1.Emergency diagnosis of severe myocardial contusion
Journal of Chongqing Medical University 2007;0(11):-
Objective:To evaluate the emergency diagnosis of severe myocardial contusion. Methods:Thirty patients with serious blunt chest trauma underwent sonourethrography,all of whom underwent conventional myocardial markers simultaneously.All the observation time phases were set as 1 h,2 h,4 h and 8 h after injuries. Results:Both the concentrations of cardiac troponin T (cTn-T)and cardiac troponin (IcTn-I)at 8h after injuries were significantly higher than those at 1h after injuries(P
2.Strategies for constructing pharmaceutical subject repository union in China
Chinese Journal of Medical Library and Information Science 2017;26(4):40-46
The strategies for constructing pharmaceutical subject repository union in China and the development trend of pharmaceutical subject repository union were studied form the aspects of its cooperation models, platform building, resources acquisition and organization, access policy formation;copyright, quality control, and fund source.The cooperation models were divided into centralized storage model, distribution acquisition model and hierarchical construction model.Pharmaceutical subject repository union platform was built according to the different cooperation models.
3.Effect of Ho flavored Dingchuan Decoction on chronic bronchitis rats oxidant related indicators
Chinese Journal of Primary Medicine and Pharmacy 2013;20(19):2909-2911
Objective To study chronic bronchitis rats oxidant/antioxidant related indicators Ho flavored Dingchuan Decoction.Methods 50 SD rats were adopted improved smoked method to make chronic bronchitis model.From the 20th day of the modeling,blank control group and model control group gavage were treated with saline.The positive control group were treated with Cough Mixture.The experimental groupwere dealed with Ho flavored Dingchuan Decoction high,medium and low-dose.20 day later,the cotent of SOD,CAT,MDA in rat serum,lung tissue and balf were observed.Results Compare to blank control group,the cotent of SOD[(188.11 ± 9.37)U/ml、(276.11 ±30.28) U/ml,(8.80 ± 1.49)U/ml],CAT[(9.40 ±2.04)U/ml,(26.57±4.26)U/ml,(1.58±0.26) U/ml] in rat serum,lung tissue of the experimental group significantly reduced (P <0.01) ; MDA [(5.64 ± 0.52) μmol/L,(6.32 ± 2.10) μmol/L,(28.08 ± 2.43) μ mol/L) increased (P <0.05 or P < 0.01).Ho flavored Dingchuan Decoction can effectively reverse these changes,and showed a significant dose-dependent.The Ho flavored Dingchuantang,in middle and high-dose serum SOD [(253.05 ± 7.81) U/ml,(256.92 ± 5.37)U/ml],CAT [(14.86 ± 2.49)U/ml,(18.22 ± 2.65)U/ml] higher than those of blank control group.And the Ho flavored Dingchuantang,in middle and high-dose lung tissue SOD [(470.91 ± 11.46)U/mgprot,(482.91 ± 14.32)U/mgprot),CAT [(46.87 ± 3.75)U/mgprot,(55.49 ±3.33)U/mgprot] higher than those of blank control group.Content close to the normal level.Conclusion The Ho flavored Dingchuan Decoction has significantly reduce the oxidative stress in chronic bronchitis.
4.Clinical effect of compound anisodine on patients with paralytic strabismus and the influence on malondialdehyde and superoxide dismutase
International Eye Science 2016;16(10):1902-1904
AIM: To investigate the clinical effect of compound anisodine on patients with paralytic strabismus and the influence on malondialdehyde ( MDA ) and superoxide dismutase ( SOD) .
●METHODS: Seventy cases diagnosed with paralytic strabismus from Jun. 2008 to Dec. 2014 were selected as treatment group; another 70 cases with paralytic strabismus from Oct. 2000 to Jan. 2008 were chosen as control group. The control group was given with conventional therapy, and treatment group was additionally injected with compound anisodine subcutaneously on the basis of the control group. Treatment lasted for two courses about 28days. The effect of compound anisodine on patients with paralytic strabismus was evaluated and the serum level of MDA and SOD was also measured before and after treatment.
●RESULTS: ln treatment group, 54 cases were cured (77%), 14 cases improved (20%) and 2 cases had no response ( 3%) and total efficiency reached to 97%. ln control group, 32 cases were cured ( 46%) , 21 cases improved ( 30%) and 17 cases had no response ( 24%) and total efficiency was 76%. The cure rate and total efficiency of treatment group were significantly higher than that of control group (P<0. 05). Before treatment, the level of SOD and MDA was equal in two groups. After treatment, increased SOD level and decreased MDA level was observed in both groups. However, compound anisodine were significantly increased SOD level and reduced MDA level when compared with conventional therapy (P<0. 05).
●CONCLUSION: The compound anisodine shows the beneficial effect on patients with paralytic strabismus. Compound anisodine may exert the effect via increasing SOD and reducing MDA.
5.Enhancement of baicalin percutaneous penetration by azone and oleic acid
Chinese Traditional and Herbal Drugs 1994;0(07):-
Objective To study the effect of azone,oleic acid,and their combination on the trans-dermal obsorption of baicalin.Methods Improved Franz-cells and HPLC were used for the transdermal study.The effect of azone,oleic acid,and their combination on the transdermal absorption of baicalin was studied using uniform design.Results The 24 h penetration amount of baicalin was obtained as 466.11 ?g/cm~2 and 77.34 ?g/cm~2 when the azone concentration was 10% or the oleic acid concentration was 14%,respectively.When using a combination of azone and oleic acid in the ratio of 10%∶0.5%,the 24 h penetration amount of baicalin was 641.88 ?g/cm~2 and the enhancement ratio of penetration was 146.69.Conclusion Both azone and oleic acid could improve the skin penetration amount of baicalin.Combinated application of azone and oleic acid could further enhance baicalin transdermal delivery rate.The maximum penetration amount of baicalin is obtained by using a combination of azone and oleic acid in the ratio of 10%∶0.5%.
6.Comparison of treatment effects of different dosage of tamsulosin for patients with type Ⅲ prostatitis
Chinese Journal of Primary Medicine and Pharmacy 2017;24(20):3137-3140
Objective To compare the treatment effects of different dosage of tamsulosin for patients with type Ⅲ prostatitis.Methods 150 patients with type Ⅲ prostatitis were selected as study objects.They were divided into control group and research group according to the digital table,each group in 75cases.The research group was treated with tamsulosin 2 tablets (0.4mg),1 time a day.The control group was treated with tamsulosin 1 tablet (0.2mg) + starch tablet 1 tablet,1 time a day.After treatment for 12 weeks,the clinical effects,NIH-CPSI score,white blood cell count and pH value,and adverse reaction between the two groups were compared.Results The total effective rate of the research group was higher than that of the control group(93.33% vs.81.33%),the difference was statistically significant (x2 =4.881,P < 0.05).After treatment,the pain,voiding symptoms,quality of life and NIH-CPSI scores in the research group were (5.13 ± 4.02) points,(2.52 ± 1.07) points,(3.64 ± 3.25) points,(9.19 ± 0.63) points,respectively,which were lower than those in the control group [(8.25 ± 3.54) points,(3.28 ± 1.87) points,(5.57 ± 3.62) points,(16.47 ± 0.38) points],the differences were statistically significant (t =5.044,3.055,3.436,85.693,all P <0.05).The white blood cell and pH value of the research group were (12.65 ± 5.88) x 109/L,(6.29 ±0.20),respectively,which were lower than those in the control group [(16.58 ±6.24) x 109/L,(6.73 ± 0.16)],the differences were statistically significant (t =3.970,14.878,all P < 0.05).The single occurrence rate and total occurrence rate between the two groups had no statistically significant differences (x2 =0.340,0.207,0.000,0.000,0.362,all P > 0.05).Conclusion The effect of tamsulosin in dose of 0.4 mg is better than 0.2 mg,and had no significant impact on safety.
7.A Controlled Study of Executive Function in Heroin Addicts
Chinese Mental Health Journal 2002;0(10):-
Objective: To investigate the effect of heroin on executive function in heroin addicts Methods: Executive function of thi rty-six heroin addicts and thirty-six normal controls was assessed with a batter y of neuropsychological evaluation instruments in Chengdu city of China The to ols include of block design test, Stroop test (C, CW), Wisconsin card sorting te st (WCST-M)Results: There were significance difference between the two groups, heroin addicts had lower score of Block design and more time spent, number of errors in Stroop test (C、CW) Further more, the addicts had more total error, perseverative err o rs and lower number of categories in WCST than control group (P
8.Design and application of data acquisition system of biochemical analyzer
Chinese Medical Equipment Journal 2003;0(12):-
This paper presents a new design method and basic principle for the data acquisition system of the biochemical analyzer. The hardware, software configuration and principle of A/D converter module are also introduced. Field experiment shows that the system is effective and can satisfy related accuracy specification.
9.Chronic Obstructive Pulmonary Disease Patients with Gram-negative Bacteria Nosocomial Pneumonia
Chinese Journal of Nosocomiology 2004;0(10):-
OBJECTIVE To study the organism and drug resistance in chronic obstructive pulmonary disease(COPD) patients with Gram-negative bacteria(GNB) nosocomial pneumonia,in order to provide the index to clinician. METHODS The bacteria were tested by Micro WalkAway-40 which made in the USA,the susceptibility test was carried by disk diffusion test. RESULTS The rates of Klebsiella pneumoniae and Pseudomonas aeruginosa among all bacteria were higher,which were 26.8% and 26.2%,respectively;the organisms were almost drug resistant,which were more sensitive to imipenem,amikacin and ceftazidime,and more resistant to other drugs. CONCLUSIONS The hospital should make precautions,diagnose in time,and use antibiotic reasonably.
10.Delayed Healing and Reason Analysis of Obstetric Abdomen Vertical Cut and Preventive Nursing Countermeasure
Chinese Journal of Nosocomiology 2004;0(10):-
OBJECTIVE To analyze the reason for delayed healing of obstetric abdomen vertical cut and discuss the preventive nursing countermeasure.METHODS The discharged cases during Jul 2005 Jun 2006 and the inpatient cases during Jul 2006 to Jun 2007 were observed and monitored and at the same time the preventive nursing countermeasure was provided and the statistic of clinic material of two years was analyzed.RESULTS A satisfying effect has been made by taking objective monitoring and preventive nursing countermeasure the rate of delayed healing of obstetric abdomen vertical cut been reduced from the original 2.75% to the current 0.93%.CONCLUSIONS The key to prevent the delayed healing of obstetric abdomen vertical cut is prevention.Taking objective monitoring and preventive nursing countermeasure play an importment role in promoting healing of obstetric abdomen vrtical cut.