A case of a 17 years old Korean adolescent who suffered from secondary hydronephrosis and chronic pyelonephritis of the left kidney due to a obstructive adenofibroma, a rare tumor, arising at the ureteropelvic junction of the left renal pelvis was presented.
Adenofibroma* ; Adolescent ; Humans ; Hydronephrosis ; Kidney ; Kidney Pelvis* ; Pyelonephritis

A clinical observation was made on 216 cases of genitourinary tract tumors of the impatients in the Department of Urology, Chosun University Hospital during the 10 years, from January 1972 to December 1981. The results were as follows: 1. During this period, of 1282 cases hospitalized, 216 cases (180 males, 36 females) had tumors of the genitourinary tract, at the rate of 16.8%. 2. The male to female ratio was 5:1 (180:36). 3. The majority of the patients(88.4%) were distributed over age of 40 years. 4. The prostate was the most commonly involved organ (51.3%) and the tumors of the bladder, kidney, testis, penis, pelvis, ureter, urethra were in order. 5. Histopathologically, B.P.H. was observed in 43.1% of all operative tumors, transitional cell carcinoma of bladder in 28.1% and renal cell carcinoma in 5.6%. 6. Operations were performed in 160 patients (74.1%).
Carcinoma, Renal Cell ; Carcinoma, Transitional Cell ; Female ; Humans ; Kidney ; Male ; Pelvis ; Penis ; Prostate ; Testis ; Ureter ; Urethra ; Urinary Bladder ; Urology

Adreno-hepatic fusion is rare condition defined as adhesion of the liver and right adrenal cortex with close intermingling of the respective parenchyme. It is suggested to be an aging phenomenon, because its incidence is much higher in older age group. Clinically it may pose a problem of operability of the organ involved. We report a case of incidentally found adreno-hepatic fusion in a 49 year old female patient with adenocarcinoma of the sigmoid colon. The segementectomy of VIII segement of the liver was done due to a 6 4 cm sized metastatic nodule of adenocarcioma. Pathological examination of the liver revealed an ovoid shaped, 1 0.5 cm sized adrenal cortical tissue. It was subcapsularly located and about 1cm apart from the metastatic adenocarcinoma with an intervening normal hepatic tissue. The adrenal tissue was mainly composed of zona fasciculata without medullary tissue. In the interphase, the adrenal tissue and liver tissue were admixed closely and partially septated by thin fibrous tissue. There was no inflammatory response to the heterotropically located adrenal tissue and there was no symptom related to the adrenal gland.
Adenocarcinoma ; Adrenal Cortex ; Adrenal Glands ; Aging ; Colon, Sigmoid ; Female ; Humans ; Incidence ; Interphase ; Liver ; Middle Aged ; Zona Fasciculata

No abstract available.
Female ; Humans ; Urodynamics* ; Uterine Prolapse*

No abstract available.
Fever* ; Microwaves* ; Perfusion*

Human epithelial cell line immortalized by Ad12-SV40 hybrid virus was transfected with plasmid containing HPV-16 via calcium-phosphate method. Subsequently, 8 clonal cell lines were obtained after G418 selection. Among these clonal cells, clonal cell-4(C-4) and clonal cell-6(G-6) showed increases of tumorigenic cellular properties such as saturation density, soft agar colony formation and cell aggregation. Morphological alteration such as appearane of foci was observed on these two clones after passage 6 and 7(50 to 55 days after transfection). When clonal cells and control cells were treated with MNNG(0.01ug/ml), both C-4 and C-6 showed increases of tumorigenic cellular properties and the level of increase was much more elevated as compared to clonal cells prior to MNNG treatment. Appearance of foci formation was observed in C-4 and C-6 after passage-6. After passage-8, control cells and all clonal cells showed morphological alterations. It seems that treatment of cells containing HPV-16 DNA with MNNG increases tumorigenic properties of the cells and expedite morphological transformations. (continue)
Agar ; Cell Aggregation ; Cell Line ; Clone Cells ; DNA ; Epithelial Cells* ; Human papillomavirus 16 ; Humans* ; Methylnitronitrosoguanidine ; Plasmids

PURPOSE: Benign prostate hyperplasia(BPH) can be treated with alpha1-adrenergic blocker that relaxes prostate smooth muscle or 5 alpha-reductase inhibitor that reduces serum dirtydrotestosterone. The efficacy of the combination of 5 alpha -reductase inhibitor(finasteride) and alpha1-adrenergic blocker(doxazosin) was evaluated in patients with benign prostate hyperplasia. MATERIALS AND METHODS: Eighty five patients with BPH was treated and followed over 6 months and divided into three groups: Group 1(doxazosin 3mg/day), Group 2(finasteride 5mg) and Group 3(combination of both drugs). Initially, all patients were evaluated by international Prostatic Symptom Score(IPSS: irritative, obstructive, sum, life quality), uroflowmetry, residual urine, serum prostate specific antigen(PSA) and prostate weight by transrectal ultrasonography. IPSS, uroflowmetry and complications were evaluated every month. Residual urine and PSA were assessed at every 3 months, prostate weight at every 6 months. RESULTS: In Group 1 and 3, IPSS were more decreased than In Group 2 immediately(p < 0.001). In Group 1 and 3, maximal flow rate was more increased than in group 2 immediately(p < 0.001). There was no difference of mean change of residual urine among three group. In Group 2 and 3, serum prostate specific antigen and prostate weight were more decreased than in Group 1 (p < 0.001). CONCLUSIONS: In medical treatment of BPH, the combination therapy of alpha1-adrenergic blocker and 5alpha-reductase inhibitor shows early symptomatic improvement and decreased prostate weight without significant complications.
Cholestenone 5 alpha-Reductase ; Humans ; Hyperplasia* ; Muscle, Smooth ; Prostate* ; Prostate-Specific Antigen ; Ultrasonography

No abstract available.
Peripheral Nerves* ; Transcutaneous Electric Nerve Stimulation*

PURPOSE: This study was made to evaluate the clinical characteristics and the treatment of the gangrene of the male genitalia manifested with progressive life threatening disease. MATERIALS AND METHODS: Between June 1992 and December 1998, medical records for patients with Fournier's gangrene were reviewed with respect to age at presentation, associated disease, and clinical course and the treatment. RESULTS: The age of patients ranged from 29 to 92 years. The prodromal sign noted were usually low abdominal and inguinal pain. There were no differences in the causative pathogens compared to those of previous reports. The common underlying diseases were diabetes and chronic liver disease. Hypoalbuminemia and leukocytosis were found in all. Early radical debridement and aggressive antibiotics therapy were performed in all cases. Reconstructive surgery of defected skin was performed 7 to 45 days(mean 33.6) after debridement and period of hospital stay ranged from 14 to 123 days(mean 35.8). The motality rate was 13.3%. CONCLUSIONS: It is thought that the motality rate of Fournier`s gangrene is reduced by early aggresseve debridement of the wound and empirical triple antibiotic therapy, and the comprehension of clinical course is important as well.
Anti-Bacterial Agents ; Comprehension ; Debridement ; Fournier Gangrene ; Gangrene* ; Genitalia, Male ; Humans ; Hypoalbuminemia ; Length of Stay ; Leukocytosis ; Liver Diseases ; Male ; Medical Records ; Prodromal Symptoms ; Skin ; Wounds and Injuries

Vesicovaginal fistula is a distressing complication which may follow total hysterectomy, prolonged labor, chemical cauterization due to uterine prolapse. radiation therapy, and cervix cancer. The management of vesicovaginal fistula still remains controversial in regard to the type of approach and timing of repair. A review of experiences with vesicovaginal fistula repair was done on 39 cases admitted to the Department of Urology, Chonnam University Hospital, during the period from January, 1977 to December. 1991. The most prevalent age group was the forties to fifties (25/39 cases, 64.1%). The most common location of vesicovaginal fistula was the trigone (19/39 cases, 48.7%). The highest range of size of vesicovaginal fistula was that below 1.0 cm (24,39 cases, 61.5%).Of 39 cases. 14 occurred after total hysterectomy (35.9%). 13 chemical cauterization (33.3%). 8 prolonged labor(20.5%). 2 radiation therapy (5.1%). 1 Cesarean section (2.6%), and 1 Dilatation & Curettage (2.6%). The success rate of the initial repair was 88.5% (23,26 cases) by transvaginal repair. 83.3% (5/6 cases) by transperineal transvesical repair. 60.0% (3,5 cases) by suprapubic transvesical repair. 100.0% (1/1 case) by colpotleisis, and l00.0% (1/1 case) by ileal conduit, respectively. The transvaginal repair was most simple, and required the least time of average 96 minutes. Of six cases failed in the initial repair, one case was cured with the second repair and two cases with the third repair, with overall cure rate of 92.3% (36/39 cases).
Cautery ; Cesarean Section ; Dilatation and Curettage ; Female ; Humans ; Hysterectomy ; Jeollanam-do ; Pregnancy ; Urinary Diversion ; Urology ; Uterine Cervical Neoplasms ; Uterine Prolapse ; Vesicovaginal Fistula*