize an opportunity and receive the challenge to improve international competitiveness effectively and promote sound and rapid development of the internationalization of Chinese medicine have become the focus of common attention.In this paper,I'll discuss some problems in the development of the international communication of the culture of Chinese medicine such as the main task and the principles.
6.Multiple enamel pearls on left maxillary third molar: a case report.
Wei DONG ; Yanping ZHAO ; Xiaojie FENG
West China Journal of Stomatology 2014;32(3):310-311
Enamel pearl is an ectopic enamel, which usually occurs in the root bifurcate or approaching enamel-cementum site of the first maxillary molar. A case of multiple enamel pearls on the left maxillary third molar is reported in this paper, and relevant literature was reviewed.
Dental Cementum
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Dental Enamel
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abnormalities
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Humans
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Molar
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Molar, Third
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Tooth Root
7.Clinical application and biocompatibility of the biliary tract stents
Yanping ZHU ; Danna JIANG ; Rui ZHAO
Chinese Journal of Tissue Engineering Research 2007;0(43):-
OBJECTIVE:To introduce the research progress of biliary tract prosthesis,to analyze the reason of complication following stent implantation,and to explore the biocompatibility of various biliary tracts and host. METHODS:We retrieved Medline database (1989/2009) and CNKI (1989/2009) using the computer. According to inclusion and exclusion criteria,the literatures were screened by the first author,and the data were collected,and the quality was evaluated. We described and arranged the treatment progress of biliary tract prosthesis implantation,complication of stent implantation and biocompatibility of biliary tract prosthesis to investigate treatment state,complication and biocompatibility of the biliary tract prosthesis. RESULTS:The literatures were summarized. The bilitary tract prosthesis contains plastic stent,mental stent,silica gel tract stent and degradable polylactic acid stent. The complications of stent implantation included transudation,hemorrhage,perforation and stenosis. Among various stents,the biocompatibility of plastic stent was poor,easy to be blocked,but the price was low,and easy to be taken out. The diameter of mental stent following distension could reach 7-10 mm,with long unobstructed time,but the price was higher compared with the plastic stent. The biocompatibility of silica gel tract stent was good. The silica gel tract had strong decay resistance and pliable texture,which could extend tumor excision range and elevate curative effects. Moreover,complications did not occur such as infection and stenosis of the biliary tract. Biocompatibility of nickel-titanium alloy biliary ducts was significantly better than the stent products,without complications. With the exception of price factor,the biocompatibility of degradable polylactic acid stent was the best,but further studies were needed to observe and study the formation of biliary sludge,stent displacement and blockage,stent degradation products. CONCLUSION:Biliary tract prosthesis implantation can be an important treatment method for stenosis of biliary tract. During treatment,enough preparation is needed prior to implantation according to various clinical symptoms to select suitable stent type. Indications are followed strictly to avoid the occurrence of complications. The biocompatibility of silica gel stent and Ni-Ti alloy stent is good,but the biocompatibility of other stents should be enhanced.
8.Discussion on Training of Postgraduate Students Majoring in Rheumatology
Zhiyi ZHANG ; Yanping ZHAO ; Yifang MEI
Chinese Journal of Medical Education Research 2003;0(02):-
This paper presents a description about training of post-graduate students majoring in rheumatology.The essential knowledge and theory are highly stressed,and the clinical skill,comprehensive ability are also emphasized to encouraging students to bring forth new ideas.Besides cooperation and team spirit are encouraged through group and pair work.
9.Reforming Communicative Methods and Improving Communication Between Teachers and Students
Haihong ZHANG ; Zhiyi ZHANG ; Yanping ZHAO
Chinese Journal of Medical Education Research 2006;0(09):-
Communication is very important in education.This paper combine common factors in effected educative communication with common problems in communication between teachers and students.From systemic and analyzing point of view,discuss promotion of communicative quality that contains surroundings and methods and so on.
10.Medical ethics in medical universities and colleges is the essential component of quality education for students of medical sciences
Yanping ZHAO ; Aihua ZENG ; Weihua HUANGFU
Chinese Journal of Medical Education Research 2005;0(06):-
It is suggested in this article that medical ethics should be conceived as the integral part of quality education for students of medical sciences,based on the high consistency of medical ethics with the quality education in higher educational institutions and its close relationship with the cultivation of the qualities of medical students.