Objective To investigate the epidemiological characteristics of imported malaria in Hailing District ,Taizhou City,so as to provide the evidence for formulating the effective prevention and control strategy. Methods The network reports, questionnaires and epidemic reports of imported malaria cases in Hailing District from 2010 to 2015 were collected and analyzed retrospectively. Results From 2010 to 2015,totally 46 cases of imported malaria were reported,including 40 cases of falci?parum malaria(86.96%),4 cases of ovale malaria(8.70%),1 case of quartan malaria(2.17%)and 1 case of multi?infection of falciparum malaria and tertian malaria(2.17%). No seasonal trend of time of the disease onset was observed. All the patients were return abroad with clear residence histories in malaria epidemic areas. The average time from disease onset to definite diag?nosis was 2 d and 8 patients were definitely diagnosed within 24 h. All the 46 patients were cured. Conclusion All the malaria cases reported were imported cases in Hailing District in the last five years. Effective prevention and control measures are the key to the malaria elimination.

High-consuming group is a special group which has good economic base, differmental culture and relgional belif customs. These patients alwanys need high quality medical service. How to integrate with these characteristics and make the nursing model of making patients' belife, moral ideas respcted, and rights proteded is a difficult problem. The author put forward we should rule nurse staff' s ethics and actions, provide a medical envionment from which can meet high-consuming patients physical and mental needs.

Objective To understand the current status of Oncomelania hupensis snails and the change rules,so as to pro?vide the evidence for formulating the snail control strategy. Methods The data of snails were collected and the factors influenc?ing the changes of snail status were investigated,and all the data were analyzed in Hailing District from 2007 to 2014. Results There were 18 environments with snails in 17 villages of 3 townships in Hailing District from 2007 to 2014. The snail area was 7.832 4 hm2. Among these environments and snail areas, 6 environments and 2.134 5 hm2, snail area were detected by the village snail investigation groups, and 12 environments and 5.697 9 hm2 snail area were detected by the township snail investigation groups. In addition, in 5 non?endemic villages, 3.126 3 hm2 snail area was found. In 2008, 2012 and 2013, a total of 2.274 0 hm2 snail area was found again. Conclusions In recent years,the snail situation rises again after schistosomiasis transmission has been interrupted. Therefore,this situation should be paid attention to.

Objective To determine the mercury in seven kinds of algal plant drugs.Method The mercury in the samples was determined by the atomic fluorescence spectrometry after been digested by microwave.Results The detection limit of mercury was 0.045?g?L~(1).The relative standard deviation was 1.65% and the average recovery was 97.77%.Conclusion The method had the advantages of simple operation,higher precision,higher sensitivity and repeatability and was suitable for the determination of mercury in the algal plant drugs.

Objective To explore the relationship between type D personality,anxiety and depression of coronary heart disease(CHD) and the effects on quality of life (QOL).Methods 296 CHD patients were randomly chosen to answer the questionnaires of general situation,type D personality scale (DS14),Self-rating Anxiety Scale(SAS),Self-rating Depression Scale (SDS) and Short-Form Health Survey (SF-36).Results Of all subjects 37.2％ were identified as type D personality,detection rates of anxiety and depression was were higher than the patients with non-type D personality (33.6％ vs 14.0％,49.1％ vs 23.1％,separately) (P＜ 0.01).The scores of role-physical (RP),bodily pain (BP),general health (GH),vitality (VT),social functioning (SF),role-emotional(RE),mental health (MH) in patients with type D personality ((32.73 ± 42.52),(57.68 ± 26.93),(42.14 ±18.23),(47.15 ±22.60),(59.43 ±26.67),(45.91 ±46.22),(49.25 ±22.21),separately) were lower than the patients with non-type D personality ((56.00 ± 46.61),(64.62 ± 22.27),(48.27 ± 19.19),(61.56 ±20.17),(69.70 ± 24.35),(70.79 ± 44.53),(70.52 ± 18.91),separately) (P＜0.05 or 0.01).Multiple stepwise regression analysis showed that depression,type D personality,anxiety,coronary artery stenosis degree and degree of education were entered QOL regression equation(β =-16.31,-6.53,-7.69,-15.75,2.64,P ＜ 0.05).Conclusion The type D personality of CHD exist high prevalence of anxiety and depression disorders,and the type D personality influence the QOL of patients with CHD.

Objectiveto investigate the effect of the scientific research projects established within the Hospital on mobilizing the enthusiasm of the medical staff of the Hospital,improving their scientific research quality,and promoting the scientific research development of the Hospital.Methods through analyzing the devotion to the projects within the Hospital and establishment of projects out of the hospital in recent 8 years,as well as output of scientific research achievements and paper publication.ResultsThe scientific research output is increased significant than the previous years,activities of the researchers were encouraged,financial fund is increased somewhat,and the level of research achievements and paper publication are increasing gradually year by year.ConclusionsThe scientific research projects established within Hospital play a promotion role for the development of scientific research of the Hospital.

N-terminal pro-B-type natriuretic peptide (NT-proBNP) is a good plasma marker for the diagnosis and differential diagnosis of the heart failure.For decompensated heart failure,the double-cut-point strategy including the diagnostic cut-off point and eliminated cut-off point was suggested,and the diagnostic cut-off point can be further divided according to age to further improve the diagnostic accuracy.If the patient's value was in gray interval,doctors should further analyzed the possible confounders,including age,renal function,BMI et al.Recently,more researches were carried out for NT-proBNP in patients with acute coronary syndrome,and some studies showed that its combination with troponin increased the diagnostic efficacy of acute myocardial infarction.The studies of NT-proBNP were still carried out in other areas including atrial fibrillation,cardiomyopathy,valvular disease,pulmonary embolism et al and had obtained the results of the beneficial clinical applications.

Objective To evaluate and compare the efficacy and toxicity of gemcitabin(GEM) plus cisplantin and GEM on the chemotherapy of elderly patients advanced non-small-cell lung cancer (NSCLC).Methods 85 elderly patients with stage 3 to 4 NSCLC were randomized into gemcitabine plus cisplatin (group GP) and GEM (group GEM).In group GP,patients received GEM on day 1 and day 8 at dose 1.0 g/m2,add cisplatin on day 2 to day 4 at dose 75 mg/m2. In group GEM, patients would received single GEM at dose 1.25 g/m2.The the therapy circle was 3 weeks and undertaken least 2 circles before the treatment efficacy and survival would be evaluated according RECIST. Results In GP group the response rate was 48.84 ％(21/43),In GEM group the response rate was 35.71％(15/42),the difference of response rate between two groups was not statistically significant(x2=1.708,P=0.424).The median survival were 11 months to Gp group and 9 months to GEM group. The 1 year survival rates of GP group were 39.53 ％ and of GEM group were 26.19 ％. The survival time between two groups was not statistically significant(t=1.377,P=0.172).The same toxicity in both groups was defected, Nausea and vomiting occurred were more serious in GP group than that in GEM group (x2=9.796, P=0.002). Conclusion GP and GEM are both effective for treatment of elderly advanced NSCLC.There are no significantly differences on efficacy and toxicity in 2 groups. Side effects on alimentary system are obviously less in GEM group than that in GP group.

BACKGROUND: A large amount of studies have demonstrated that stem cells in the heart of mammal participate in heart self-renewal and endogenous repair.OBJECTIVE: To summarize the source, classification, features of cardiac stem cells and application in heart disease. METHODS: A computer-based online search of PubMed database was performed for articles published between January 2000 and December 2010 related to the source, classification, features of cardiac stem cells and its effects on myocardial regeneration with key words cardiac stem cell. Clinical studies and basic studies were all included. Repetitive studies and Meta analysis were excluded. Finally, 32 articles were included.RESULTS AND CONCLUSION: Cardiac stem cell is a type of stem cells in the heart, with properties of self-renewal and cloning proliferation. It can differentiate into cardiomyocyte and endothelial cell and plays a role in heart injury repair to improve heart function. Cardiac stem cells have been in vitro isolated, cultured and amplified to transplant into animal heart, which lays a foundation for clinical application. However, some questions remain poorly understood as to the homeostasis and dynamic changes, processes involved in their differentiation into heart functioning cells, as well as influential factors and regulation.

Objective To study the effect of chitosan on the growth of the in vitro cultured retinal nerve cells. Methods The retinal nerve cells of SD baby rats were cultured in vitro. The effects of chitosan at 0.065%,1.25%,2.5%,5%,10%,15% on the growth of the retinal nerve cells were measured by MTT method. The blank control group was created. Results 1.25%,2.5%,5%,and 10% chitosan could obviously promote the growth of retinal nerve cells,and 10% chitosan was the optimal concentration for the growth of nerve cells. Conclusion Chitosan can effectively promote the growth of retinal nerve cells,and it is necessary to undertake the further study of Chitosan.