1.Theory of the spleen and stomach and AIDS prevention and treatment by TCM
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(07):-
Theory of the spleen and stomach is an important component of TCM.In the article,the author introduced the principal knowledge of spleen and stomach in TCM,the recognition of AIDS in TCM,the application of theory of spleen and stomach in prevention and treatment for AIDS.It had important significance for theory of spleen and stomach in treating and preventing AIDS.
2.Effect of ketamine on apoptosis and synaptophysin expression in hippocampal neural cell of SD infant rats
Journal of Third Military Medical University 2003;0(20):-
Objective To observe the effect of ketamine on apoptosis and synaptophysin expression in 7-day-old infant SD rat hippocampal neural cells. Methods Thirty SD rats of 7 days old were randomly assigned to receive the injection of 25 mg/kg ketamine (K_ 1 group)or 50 mg/kg (K_ 2 group) or 50 ml/kg normal saline (K_ 0 group). In 24 h after injecton, all rats were killed and the synaptophysin was tested by using immunhistochemistry and Western blotting, the apoptosis of neuronal cell by Tunel. Results In 24 h after injection of ketamine,the number of apoptotic neural cells increased,which of K_ 0 group was (5.3?1.7), K_ 1 group (9.5?4.2), K_ 2 group (23.4?7.6), and the grey values of synaptophysin by immunhistochemistry of K_ 0 group was (174.11?4.68), K_ 1 group (181.36?4.17), K_ 2 group (198.25?3.06), and the OD values of synaptophysin piece decreased, which of K_ 0 group (4 007?758), K_ 1 group (2 621?465), K_ 2 group (987?183). Conclusion In 24 h after treatment with ketamine, the expression of synaptophysin was decreased in hippocampl neural cells, the number of apoptotic neuronal cells were increased, which may be involved in neurotoxicity caused by ketamine.
3.Differences in lymphocytes and the expression of FasL,ICAM-1 in the tonsillar HEVs associated with IgA nephropathy and recurrent tonsillitis
Zhibin WANG ; Yang LIU ; Shenghong LIU
Chinese Journal of Immunology 2001;0(10):-
Objective:To investigate the difference in expression of FasL and ICAM-1 in the tonsillar HEV associated with IgA nephropathy (IgAN) and recurrent tonsillitis (RT).Methods:Human tonsils were obtained from the patients with RT (n=18) or IgAN (n=12).HE staining was used to show the morophometry of the tonsillar HEV.CD20+,CD3+ lymphocytes and distribution of FasL and ICAM-1 in the HEV were observed with immunohistochemical stained tissue section.The quantitatively experimental data from pathological image analysis were compared between IgAN and RT group.Results:(1)The expressing intensity of ICAM-1 was (0.435 5?0.002) in IgAN group and (0.239 5?0.010 4) in RT group,respectively (P0.05).Conclusion:A significant increase in the number of tonsillar HEV and increased lymphocytes in HEVs may indicate the abnormalities in peripheral blood in the patients with IgAN,thus leading to an overactivation of the tonsillar HEVs that induce Fas-dependent apoptosis in such patients.A stronger biological effective adhesion molecule promotes the transendothelial migration of lymphocytes across HEVs of palatine tonsil,which appears to be connected with the development of IgAN.
4.Effect of Combined Acupuncture and Medicine on Learning-Memory Ability and Free Radical System of Hippocampus in Vascular Dementia Rats
Wenmin NIU ; Zhibin LIU ; Xiaohang YANG
Journal of Zhejiang Chinese Medical University 2006;0(05):-
[Objective]To explore the effect of combined acupuncture and medicine on learning--memory abilities,and free radical system of hippocampus in vascular dementia(VD)rats.[Methods]The 48 Sprague Dawley rats were randomly divided into control(1),VD model(2),VD plus removed olfactory bulb model(3)and XIU Three Needles(4),Eugenol(5),combined acupuncture and medicine(6)groups.Morris maze tests were conducted for valuating the learning and memory abilities.The contents of MDA,SOD and GSH-Px activity of hippocampus were detected.[Results]In comparison with group 1,the average escape latency and travel distance prolonged significantly in group 2.In comparison with group 2,it shortened remarkably in groups 4 and 5.No significant differences were found between groups 1 and 2.In comparison with group 6,it prolonged in groups 4 and 5.No significant differences were found between them.The MDA content of hippocampus in VD model group was higher than that of control group(P
5.THE PREVENTIVE EFFECT OF HEALTH EDUCATION ON RECURRENCE OF VAGINITIS A-MONG GUANGZHOU'S CAREER WOMEN
Zhibin LI ; Lijuan YANG ; Huihua XIAO
Modern Hospital 2015;(7):152-153,156
Objective To investigate the preventive effect of health education on prevention of vaginitis among Guangzhou ’ s career women.Methods 479 career women with confirmed diagnosis of vaginitis in 2013 were cured and followed up for 1 year.Pa-tient were divided into Control Group (n=202) and Observation Group (n=277) according to whether accompanied the health edu-cation on prevention of vagnnitis.The recurrence rate of vaginitis during the 1 -year follow -up was compared between the two groups.Results In Control Group, 192 patients (95.05%) finished the follow -up, and in Observation Group, 260 patients (93.86%) finished the follow-up, there was not statistical difference in accomplishment ratio of follow -up (p>0.05).The recur-rence of rate of vaginitis was statistical higher in Control Group (72/192, 37.50%) than that in Observation Group (64/260, 24.62%) (P<0.05).Conclusion Health education could reduce the recurrence rate of vaginitis significantly.
6.Fibrosis in Skeletal Muscle: Celluar and Molecular Mechanism (review)
Xiuyuan DENG ; Zhibin WU ; Zhong YANG
Chinese Journal of Rehabilitation Theory and Practice 2014;(2):142-147
Skeletal muscle has high regenerative capability. It is able to regenerate completely after acute traumatic damage, while the repairing process often accompanied by fibrosis in the chronic degenerative conditions such as muscular dystrophy and repeated muscle fiber damage. Through in-depth study on the mechanisms of skeletal muscle fibrosis in the past decade, it has been found that a variety of cells and regulatory molecules involved in the process, especially muscle satellite cells-derived myofibroblasts, transforming growth factor β (TGF-β) and other fibrosis promoting growth factors. This review focused on the cellular and molecular mechanisms of the skeletal muscle fibrosis and relevant antagonistic strategies.
7.The experience of diagnosis and treatment of primary ureteral polyps:a report of 27 cases
Min GUO ; Yingguo TU ; Jianchang YANG ; Zhibin LI ; Zhaoming XIA
Chinese Journal of Primary Medicine and Pharmacy 2014;(20):3070-3071
Objective To explore the diagnosis ,treatment methods and clinical features of primary ureteral polyps.Methods Clinical data of 27 cases with primary ureteral polyps were analyzed retrospectively .The clinical features and treatment of this disease were analyzed .Results 7 cases were treated with polypectomy ,10 cases with basement fulguration by ureteroscopy operation or polyps-removing by ureter forceps ,4 cases with distal ureter resec-tion and termino-terminal anastomosis ,4 cases with lesions ureter resection and bilateral ureteric reimplantaion and 2 cases with nephrectomy due to nonfunctioning kidney .All cases were confirmed to be primary ureter polyp by pathology.All cases were followed up for 6-12 months with no recurrence and canceration ,only 1 case had ureteral stenosis.Conclusion Primary ureteral polyps is a benign disease with rare malignancy .The primary and effective treatment method is surgery which has few complications and good effect .
8.Military medical literature collection:construction and analysis
Wei LIU ; Jiying HAO ; Li SHENG ; Zhibin YANG ; Songjun WANG
Military Medical Sciences 2014;(10):823-827
Objective To explore the way to compile a global military medical literature collection and perspectives for its research.Methods The names of military medical research institutions and their trends of development were summa-rized via semantic analysis.The collection of retrieval words for military medical research institutions( then the collection) was constructed based on expert consultation.The names of military medical research institutions were collect-ed with manual screening after retrieval withthe collection.The literature collection of military medical research institu-tions was completed with coordinated retrieved of their papers and other publications.Results According to different needs of information analysis, the literature collection of military medical research institutions could be analyzed in terms of their size, types of development, and academic authority.Conclusion Based onthe collection, the military medical research institutions collected in this article included institutions that used to be neglected during the course of information tracking of military medicine.Three kinds of institutions should be paid more attention to.The institutions were the ones with a large number of papers and citations, the ones whose papers increased or decreased dramatically, as well as the ones whose research directions were the priority fields of Chinese PLA.
9.Quantitative assessment of early acute pulmonary embolism in rabbits with pulmonary hypertension with E-index, M-index
Zhibin CONG ; Weidong REN ; Chunyan MA ; Yujie YANG ; Bin JIANG
Chinese Journal of Interventional Imaging and Therapy 2010;7(1):50-53
Objective To explore the variation of E-index and M-index of rabbits with acute pulmonary embolism (APE) under the status of pulmonary hypertension (PHT). Methods Rabbit models of APE with PHT were established. A series of parameters [including peak early diastolic mitral inflow velocity (EM), peak late diastolic mitral inflow velocity (AM) and so on] were obtained with routine echocardiography and tissue Doppler imaging (TDI);and then E-index, M-index were calculated. The parameters before and after APE were compared. Results Twenty-three rabbit models with APE were successfully established, but 3 with atrial fibrillation were excluded. After APE, pulmonary artery pressure increased significantly, EM decreased observably, whereas right ventricular myocardial performance index (RVMPI) increased more evidently than left ventricular myocardial performance index (LVMPI) (P<0.01) did and E-index decreased and M-index increased remarkably. Conclusion Changes of E-index and M-index may provide reference for quantitative assessment of early APE.
10.The expression of HMGB1 in nasal mucosa of allergic rhinitis patients and its significance
Yang LIU ; Zhibin WANG ; Zheng LIU ; Yonghua CUI
Chinese Journal of Immunology 2001;0(07):-
Objective:To investigate the expression of HMGB1 in the nasal mucosa of allergic rhinitis patients and its significance.Methods:Immunohistochemistry and RT-PCR methods were used to measure the expression of HMGB1 protein and mRNA in inferior turbinate mucosa from 12 allergic rhinitis patients and 11 control patients respectively.Results:The relative expression level of HMGB1 mRNA in nasal mucosa was significantly increased in allergic rhinitis patients compared with that of normal controls (P