1.Analysis and thinking in an examinaton of diagnostics teaching
Yujiao CAI ; Hua YANG ; Guowei WANG
Chinese Journal of Medical Education Research 2011;10(6):714-715
An analysis of the results of examination of diagnostics teaching in the middle of the semester of 2008 grade is made to discuss the pnoblems existing in teaching and learning so as to improve the teaching quality.
2.Comparison of Therapeutic Efficacy and Safety of Budesonide or Beclometasone Combined with Terbutaline in the Treatment of Acute Attack of Mild and Moderate Asthma in Children
Qinwu CAI ; Zijiang YANG ; Changle WANG
China Pharmacy 2017;28(24):3368-3371
OBJECTIVE:To compare therapeutic efficacy and safety of budesonide or beclometasone combined with terbutanline in the treatment of acute attack of mild and moderate asthma in children.METHODS:A total of 110 children with mild and moderate asthma were randomly divided into group A (55 cases) and group B (55 cases).Based on routine treatment,group A was given Terbutaline sulphate solution for nebulization 1 mL,nebulization inhalation,twice a day+Budesonide suspension for inhalation 2 mL,nebulization inhalation,twice a day.Group B was given Terbutaline sulphate solution for nebulization (same usage and dosage as group A)+Beclomethasone dipropionate suspension for inhalation 2 mL,nebulization inhalation,twice a day.Treatment courses of 2 groups lasted for 7 d.Clinical efficacies,symptoms and signs disappearance time,hospitalization time,asthma relief rate as well as symptoms and signs scores,peak value expiration velocity of flow (PEF),the occurrence of ADR were observed in 2 groups.RESULTS:There was no statistical significance in total response rate,symptoms and signs disappearance time,hospitalization time,asthma relief rate or the incidence of ADR between 2 groups (P>0.05).After treatment,symptoms and signs scores of 2 groups were significantly lower than before,while the PEF were significantly higher than before,with statistical significance (P<0.05),but there was no statistical significance between 2 groups (P>0.05).CONCLUSIONS:Based on routine treatment,budesonide or beclometasone combined with terbutaline sulphate can be used for acute attack of mild and moderate asthma in children.They are similar to each other in therapeutic efficacy and safety.
3.Study on HPLC fingerprint of Pollen Typhae
Ying YANG ; Shiqiang WANG ; Guangxian CAI
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(05):-
bjective:To study and establish the fingerprint of Pollen Typhae.Methods:Hypersil BDS C18(5?m,4.6mm?250mm) chromatographic column mobile phase acetonitrile-0.1 % phosphoric acid solution(10:90)with fiow rate of 1.0 ml/min and UV detector at 254 nm.ResultsTaking Isorhamnetin-3-O-neohesperidoside as the reference peak,11 common peaks were selected as the fingerprint peaks of Pollen Typhae,Technology investigation indicated that the analytical method this study established has desirable precision,reproducibility,and stability.The similarity of Pollen Typhae fingerprints from different batches is better.Conclusion HPLC fingerprint analysis can be a method for quality control of medical material of Pollen Typhae.
4.Placement of pedicle screws undex X-ray fluoroscopy step by step in cadaveric thoracolumbar spine
Genlin WANG ; Huilin YANG ; Xin CAI
Orthopedic Journal of China 2006;0(13):-
[Objective]To investigate the feasibility of the placement of pedicle screws in the thoracolumbar vertebrae under X-ray fluoroscopy step by step.[Method]Eight human cadaveric thoracolumbar spines(T9~L5) were selected and classified into group A and group B randomly,each having 4 specimens.Pedicle screws in group A were placed under X-ray fluoroscopy step by step.CT scanned the specimens of group A and measured the half pedicle length,full pedicle length and the pedicle screw passage length.The "e" angle and "f" angle of pedicle were measured on CT images.When the guide wire was pricked to the half of pedicle length,the wire tip was located at the middle line of the pedicle projection in the standard posterior-anterior image.When the wire was pricked to the full pedicle length in lumbar vertebrae,its tip was located at 3/4 line of the pedicle projection in the standard posterior-anterior image.When the wire was pricked to the full pedicle length in thoracic vertebrae,its tip was located at between 1/2 line and 3/4 line of the pedicle projection.When the wire was pricked into vertebrae,the depth of the wire and the "e" angle were noted in standard lateral image.Pedicle screws were placed by the track of the guide wire.Pedicle screws in group B were placed by traditional technique.The accuracy and feasibility of the method under X-ray fluoroscopy step by step were evaluated by observation of the position of the pedicle screws in group A and group B.[Result] Four of 72(5.56%) pedicle screws were found to have perforated the pedicle wall in group A,and 19 of 72(26.38%) pedicle screws perforated the pedicle wall in group B.The result of group A was superior to that of group B(P
5.Applications of conducting polymers to medical engineering
Yang SHAO ; Xiang WANG ; Shaoxi CAI
Chinese Medical Equipment Journal 1993;0(06):-
Conducting polymers play important roles in tissue engineering and biomaterials. This paper introduces their syntheses and applications to medical engineering.
6.The role of apoptosis in the stress-related changes of intestinal mucosa barrier following traumatic brain injury
Yanbin WANG ; Zhaoxu YANG ; Lei CAI
Chinese Journal of Internal Medicine 2010;49(10):869-872
Objective To investigate the role of epithelial cell apoptosis in the stress-related changes of intestinal mucosa barrier following traumatic brain injury. Methods Sixty-four health male Wistar rats were divided randomly into two groups: (1) traumatic brain injury model group (n =32) ,in which rats suffered from traumatic brain injury by Feeney's method; (2) control group ( n = 32) , rats suffered from sham operation. Each group were divided into four subgroups according 6 h, 12 h,24 h, and 48 h after operation ( n = 8, for each subgroup ). Ileum tissue were taken to observed the damage of the intestinal mucosa under microscope and electronmicroscope. The early apoptosis rate of intestinal mucosal cells were analyzed with Annexin Ⅴ-PI double stained and detected by flow cytometry. Results The intestinal mucosa were damaged and the intercellular space of intestinal mucosal were found increased in traumatic brain injury group. The early apoptosis rate of intestinal mucosal epithelial cells was significant increased in traumatic brain injury group than that in control group [6 h: (13.5 ±3.7)% vs (6.1 ± 1.7)%, P<0.05; 12 h:(66.1±6.0)% vs (5.2±1.1)%, P<0.05; 24 h:(39.8±4.8)% vs (8.4±2.6)%, P<0.05;48 h: (7.5 ±1.3)% vs (6.6 ±0.5)%]. Conclusion The increased early apoptosis rate of intestinal mucosal epithelial cells might contribute to the stress-damage of the intestinal mucosa barrier in early stage of traumatic brain injury.
7.Questionnaires on male sexual dysfunction and their clinical application.
Yang CAI ; Tao WANG ; Ji-Hong LIU
National Journal of Andrology 2014;20(9):840-845
With the increasing incidence and prevalence of male sexual dysfunction, andrologists are more and more in need of accurate and efficient tools to assess therapeutic efficacy and patients' satisfaction and to help patients achieve satisfactory treatment results. This article summarizes some of the most commonly used questionnaires for the diagnosis and assessment of the treatment of male sexual dysfunction, including International Index of Erectile Function (IIEF), Erection Hardness Score (EHS), Quality of Erection Questionnaire (QEQ), Erectile Dysfunction Inventory of Treatment Satisfaction (EDITS), Treatment Satisfaction Scale (TSS), Self-Esteem and Relationship (SEAR), Premature Ejaculation Profile (PEP), Premature Ejaculation Diagnostic Tool (PEDT), Index of Premature Ejaculation (IPE), Arabic Index of Premature Ejaculation (AIPE), Aging Male Symptoms Scale (AMS), Androgen Deficiency in the Aging Male (ADAM), and Symptomatic Inventory for Screening Late-Onset Hypogonadism in Males (SILOH), and presents an overview on their clinical application.
Erectile Dysfunction
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Humans
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Male
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Surveys and Questionnaires
8.The consequence of Infection of Ureaplasma Urealyticum in the Pregnant Women
Zujing YANG ; Yuee CAI ; Lei WANG
Journal of Chinese Physician 2001;0(04):-
Objective To investigate influence of ureaplasma urealyticum(UU)infection on low genital tract during the pregnancy.The ureaplasma urealyticum was detected by the polymerase chain reaction(PCR) in women vaginal discharge. The patients were divided into infection group and control group.Results 624(25 68%) in 2430 cases of vaginal discharge had ureaplasma urealyticum infection. Infection rates of ureaplasma urealyticum was 24 53% in second trimester and 28 86% in third trimester respectively.184 cases (32 05%) of the premature rupture of membranes in infected group were significantly higher than 20 cases(22%) in control group. The UU infection incidence in small for gestation(SGA) age was increased in the infection group (45/574 vs 2/100)P
9.Effect of humidified high flow nasal cannula on severe apnea in preterm infants
Yan CAI ; Zuming YANG ; Sannan WANG
Chinese Pediatric Emergency Medicine 2014;21(12):790-794
Objective To investigate the effect of humidified high flow nasal cannula (HHFNC) on severe apnea in preterm infants.Methods Eighty-two preterm infants who developed apnea more than twice in short time,recurred within 6 hours or needed mask respirator were divided into HHFNC group(n =40) and nasal continuous positive airway pressure(NCPAP) group (n =42).Both groups were given aminophylline intravenously.The total therapeutic effect rate,the number of cases who needed mechanical ventilation during the observation period,the duration of non-invasive ventilation,the duration of oxygen therapy,the oxygen exchange indexes and the complications of two groups were observed.Results There were no significant differences between two groups in the therapeutic effect rate,the number of cases who need invasive ventilation,the duration of non-invasive ventilation time,oxygen exchange indexes and the duration of oxygen usage (P > 0.05).The numbers of nose injury of HHFNC group were less than those of the NCPAP group [10.0% (4/40) vs.30.9% (13/42)] (P <0.05).No significant differences were found between two groups in the complication of necrotizing enterocolitis or feeding intolerance,respiratory infection,retinopathy of prematurity,bronchopulmonary dysplasia (P < 0.05).Conclusion HHFNC has the same effect as NCPAP in the treatment of severe apnea in preterm infants except for lower prevalence of nose injury.