1.Effect of metabolic syndrome and related factors on recurrence of ischemic stroke
Chongqing Medicine 2017;46(11):1484-1486
Objective To investigate the relationship between metabolic syndrome and related factors and recurrence of ischemic stroke.Methods 90 in-and out-patients with ischemic stroke in Jiangbei District Hospital of Traditional Chinese Medicine during May 2013 and May 2014 were enrolled.In 90 cases,4 patients with cerebral hemorrhage were excluded.Basic data of the 86 patients were investigated,which including gender,age,abdominal circumference,smoking,drinking,family history of stroke,diabetes,hypertension,hyperlipidemia,a history of atrial fibrillation,transient ischemic attacks,fasting blood glucose,triglyceride,cholesterol,uric acid,homocysteine,urinary protein-creatine ratio,carotid ultrasound examination.We investigated patients with or without recurrent stroke during one year of telephone visit and follow-up.Patients with recurrent stroke were investigated.Results During the one year follow-up,24 cases in the 86 patients with ischimic stroke were recurrent,the recurrence rate was 27.9 %.2 cases in the recurrent patients died because of massive cerebral infarction,accounted for 8.3% of the patients with recurrent stroke.According to Chi-square test,smoking,high fasting plasma blood glucose,hypertension,elevated low density lipoprotein cholesterol,high uric acid,high homocysteine and carotid atherosclerosis all had correlation with recurrent stroke(P<0.05).In this logistic-regression model,smoking,high fasting plasma blood glucose,hypertension,elevated low density lipoprotein cholesterol,high uric acid,high homocysteine and carotid atherosclerosis were all predictors for recurrence of ischemic stroke.Conclusion Cntrolling the risk factors after the first stroke as a long term strategy has important clinical significance for secondary prevention of ischemic stroke.
2.The amplitude integrated electroencephalogram in application of preterm infants in brain function monitoring
International Journal of Pediatrics 2012;39(2):166-169
The amplitude integrated electroencephalogram is a simplified form of electroencephalogram,which can monitor electroencephalogram background activity and analyze the figures' continuity,cycling,the amplitude of the lower border and bandwidth,evaluate the preterm infants' brain maturity prognosis.It has the advantages of simple operation,intuitive figure,small interference and other features.It is an important noninvasive assessment of functional state of the brain cortex in recent years.This paper reviews the amplitude integrated EEG principle,pattern analysis,clinical application of brain function monitoring in preterm infants.
3.The clinical value of routine ultrasound and trans-rectal ultrasound in diagnosis of bladder cancer
Chinese Journal of Primary Medicine and Pharmacy 2011;18(15):2041-2042
ObjectiveTo study The clinical value of routine ultrasound and trans-rectal ultrasound in diagnosis of bladder cancer. Methods87 patients with bladder cancer were diagnosed by routine ultrasound and transrectal ultrasound,and compared with individual ultrasound examination about the rate of display and accuracy. ResultsIn comparison with individual ultrasound examination, the rate of display and accuracy were obviously improved by routine ultrasound and trans-rectal ultrasound,there was statistical significance. ConclusionThe routine ultrasound and trans-rectal ultrasound had the practical value in diagnosis of bladder cancer.
4.PRELIMINARY OBSERVATION ON THE EXPERIMENTAL TREATMENT FOR ACUTE HEPATIC NECROSIS WITH GLUCAGON AND INSULIN
Academic Journal of Second Military Medical University 1982;0(01):-
An experiment of treatment for acute hepatic necrosis with glucagon, insulin branched chain aminoacid and scopolamine in rats was reported.Liver specimens were investigated microscpically and a serial changes of 3H-TdR were evaluated.It is suggested that G-I therapy may reduce the hepatic injury and may also accelerate the regeneration of hepatic cells in D-gal-induced hepatic injiury.G-I thfrapy may be effective for prevention of progressing hepatic necrosis and promotion of hepatic regeneration in fulminant hepatic failure.
5.The value of coronary angiography in the diagnosis of coronary heart disease
Chinese Journal of Primary Medicine and Pharmacy 2014;(7):1021-1023
Objective To investigate the value of coronary angiography in the diagnosis of coronary heart disease in clinical applications .Methods In our hospital from June 2011 to June 2013,between the clinical manifes-tations of 108 cases diagnosed coronary heart disease patients in this study .All patients were resting ECG ,Holter mo-nitoring,echocardiography and coronary angiography inspection ,combined with relevant literature,research coronary artery disease gold standard-coronary angiography application value .Results 108 cases of subjects ,coronary angi-ography in the diagnosis of coronary heart disease in 74 cases,the positive rate of 68.5%;resting ECG,Holter monito-ring and echocardiography compared with coronary angiography were significantly different (χ2 =84.43, 6.37, 163.55,all P <0.05 ).Single-vessel disease in 19 cases no significant coronary stenosis ( stenosis <50%) or normal,according to echocardiography ,ECG,and family history of or risk factors such as hypertension ,coronary heart disease in clinical diagnosis made .Conclusion Coronary angiography of coronary heart disease diagnosis can be used as the most important means of minimally invasive and non-invasive examination methods ,which has high de-tection rate of coronary heart disease and significantly improved accuracy ,and clear coronary lesion location ,extent.So it should be used as crown heart disease diagnosis conventional methods .
6.Discussion on the Research Methods of Modern Medical Culture Based on Positivism and Humanism
Chinese Medical Ethics 2017;30(2):249-251
Medical culture,a sinneseinheiten of infinitely complex facts,phenomena and subjective information in the field of medicine,is characterized by subjectivity,objectivity and complexity.As an important component of modern medical education,medical culture has always been a research problem in the field of culture.In view of this,mastering scientific research principles and approaches plays a vital role in medical culture researches.This paper tries to discuss the research methods of medical culture combined positivism and humanism,in order to provide valuable theoretical support for medical culture research.
7.The Advances of Clinical Research and Application of Drugs for Prevention and Treatment of Bronchial Asthma
Herald of Medicine 2001;(1):18-19
In This paper, the advances of clinical research and application of the drugs for preventing and treating bronchial asthma were reviewed, with a detailed reference to such drugs as β2-adrenoceptor agonist, theophylline, anticholinergic drugs, glucocorticoids, mast cell membrane stabilizers, antihistamines, leukotriene receptor antogonists, new anti-inflammatory drugs and immunosuppressive drugs as well as immunotherapy.
8.STUDIES ON LABORATORY AND CLINICAL SIGNIFICANCES OF THE LIVER SPECIFIC MEMBRANE LIPOPROTEIN IN LIVER DISEASESrWITH PRELIMINARY ANALYSIS OF 80 CASES
Academic Journal of Second Military Medical University 1981;0(03):-
The isolation, purification and identification of liver-specific membrane lipo-protein (LSP) is briefly presented. Human fetal liver was homogenized and submitted to 105,000 g for 1 hour. The supernatent was detected with presence of LSP. It was then fractioned by chromatography through Sephadex G-100 and Sephadex G-200. LSP revealed in the first peak.Nine rabbits of both sexes, weighing about 3 kg, were immunized with LSP to prepare antiserum. 80 sera of various liver disease patients were detected. Evidence of an immune response to the LSP was present in 18 of 23 cases (78.2%) of chronic active hepatitis. This observation suggests that the LSP may play an important role in the pathogenesis of liver injury.
9.Application of arsenic trioxide in gastric cancer treatment
Journal of International Oncology 2013;(6):460-462
Arsenic trioxide (As2O3)is the main component of traditional Chinese medicine arsenic,which was initially used in the treatment of blood system diseases.In recent years,studies have found that it also has a good effect on a variety of solid tumors,especially gastric cancer.It has been confirmed that As2O3 can inhibit proliferation and metastasis of gastric cancer cells,induce apoptosis and protective autophagy,inhibite lymphatic formation and angiogenesis,affect the expression of telomere-related proteins in gastric cancer cells.
10.Application of propranolol in women with hyperthyroidism during pregnancy and lactation
Chinese Journal of Endocrinology and Metabolism 2010;26(10):907-909
Physicians often encounter patients with both hyperthyroidism and pregnancy in clinical practice. Proper treatment will help a lot for both mother and fetus. However, whether propranolol could be applied routinely in the medical therapy other than antithyroid drugs is not regularly mentioned in text book, because there were few literatures reporting its side effects including miscarrage, intrauterine growth retardation, bradycardia, respiratory depression, hypoglycemia, and hyperbilirubinemia. Animal experiments revealed bradycardia after propranolol administration, and respiratory depression after birth due to blockage of β receptors in the lungs. Nevertheless, this drug has been considered safe in pregnant hyperthyroid women according to long-term experience, as no malformation has been demonstrated in the offsprings, and it helps a lot in hyperemesis gravidarum as well. Specialists also recommend short-term use like a few weeks before antithyroid drugs set in action and during thyroid storm, in order to avoid potential side effects. It is suggested that less than routine-dose of the drug be administered before labor, as the plasma drug concentration in the neonate would elevate after birth. As for lactating mother, it's safe to take regular dose of the drug because only extremely low dose will be taken by the neonate through milk.