Objective To investigate the death cause of malignant tumors among Inhabitants in Liwan district of Guangzhou city. Methods Mortality rate, standardized mortality rate,Potential Years of Life Lost (PYLL), PYLLR, Standardized Potential Years of Life Lost (SPYLL) and SPYLLR were used to analyze the death cause of malignant tumors. Results The annual average mortality rate of malignant tumors was 198.81 / 105. Among malignant tumors, 1ung cancer taken the 1ead with a mortality rate of 63.08 / 105. The next sequences were as follows: liver cancer, intestine cancer, stomach cancer, nasopharyngeal cancer. The sequence of death causes was mostly influenced by gender and age. The sequences of PYLL rate of main death causes were: liver cancer (0.371%), 1ung cancer (0.353%), nasopharyngeal cancer(0.137%), intestine cancer(0.116%)and mammary cancer(0.090%). Conclusion The mortalities of malignant tumors in Liwan district of Guangzhou city decreased in the past five years while the rank of top 5 cancer sites kept unchanged.

h specific measures of humanistic management from three aspects of the hospital service processes,making it clear the importance and significance of humanistic management in hospital service processes.

Interleukin-15 is a multffunctional cytokine,which are the activating and induction factors of the T-cell,B-cell,NK-cell and lymphokine-activated killer cell (LAK).It can stimulate hematopoietic stem cell proliferation and differentiation,enhance immunity and has anti-tumor effects.IL-15 and IL-2 have similar structures and functions,but many activating effects of IL-15 are stronger than the other's.IL-15 is closely related to tumor development,and has broad application prospects in biological therapy of cancer.

ObjectiveTo investigate the protective effect of testosterone on motor neuron after sciatic nerve injury. MethodsTwelve adult C57 male mice were randomly divided into two groups: the sesame oil control group (n= 6) and the testosterone experimental group (n= 6). Unilateral sciatic nerve cutting severed as the animal model. Following operation, sesame oil or testosterone was administered for the control and experimental animals respectively via subcutaneous injection every other day for two weeks. The number and soma area of the anterior horn motor neurons in the lumbosacral cord of the sciatic nerve injury side were then measured on Nissl stained sections. Results In the testosterone group the motor neurons appeared healthier than that in the sesame control group. The neurons were plumper and showed more processes. Their number and average soma size were significantly larger than that in the sesame control (P<0.01). Conclusion The findings demonstrate that testosterone has a significant protective effect on sciatic nerve motor neurons after nerve injury.

Using the experiences of domestic and other countries on rehabilitation nursing of patients with femoroacetabalar impingement for reference,a balanced rehabilitation procedure was designed and implemented on 16 patients underwent arthroscopic bone forming surgery in acetabulum and femoral head and neck junction.The patients could master the correct metheds of functional exercises.As a result,no postoperative complications occurred.The score of modified Harris hip rating was increased from 62.4 points before surgery to 92.5 points at six months after surgery.

ObjectiveTo examine the characteristic of criminal parenting styles and personality.Methods 379 prisoners took part in by using EMBU and PDQ-4 +.Results ( 1 ) There exist significant difference of parenting styles as parental emotional warmth and understanding,rejection and deny,punishment and strictness among the different criminals type (F =5.70,3.45,3.61,4.66,4.13,2.79,P ＜ 0.01 ).(2) There exist significant difference of total PDQ-4 + scores and the subscales for different type of personality disorder except obsessive-compulsive and schizotypal personality disorder among different criminals type (F =7.67,4.06,14.02,6.94,4.20,4.19,4.01,7.52,7.21,7.21,9.11 ; P ＜ 0.01 or P ＜ 0.05 ). ( 3 ) There were negative correlations between the score in the subscales for different type of personality disorder except obsessive-compulsive personality disorder and the factor of parental emotional warmth and understanding ( r =- 0.12 ～ - 0.32 ; P ＜ 0.01 or P ＜ 0.05 ).And there were positive correlations between the score in the all subscales for different type of personality disorder and the factors of parental rejection and deny,punishment and strictness ( r=0.11 ～ 0.42 ; P＜ 0.01 or P＜ 0.05).(4)Paternal punishment and strictness,maternal emotional warmth and understanding,maternal partiality make a certain prediction about characteristic of criminal personality.ConclusionThere exist different characteristic of criminal parenting styles and personality among different criminal type,and some parenting styles make a certain prediction about characteristic of criminal personality characteristics.

Objective:To observe the protective effect of Shenkang injections in the rats with kidney injury induced by gentamicin. Methods:Forty-eight male SD rats were randomly divided into the control group,model group and treatment group with 16 ones in each. The rats were given gentamicin with intraperitoneal injection(100 mg·kg-1 ·d-1 )for 7 days in the model group and the treat-ment group,and the rats in the treatment group were given Shenkang injections with intraperitoneal injection additionally(2. 0 g·kg-1 ·d-1 ). Eight rats were sacrificed respectively on the 8th and 15th day in each group,and the detection of serum level of creatinine and cystatin-C,urinary concentration of kidney injury molecule-1(Kim-1)and neutrophil gelatinase-associated lipocalin(üGAL),activity of nuclear factor-κβ and Caspase-3,and expression of Bax mRüA and Bcl-2 mRüA in renal tissues as well as the observation of renal tissue apoptosis in each group were conducted. Results:Compared with those in the control group,the serum level of creatinine and cystatin-C,urinary concentration of Kim-1 and üGAL,renal tissue apoptosis,activity of nuclear factor-κβ and Caspase-3,expression of Bax mRüA and Bcl-2 mRüA in renal tissues on both 8th and 15th day were higher in the model group(P<0. 01). The serum level of creatinine and cystatin-C,urinary concentration of Kim-1 and üGAL,renal tissue apoptosis,activity of s nuclear factor-κβand Caspase-3,expression of Bax mRüA in renal tissues in the treatment group were lower at the two time points than those in the model group, while the expression of Bcl-2 mRüA in homogenate renal tissues were higher in the treatment group than that in the model group at the two time points(P<0. 01). All indices were higher at two time points in the treatment than those in the control group. Conclusion:Shenkang injections exhibit protective effect in rats with kidney injury induced by gentamicin through inhibiting renal tissue apoptosis.

Objective To discuss the clinical application value of omeprazole and rabeprazole quadruple therapy on Helicobacter pylori associated peptic ulcer.Methods 360 patients with Helicobacter pylori associated peptic ulcer were selected.They were divided into two groups randomly.The rabeprazole group (180 cases) was treated with rabeprazole with quadruple therapy based,omeprazole group (180 cases) was treated with omeprazole quadruple therapy of short acting as the foundation,to observe and record the two groups of patients with clinical curative effect,the healing rate of ulcer,Helicobacter pylori eradication rate,histopathology and treatment of gastric mucosa during adverse reaction condition.Results The cure rate of rabeprazole group was significantly higher than that of omeprazole group (P ＜ 0.05).Compared the two groups before treatment,upper abdominal pain,abdominal discomfort,belching symptoms,no significant difference,the two groups after treatment in patients with upper abdominal pain,abdominal discomfort and belching percentage of patients decreased,and Rebela was the proportion of patients with lower group (P ＜ 0.05).After treatment,the rabeprazole group of ulcer healing rate 90.5％ (163/180),Helicobacter pylori eradication rate was 87.8％ (158/180),omeprazole group of ulcer healing rate was 70.5％ (127/180),Helicobacter pylori eradication rate was 72.2％ (130/180).The rabeprazole group of the healing rate of ulcer and Helicobacter pylori eradication rate were higher (P ＜ 0.05).Before treatment,there was no significant difference on gastric mucosal histopathological score between two groups.After treatment,two groups of gastric mucosa pathological score were decreased (P ＜ 0.05),no difference between the two groups.During the treatment,there was no significant difference on adverse reactions between two groups.Conclusion Rabeprazole with short acting quadruple therapy can significantly treat Helicobacter pylori causes,promote gastric mucosa repair,improve the clinical symptoms of peptic ulcer,the medication is safe,it is worthy of clinical use.

OBJECTIVE: To explore the factors,general pattern and characteristics of adverse drug reactions(ADR) in children.METHODS: A total of 188 pediatric ADR reports collected in our city from Jan.2002 to Sept.2007 were statistically analyzed in respect of children's age and sex,route of administration,ADR severity,category of drugs involved,organs or systems involved and clinical manifestations etc.RESULTS: Of the 188 pediatric ADR cases,95(50.5%) were induced by intravenous route.A total of 112 kinds of drugs were involved in the ADR,with anti-infective agents showing the highest proportion.Digestive system,neural system,urinary system and skin etc were involved in the ADR.CONCLUSION: Clinic should attach great importance to the monitoring and reporting of pediatric ADR to reduce or avoid the occurrence of ADR.

Objective To investigate the angiographic coronary atheroslerosis findings with the plasma levels of von Willebrand factor (vWF) and ?-granule membrane protein (GMP-140). Methods 74 patients undergone selectrive coronary angiography (CAG) were divided into 3 groups based on plaque morphology, Group S(n=15), concentric or eccentric stenosis with smooth borders; Group C(n=37), eccentric stenosis with complex borders; Group N (n=22), CAG without coronary atheroslerosis. 37 patients in group C were divided into group Ⅰ (n=10, one-vessel involved CAD), group Ⅱ (n=12, two-vessel involved CAD) and group Ⅲ (n=15, three-vessel involved CAD) based on major epicardial coronary branches lesion. These 37 patients were divided into group x(n=21, ≤3 segments) and group y(n=16,≥4 segments) based on coronry stenotic segments. The plasma levels of vWF and GMP-140 were assayed by ELISA before angiography. Results (1)The plasma levels of vWF and GMP-140 in group C were significantly higher than those in group S(P