Objective: To study the effect of fish-oil fatty emulsion on immunity of post-operation patients with malignancy tumors.Methods: Forty-three post-operation patients with malignancy tumors were randomly divided into control group and study group and both groups were provided with parenteral nutrition treatment [104.6 kJ(25 kcal/kg)].Fish-oil fatty emulsion was given to the study group.The level of serum albumin,immunity function,jaundice index,aminotransferase,blood lipid and morbidity rate of infectious complications of the two groups were compared.Results: After five days of post-operation treatment,in the study group,the immunity function was significantly improved and morbidity rate of infectious complications declined.The levels of serum albumin,the blood lipid,jaundice index,and aminotransferase had no significant difference between the two groups.Conclution:Fish-oil fatty emulsion is beneficial to the immunity function and can emilsion decrease infectious complications of post-operation patients with malignancy tumors.

Citrin deficiency,caused by mutations in SLC25A13,is an autosomal recessive genetic disorder with two age-related phenotypes:adult-oneset type Ⅱ citrullinemia and neonatal intrahepatic cholestasis.Recently,it has been found mostly in individuals of East Asian ancestry.In south China,there is a high mutation carrier frequency especially.There is still a lack of criteria for clinical or biochemical diagnosis of this disease,gene analysis is the main basis of the current diagnosis consequently.Surging number of case reports indicate that Citrin deficiency is not a self-limited disease.Early diagnosis and proper treatments may improve the prognosis.This paper focuses on the current researches in order to make further comprehensiom.

Objective To observe the clinical curative effect of Xuezhikang maintaining treatment for senile hyperlipidemia.Methods According to the digital table,96 elderly patients with hyperlipidemia were selected and randomly divided into the three groups.The control group 1 with 32 cases took orally rosuvastatin before sleeping 10mg per time,1 time /day,12 weeks one treatment course.The control group 2 with 32 cases took orally Xuezhikang capsule before sleeping 0.6g 2 times/day,12 weeks one treatment course.The treatment group with 32 cases took first orally rosuvastatin before sleeping 10 mg/time,1 time /day for 4 weeks,then changed to use Xuezhikang capsule 0.6g 2 times/day for six weeks.The total treatment course was 12 weeks.Results After treatment,TC,TG,LDL-C in three groups all declined significantly and HDL-C increased.The curative effect was similar in treatment group and control group 1 with no statistical difference(P >0.05).Conclusion Xuezhikang has similar efficacy with rosuvastatin 10 mg/time in hyperlipidemia,and recommand Xuezhikang clinical use for its lower price.

This article introduces concept of quality of work life and analyses main factors influencing quality of teachers'work life. In order to stabilize emotion of teachers and retain excellent teachers,we put forward the suggestions for improving and enhancing the quality of teachers'work life.

Objective To evaluate the long-term effectiveness of different-dose of botulinum toxin A (BTXA) therapy on axillary hyperhidrosis.Methods Total 86 patients with axillary hyperhidrosis were self-controlled.One group of left axillary was injected with a low-dose of BTXA,50U.Another group of right axillary was injected with a high-dose of BTXA.A total dose of 200 U of BTXA was used per axilla.Patients were followed-up for 29 months.To investigate the effect of two methods,we analyzed two ranked data by rank sum test and x2 test to judge the disparities of the therapeutic effect.Results The results showed that the relapse-free interval of two groups with axillary hyperhidrosis was significant difference through the statistical analysis (P ＜ 0.05).Conclusions High-dose of BTXA treatment is capable of prolonging the antihidrotic effect on axillary hyperhidrosis.

During the whole process of rescue operations,the teleconsultation vehicle has not only realized long-range consultation function but also played a vital important role in emergency communication,propagation,contaction,etc.Its manifestation tracks out some practical methods for the emergency rescue operation hereafter.

To meet with the new problems of curriculum design about prevention medicine field to undergraduate in medical college,based on our teaching practice,we tried to explore some teaching measures about fieldwork of health education,in term of updating teaching methods and skills so as to enhance our students' integrated quality,cultivate and bring up more and more capable new-pattern preventive medical students fit for the public requirements.

OBJECTIVE:To establish a HPLC method for the determination of dolastron mesylate.METHODS:The sample was separated on Diamonsil C18 column.The mobile phase consisted of acetonitrile-water-1mol? L-1 ammonium formate(450∶ 440∶ 110)(pH=8.0 adjusted with trithylamine)with a flow rate of 1.0mL? min-1.The UV detection wavelength was set at 285nm and the sample size was 20? L.RESULTS:The linear range of dolasetron mesylate was 24～ 56? g? min-1(r=0.999 6),with average recovery at 99.7%(RSD=0.74%).CONCLUSION:The established is simple,sensitive and reproducible,and suitable for the quality control of dolasetron mesylate.

Objective To investigate the effects of Wuling Powder on insulin resistance of C57BL/6J mice induced by high lipid diet, and discuss the mechanism. Methods C57BL/6J mice were randomly divided into six groups:normal group, model group, rosiglitazone group, Wuling Powder in low, middle, and high dose groups, 10 mice per group. Besides the normal group, other five groups were fed with high fat and sugar diet, with a purpose to establish insulin resistance model. Normal group and model group were given pure water. Rosiglitazone group received a gavage with rosiglitazone of 0.75 mg/kg. Wuling Power low, middle, and high groups received gavage with Wuling Power of 1.23, 3.69, 11.07 g/kg, respectively, the does volume was 0.2 mL/10 g, once a day. The weight and abdominal girth were detected every week. At the end of the sixth week, mice were given 12-hour fasting, and their eyeball were taken for blood. The body weight, length, and fat in abdomen and both kidneys were detected. Paraffin section was made with HE staining. FPG and FINS of each group were detected. ISI and IRI were calculated, and TC and TG were detected. Results Compared with the model group, Wuling Powder can significantly reduce the body weight and abdominal girth of mice (P<0.01, P<0.001), improve liver fatty degeneration, lower the FPG, FINS, TCH, TG, IRI, and increase the ISI in mice (P<0.05, P<0.01). Conclusions Wuling Powder has the effect of preventing insulin resistance of C57BL/6J mice induced by high lipid diet.

Objective: To study the effects of vitamin C and basic fibroblast growth factor (bFGF) on proliferation in vitro and transplantation in vivo of bone marrow mesenchymal stem cells (BMSCs) in rats with cerebral infarction. Methods: Circled digit oneBMSCs of rats were isolated by using density gradient centrifugation and adherent method. The rats were divided into four groups according to the different growth factors added in the medium: control group, Vc group (50 μg/mL), bFGF group (1 μg/L), and Vc + bFGF group (50 μg/mL Vc and 1 μg/L bFGF). The cellular morphology in each group was observed. MTT colorimetric method was used to detect the absorbance (A value) at the wavelength of 450 nm at day 1, 2, 3, 5, and 7 after the culture; flow cytometer was used to detect the cell cycle cultured after 96 hours. Circled digit twoA model of right middle cerebral artery occlusion (MCAO) for 2 hours was induced by the suture method in 20 rats, and they were randomly divided into 2 groups: the BMSC transplantation group cultured by the combined Vc + bFGF and the control BMSC transplantation group. BMSCs in the corresponding groups were transplanted in rats 24 hours after cerebral infarction. At 1, 2, and 3 weeks after transplantation, the brain tissue slices of the rats were prepared, and they were revealed by BrdU immunohistochemistry staining. Results: Circled digit oneMorphological observation showed that the proliferation of BMSCs was most fast in the Vc + bFGF group, and it was relatively slow in the control group. Circled digit twoThe A value of cells in each group began to increase at day 2 after the culture. It reached the peak at day 3 in the Vc group and bFGF groups (F = 728.52 and F = 197.18, P < 0.05); it reached the peak at day 5 in the Vc + bFGF group (F = 1771.32, P < 0.05), and then both deceased at day 7. From the second day, the A value in the bFG, Vc and Vc + bFGF groups was significantly higher than that in the control group; from the third day, Vc + bFGF group was higher than the Vc and bFGF group, and there was significant difference (P < 0.05). Circled digit threeThe percentage of cells in the proliferative phase (S + G2 + M) in the Vc, bFG and Vc + bFGF groups was higher than that in the control group, and there was significant difference (P < 0.05). Circled digit fourTwo weeks after the BMSC transplantation, BrdU-positive cell counts in the brain tissue slices in the BMSC transplantation group cultured by the combined Vc + bFGF was higher than that in the control BMSC transplantation group; the positive cell counts in both groups decreased at week 3, however, the former was still higher than the latter, and there was significant difference (P < 0.01). Most BrdU labeled BMSCs appeared in the centre or around the infarct brain. Conclusion: Both Vc and bFGF may promote proliferation of BMSCs in rats. The efficacy of the combination of both is better than any one alone. Survival ability of the BMSCs are obviously strengthened when they are transplanted into rats infarcted brain.