ObjectiveTo study the value of cancer antigen 125(CA125) in the differential diagnosis of patients with pleural effusion.MethodsTwo hundred and twenty-eight patients with pleural effusion were selected and analyzed retrospectively,including 80 cases with malignant pleural effusion,148 cases with benign pleural effusion(including 52 tuberculous pleural effusion,56 inflammatory pleural effusion and 40 transudative pleural effusion).The levels of CA125 in the pleural effusion and serum were detected and compared.ResultsThe level of CA125 in the pleural effusion of 99.56％(227/228 ) of all the patients was higher than that in the serum.The serum CA125 levels of patients with benign and malignant pleural effusion had significant differences[ (92.19 ± 13.51 ) kU/L vs.( 151.72 ± 23.14) kU/L,P ＜ 0.05 ],but the levels of CA125 in the pleural effusion of benign and malignant patients had no significant difference [(710.38 ±66.03) kU/L vs. (3135.64 ±1404.92) kU/L,P ＞0.05].The levels of serum CA125 in the malignant,tuberculous,inflammatory and transudative pleural effusion were (151.72 ± 23.14),(120.86 ±26.92),(58.09 ± 11.60),(111.22 ±34.19) kU/L,respectively,serum CA125 of malignant pleural effusion was significantly higher than that ofinflammatory pleural effusion (P＜ 0.01 ),but the serum CA125 level of malignant pleural effusion had no significant difference compared with that of tuberculous and transudative pleural effusion (P ＞ 0.05).The levels of CA125 in pleural effusion of malignant,tuberculous,inflammatory and transudative pleural effusion were(3135.64 ± 1404.92),(756.30 ±96.42),(626.86 ± 105.55),(814.41 ± 173.28) kU/L,respectively,the level of malignant pleural effusion had no significant difference compared with that of tuberculous,inflammatory and transudative pleural effusion(P ＞0.05).Conclusions The value of CA125 in the diagnosis of pleural effusion is not very significant when it is used alone.The serum CA125 combined with other tumor markers can improve the diagnosis rate of tumor.When it is applied for clinical aided diagnosis,the non specificity of CA125 should be noticed.

There's many close relations between ?-endorphin in nerve endocrine immune net and TCM spleen deficiency;to strengthen their study is helpful to exposing TCM nature,offering new thought and method for researching TCM 5 organs nature,and to further development of combination of TCM and WM.

Objective To investigate the blood levels of amino acids in children aged 0-15 year, with an attempt to provide evidence for evaluating amino acid status and diagnosing metabolic diseases of amino acid.Methods The blood levels of eleven amino acids in 1900 children aged 0-15 years were determined by tandem mass spectrometry (MS/MS). Results The blood levels of leucine & isoleucine, valine, phenylalanine tyrosine,glycine, proline, ornithine, and alanine gradually decreased after birth, reaching the lowest levels at the ages of 4-6 months, and then gradually increased, reaching the normal range at the ages of 7 months-1 year. The blood levels of alanine and glycine reach the second peaks on the ages of 9 years in girls and on 11 years in boys. The blood levels of methionine and arginine were lowest in the first week of age, became highest in 1-3 months, decreased to the normal ranges after 4-6 months, and kept the level afterwards. The ratios between prosomatic amino acid and productive amino acid, between ornithine and arginine, between citrulline and arginine, and between ornithin and citrulline were highest in the first week of age and decreased to normal values after 3 to 12 months. The concentrations of amino acids in group of 7 months-15 years were significantly different from the group of 1 day-1 month and group of 2-6 months (P ＜0. 05 or P ＜0. 01 ). The concentrations of amino acids were significantly higher in females than in males in the group of 1 day-1 month and in all age groups (P ＜0. 05 or P ＜0. 01 ) . Conclusions The concentrations and profiles of amino acids change remarkably during the first year of age. Age should be carefully considered when evaluating the nutritional status of amino acid and diagnosing metabolic diseases of amino acids.

Objective:To explore the role of MVD, bFGF and VEGF in OMFS and the relationship between them. Methods: Immunochemistry streptavidin peroxidase method was used to detect the MVD and the bFGF, VEGF expressions in 57 cases of OMFS samples. Results: MVD, bFGF and VEGF expressions were different between OMFS and benign. The close correlations were found among the expressions of VEGF, bFGF and MVD. Conclusion: The expressions of VEGF and bFGF are associated with MVD which indicated that VEGF and bFGF may play important roles in angiogenesis.

Baishouwu is a traditional tonic Chinese medicinal herb which is rich in Shandong, Liaoning and Jiangsu Privences. Baishouwu mainly contains steroids, polysaccharose, acetophenone, and essential oil, with the efficacy of nourishing liver and kidney, tonifying essence and blood, blackening the beard and hair, and prolonging life. This article retrieved relevant literature in the last decade about biological study, chemical constituents, and pharmacological activities of Baishouwu, with a purpose to provide a scientific basis for its rational researches and development.

0.05).In terms fo LVEF,no differences were found between the 2 groups at 1 week after the operation but patients in the TA group showed higher LVEF at 3 months after the operation compared with the NTA group(P

Polysaccharide is a kind of polymers and composes of monosaccharide molecules.The biological activities of the polysaccharide include the promotion of immunity, anti-tumor, anti-oxidation and anti-aging. The polysaccharide of traditional Chinese medicine has become the research focus due to its safety and low toxicity. Based on the research achievements in recent years, we summarizeds the effects of Herbal Polysaccharides on immune organs, immune cells, immune molecules, and immune regulation mechanism.

Coverage of internal iliac artery during endovascular abdominal aortic aneurysm repair may cause ischemic complications in buttock,intestine,lower extremity and genital.We reported nursing care of 72 patients in our center to investigate the key points of nursing.Our experience were as follows:individualized blood pressure management and doctor-nurse cooperation in pain management were key points in preoperative nursing;close postoperative observation was focused on ischemic colitis,buttock claudication and ischemic buttock skin;cooperation with ostomy care group improved pertinency of nursing care;rounding by integration of doctors and nurses obtained high satisfaction and improved patients' compliance.

L-asparaginase activity produced by six E. coli J53 strains containing different plasmids and plasmid free E. coli J53 strain was compared. The enzyme activity of the plasmid- bearing strains was about 2—4 times lower than that of the plasmid free ones. Curing the R plasmids from E. coli J53, the activity of L-asparaginase increased and was close to that of the plasmid free strain. It is proved that the remarkable inhibition of L-asparaginase activity results from the presence of the plasmid in E. coli.

Objective To compare the advantages and disadvantages of high intensity focused ultrasound (HIFU ) and total abdominal hysterectomy for the treatment of uterine fibroids .Methods 167 patients with symptomatic uterine fibroids were divid‐ed into the HIFU treatment group(n=86) and the hysterectomy group(n=81) .The adverse events were recorded before operation and at postoperative 1 ,3 ,6 months .The questionnaire survey of the uterine fibroid symptoms‐quality of life (UFS‐QOL) was con‐ducted .The health related living quality was evaluated by using the health survey questionnaire‐36(SF‐36) .Results There were no severe adverse events in either group .The significant clinical complications and adverse events in the HIFU group were lower than those in the hysterectomy group .The UFS‐QOL scores in the HIFU group were superior to those in the hysterectomy group ,but the SF‐36 scores at postopertive 3 ,6 months had statistically significant differences between the two groups (P>0 .05) .Conclusion The patients who are unable to tolerate surgery or hope to preserve the uterus and its physiological function are suitable for HI‐FU treatment .