1.A Pathological Review of Pleural Effusion by Immunocytochemical Methods.
Dong Hwan SHIN ; Hee Jeong AHN ; Woo Ick YANG ; In Joon CHOI
Korean Journal of Pathology 1990;24(4):476-481
An unequivocal diagnosis of mesothelioma during life, on the basis of limited biopsy tissue or cytological specimens, is frequently difficult and requires distinction from inflammatory mesothelial hyperplasia on the one hand and secondary neoplasms, especially adenocarcinoma on the other. Although some studies have produced conflicting results, it is generally believed that immunohistochemical methods can aid in this distinction. To obtain comparable and reproducible results, 23 metastatic carcinoma of the pleura and 2 unequivocal malignant epiehtlial mesotheliomas were studied by the peroxidase-antiperoxedase method on paraffin-embedded cell blocks, and commercially available antibodies to carcinoembryonic antigen (CEA), keratin and epithelial membrane antigen (EMA) were used. Nineteen metastaic adenocarcinoma (73%) and two mesotheliomas (100%) reacted with keratin and EMA antibodies. Nineteen matastatic adenocarcinomas (73%) reacted with EMA antibodies. Nineteen metastatic adenocarcinoma (73%) reacted with CEA antibody; no mesotheliomas stained for CEA. Two cases of reactive mesothlial hyperplasia showed positive for keratin, but negative reaction for EMA and CEA. Noen of the antibodies used in this study was specific for mesothelioma, but CEA was found to be the most useful marker for differentiating between mesothelioma and metastatic carcinoma.
Adenocarcinoma
;
Biopsy
;
Neoplasm Metastasis
2.A Pathological Review of Pleural Effusion by Immunocytochemical Methods.
Dong Hwan SHIN ; Hee Jeong AHN ; Woo Ick YANG ; In Joon CHOI
Korean Journal of Pathology 1990;24(4):476-481
An unequivocal diagnosis of mesothelioma during life, on the basis of limited biopsy tissue or cytological specimens, is frequently difficult and requires distinction from inflammatory mesothelial hyperplasia on the one hand and secondary neoplasms, especially adenocarcinoma on the other. Although some studies have produced conflicting results, it is generally believed that immunohistochemical methods can aid in this distinction. To obtain comparable and reproducible results, 23 metastatic carcinoma of the pleura and 2 unequivocal malignant epiehtlial mesotheliomas were studied by the peroxidase-antiperoxedase method on paraffin-embedded cell blocks, and commercially available antibodies to carcinoembryonic antigen (CEA), keratin and epithelial membrane antigen (EMA) were used. Nineteen metastaic adenocarcinoma (73%) and two mesotheliomas (100%) reacted with keratin and EMA antibodies. Nineteen matastatic adenocarcinomas (73%) reacted with EMA antibodies. Nineteen metastatic adenocarcinoma (73%) reacted with CEA antibody; no mesotheliomas stained for CEA. Two cases of reactive mesothlial hyperplasia showed positive for keratin, but negative reaction for EMA and CEA. Noen of the antibodies used in this study was specific for mesothelioma, but CEA was found to be the most useful marker for differentiating between mesothelioma and metastatic carcinoma.
Adenocarcinoma
;
Biopsy
;
Neoplasm Metastasis
3.A clinical analysis of 50 cases of renal transplantation.
Hyung Min JIN ; Chul Woo YANG ; Suk Young KIM ; Chang Joon AHN ; Rae Sung KANG
The Journal of the Korean Society for Transplantation 1993;7(1):95-105
No abstract available.
Kidney Transplantation*
4.A Clinical Review of the HELLP Syndrome.
Sang Tae AHN ; Haeng Soo KIM ; Jeong In YANG ; Joon Hwan OH ; Ki Su HAN ; Seong Cheon YANG ; Kie Suk OH
Korean Journal of Perinatology 2001;12(2):122-130
No abstract available.
Female
;
HELLP Syndrome*
;
Pregnancy
5.Benign proliferative disorders of the breast.
Hee Jeong AHN ; Nam Hoon CHO ; Woo Ick YANG ; In Joon CHOI
Yonsei Medical Journal 1990;31(2):168-173
Fibrocystic disease of the breast has been generally regarded as a disorder due to either excess hormonal stimulation or an exaggerated proliferative response by hypersensitive breast epithelium. The unique lobular lesion-adenosis- and its variants have been regarded as non-neoplastic and non-preneoplastic glandular hypertrophy and hyperplasia, and have different organoid patterns and origins. We have examined a total of 242 cases previously diagnosed as 'fibrocystic disease' at the Department of Pathology with the purpose of clarifying the variants of adenosis in detail and refining the infinitely large 'fibrocystic disease' classification as non-proliferative fibrocystic change and proliferative disorders, such as epitheliosis and atypical hyperplasia. In this study, 224 cases (92.5%) were nonproliferative disease, mostly adenosis (40.1%), and 18 cases (7.5%) were proliferative disease, which consisted of moderate to florid hyperplasia and epitheliosis.
Adult
;
Breast/*pathology
;
Cell Division
;
Female
;
Fibrocystic Disease of Breast/*pathology
;
Fibrosis
;
Human
;
Hyperplasia
;
Retrospective Studies
;
Risk Factors
;
Support, Non-U.S. Gov't
6.Emollient Phototherapy of Pityriasis Lichenoides Chronica.
Kyoung Chan PARK ; Joon Mo YANG ; Kea Jung KIM ; Seung Chul LEE ; Kyu Joong AHN ; Won Suk KIM
Korean Journal of Dermatology 1982;20(1):53-57
Pityriasis lichenoides Chronica is a cutaneous disorder of unknown etiology and characterized pathologically by vasculitis and clinically by its marked chronicity and lack of specific treatment. Emollient-phototherapy is a recently introduced effective treatment for psoriasis. The authors treated 3 patients with pityriasis lichenoides chronica by the emollient-phototherapy technic with quite satisfactory results.
7.Clinical Diversities and Perinatal Outcomes of Nonimmune Hydrops Fetalis.
Suk Joon CHANG ; Haeng Soo KIM ; Jeong In YANG ; Eun Joo AHN ; Young Don LEE ; Kie Suk OH
Korean Journal of Obstetrics and Gynecology 1998;41(7):1927-1933
BACKGROUND: Nonimmune hydrops fetalis has become an important perinatal problem since it was first described in 1943. Although recent advances in antenatal ultrasound have made it possible to detect and manage nonimmune hydrops fetalis in early pregnancy, the perinatal mortality is still high. OBJECTIVE: To obtain clinically useful data regarding antenatal diagnosis, management, and perinatal outcomes of nonimmune hydrops fetalis, and to assist clinicians offer proper antepartum counseling and obstetric management which may be able to improve prognosis. Study design: We retrospectively reviewed 33 cases of nonimmune hydrops fetalis delivered in our hospital over a 4-year period. RESULTS: The antenatal diagnosis was possible by ultrasonography in all cases. Accumulation of fluid in fetal serous cavity and generalized skin edema were observed in all cases. A probable etiology was found in 23 (69.7%) cases through ultrasonography, various laboratory studies including fetal karyotyping, and autopsies. These were cardiovascular (4), respiratory (6), chromosomal (4), skeletal (1), and others (8). Despite extensive diagnostic studies, no definite etiology was found in 10 (30.3%) cases. Excluding the ten fetuses delivered after induced abortion, eight infants were born alive and six died in the neonatal period. The mortality rate was 91.3% (21/23). CONCLUSION: Nonimmune hydrops fetalis represents a very poor perinatal outcome. It is suggested that to improve the prognosis, various antenatal and postnatal approaches to find associated etiologic factors should be performed, and intensive perinatal cares are needed.
Abortion, Induced
;
Autopsy
;
Counseling
;
Edema
;
Female
;
Fetus
;
Humans
;
Hydrops Fetalis*
;
Infant
;
Karyotyping
;
Mortality
;
Perinatal Mortality
;
Pregnancy
;
Prenatal Diagnosis
;
Prognosis
;
Retrospective Studies
;
Skin
;
Ultrasonography
8.Kimura's Disease of The Distal Arm: A Case Report.
Seung Wook YANG ; Seung Joon SHIN ; Mu Ho SONG ; Seong Jun AHN
The Journal of the Korean Orthopaedic Association 2001;36(5):497-500
Kimura's disease is an uncommon, chronic inflammatory disorder of unknown etiology that is seen in an endemic form in the Orient. It usually presents as a mass in the subcutaneous tissue of the head and neck region or the major salivary glands, and is often associated with a regional lymphadenopathy. The patients have peripheral blood eosinophilia and elevated IgE levels but are otherwise usually healthy. We encountered the case of a 33-year-old man who had a soft tissue mass in his left distal arm which was diagnosed as being Kimura's disease.
Adult
;
Arm*
;
Eosinophilia
;
Head
;
Humans
;
Immunoglobulin E
;
Lymphatic Diseases
;
Neck
;
Salivary Glands
;
Subcutaneous Tissue
9.Ruptured Persistent Trigeminal Artery Aneurysm Associated with Moyamoya Disease.
Byung Min YUN ; Jae Sung AHN ; Joon Soo KIM ; Yang KWON ; Byung Duk KWUN
Journal of Korean Neurosurgical Society 2001;30(6):769-773
Moyamoya disease is defined as the development of collateral pathways, associated with bilateral chronic progressive stenosis of the carotid fork. Persistent trigeminal artery is the vessel most frequently observed to persist into adult life among persistent carotid-basilar and carotid-vertebral anastomotic vessels. The authors present a man who had a sudden, severe headache and brain CT showed subarachnoid hemorrhage in left interpeduncular and prepontine cistern. Four-vessel angiogram revealed moyamoya disease associated with aneurysm arising from the junction of persistent trigeminal artery aneurysm and basilar artery. As a treatment, coil embolization was tried but it was failed because of anatomical difficulty of aneurysm. The aneurysm was successfully treated with clipping surgery 10 days later. To our knowledge, this is the first case being reported.
Adult
;
Aneurysm*
;
Arteries*
;
Basilar Artery
;
Brain
;
Constriction, Pathologic
;
Embolization, Therapeutic
;
Headache
;
Humans
;
Moyamoya Disease*
;
Subarachnoid Hemorrhage
10.The Treatment of Traumatic Atlantoaxial Rotatory Subluxation (Fielding Type I) and the Correlation between the Clinical Progress and Radiological Reduction Parameter.
Seong Wan KIM ; Young Joon AHN ; Bo Kyu YANG ; Seung Rim YI ; Seok Jin KIM
Journal of Korean Society of Spine Surgery 2011;18(4):202-207
STUDY DESIGN: This is a retrospective study. OBJECTIVES: We will discuss clinical outcomes of adult traumatic atlantoaxial rotatory subluxation (Fielding type I) and verify the correlation between the clinical outcomes and radiological reduction rate. SUMMARY OF LITERATURE REVIEW: Atlantoaxial rotatory subluxation which usually occur in children by non-traumatic sources or minor trauma has been discussed persistently. However, studies of atlantoaxial rotatory subluxation which occur in adults over 20 years old, especially by traumatic injury is rare. MATERIALS AND METHODS: From October 2004 to April 2011, thirty patients diagnosed of traumatic atlantoaxial rotatory subluxation with 6 months follow-up period were enrolled in the study. After diagnosis, we started treating Halter traction with 5 lbs. We discontinued traction when the patient recovered over 90% of ROM and applied Philadelphia collar to the patient. We measured visual analogue scale (VAS) for cervical pain and ROM. We measured atlanto-dens interval (ADI) and lateral mass-dens interval (LDI) difference using three-dimensional computed tomography (3D-CT) to validate radiological reduction rate. RESULTS: At the end of follow-up, none of the patients complained over pain and all recovered to full ROM. ADI was in normal range during the whole treatment period. LDI difference gradually decreased during treatment period, however, only 8 cases (26.7%) came back to normal range. CONCLUSIONS: In traumatic atlantoaxial rotatory subluxation (Fielding type I), satisfactory clinical outcomes such as pain relief or ROM improvement using traction and the radiological reduction rate was also improved but it failed to achieve a complete reduction of LDI difference in radiography.
Adult
;
Child
;
Follow-Up Studies
;
Humans
;
Neck Pain
;
Philadelphia
;
Porphyrins
;
Reference Values
;
Retrospective Studies
;
Traction