Objective To investigate the relationship between metabolic syndrome and related factors and recurrence of ischemic stroke.Methods 90 in-and out-patients with ischemic stroke in Jiangbei District Hospital of Traditional Chinese Medicine during May 2013 and May 2014 were enrolled.In 90 cases,4 patients with cerebral hemorrhage were excluded.Basic data of the 86 patients were investigated,which including gender,age,abdominal circumference,smoking,drinking,family history of stroke,diabetes,hypertension,hyperlipidemia,a history of atrial fibrillation,transient ischemic attacks,fasting blood glucose,triglyceride,cholesterol,uric acid,homocysteine,urinary protein-creatine ratio,carotid ultrasound examination.We investigated patients with or without recurrent stroke during one year of telephone visit and follow-up.Patients with recurrent stroke were investigated.Results During the one year follow-up,24 cases in the 86 patients with ischimic stroke were recurrent,the recurrence rate was 27.9 ％.2 cases in the recurrent patients died because of massive cerebral infarction,accounted for 8.3％ of the patients with recurrent stroke.According to Chi-square test,smoking,high fasting plasma blood glucose,hypertension,elevated low density lipoprotein cholesterol,high uric acid,high homocysteine and carotid atherosclerosis all had correlation with recurrent stroke(P＜0.05).In this logistic-regression model,smoking,high fasting plasma blood glucose,hypertension,elevated low density lipoprotein cholesterol,high uric acid,high homocysteine and carotid atherosclerosis were all predictors for recurrence of ischemic stroke.Conclusion Cntrolling the risk factors after the first stroke as a long term strategy has important clinical significance for secondary prevention of ischemic stroke.

The amplitude integrated electroencephalogram is a simplified form of electroencephalogram,which can monitor electroencephalogram background activity and analyze the figures' continuity,cycling,the amplitude of the lower border and bandwidth,evaluate the preterm infants' brain maturity prognosis.It has the advantages of simple operation,intuitive figure,small interference and other features.It is an important noninvasive assessment of functional state of the brain cortex in recent years.This paper reviews the amplitude integrated EEG principle,pattern analysis,clinical application of brain function monitoring in preterm infants.

Medical culture,a sinneseinheiten of infinitely complex facts,phenomena and subjective information in the field of medicine,is characterized by subjectivity,objectivity and complexity.As an important component of modern medical education,medical culture has always been a research problem in the field of culture.In view of this,mastering scientific research principles and approaches plays a vital role in medical culture researches.This paper tries to discuss the research methods of medical culture combined positivism and humanism,in order to provide valuable theoretical support for medical culture research.

In This paper, the advances of clinical research and application of the drugs for preventing and treating bronchial asthma were reviewed, with a detailed reference to such drugs as β2-adrenoceptor agonist, theophylline, anticholinergic drugs, glucocorticoids, mast cell membrane stabilizers, antihistamines, leukotriene receptor antogonists, new anti-inflammatory drugs and immunosuppressive drugs as well as immunotherapy.

ObjectiveTo study The clinical value of routine ultrasound and trans-rectal ultrasound in diagnosis of bladder cancer. Methods87 patients with bladder cancer were diagnosed by routine ultrasound and transrectal ultrasound,and compared with individual ultrasound examination about the rate of display and accuracy. ResultsIn comparison with individual ultrasound examination, the rate of display and accuracy were obviously improved by routine ultrasound and trans-rectal ultrasound,there was statistical significance. ConclusionThe routine ultrasound and trans-rectal ultrasound had the practical value in diagnosis of bladder cancer.

The isolation, purification and identification of liver-specific membrane lipo-protein (LSP) is briefly presented. Human fetal liver was homogenized and submitted to 105,000 g for 1 hour. The supernatent was detected with presence of LSP. It was then fractioned by chromatography through Sephadex G-100 and Sephadex G-200. LSP revealed in the first peak.Nine rabbits of both sexes, weighing about 3 kg, were immunized with LSP to prepare antiserum. 80 sera of various liver disease patients were detected. Evidence of an immune response to the LSP was present in 18 of 23 cases (78.2%) of chronic active hepatitis. This observation suggests that the LSP may play an important role in the pathogenesis of liver injury.

An experiment of treatment for acute hepatic necrosis with glucagon, insulin branched chain aminoacid and scopolamine in rats was reported.Liver specimens were investigated microscpically and a serial changes of 3H-TdR were evaluated.It is suggested that G-I therapy may reduce the hepatic injury and may also accelerate the regeneration of hepatic cells in D-gal-induced hepatic injiury.G-I thfrapy may be effective for prevention of progressing hepatic necrosis and promotion of hepatic regeneration in fulminant hepatic failure.

Objective To investigate the value of coronary angiography in the diagnosis of coronary heart disease in clinical applications .Methods In our hospital from June 2011 to June 2013,between the clinical manifes-tations of 108 cases diagnosed coronary heart disease patients in this study .All patients were resting ECG ,Holter mo-nitoring,echocardiography and coronary angiography inspection ,combined with relevant literature,research coronary artery disease gold standard-coronary angiography application value .Results 108 cases of subjects ,coronary angi-ography in the diagnosis of coronary heart disease in 74 cases,the positive rate of 68.5%;resting ECG,Holter monito-ring and echocardiography compared with coronary angiography were significantly different (χ2 =84.43, 6.37, 163.55,all P <0.05 ).Single-vessel disease in 19 cases no significant coronary stenosis ( stenosis <50%) or normal,according to echocardiography ,ECG,and family history of or risk factors such as hypertension ,coronary heart disease in clinical diagnosis made .Conclusion Coronary angiography of coronary heart disease diagnosis can be used as the most important means of minimally invasive and non-invasive examination methods ,which has high de-tection rate of coronary heart disease and significantly improved accuracy ,and clear coronary lesion location ,extent.So it should be used as crown heart disease diagnosis conventional methods .

Arsenic trioxide (As2O3)is the main component of traditional Chinese medicine arsenic,which was initially used in the treatment of blood system diseases.In recent years,studies have found that it also has a good effect on a variety of solid tumors,especially gastric cancer.It has been confirmed that As2O3 can inhibit proliferation and metastasis of gastric cancer cells,induce apoptosis and protective autophagy,inhibite lymphatic formation and angiogenesis,affect the expression of telomere-related proteins in gastric cancer cells.

The FOXO gene, which is a member of the Forkhead box (Fox) gene family, is found in drosophila and is widespread in the eukaryotes of many organisms, including yeast and mammals. This gene transcripts the FOXO protein family, which has impor-tant roles in metabolism, cellular proliferation, stress resistance, and apoptosis. Activation of cell survival pathways, such as phos-phoinositide-3-kinase/AKT or RAS/mitogen-activated protein kinase, phosphorylates FOXOs at different sites, thus regulating the nu-clear localization or degradation of FOXOs. A growing number of evidence indicates that FOXO acts as a tumor suppressor in a wide variety of tumors. Scientists have focused on the correlation between tumors and FOXO. In combination with other chemo-or radiother-apy treatments, drugs designed to increase or restore FOXO activity may constitute a potential strategy in cancer treatment. This review summarizes details on the regulation of FOXO and the latest research progress of FOXO as a molecule therapeutic target.