1.Liposarcoma in the Extremity.
Soo Hyun LEE ; In je CHO ; Woo Ick YANG ; Jin Suck SUH ; Kyoo Ho SHIN
The Journal of the Korean Bone and Joint Tumor Society 2010;16(2):62-68
PURPOSE: We analyzed disease free survival and the prognostic factors of liposarcoma in the extremity. MATERIALS AND METHODS: Between 1994 and 2005, of 44 patients who were diagnosed and treated for liposarcoma of the extremity, 40 patients were restrospectively analysed. 13 out of 40 patients got postoperative radiotherapy. We examined local recurrence, distant metastasis and disease free 5-year survival rate. We also analyzed clinical prognostic factors, such as age, gender, size of tumor, prior unplanned excision, histologic type, surgical excision margin and postoperative radiotherapy respectively. RESULTS: There were 3 cases of local recurrence and 4 cases of distant metastasis. The disease free 5-year survival rate was 85.0%. 26 patients presented with myxoid, 8 well differentiated, 4 round cell, 1 pleomorphic and 1 dedifferentiated histology. The disease free 5-year survival rate of mixoid, well differentiated and round cell liposarcoma were 100.0%, 84.6% and 75.0% (p=0.419). The 5-year disease free survival rate was 90.6% in negative surgical margin (n=25) and 62.5% in positive surgical margin (n=15) (p=0.003). CONCLUSION: Our study suggests that surgical excision margin is significant prognostic factor for 5-year disease free survival rate.
Disease-Free Survival
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Extremities
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Humans
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Liposarcoma
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Neoplasm Metastasis
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Recurrence
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Survival Rate
2.Leiomyosarcoma of the penis.
Ji YOO ; Je Jong KIM ; Jae Heung CHO ; Seung Yeon HA ; Yang Seok CHAE
Korean Journal of Urology 1991;32(6):1033-1039
Leiomyosarcoma of the penis is an extremely rare disease. We have encountered a case of leiomyosarcoma of the penis in a 45 year old man. On staging work up. local invasion to corpus cavernosum. but no evidence of lymph node metastasis was evident. After the confirmation of leiomyosarcoma by excisional biopsy, the patient underwent partial penectemy. Herein we report this case with the review of literatures.
Biopsy
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Humans
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Leiomyosarcoma*
;
Lymph Nodes
;
Male
;
Middle Aged
;
Neoplasm Metastasis
;
Penis*
;
Rare Diseases
3.Histiocytosis X with Involvement of Pituitary Stalk: Case Report.
Byung Kyu CHO ; Kyu Chang WANG ; Sei Won YANG ; Je G CHI ; In One KIM ; Kil Soo CHOI
Journal of Korean Neurosurgical Society 1989;18(7-12):1098-1102
A case of histiocytosis X with the involvement of pituitary stalk in a 5 year old boy was described. He presented with diabetes insipidus and the endocrinological study showed growth hormone deficiency. On computerized tomography and magnetic resonance imaging, the pituitary stalk was abnormally thick. Overlooking of the skull lesion on plain X-ray film led to an erroneous diagnosis of germ cell tumor'. Gross total removal of the lesion and chemotherapy were performed. In the differential diagnosis of suprasellar masses, this disease entity should be included. The importance of histological diagnosis of the infundibular lesion in cases of central diabetes insipidus is also emphasized.
Child, Preschool
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Diabetes Insipidus
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Diabetes Insipidus, Neurogenic
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Diagnosis
;
Diagnosis, Differential
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Drug Therapy
;
Germ Cells
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Growth Hormone
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Histiocytosis*
;
Histiocytosis, Langerhans-Cell*
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Humans
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Magnetic Resonance Imaging
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Male
;
Pituitary Gland*
;
Skull
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X-Ray Film
4.Current status of human papillomavirus vaccines.
Kwang Sung KIM ; Shin Ae PARK ; Kyung Nam KO ; Seokjae YI ; Yang Je CHO
Clinical and Experimental Vaccine Research 2014;3(2):168-175
Cervical cancer is a malignant neoplasm arising from cells that originate in the cervix uteri. It is the second most prevalent cancer among women. It can have several causes; an infection with some type of human papillomavirus (HPV) is the greatest risk factor for cervical cancer. Over 100 types of HPVs have been identified, and more than 40 types of HPVs are typically transmitted through sexual contact and infect the anogenital region. Among these, a number of HPVs types, containing types 16 and 18, are classified as "high-risk" HPVs that can cause cervical cancer. The HPVs vaccine prevents infection with certain species of HPVs associated with the development of cervical cancer, genital warts, and some less common cancers. Two HPVs vaccines are currently on the global market: quadrivalent HPVs vaccine and bivalent HPV vaccine that use virus-like particles as a vaccine antigen. This review discusses the current status of HPVs vaccines on the global market, clinical trials, and the future of HPVs vaccine development.
Cervix Uteri
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Condylomata Acuminata
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Female
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Humans
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Papillomavirus Vaccines*
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Risk Factors
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Uterine Cervical Neoplasms
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Vaccines
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Vaccines, Virus-Like Particle
5.Clinical and laboratory characterization of hybrid leukemias.
Seonyang PARK ; Je Hwan LEE ; Sung Hyun YANG ; Myoung Hee PARK ; Nyeong Kook KIM ; Han Ik CHO ; Noe Kyeong KIM
Korean Journal of Hematology 1992;27(2):261-272
No abstract available.
Leukemia*
6.The Effects of Robot-Assisted Rehabilitation on the Gait Ability of Stroke Patients with Hemiplegia: A Mixed Methods Research Study
Min Gyeong PARK ; Yeong Mi HA ; Hyung Je CHO ; Mi Yang JEON
Journal of Korean Biological Nursing Science 2021;23(1):72-82
Purpose:
This study used a mixed methods research design in an attempt to verify the effects of robot-assisted rehabilitation on the gait ability of stroke patients with hemiplegia, and thereby further understand the benefits and challenges of stroke patients’ experiences relying on robot-assisted rehabilitation.
Methods:
An exploratory sequential mixed methods study design was used in order to combine both quantitative and qualitative data. For the quantitative data collection, a total of 30 stroke patients with hemiplegia were recruited from one rehabilitation hospital. Qualitative data were collected through individual interviews using semi-structured questionnaires for a group of 15 patients who were currently undergoing robot-assisted rehabilitation. The data were analyzed through qualitative content analysis.
Results:
As a result of the quantitative analysis, there were significant differences between the two groups in terms of daily living activity patterns, total number of steps, and average walking speed. As a result of the qualitative analysis, the four main themes derived consisted of, ‘curiosity about the usage of robot-assisted rehabilitation,’ ‘pleasure experienced while using the robots,’ ‘insufficient information about robots,’ and ‘a lack of education about robot-assisted rehabilitation.’
Conclusions
Robot-assisted rehabilitation had a significant effect on the walking ability of stroke patients with hemiplegia. Additionally, stroke patients with hemiplegia experienced difficulty during the course of their robot-assisted rehabilitation, due to a lack of sufficient information on correct usage techniques. These quantitative and qualitative findings could provide the basic foundation for the development of an educational program on robot-assisted rehabilitation.
7.Two Cases of Sleep-Related Painful Erection.
Kyoo Ho CHO ; Hye Ihn KIM ; Kyoung HEO ; Yang Je CHO
Journal of Sleep Medicine 2016;13(2):70-73
Sleep-related painful erection (SRPE) is characterized by deep penile pain accompanied with erection occurring rapid eye movement (REM) movement period. Two (47-year-old and 40-year-old, respectively) male visited with the complaint of painful penile erection occurring during sleep. They had no problems with erection during daytime sexual activities except for mild premature ejaculation in one patient. Urologic inspections revealed no focal abnormalities. Polysomnography with simultaneous penile erection monitoring showed several episodes of awakening with painful erection which are time-locked to onset of REM sleep periods. According to the diagnostic criteria in international classification of sleep disorders, each patient was diagnosed to have chronic, severe SRPE. Despite of a low prevalence of SRPE, this condition should be considered in a patient who presents with nocturnal penile. A polysomnography accompanied with penile erection recording may help confirm diagnosis.
Adult
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Classification
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Diagnosis
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Humans
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Male
;
Penile Erection
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Polysomnography
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Premature Ejaculation
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Prevalence
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REM Sleep Parasomnias*
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Sexual Behavior
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Sleep Wake Disorders
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Sleep, REM
8.CD4+T lymphocyte, beta2-microglobulin and p24 antigen level in HIV infected persons.
Yung Kul CHO ; Byung Sun CHO ; Yung Bong KIM ; Koon Je CHO ; Choon KANG ; Sung Soon KIM ; Mi Kyung KI ; Sook Jin HUH ; Tae Sook KIM ; Yang Ja CHO ; Yung Oh SHIN
Korean Journal of Infectious Diseases 1993;25(2):139-149
No abstract available.
HIV*
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Humans
;
Lymphocytes*
9.Management of Alcohol Withdrawal Syndrome and Alcohol Withdrawal Seizure.
Kyoung HEO ; Yang Je CHO ; So Hee EUN ; Sung Chul LIM ; Jeehun LEE ; Pamela SONG
Journal of the Korean Neurological Association 2017;35(3):121-128
Alcohol withdrawal syndrome (AWS) is a common condition occurring after intentional or unintentional abrupt cessation of alcohol in an alcohol-dependent individual. AWS represents a major problem in our society and alcohol withdrawal seizure is the major cause of seizures encountered by neurology residents in the emergency department. Patients with AWS present with mild symptoms of tremulousness and agitation or more severe symptoms including withdrawal seizures and delirium tremens. Particularly, severe AWS can produce significant rates of the morbidity (complications) and mortality. When diagnosed and managed insufficiently, the morbidity and mortality rates increase. Nevertheless, patients with AWS may be neglected and are often marginalized and the teaching about AWS to neurology residents is usually minimal. Also, attending neurologists are often poorly informed on the topic. Although there is insufficient consensus about the optimal investigation and management, the purpose of this review is to serve as a summary of the appropriate identification and management of this important condition in a neurological setting.
Alcohol Withdrawal Delirium
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Alcohol Withdrawal Seizures*
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Consensus
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Dihydroergotamine
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Disease Management
;
Emergency Service, Hospital
;
Humans
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Mortality
;
Neurology
;
Seizures
10.Atypical Unilateral Posterior Reversible Encephalopathy Syndrome Mimicking a Middle Cerebral Artery Infarction.
Ilkay CAMLIDAG ; Yang Je CHO ; Mina PARK ; Seung Koo LEE
Korean Journal of Radiology 2015;16(5):1104-1108
Posterior reversible encephalopathy syndrome (PRES) is usually a reversible clinical and radiological entity associated with typical features on brain MR or CT imaging. However, the not-so-uncommon atypical radiological presentations of the condition are also present and they may go unrecognised as they are confused with other conditions. Here, we report a very rare case of atypical, unilateral PRES in a 49-year-old uremic, post-transplant female patient who presented with seizures. Initial MRI showed high-grade occlusion of the left middle cerebral artery (MCA) and lesions suggestive of subacute infarction in the ipsilateral frontotemporoparietal lobe. Patient symptoms had resolved a day after the onset without any specific treatment but early follow-up CT findings suggested hemorrhagic transformation. Follow-up MRI performed 2 years later showed complete disappearence of the lesions and persisting MCA occlusion.
Acute Kidney Injury/complications
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Brain/radiography
;
Diagnosis, Differential
;
Female
;
Humans
;
Infarction, Middle Cerebral Artery/diagnosis/radiography
;
Lung Transplantation
;
Magnetic Resonance Imaging
;
Middle Aged
;
Posterior Leukoencephalopathy Syndrome/complications/*diagnosis
;
Tomography, X-Ray Computed