1.Intrauterine Intussusception Presenting as Transient Fetal Ascites.
Jeong In YANG ; Haeng Soo KIM ; Seong Cheon YANG ; Hee Suk RYU ; Kie Suk OH
Korean Journal of Perinatology 2001;12(3):362-366
No abstract available.
Ascites*
;
Intussusception*
2.The changes of arterial and end-tidal carbon dioxide tension by respiratory rate and tidal volume.
Eun Kil RAH ; Hyun Joo OH ; Hong Suk YANG
The Korean Journal of Critical Care Medicine 1993;8(1):27-32
No abstract available.
Carbon Dioxide*
;
Carbon*
;
Respiratory Rate*
;
Tidal Volume*
3.Clinical Manifestations and Perinatal Outcomes in Pregnancies with Fetal Dysplastic Kidney Disease.
Kie Suk OH ; Haeng Soo KIM ; Jeong In YANG ; Joon Hwan OH ; Seung Seop KEUM
Korean Journal of Obstetrics and Gynecology 2000;43(1):43-50
OBJECTIVE: To obtain clinically useful data regarding prenatal diagnosis, proper antepartum counseling and obstetric management in pregnancies with fetal dysplastic kidney disease. METHODS: We retrospectively reviewed 13 cases of MCDK(Multicystic dysplastic kidney) and PCDK(Polycystic dysplastic kidney), diagnosed by antenatal ultrasound and delivered from June 1994 through July 1999 at Ajou University School of Medicine, Department of Obstetrics and Gynecology, with regard to prenatal ultrasonographic findings, perinatal outcomes, maternal complications and associated fetal anomalies. RESULTS: The incidence of MCDK and PCDK was one in 1,066 and one in 2,398 births, respectively. Of the 9 cases of MCDK, one case was terminated due to severely associated anomaly, and 6 cases were delivered by spontaneous labor or pitocin induction at term, of which 1 case was delivered by pitocin induction at 36 weeks gestation due to intrauterine fetal death. Two cases were delivered by cesarean section. There were no neonatal deaths in 7 cases of MCDK and they have been followed up to date, and alive. Of the 4 cases of PCDK, 3 cases were terminated by induced abortion or induced vaginal delivery, and 1 case was delivered by cesarean section, which was combined with hypertrophic cardiomyopathy, and the baby died within 24 hours after birth. Perinatal complications consisted of small for gestational age, urinary tract infection, hydronephrosis, acute respiratory failure, acute renal failure, periventricular hemorrhage and laryngomalacia in the neonatal period. CONCLUSION: It is suggested that antenatal ultrasonography and genetic analysis to evaluate accurate diagnosis and associated anomalies should be performed to manage and councel properly the pregnancies with fetal dysplastic kidney disease.
Abortion, Induced
;
Acute Kidney Injury
;
Cardiomyopathy, Hypertrophic
;
Cesarean Section
;
Counseling
;
Diagnosis
;
Female
;
Fetal Death
;
Gestational Age
;
Gynecology
;
Hemorrhage
;
Humans
;
Hydronephrosis
;
Incidence
;
Kidney Diseases*
;
Kidney*
;
Laryngomalacia
;
Obstetrics
;
Oxytocin
;
Parturition
;
Pregnancy*
;
Prenatal Diagnosis
;
Respiratory Insufficiency
;
Retrospective Studies
;
Ultrasonography
;
Urinary Tract Infections
4.A Clinical Review of the HELLP Syndrome.
Sang Tae AHN ; Haeng Soo KIM ; Jeong In YANG ; Joon Hwan OH ; Ki Su HAN ; Seong Cheon YANG ; Kie Suk OH
Korean Journal of Perinatology 2001;12(2):122-130
No abstract available.
Female
;
HELLP Syndrome*
;
Pregnancy
5.The Effect of Overweight and Pregnancy on Endocrinologic Features and Glucose Metabolism in Patients with Polycystic Ovarian Syndrome.
Kyung Joo HWANG ; Kie Suk OH ; Sei Kwang KIM ; Hyuck Chan KWON ; Young Han PARK ; Jung In YANG ; Hee Suk RHYU
Korean Journal of Obstetrics and Gynecology 1999;42(3):606-613
OBJECTIVE: The purpose of this study attempts to determine the endocrinologic characteristics and changes in glucose metabolism before/during pregnancy according to different body weights in women with Polycystic ovarian syndrome (PCOS). METHODS: 94 women dia with PCOS were evaluated through measuring serum hormone levels and oral glucose tolerance tests preconceptionally and gestationally. RESULTS: In patients who were of normal weight showed significantly increased serum LH levels compared to those who were overweight (12.8+/-0.9 Vs. 7.1+/-0.8 mIU/ml, p= 0.000), and the serum levels of insulin was increased significantly in the overweight group (7.1+/-0.7 Vs. 15.2+/-2.8 ulU/ml, p= 0.000). the IGFBP-I (32.8+/-10.6 Vs. 8.3+/-2.5 ng/ml, p=0.034) and SHBG (55.8+/-4.2 Vs. 37.1+/-3.1 nmol/ml, p= 0.001) were significantly lower in the ovnweight group. The oral glucose tolerance test before/after pregnancy showed increased frequency of abnormal glucose metabolism, in both of the non-obese group (38.8%, 26,9%) and the obese group (64.2%, 53.9%) compared with normal population. CONCLUSION: It is thought that in the normal weight group with polycystic ovarian syndrome androgen production is stimulated in the theca cells by abnormally high LH secretion, while in the overweight group the hyperinsulinemia state which decreases the SHBG and IGFBP-I, lead to increase biologically active hee androgens and IGF-I and increase insulin binding to its receptor. And during/before pregnancy, women with PCOS showed that incidence of abnormal glucose metabolism was significantly increased in both of non-obese and obese groups.
Androgens
;
Body Weight
;
Female
;
Glucose Tolerance Test
;
Glucose*
;
Humans
;
Hyperinsulinism
;
Incidence
;
Insulin
;
Insulin-Like Growth Factor I
;
Metabolism*
;
Obesity
;
Overweight*
;
Polycystic Ovary Syndrome*
;
Pregnancy*
;
Theca Cells
6.Clinical Diversities and Perinatal Outcomes of Nonimmune Hydrops Fetalis.
Suk Joon CHANG ; Haeng Soo KIM ; Jeong In YANG ; Eun Joo AHN ; Young Don LEE ; Kie Suk OH
Korean Journal of Obstetrics and Gynecology 1998;41(7):1927-1933
BACKGROUND: Nonimmune hydrops fetalis has become an important perinatal problem since it was first described in 1943. Although recent advances in antenatal ultrasound have made it possible to detect and manage nonimmune hydrops fetalis in early pregnancy, the perinatal mortality is still high. OBJECTIVE: To obtain clinically useful data regarding antenatal diagnosis, management, and perinatal outcomes of nonimmune hydrops fetalis, and to assist clinicians offer proper antepartum counseling and obstetric management which may be able to improve prognosis. Study design: We retrospectively reviewed 33 cases of nonimmune hydrops fetalis delivered in our hospital over a 4-year period. RESULTS: The antenatal diagnosis was possible by ultrasonography in all cases. Accumulation of fluid in fetal serous cavity and generalized skin edema were observed in all cases. A probable etiology was found in 23 (69.7%) cases through ultrasonography, various laboratory studies including fetal karyotyping, and autopsies. These were cardiovascular (4), respiratory (6), chromosomal (4), skeletal (1), and others (8). Despite extensive diagnostic studies, no definite etiology was found in 10 (30.3%) cases. Excluding the ten fetuses delivered after induced abortion, eight infants were born alive and six died in the neonatal period. The mortality rate was 91.3% (21/23). CONCLUSION: Nonimmune hydrops fetalis represents a very poor perinatal outcome. It is suggested that to improve the prognosis, various antenatal and postnatal approaches to find associated etiologic factors should be performed, and intensive perinatal cares are needed.
Abortion, Induced
;
Autopsy
;
Counseling
;
Edema
;
Female
;
Fetus
;
Humans
;
Hydrops Fetalis*
;
Infant
;
Karyotyping
;
Mortality
;
Perinatal Mortality
;
Pregnancy
;
Prenatal Diagnosis
;
Prognosis
;
Retrospective Studies
;
Skin
;
Ultrasonography
7.Prenatal Cytogenetic Diagnosis with Fetal Ascitic Fluid as a Rapid Chromosome Analysis.
Jeong In YANG ; Kie Suk OH ; Haeng Soo KIM ; Eun Joo AHN ; Jae Sun SHIM
Korean Journal of Obstetrics and Gynecology 1998;41(12):2997-3000
OBJECTIVE: The goal of this study is to determine the efficacy of rapid karyotyping from fetal ascitic fluid. METHODS: In three cases of isolated fetal ascites diagnosed by prenatal ultrasonography, ultrasound guided fetal paracentesis and amniocentesis were performed and successfully obtained. Fetal karyotyping in each case at 29, 30 and 32 weeks gestation using modified lymphocyte culture method was conducted. RESULTS: The chromosomal analysis was successful within 72 hours and abnormalities were detected in two cases and revealed trisomy 21 in each case. Our study demonstrated that the majority distribution of white blood cells was lymphocytes which ranged from 2.1 * 10(6) cells/ml to 3.7 * 10(6) cells/ml and the cell density for culture was at least than 0.35 * 10(6) cells/ml. CONCLUSION: The use of ascitic fluid as a cell source to achieve rapid fetal karyotyping can be valuable when cordocenteis or amniocentesis would be technically more difficult, or when rapid result is required for planning of perinatal management at late second or third trimester gestational age.
Amniocentesis
;
Ascites
;
Ascitic Fluid*
;
Cell Count
;
Cytogenetics*
;
Diagnosis*
;
Down Syndrome
;
Female
;
Gestational Age
;
Humans
;
Karyotyping
;
Leukocytes
;
Lymphocytes
;
Paracentesis
;
Pregnancy
;
Pregnancy Trimester, Third
;
Ultrasonography
;
Ultrasonography, Prenatal
8.Detection of proteinase resistant protein from scrapie-affected mice and hamsters.
Yong Sun KIM ; Eun Kyoung CHOI ; Sung Wook YOON ; Yang Suk OH
Journal of the Korean Society of Virology 1992;22(1):91-95
No abstract available.
Animals
;
Cricetinae*
;
Mice*
9.Two Case of Twin Pregnancy with a Single Anomalous Fetus.
Jeong In YANG ; Kie Suk OH ; Haeng Soo KIM ; Eun Joo AHN ; Hyun Hee PARK
Korean Journal of Obstetrics and Gynecology 1999;42(2):420-425
Twin pregnancy is at increased risk for congenital anomalies. Although twins were relatively infrequent, they accaunted for a disproportionately large portion of adverse pregnancy outcome, primarily as a consequence of preterm delivery, gestational diabetes, and pregnancy induced hypertension. In case of twin pregnancy with a single anomalous fetus, the clinicians are faced with difficult decision-making processes regarding the route of delivery, when to deliver, how aggressively to attempt to prevent delivery. Twin pregnancy discordant for a fetal abnormality can be managed expectantly or by selective fetocide of abnormal twin. Recently we experienced two cases of twin pregnancy with a single anornalous fetus. We reported cases with concerned literatures.
Diabetes, Gestational
;
Female
;
Fetus*
;
Humans
;
Hypertension, Pregnancy-Induced
;
Pregnancy
;
Pregnancy Outcome
;
Pregnancy, Twin*
10.Unilateral Congenital Diaphragmatic Eventration Mimicking Congenital Diaphragmatic Hernia.
Jeong In YANG ; Kie Suk OH ; Haeng Soo KIM ; June Seo LEE ; Jeong HONG
Korean Journal of Obstetrics and Gynecology 1999;42(1):171-174
Congenital diaphragmatic eventration is an abnormal elevation of the diaphragm as a result of developmental failure of muscular fibers during the fetal period. Mediastinal shift to the contralateral side may cause significant compression of the affected chest contents resulting in compromised pulmonary function especially when bilaterally involved. The differentiation between congenital diaphragmatic eventration and diaphragmatic hemia is very difficult but eventration has a better perinatal outcome compared to diaphragmatic hernia. We report a case of congenital diaphragmatic eventration on left side with good perinatal outcome after plication in which the initial prenatal diagnosis of diaphragmatic hernia was made by prenatal ultrasonography.
Diaphragm
;
Diaphragmatic Eventration*
;
Hernia, Diaphragmatic*
;
Prenatal Diagnosis
;
Thorax
;
Ultrasonography
;
Ultrasonography, Prenatal