In this article,the author introduced their experiences,investigated the importance,connotation,and strategy of aesthetic education to the medical students and put forward some suggestions on aesthetic education in medical education in order to cultivate multiple qualifications of medical students.

The impact of market economy and the pressure of professional title upgrading have posed an effect on the psychology and behavior of clinic research personnel in their research activities.Clinic research personnel should positively modify their think- ing,regulate their scientific behavior and recognize correctly the guidance of their research in medical field so as to play and im- portant role as a motivation to the improvement of medical level and the whole development of the science.

Humanity quality is the essential manifestation of general characters such as hu-man knowledge and human spirit.In this article,we investigated the importance,meanings and measures of the education of humanity quality in medical teaching in order to reinforce the education of humanity quality of medical students and train excellent medical talents with advanced professional technology,magnificent professional ethics and healthy mental quality.

To evaluate the clinical efficacy and safety of Danhong injection in the treatment of cerebral infarction.A total of 27 randomized controlled trials were retrieved from the literature and analyzed by Meta-analysis with RevMan 5.0 software.All were at level B or above after quality assessment.The clinical efficacy of Danhong injection was better than that of the control group in the treatment of cerebral infarction( RR =1.21,95％ CI:1.17 - 1.26 ).After the administration of Danhong injection,the score of National Institute of Neurological Disorders and Stroke (NIHSS) and hemorrheologic indices were significantly lower than those of the control group (P ＜0.01 ).There was no obvious adverse reaction.The clinical efficacy and safety of Danhong injection have marked advantages over Danshen and Fufang Dansheng injection in the treatment of cerebral infarction.

BACKGROUND:Tissue engineering bone application for repairing critical-size segmental defects is stil in research stage. The ideal construction methods have not yet been found.
OBJECTIVE:To review the research literatures on tissue engineering bone scaffold material, its shape and effect on the loading of seeding cells, seek appropriate engineered bone scaffolds which are capable of loading a large number of cells effectively and probably, and provide a new way of repairing segmental bone defects.
METHODS:The first author performed a data retrieval of PubMed and Wanfang databases from 1994 to 2013, to search the articles addressing the construction method of tissue engineering bone scaffold, and reviewed the literatures systematical y.
RESULTS AND CONCLUSION:A total of 379 references were retrieved, including 161 articles in Chinese and 218 articles in English. According to the inclusion and exclusion criteria, 53 articles were final y involved in the analysis. The analysis results indicated that, the needed volume of bone tissue engineering scaffolds for critical-sized section bone defect reconstruction is big, which needs to load a huge number of seed cells. If there is no suitable forms and shapes for celladhesion, the property of so-cal ed engineered bone is similar to pure artificial bone implants. The effective load of seed cells on engineering bone scaffold material and keeping the activity is the first step in clinical practice, as wel as the important guarantee for loading bioactive seed cells. Hence, a more simple and accurate detection method for loading cellquantity is needed. Looking into the retrieved content, effective load cellquantity and its bioactivity are detected by indirect methods, supporting the effectiveness of cellseeding. Some methods can guarantee the cellquantity and seeding pattern, the real load is unknown as wel as the activity. Fabricating engineering bone scaffold into special form and shape are easy to effective seeding, proliferation and maintaining the biomechanical performance, inducing osteogenesis, and final y detecting the load cellquantity and activity on the scaffold through the simple and direct method.

In recent years,experts of international nephrology,emergency medicine and other disciplines tend to substitute acute kidney injury for acute renal failure.There is a new point of view about the definition,diagnostic criteria,staging,management and prognosis of acute kidney injury.With diagnostic criteria constantly updated,it comes up to an expectation of united criteria as well as reaching a consensus.Continuously looking for more suitable for both time window of clinical diagnosis and clinical observation indicators,and clinically making out much more scientific and reasonable standard of diagnosis and staging,which contribute to early detection and early intervention as a result of eventually mortality rate reduction.This paper gives an interpretation for the procedure of evolution about diagnostic criteria on acute kidney injury in children according to the related literatures updated in recent years.

OBJECTIVE:To establish a set of scientific,standard management model and rational,impartial financial system in Chinese institutes for drug control.METHODS:The types of the established institutions and the financial appropriation model of institutes for drug control in China were studied by using the methods of classification,comparison and analysis.RESULTS & CONCLUSIONS:Under super-ministry system,local management in drug control institutions at all levels is expected to be put into practice soon.It is advisable to optimize the organization and management model and financial appropriation management system such as by shifting from county level institution to district level institution and carrying out a wage system in drug control institutes in accordance with the payment level of civil servants,etc.

Objective:To discuss the important role of clinical pharmacists in the prevention of medication errors and rational drug use through medication reconciliation in endocrinology department. Methods: The medication reconciliation was given to the diabetic patients over 70 years old newly admitted in the endocrinology department from January to April 2016, and the consistency and appro-priateness of medication orders were verified and the results were collected and analyzed by the pharmacists. Results: Totally 84 pa-tients were enrolled into the research with the average age of (76. 3 ± 5. 0) and the average number of combined diseases of (3. 5 ± 1. 2). The average medications taken by the patients before the admission were (6. 7 ± 2. 9), and 22. 6% of the patients took tradi-tional Chinese medicines and 4. 76% of the patients took health products. The patients whose medications for 24h needed intervention accounted for 27. 38%, the medications orders needed intervention accounted for 3. 67%, and the intervention success rate of clinical pharmacist was 100%. Conclusion:To the patients over 70 years old with type 2 diabetes and multiple diseases treated with a variety of medications, medication reconciliation in 24 hours can effectively prevent the medication errors and promote the rational drug use.

MicroRNAs(miRNAs) are small non-coding RNAs of 20-24nt(about 22nt) in length that mediate gene expression at the post-transcriptional level by degrading or repressing target messenger RNAs (mRNAs).Angiogenesis plays an important role in occurrence and development of cancers which involves multiple signaling pathways.miRNAs can regulate the signaling pathways in which their target genes are involved.Therefore,to study the miRNAs regulation of tumor angiogenesis slgnaling pathways will contribute to cancer diagnosis and treatment.

ObjectiveTo investigate the effects of epinephrine in intestinal injury caused by lipopolysaccharide (LPS) in rats.MethodsFifty SD rats were randomly divided into five groups ( n =10 pet group ):saline control group received intravenous infusion of 0.9％ saline 2.4 ml/( kg· h) ;LPS group received intravenous injection of LPS 6 mg/kg;small-dose,medium-dose,and large-dose epinephrine treatment group received an intravenous infusion of epinephrine 0.12 μg/(kg· min),0.3 μg/( kg· min),and 0.6 μg/( kg· min)after LPS 6 mg/kg intravenous injection,respectively.Intestinal injury was evaluated by intestinal pathological examination.Blood samples were taken at 0,2 and 6 h after LPS infection,and the levels of serum TNF-α,IL-1β and IL-10 were detected by enzyme-linked immunoadsorbent assay.The pathological changes of intestine were observed at 24 h.ResultsPathological examination showed that LPS caused severe congestion,edema,neutrophil infiltration,hemorrhage and cell necrosis in intestine.Compared with LPS group,large-dose epinephrine ameliorated the damage of intestine.In LPS group,serum levels of TNF-α[ ( 1164 ± 145) ng/L],IL-1β[ (521 ±68) ng/L],IL-10 [ (303 ±20) ng/L] all increased compared with control group (P＜0.05)at 2 h.Compared with LPS group,serum levels of TNF-α[ (576 ± 105) ng/L] were significantly depressed (P＜0.05),whereas IL-10 was elevated at 2 h[ (424 ±29) ng/L] and6 h[ (245 ± 14) ng/L] (P＜0.05)in large-dose epinephrine treatment group.Serum IL- 1β levels were unaffected by large-dose epinephrine treatment.Small-dose and medium-dose epinephrine could not reduce the pathological injury of intestine induced by lipopolysaccharide.Compared with LPS group,levels of serum TNF-α,IL-1β and IL-10 were also unaffected by small-dose and medium-dose epinephrine treatment ( all P＞0.05 ) at any time points.ConclusionEpinephrine reduced the intestine injury caused by LPS by down-regulating pro-inflammatory cytokines production and up-regulate anti-inflammatory cytokines production.