Objective:To observe and compare the clinical effect of single-incision and two-incision posterior chamber phakic intraocularlens implantation in the correction of extreme myopia.Methods:40 cases(80 eyes) of patients with extreme myopia underwent conventional two-incision posterior chamber phakic intraocularlens implantation in our hospital from January 2011 to June 2013 were selected as the control group and 40 cases(80 eyes) underwent single-incision posterior chamber phakic intraocularlens implantation from July 2013 to January 2016 were selected as observation group.The open hole before and after operation,best corrected visual acuity of vision,operation safety,effectiveness index,diopter (column mirror,equivalent ball for eyeglasses),intraocular pressure,ECD,anterior chamber depth and occurrence of complications were compared between two groups.Results:The uncorrected visual acuity (UCVA) of both groups at 6 months after operation were significantly higher than those before operation (P＜0.05),which was significantly higher in the observation group than that of the control group (P＜0.05);The operation safety and effectiveness index of observation group were significantly higher than those of the control group (P＜0.05);The cylinder and spherical equivalent degree of both groups at 6 months after operation were significantly better than those before operation(P＜0.05),which was significantly better in the observation group than that of the control group(P＜0.05).The corneal endothelial cell counts(ECL) of control group after operation was significantly lower than that before operation (P＜0.05),and no significant difference was found in the ECL of observation group before and after operation (P＞0.05).The ECL of observation group after operation was significantly higher than that of the control group (P＜0.05);The incidence rate of complication in observation group was significantly lower than that of the control group (P＜0.05).Conclusion:Compared with two-incision operation,the single-incision posterior chamber phakic intraocularlens implantation had remarkable clinical effect in the correction of extreme myopia with higher security.

The structure, application and the development foregrounds of mobile water producing system are introduced, and the domestic and international development of water producing system is looked back as well as the clinical situation of mobile water producing system. Furthermore, the merits and defects of mobile water producing system are introduced. Mobile water producing system provides an effective guarantee for settling clinical emergency or bed-side blood purification treatment, and it has vast development foreground.

Objective To investigate the relation of angiopoietin-1 (Ang-1) with prognoses of patients with acute ischemic stroke.Methods Eighty-nine patients with acute ischemic stroke,admitted to our hospitals fiom October 2015 to December 2017,were chosen.The patients were diagnosed as having acute ischemic stroke by digital subtraction angiography (DSA),and assessed with National Institute of Health Stroke Scale (NIHSS) on the time of admission and 21st d of admission;modified Rankin Scale (mRS) was performed on 90th d of admission.According to NIHSS and mRS scores,these patients were divided into a good prognosis group (difference value of NIHSS scores＞0,mRS scores≤ 2) and a poor prognosis group (difference value ofNIHSS scores≤ 0,mRS scores＞2).In addition,31 patients without acute ischemic stroke who were randomly selected as a control group at the same time.The clinical data of all study subjects were collected.Morning fasting blood of the patients was collected on 2nd,7th,14th,and 21st d of admission.The serum Ang-1 expression was detected by ELISA.Results (1) Fifty-seven patients were into the good prognosis group and 32 were into the poor prognosis group;there were no significant differences in age,gender,hypertension history,diabetes history,smoking history,and drinking history among the control group,good prognosis group and poor prognosis group (P＞0.05).(2) There was no statistically significant difference in Ang-1 expression level in control group among different time points (P＞0.05);however,Ang-1 level in the good prognosis group and the poor prognosis group was the highest on 2n d of admission,and then,gradually decreased,and it still had high expression on the 21st d;significant differences were noted among the 3 groups on 2nd,7th,14th,and 21st d of admission (P＜0.05),and Ang-1 level in the good prognosis group was significantly higher than that in the poor prognosis group and control group (P＜0.05).Conclusion Ang-1 level increases in patients with acute ischemic stroke;Ang-1 level in good prognosis patients is higher than that in poor prognosis patients,suggesting that Ang-1 may be related to their prognoses.