Objective To observe the effect of pulmonary surfactant-associated proteins ( Kelisu) combined with ambroxol in the treatment of 180 congenital alveolar dysplasia children with neonatal respiratory distress syndrome ( NRDS) .Methods According to random number table ,180 congenital alveolar dysplasia children with NRDS were randomly divided into the observation group and control group , 90 cases in each group .In addition to conventional therapy,the control group was given ambroxol hydrochloride treatment ,the observation group was given Kelisu on thebasis of treatment of the control group.The treatment effect was compared between the two groups .Results Comparedwith the control group,after treatment the values of PaO2 and pH were significantly increased,PaCO2 significantly decreasedin the observation group(t =5.91,13.16,29.89,2.98,5.11,8.13,all P <0.05).The duration of mechanicalventilation,length of hospital stay were (45.30 ±5.35)h,(10.01 ±2.24)d in the observation group,respectively,which were significantly better than[(68.27 ±6.13)h,(17.24 ±2.39)d]in the control group(t =26.78,20.94,all P <0.05).Conclusion Kelisu combined with hydrochloride ambroxol can significantly improve hypoxia symp -toms in NRDS children,reduce the duration of mechanical ventilation and length of hospital stay ,improve the prognosis.

Objective To explore the curative effect of budesonide combined with terbutaline via atomiza-tion-inhalation in treatment of the acute episode of infantile asthma and its impaction on pulmonary function. Methods 80 children with acute episode of bronchial asthma were randomly divided into observation group and control group. Both groups received comprehensive therapy, moreover, the observation group was treated with aerosol inhalation of budesonide and terbutaline additionally. Results The excellence rate (65% ) and the total effective rate (98% ) of the observation group was significantly higher than those of control group(30% ,75% ) (P <0.05). In control group, there were no significant differences in FEV, and FEV,% between the pre-treatment and post-treatment (P>0.05). In observation group,FEV1 and FEV1% post-treatment were higher than those in pre-treatment(P<0.05). The improvements of FEV, and FEV, % in observation group were significantly higher than those in control group ( P < 0.05 ). Conclusion The treatment of budesonide combined with terbutaline via atomization-inhalation for the acute episode of infantile asthma could improve the clinical efficacy and pulmonary status, which was a safe, quick and effective method for children' s bronchial asthma.

Objective To observe the clinical efficacy of pricking and bleeding the Jing-well points with three-edge needle in treating acute Bell’s palsy.Method Sixty patients with Bell’s palsy were randomized into an observation group and a control group, 30 in each group. In addition to the regular Chinese and Western medicine treatment for Bell’s palsy, the observation group also received pricking and bleeding treatment with three-edge needle at the Jing-well points. The House-Brackman (H-B) Scale and R wave in blink reflex (BR) were observed.Result The total effective rate was 93.0% in the observation group, significantly higher than 90.0% in the control group (P＜0.05). The H-B score significantly increased in both groups after intervention (P＜0.05). The observation group was significantly higher than the control group in comparing H-B score at the end of first and second treatment course (P＜0.05). The R1 and R2 waves in BR increased markedly after intervention in both groups (P＜0.05); the observation group was significantly higher than the control group in comparing R1 wave (P＜0.05), and R2 wave only at the end of the first course (P＜0.05) but not at the end of the second course (P>0.05).Conclusion Combining pricking and bleeding the Jing-well points with three-edge needle in the treatment of Bell’s palsy can enhance the therapeutic efficacy and promote the recovery of the facial nerve function.

Acupuncture Therapy ; Humans ; Male ; Middle Aged ; Ophthalmoplegia ; therapy

Objective To investigate the clinical effectiveness of peripherally inserted central catheters(PICC) and peripheral intravenous catheters(PIV) in tumor chemotherapy. Methods A total of 180 patients with intravenous chemotherapy were randomly divided into two groups. 108 patients in the PICC group, 72 patients in the PIV group. The holding time and complications were observed and compared. Results The rate of complication in the PICC group were much lower than the PIV group, however was much longer than the PIV group in holding time. But there was no statistical difference in the positive culture rate of bacteria of two groups. Conclusions It is very safe to use PICC which can reduce the rate of complication of catheters and venipuncture times and is worthy of spreading in practice.

ObjectiveTo establish a method for the determination of Nuezhenide and Apiganin 7-O-neohesperidoside in Shanxiangyuan tablets.Methods The Luna C1s column was used,the mobile phase consisted of HCN-0.5％H3PO4(41 ∶ 59),the flow rate was 1.0 ml/min,the column temperature was 30℃,the UV detector was set at 336nm.Results The linear response range was 0.016～0.32 mg/ml (r=0.9997) and 0.006～0.11 mg/ml respectively.The average recovery rate was 99.0％ and 97.5％ respectively,RSD was 1.83％ and 1.57％ respectively,ConclusionThe method was simple,accurate and repeatable.It can be applied in quantitative determination of Nuezhenide and Apigenin 7-O-neohesperidoside in Shanxiangyuan tablets.

Objective To compare the effects of two different chemotherapies in treatment acute myeloid leukemia(ALM) patients.Methods sVEGF concentration was measured by ELISA in 32 AML patients.Section one,15 patients,combined with Ara-C,daunorubicin,etoposide and intrathecal Ara-C.Section two,17 patients,consisted of a combination of Ara-C,idarubicin,etoposide,mitoxantrone and intrathecal Ara-C.Results sVEGF level was significantly increased in newly diagnosed AML.The level of sVEGF in AML after 2 cycles of standard chemotherapy was significantly lower than newly diagnosed cases,but the effect of section two was much better compared with section one.Compared with the section one,the complete remission rate of section 2 was 82.4％ (P ＜ 0.05 ).Conclusion sVEGF as a proangiogenesis factor was significantly increased in serum with AML.The level of sVEGF in patients with AML obtained thermotherapy was significantly lower than that of pre-treating AML ones.VEGF should play a very important role in the leukemogenic process.The section two therapy should be used clinically.

Objective To observe treatment efficacy of acupuncture on the acquired paralysls.Methods Clear diagnosis of acquired paralysis patients 105 cases of sexual walleye were selected.Randomly divided into two groups.Therapy unit gave acupuncture therapy.Results Ridit analysis of the two sets of efficacy(P < 0.05) ,significantly better in the treatment group than the control group treatment time is short group(P <0.01).Follow-up six months.No relapse.Conclusion Acupuncture treatment efficacy exact onset of acquired paralysis.

Objective To explore effect of needle pot ombined with acupiont injection on the treatment of stock flank nervi cutanei inflammation. Methods 104 xases of bright stock flank nervi cutanei inflammation wese di-vided into two groups,the treatment group by the needle pot combined with acupoint injection, The control group used the needle pot treatment only. Results After Ridit analysis, the treatment group obviously surpasses the control group ( P<0.05 ), The treatment group self-conscious symptom and the body drafts vanishes the time obviously surpasses the comparison group(P<0.01 ). Along with ouow-up half ayear, recurrent rate is obviously lower than the control group( P<0.01 ). Conclusion The needle pot unifies the acupuncture point injection treatment stock flank nervi cu-tanei inflammation may clearly enhance the curative effect ,reduces the treatment time and recurrenle.

OBJECTIVE: To investigate the effect of propofol on apoptosis in lung tissue of oleic acid-induced acute lung injury(ALI) rats.METHODS: Forty male SD rats were randomly divided into normal control group,ALI group,low,medium and high-dose(4,8,16 mg?kg-1?h-1) propofol groups.Except for the normal control group,the other 4 groups were infused with oleic acid through jugular vein followed by the infusing of the corresponding drugs for 4 h.Then the rats were sacrificed by exsanguination.Lung tissue was immediately sampled for observation of the pathologic change under light microscope and detection of apoptosis and the expression of Fas/FasL,Bax/Bcl-2 in lung tissue by FCM.RESULTS: In ALI group compared with the normal control group,the apoptosis rates in lung tissue cells was markedly increased(P