Objective To compare the effect of myomectomy and uterine artery embolization in the treatment of uterine fibroids .Methods 158 patients who were pathologically diagnosed uterine fibroids were randomly divided into the uterine artery embolization group and myomectomy group ,79 cases in each group .The blood loss 3 days after operation,pelvic pain and pressure symptoms ,hospitalization time,follow-up and time of normal activity were recorded and compared.Results The pelvic pain,pressure symptoms,hospitalization time,cure rate,incidence rate of compli-cations and recurrence rate of the two groups had no statistically significant differences ( t=1.21,0.97,1.06,χ2 =0.98,1.21,1.32,all P>0.05).The postoperative bleeding score ,time of return to normal activity in the uterine artery embolization group were (5.8 ±0.5) points,(9.8 ±1.8) d,which were better than those of the myomectomy group[(4.9 ±0.4)points,(25.9 ±5.1)d](t=3.76,5.98,all P<0.05).Conclusion The effect of the myomec-tomy and uterine artery embolization treatment for uterine leiomyoma is similar ,and both have high efficiency and safe-ty,but the uterine artery embolization treatment has less impact on the body of patients .