1.Clinical Analysis of Ischemic Colitis in 30 Patients
Chinese Journal of Primary Medicine and Pharmacy 2010;17(4):443-444
Objective To analyze the clinical feature and diagnostic methods of patients with ischemic colitis(IC) for improving the recognition and the efficacy of therapeutic treatment. Methods Retrospective analysis of the clinical data of 30 cases of IC,including the medical history,clinical symptomatology,endoscopic appearance, histopa-thology,treatment and prognosis. Results IC occurred most of frequently in mid-aged and elders,the male-female ra-tio was 1:2.3,83.3% of the patients were over 60 years old, and most them had underlying disease. The most com-mon presenting features were sudden abdominal pain and bloody stools. Endoscopic lesions located mainly in left co-lon. Mucosal edema,erosin and submucosal bleeding were common pathological feature. Vasodilator drugs and compre-hensive medical therapy had good effects. The average duration for healing or improving was 10 days. Conclusions IC should be suspected in all elder patients with sudden abdominal pain and bloody stools. Colonoscopy is helpful for diagnosis. The prognosis is good in most cases and with rapid recovery.
2.Deanxit in adjuvant treatment of non-erosive reflux disease non-responding to proton pump inhibitor
Chinese Journal of Primary Medicine and Pharmacy 2009;16(10):1747-1748
Objective To investigate the efficacy of flupentixol and melitracen(Deanxit) in treatment of non-erosive reflux disease(NERD) and non-responding to proton pump inhibitor. Methods Fifty eight NERD pa-tients were randomly divided into two groups, the treatment group (n = 29) and control group (n = 29). Patients in control group were given esomeprazole 40 mg qd. Patients in the treatment group were given the same drug plus Deanxit 1 Tab qd. The clinical effect was evaluated and scored by Hemihon Anxiety Rating Scale (HAMA) after 4 weeks. Results The total efficacy rate of the treatment group was higher than control group (P < 0.01),and HAMA was lower in the treatment group than in control group (P < 0.01). Conclusions Adjuvant treatment of Deanxit combined with esomeprazole is effective to NERD patients who did not respond to proton pump inhibitor, can greatly improve anxious disorders.
3.The research progress in immune regulation of polysaccharides of traditional Chinese medicine
Yanan CHEN ; Yanmin DONG ; Hui WANG
International Journal of Traditional Chinese Medicine 2016;38(9):855-858
Polysaccharide is a kind of polymers and composes of monosaccharide molecules.The biological activities of the polysaccharide include the promotion of immunity, anti-tumor, anti-oxidation and anti-aging. The polysaccharide of traditional Chinese medicine has become the research focus due to its safety and low toxicity. Based on the research achievements in recent years, we summarizeds the effects of Herbal Polysaccharides on immune organs, immune cells, immune molecules, and immune regulation mechanism.
4.Basic study of fabricating dental prosthesis with laser engineered net shaping (LENS) method——The microstructure of LENS components made from Rene95 alloy
Bo GAO ; Yanmin LI ; Jing CHEN
Journal of Practical Stomatology 2000;0(06):-
objective: To study the effects of laser engineered net shaping(LENS) in the manufacture of dental prosthesis. Methods: An experiment LENS system, including a 5 kW continuous wave CO 2 laser, a four-axes numerical control working table and powder feeding system, was built up, by which, a rectangular LENS component was made from Rene95 alloy powder. The microstructure of the component was observed with scanning electron microscope and ESA analysis. Results: The size of the component was 120 mm?15 mm?15 mm , and the wall of the component was perpendicular to the base. The microstructure of the component was made up of fine columnar dendrite with the length of 10~20 ?m, 10 times less than that of the cast made from the same material. The main elements of the powder distributed homogeneously,the negative effect of segregation could be limited and the properties of the component could be improved.Conclusion: The microstructure of components made by LENS is much better than that of those made by casting from the same material.
5.Basic study of fabricating dental prosthesis with laser engineered net shaping (LENS) method-The mechanical properties of LENS components made from Rene95 alloy
Bo GAO ; Yanmin LI ; Jing CHEN
Journal of Practical Stomatology 2001;0(03):-
Objective: To evaluate the mechanical properties of Rene95 alloy component made by laser engineered net shaping (LENS). Methods: The component was fabricated from Rene95 alloy powder by LENS, then the mechanical properties of the component, Rene95 alloy casting and dental Ni-Cr alloy casting were studied. Results: The tensile strength(MPa), yield strength(MPa), elongations(%) and the microhardness(Hv) of Rene 95 alloy component made by LENS were 1 354.27?63.44, 1 175.29?34.32, 16.53?5.85, and 464.33?10.95, those of Rene95 alloy casting 1 430.28?55.73, 1 145.52?29.78, 10.31?4.25 and 457.56? 11.38, those of dental Ni-Cr alloy casting 612.05?18.46, 426.06?12.70, 6.21?1.21 and 260.14? 6.08, respectively.Conclusion: The mechanical properties of Rene95 alloy component made by LENS were same as those of Rene95 alloy casting, better than dental Ni-Cr alloy casting.
6.The Cytotoxic Effect of ~(103)Pd Particle Radiotherapy Combinded with 41℃ Heating on Human Hepatocarcinoma Cell Line Bel-7402
Liang YE ; Ping CHEN ; Yanmin LIU
Journal of Chinese Physician 2000;0(11):-
Objective To investigate the cytotoxic effect of 103 palladium( 103 Pd) particle radiotherapy combined with 41℃ heating on human hepatocarcinoma cell line Bel-7402. Methods Human hepatocarcinoma cells (Bel-7402) were treated by water-heating and/or 103 Pd particle. The cell growth was determined with MTT assay, and the cell apoptosis was detected by the fluorescent stain of Hoechst33258. Results The cytotoxic effect of 103 Pd radiotherapy combinded with 41℃ heating on Bel-7402 cells was stronger than that of only 103 Pd radiotherapy. Conclusion 103 Pd radiotherapy and 41℃ heating had a synergistic effect on hepatocarcinoma cell Bel-7402, and 103 Pd radiotherapy had the cytotoxic effect on the surviving Bel-7402 cells after hot therapy.
7.Study on balloon dilation of achalasia under painless gastroscopy
Yanmin CHEN ; Qiang GUO ; Hong FAN
Chinese Journal of Digestive Endoscopy 1996;0(06):-
Objective To study on the efficacy and safety of treating achalasia by gastroscopic balloon dilation under anesthesia. Methods Fifteen patients with achalasia were given intravenous propofol and midazolam before dilation. Patient's feeling or distress and operative duration were recorded. The changes of blood pressure (BP) , heart rate ( HR) and blood oxygen saturation ( SpO2 ) were also recorded and analyzed. Results Patients did not complain of any discomfort or pain during gastroscopy. The time of recovery from anesthesia was 17 -27(23. 2) minutes. There were significant changes in clinical scores before and after dilation ( P
8.Pathological Change in Rats'Intestinal Nervous System With Acute Renal Failure and Immunohistochemical Analysis of iNOS
Haichun QIN ; Yanmin CHEN ; Hong FAN
Journal of Chinese Physician 2001;0(10):-
Objective To understand the intestinal nervous system(ENS) pathological change in rats with acute renal failure(ENS).Methods Rat acute renal failure model was established,the intracanthus blood was drew to determine the serum total creatinine(Scr) blood urea nitrogen(BUN) after 48h and 4th-day,then the rats was sacrificed at fourth day each rat's kidney tissue,duodenum,jejunum,ileum,colon and rectum were stained with hematoxylineosin(SE).Finaly, iNOS staining by immunohitochemstry,observed the numbers of the ENS nerve plexus, ENS nerve cell , and iNOS positive cell nerve plexus. Check whether there has hyperemia hydrops, degenerative necrosis, and inflammatory cell infiltration on the mucosa epithelium.Results ⑴Kidney histological change was occurred. The kidney tubules degenerative necrosis was found in all the ten cases of kidney failure, and the hyaline cast, mesenchyme hemorrhagic necrosis, and inflammatory cell infltration were seen. ⑵ HE coloration and microscope inspection;numbers of the ENS nerve plexus and nerve cell of the acute kidney failure group were less than the normal group, especially in the ileum and rectum .⑶The number of the iNOS positive cell nerve plexus in ENS of the rats with acute renal failure was apparently less than that of the normal group. In addition, the iNOS positive presentation was stronger than that of the normal group.Conclusions The findings suggest that toxic metabolites of uremic rat acts on the ENS,and thus leading to pathological changes of ENS,resulting in stomach and intestinal mortor function disorder.
9.The expression of in the tissue of primary bronchogenic carcinoma and its sig nificance nificance//Jia Yanmin, Chen Mingwei, Ma Jianguang
Yanmin JIA ; Mingwei CHEN ; Jianguang MA
Journal of Xi'an Jiaotong University(Medical Sciences) 2000;21(5):428-230
ObjectiveTo détect in the tissue of primary bronchogenic carcinoma(PBC) and discuss its significance. Methods was assessed by immunohistochemical method ot SP in paraffin tissue sections of 40 PBC and paratumor normal lung tissue. Results The positive rate of TNF-a in cytoplasm of carcinoma cells was 47.5 % (19/40), and it was not found in all paratumor normal lung tissue(P< 0.05). ConclusionTNF-a gene expressed in some patients with broncho genic carcinoma. The growth of bronchogenic carcinoma is related to TNF-a gene.
10.Survey of the standardization of medical records writing by physicians
Yanmin CHEN ; Yan LIU ; Yamin LIU
Chinese Journal of Hospital Administration 2011;27(1):12-15
Objective To study the standardization of medical records writing by residents in hospitals. Methods With both quantitative and qualitative analysis, medical records made by residents were sampled in groups to study their standardization. Results Recognition rate of such medical records was 82. 55%, and the excellence rate was 24. 50% in the grade evaluation. For senior residents, their rate of writing excellence falls below those of junior ones; whether the evaluators have medical background bears no significant difference for grade evaluation of medical records writing, yet a significant difference was found with the recognition rate. Conclusion Writing of medical records by residents is found with incompliance now and then, and the recognition rate ought to be improved.