1.Potentiating CD8
Juanjuan YUAN ; Ting CAI ; Xiaojun ZHENG ; Yangzi REN ; Jingwen QI ; Xiaofei LU ; Huihui CHEN ; Huizhen LIN ; Zijie CHEN ; Mengnan LIU ; Shangwen HE ; Qijun CHEN ; Siyang FENG ; Yingjun WU ; Zhenhai ZHANG ; Yanqing DING ; Wei YANG
Protein & Cell 2021;12(4):240-260
Metabolic regulation has been proven to play a critical role in T cell antitumor immunity. However, cholesterol metabolism as a key component of this regulation remains largely unexplored. Herein, we found that the low-density lipoprotein receptor (LDLR), which has been previously identified as a transporter for cholesterol, plays a pivotal role in regulating CD8
2.Correction to: Potentiating CD8+ T cell antitumor activity by inhibiting PCSK9 to promote LDLR-mediated TCR recycling and signaling.
Juanjuan YUAN ; Ting CAI ; Xiaojun ZHENG ; Yangzi REN ; Jingwen QI ; Xiaofei LU ; Huihui CHEN ; Huizhen LIN ; Zijie CHEN ; Mengnan LIU ; Shangwen HE ; Qijun CHEN ; Siyang FENG ; Yingjun WU ; Zhenhai ZHANG ; Yanqing DING ; Wei YANG
Protein & Cell 2022;13(9):694-700
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