Objective To compare the efficacy and safety of ivermectin with metronidazole in patients with intestinal acariasis.Methods 24 patients with typical intestinal acariasis were selected and divided into two groups,each group had 12 members.Double-blind,randomized clinical trial of ivermectin versus metronidazole was assigned.Results 24 patients completed 3 courses.The total cure rate of ivermectin and metronidazole were 100%(12/12) and 25%(3/12),respectively.There was statistical difference between the two groups(P

Digital reform serves as powerful driver for high-quality development of hospitals. Taking the problems existing in the decision-making mechanism of major issues as a breakthrough, a tertiary hospital used digital thinking to optimize the decision-making mechanism. The hospital took such means as optimizing the rules of procedure, strengthening the pre-decision assessment, clarifying the principle of " two initiatives" , improving the " No.1 issue" system, strengthening the linkage between the Party committee and meeting the president′s office meeting, and standardizing the supervision and implementation. By such means, the hospital successfully built a smart, efficient, coordinated, and closed-loop operation and management system, desirably strengthening the leadership and core role of the Party committee, enhancing the president′s overall management of business work, as well as improving the decision completion rate and feedback rate.

Objective? To explore the effects of need-based nursing practice in elderly patients with radical resection surgery for rectal cancer. Methods? From 1 February 2017 to 3 May 2018, we selected 80 elderly patients with radical resection for rectal cancer in colon-rectum-anus surgery at the First Affiliated Hospital of Zhengzhou University as subjects by convenience sampling. All of the patients were randomly divided into control group (n=40) and observation group (n=40) with the method of random number table. Control group carried out routine nursing care. Apart from the routine nursing, observation group provided need-based nursing care. We compared the post-operative recovery, scores of pain, anxiety, depression and quality of life as well as satisfaction after intervention among patients between the two groups. Results? The time for the first exhaust, ambulation and the removal of sutures as well as hospital stay in the observation group were shorter than those in the control group with statistical differences (P＜ 0.05). There were statistical differences in the scores of pain, anxiety and depression of patients after surgery between the two groups (P＜ 0.01). After intervention, the scores of pain, vitality, social functioning, emotional function, mental health and general health of quality of life in observation group were higher than those of control group with statistical differences (P＜0.05). After intervention, the patient satisfaction of observation group was higher than that of control group with statistical difference (P＜0.05). Conclusions? Need-based nursing approach can improve the postoperative recovery of elderly rectal cancer patients, alleviate pain, anxiety and depression, reduce the incidence of adverse events, improve the quality of life and satisfaction of patients, hence is worthy of being widely used in clinical practice.

Objective? To investigate the current status and influencing factors of anxiety and depression in rectal cancer patients with permanent intestinal orifice. Methods? By convenience sampling, we selected the rectal cancer patients with permanent intestinal orifice who were admitted to Department of Colorectal and Anal Surgery in the First Affiliated Hospital of Zhengzhou University from January 2016 to December 2018 as our participants in the study. They were investigated by Anxiety Self-Rating Scale and Depression Self-Rating Scale. Totally 165 questionnaires were distributed with 157 valid ones retrieved. Results? In the 157 patients, 74 patients (47.13%) suffered from anxiety: 32 of them had mild anxiety and 42 patients had moderate anxiety. In the 157 patients, 95 (60.51%)of them suffered from depression:54 patients had mild depression, 36 patients had moderate depression and 5 patients had severe depression. Patients who were females, working staff, have low income, impaired ability of self-care, have not received the preoperative education, or have postoperative complications tend to develop anxiety and depression(P＜0.05). Conclusions? There is a higher proportion of rectal cancer patients with permanent intestinal orifice who had anxiety and depression. The influencing factors are various and complex,and targeted intervention has positive significance in improving the patients＇ negative mood.

Objective: To explore the application effect of secondary personalized chairside education on changing the knowledge and behavior of patients with oral periodontal disease. Methods: A total of 124 patients experiencing initial periodontal disease were selected. Sixty-two patients were observed in the observation group, and 62 patients were observed in the control group. After the doctor checked and determined the periodontal condition of the patients, the nurse conducted a targeted, personalized secondary one-on-one chairside mission for the observation group; in the control group, the nurses provided routine one-to-one health education to the patients before treatment. Statistical analysis was conducted to assess periodontal knowledge mastery, self-care behaviors, rate of return for periodontal treatment and patient satisfaction after 3 months. The plaque index and scale index were statistically analyzed before and 3 months after treatment. Results : No statistical difference was found in the general data between the two groups of patients (P > 0.05); however, the degree of mastery of periodontal knowledge in the observation group was higher than that in the control group. The degrees of mastery of the clinical manifestations, hazards and treatment methods were 96.7%, 93.5%, and 91.9% in the observation group and 72.5%, 48.3%, and 69.3% in the control group, respectively; the difference was statistically significant (P < 0.05). The patients in the observation group were more likely than those in the control group to brush more than 2 times daily, use dental floss and use an interdental brush; 100%, 96.7%, and 77.4% of patients in the observation group and 80.6%, 56.4%, and 40.3% of patients in the control group participated in these oral health care behaviors, respectively. The difference was statistically significant (P < 0.05). The rate of recovery and patient satisfaction were higher in the observation group than in control group at 3 months; the rate of recovery and patient satisfaction were 80.6% and 96%, in the observation group and 41.9% and 88.7% in the control group, respectively. The difference was statistically significant (P < 0.05). After 3 months, the plaque index in the observation group was lower than that in the control group (1.71 ± 1.12, 2.35 ± 0.78), and the difference was statistically significant (P < 0.05). Conclusion Secondary personalized chairside education can significantly improve the patient’s cognition of the disease, allow the formation of accurate oral health awareness, and change the patient’s bad oral hygiene habits and medical behavior. Thus, this method is an effective oral health education method and can change the knowledge and beliefs of patients with oral periodontitis.