No abstract available.
Congenital Abnormalities*

Unilateral nevoid telangiectasia(UNT) is a rare disorder and is characterized by superficial telangiectatic lesions distributed along the dermatomes unilaterally and usually on the upper part of the body. It has been said to be related to increased estrogen receptors in the involved skin. The lesions may be congenital or acquired.Acquired cases are typically associated with physiologic conditions such as pregnancy, puberty, hormonal therapy or cirrhosis, but the condition is also described in alcoholism without cirrhosis, carcinoma metastatic to the liver, and in hepatitis C. We present two cases of UNT in a 26-year-old man with heavy alcoholism and in a puberta1 16-year-old girl.
Adolescent ; Adult ; Alcoholism ; Female ; Fibrosis ; Hepatitis C ; Humans ; Liver ; Pregnancy ; Puberty ; Receptors, Estrogen ; Skin ; Telangiectasis*

No abstract available.
Foot*

The use of intravacular catheterization for both diagnostic and therapeutic purposes increased the incidence of iatrogenic foreign bodies, which might cause many complications such as cardiac arrythmias, perforation of cardiac chamber or blood vessels, sepsis and thromboembolism. The authors experienced 5 cases of successful retrieval of intravascular iatrogenic foreign bodies: three cases of subclavian catheter wire and two cases of subclavian catheter. Subclavian catheter was introduced into right subclavian venous route for hyperalimentation or central venous pressure monitoring. The foreign bodies were located in superior vena cava and inferior vena in four cases and in left main pulmonary artery in the other case. We have successufully removed the foreign bodies by interventional procedures. The loop-snare technique is a safe and effective method for retrieval of iatrogenic foreign bodies in great vessels.
Arrhythmias, Cardiac ; Blood Vessels ; Catheterization ; Catheters ; Central Venous Pressure ; Foreign Bodies* ; Incidence ; Methods ; Pulmonary Artery ; Sepsis ; Thromboembolism ; Vena Cava, Superior

1) This rare case of unilateral bifid ureter can not be found in the literature. 2) It has been located in the left mid ureter and O shaped in its form nominated O shaped bifid ureter by author 3) It is diagnosed on the basis of the IVP and R.G.P..
Ureter* ; Urography*

No abstract available.
Amniocentesis* ; Cerclage, Cervical* ; Female ; Labor Stage, First* ; Pregnancy

This investigation was aimed to study the effect of contrast media on the cardiovascular system. So in thisstudy, pithed rats were used whether alteration in cardiovascular system by contrast media were controlledcentrally. Furthermore, several hypertonic solutions were also used to clarify the effect of contrast media. Theresults are as follows: 1. Intravenous injection of contrast media in rats(2.5m/kg) caused hypotension andbradycardia. The effects were neither blocked by pretreatment of atropine nor pyribenzamine+atropine. 2. NaCl4.7%, dextrose 24.8%, urea 9.0% and glycerol 10.1%(v/v) which were equiosmolar with contrast media, causedhypotension, but did not affect the heart rate. 3. In pithed rats, intravenous injection of Angiografin increasedblood pressure in a dose-dependant manner, and caused decrease in heart rate compared with those of control rats. 4. In pithed rats, bradycardia by intravascular injection with Angiografin was partialy blocked by atropine. 5.Metrizamide of which iodine content was adjusted to 280 mg/ml caused increased in blood pressure when was injectedintravenously in pithed rats with little effect on heart rate. 6. When perfused with contrast media in rathindlimb at 15ml/kg speed both perfusion pressure and flow effluent incereased, simultaneously. These resultssuggest that hypotension might be caused by the central effect due to hyperosmolarity of contrast media andbrachycardia caused by both parasympathetic stimulation and direct inhibitory action on the cardiac conductivesystem.
Animals ; Atropine ; Blood Pressure ; Bradycardia ; Cardiovascular System ; Contrast Media ; Diatrizoate Meglumine ; Glucose ; Glycerol ; Heart Rate ; Hypertonic Solutions ; Hypotension ; Injections, Intravenous ; Iodine ; Perfusion ; Rats ; Urea

The development of inexpensive high throughput methods to identify individual DNA sequences is important to the future growth of medical genetics. This has become increasingly apparent as psychiatric geneticists focus more attention on the molecular basis of complex multifactorial diseases at which most of psychiatric disease is estimated. Furthermore, candidate gene approaches used in identifying disease associated genes necessitate screening large sequence blocks for changes tracking with the disease state. Even after such genes are isolated, large scale mutational analysis will often be needed for risk assessment studies to define the likely medical consequences of carrying a mutated gene. This review provide basic knowledge of up-to-date technology, cDNA microarray which enables above mentioned various research themes.
Base Sequence ; DNA, Complementary* ; Genetics, Medical ; Mass Screening ; Oligonucleotide Array Sequence Analysis* ; Risk Assessment

Progressive zosteriform macular pigmented lesion(PZMPL) is a chronic pigmentary dermatosis similar to progressive cribriform and zosteriform hyperpigmentation(PCZH). This dermatosis described by Simoes in 1980 is characterized by a uniformly tanned macular pigmented lesion in a zosteriform distribution preceded by multiple pruritic macular pigmentation in a part of the dermatome for a period. PZMPL is not a fully understood disease entity but it is thought to be a variant of PCZH. It is differentiated from PCZH by accompanying pruritus as a prodromal symptom, a characteristic clinical course, and histological findings such as pigmentary incontinence. We report herein a case of PZMPL in a 17 year-old girl with the pigmentary skin lesion extending from the left forearm to the left chest along the Blaschkos line. The histological findings revealed increased melanin pigments in the basal layer and focal pigmentary incontinence in the upper dermis. To our knowledge, this case is the first report of PZMPL in korea thought to be the same case reported by Simoes.
Adolescent ; Dermis ; Female ; Forearm ; Humans ; Korea ; Melanins ; Pigmentation ; Prodromal Symptoms ; Pruritus ; Skin ; Skin Diseases ; Thorax ; Triacetoneamine-N-Oxyl

BACKGROUND: Several studies have demonstrated that quantitation of hepatitis B virus (HBV) DNA in sera of HBsAg-positive patients is more useful test for the assessment of infectivity and for the evaluation of disease status than previously utilized numerous serological markers and qualitative polymerase chain reaction for the detection of HBV DNA. We tried to measure serum HBV DNA using a branched DNA (bDNA) signal amplification assay, which is recently introduced and known to be a simple and nonradioisotopic method. METHODS: Total forty patients with HBsAg were randomly selected and serum HBV DNA was measured with duplication using bDNA signal amplification assay (QUANTIPLEXTM HBV DNA ASSAY, Chiron, USA). Quantitation was determined from a standard curve and expressed as HBV DNA equivalents/mL (Eq/mL; 1 Eq = 1 molecule of the primary HBV DNA standard). Serum HBeAg, aspartate aminotransferase (AST), alanine aminotransferase (ALT) , and soluble interleukin-2 receptor (sIL-2R) were compared with HBV DNA. RESULTS: Serum HBV DNA was quantitated in 13 patients (32.5%) (range 6.4x106-7.4x109 Eq/mL, mean 1.8x109 Eq/mL, CV 8.1%). All eleven patients (100%) with both HBsAg and HBeAg an4 2 of 29 patients (6.9%) with HBsAg but not with HBeAg showed measurable HBV DNA (p < 0.001). In addition, serum levels of AST, ALT, and sIL-2R were significantly higher in HBV DNA measured patients compared with those of unmeasured patients. CONCLUSIONS: Above results show that more than half the HBsAg-positive patients do not have enough HBV DNA which is measurable with boNA signal amplification assay but all of HBeAg-positive patients and some of HBeAg-negative patients do. In addition, HBV DNA quantitation might be correlated with the disease activity in HBsAg-positive patients because serum levels of AST, ALT, and sIL-2R are higher in patients measured with HBV DNA than unmeasured.
Alanine Transaminase ; Aspartate Aminotransferases ; Branched DNA Signal Amplification Assay* ; DNA ; Hepatitis B e Antigens ; Hepatitis B Surface Antigens ; Hepatitis B virus* ; Hepatitis B* ; Hepatitis* ; Humans ; Interleukin-2 ; Polymerase Chain Reaction