2.Treatment for the Femoral Shaft Fractures in Adolescents.
Hyoun Oh CHO ; Kyung Duk KWAK ; Sung Do CHO ; Il Jong YANG
The Journal of the Korean Orthopaedic Association 1997;32(2):376-383
Treatment for the femoral shaft fractures in adolescents is somewhat controversial. These fractures have been treated nonoperatively, but adolescents tolerate prolonged immobilization less well than younger children and conservative treatment in this age group may result in more complicationssuch as malunion, shortening and angular deformities more often than those in the younger age group. Recently there has been a tendency to choose the operative method rather than traditional traction and casting technique for femoral shaft fractures in elderly children and adolescent The purpose of this study is to find better treatment for the femoral shaft fractures in adolescents. Fifty six femoral shaft fractures in 56 patients aged 10 to 14 years old were treated with traction followed by casting, open reduction and internal fixation with plate, closed intramedullary nailing, or external fixation using A-0 external fixator, and evaluated respectively for at least 1 year. External fixation may be benefit to patients with concomittant injuries and result in psychological settle down, early mobilization out of bed, short hospital stay, save of cost,and early return to daily living activities without any disadvantages such as malunion, leg length discrepancy or awareness of growing arrest in spite of negligible pin tract infection. Result of this study suggests that external fixation for the femoral shaft fractures may be an one of the attractive treatment option in adolescents.
Activities of Daily Living
;
Adolescent*
;
Aged
;
Child
;
Congenital Abnormalities
;
Early Ambulation
;
External Fixators
;
Fracture Fixation, Intramedullary
;
Humans
;
Immobilization
;
Leg
;
Length of Stay
;
Traction
3.Expression of P, type 1 fimbriae, HEp-2 cell adherence, and colonization factor antigens of uropathogenic escherichia coli.
Kyung Sang LEE ; Kyung Hee KIM ; Yang Ja CHO ; Wha Soon CHUNG
Journal of the Korean Society for Microbiology 1993;28(2):105-111
No abstract available.
Colon*
;
Uropathogenic Escherichia coli*
4.Operative Treatment of Thoracolumbar Spine Fractures with AO Internal Fixator
Hyoun Oh CHO ; Kyung Duk KWAK ; Sung Do CHO ; Chul Soo RYOO ; Jong Dae BAEK ; Il Jong YANG
The Journal of the Korean Orthopaedic Association 1995;30(4):926-932
The AO internal fixation system(the Fixateur Interne) is effective in reducing and stablizing a variety of unstable thoracolumbar fracture patterns. It is relatively effective in decompressing the canal of retropulsed bony fragments associated with burst fracture. Sixty-Two patients with unstable thoracolumbar spine fractures were treated with the AO internal fixator. They were followed for an average of 21 months(range 15-29 months). A compartive radiographic analysis of kyphosis and vertebral height was made using pre-operative, post-operative and follow-up radiogram. Changes in neural canal compromise were measured in 18 cases of burst fractures. Failure of instrumentation occured in 9 cases which were carefully analyzed. Recently, we've constructed the system of which the Schanz screws would be directed divergently in sagittal plane in the hope that the load to the screws might be reduced, thus the failure rate.
Follow-Up Studies
;
Hope
;
Humans
;
Internal Fixators
;
Kyphosis
;
Neural Tube
;
Spine
6.A Study of Pure Aortic Valvular Stenosis in Adult.
Yang Koo YUN ; Kyung Jong YOU ; Meyun Shick KANG ; Byung Chul CHANG ; Bum Koo CHO
Korean Circulation Journal 1995;25(6):1183-1188
BACKGROUND: There has been a change in the causes of aortic stenosis when comparence of rheumatioc aortic stenosis in recent year. Therefore, we studied the etiology factor of pure aortic stenosis. METHODS: The gross surgical pathologic features of the aortic valves were reviewed in 92 patients with pure aotic stenosis whom underwent aortic valve replacement at Yonsei University, Cardiovascular center between July 1989 and June 1994. RESULTS: The three most frequent causes were 1) calcification of congenital bicuspid valve in 30%, 2) degenerative calcification of aortic valve in 22%, 3) rheumatioc valvular change in 48%. The mean age at the time of aortic valve replacement for the entire series of patients was 54.4 years. The range of age was from 18 years to 77 years. Males predominated for degenerative disease and congenital bicuspid valves, but there were reversed rheumatic origin. One or more complications occured in 17% of patients undergoing operation. The surgical mortality was 3.3%. CONCLUSION: Our data suggest that more common cause of aortic stenosis is non-rheumatic disease rather than rheumatinc origin.
Adult*
;
Aortic Valve
;
Aortic Valve Stenosis
;
Constriction, Pathologic*
;
Humans
;
Male
;
Mitral Valve
;
Mortality
7.Graft Adhesion and Recovery of Corneal Function after Posterior Lamellar Keratoplasty.
Journal of the Korean Ophthalmological Society 2006;47(7):1100-1109
PURPOSE: Posterior lamella keratoplasty has been described as a new procedure to treat corneal conditions involving endothelial dysfunction by selective transplantation of only the posterior corneal tissue composed of the endothelium, Descemet membrane, and posterior stroma. This study has been conducted to evaluate the recovery of endothelial function and adhesion mechanism of transplanted posterior corneal tissue to the donor stroma after posterior lamella keratoplasty. METHODS: Dog corneal endothelium and posterior stroma were transplanted to recipient dog cornea stripped of endothelium and posterior stroma. The recovery of endothelial function and corneal thickness were measured by specular microscopy; pachymetry and slit lamp examination were done immediately after posterior lamella keratoplasty and at 1, 2, 4, 8 weeks post-operative. Eight weeks after operation, enucleation was performed and the histopathologic changes in the transplanted area of enucleated eyes were examined by light microscopy, fluorescent microscopy, and electron microscopy. RESULTS: Corneal thickness, endothelial function, and corneal transparency were recovered by the end of experiment. The newly produced collagen fibrils were absent at the corneal posterior flap and anterior stromal bed interface. The collagen fibrils adjacent to the flap interface were irregularly arranged and morphologically transformed in some cases (2 of 8 cases) and were linearly arranged in a parallel manner in others (6 of 8 cases). CONCLUSIONS: It can be suggested that the stability of transplanted posterior corneal flap is maintained by incomplete wound healing and recovery of corneal endothelial function.
Animals
;
Collagen
;
Cornea
;
Corneal Transplantation*
;
Descemet Membrane
;
Dogs
;
Endothelium
;
Endothelium, Corneal
;
Humans
;
Microscopy
;
Microscopy, Electron
;
Tissue Donors
;
Transplants*
;
Wound Healing
8.Respiratory Syncytial Virus Infections and Application of Nested Reverse Transcription-Polymerase Chain Reaction.
Kon Hee LEE ; Hae Sun YOON ; Kyu Man KEE ; Kyung Hee KIM ; Yang ja CHO
Journal of the Korean Pediatric Society 1995;38(11):1486-1497
No abstract available.
Respiratory Syncytial Virus Infections*
;
Respiratory Syncytial Viruses*
9.SPARC Expression in Thyroid Follicular Adenomas and Carcinomas.
Chung Yeul KIM ; Seong Jin CHO ; Min Kyung KIM ; Yang Seok CHAE
Korean Journal of Pathology 2000;34(12):1016-1021
SPARC, secreted protein acidic and rich in cysteine, is a extracellular matrix-associated protein implicated in the modulation of cell adhesion, migration, cell cycle regulation, and angiogenesis. SPARC is expressed in fibrocytes and endothelial cells involved in tissue repair and invasive malignant tumors in the gastrointestinal tract, breast, lung, kidney, adrenal cortex, ovary, and brain. This study was aimed to characterize the different expression of SPARC in the thyroid follicular adenomas and follicular carcinomas. Immunohistochemical staining was performed in paraffin-embedded tissues of 25 follicular adenomas and 15 follicular carcinomas of the thyroid gland. Immunohistochemically, SPARC was not expressed in the 19 follicular adenoma and 2 follicular carcinoma but highly expressed in the 6 follicular adenoma and 13 follicular carcinoma. These findings suggest that SPARC is a potential diagnostic marker of follicular carcinoma and is helpful to distinguish follicular carcinoma from follicular adenoma without vascular or capsular invasion.
Adenoma*
;
Adrenal Cortex
;
Brain
;
Breast
;
Cell Adhesion
;
Cell Movement
;
Cysteine
;
Endothelial Cells
;
Female
;
Gastrointestinal Tract
;
Kidney
;
Lung
;
Ovary
;
Thyroid Gland*
10.Adenoid Cystic Carcinoma of the Male Breast: A case report.
Mi Kyung LEE ; In Chul HONG ; Woo Ick YANG ; Sang Ho CHO
Korean Journal of Pathology 1999;33(5):389-392
A 65 year-old male patient presented with a large palpable mass beneath the areola of the right breast for 7 years. The resected breast tissue was almost totally replaced by a round large solid mass (9 6 cm) with a pink-gray to yellow firm, partly nodular cut surface. Microscopically, the tumor revealed the diagnostic biphasic cellular pattern of adenoid cystic carcinoma, which consisted of both cribriform pattern of myoepithelial cells and tubular pattern of epithelial cells. On immunohistochemistry, the tumor revealed immunoreactivities for alpha-smooth muscle actin and S-100 protein in the myoepithelial cells and for AE1/AE3 in the epithelial cells. Mitoses were scarce. Multifocal lymphatic permeation and foci of perineural invasion were also found. Underlying resection margins and overlying skin were invaded by the tumor. We diagnosed this tumor as grade II adenoid cystic carcinoma according to the system utilized for the salivary gland tumors.
Actins
;
Adenoids*
;
Aged
;
Breast*
;
Carcinoma, Adenoid Cystic*
;
Epithelial Cells
;
Humans
;
Immunohistochemistry
;
Male*
;
Mitosis
;
S100 Proteins
;
Salivary Glands
;
Skin