1.The Clinical analysis of Acetabular Fracture
Hak Young JEONG ; Seung Wook YANG ; Phill Hoon NAM
The Journal of the Korean Orthopaedic Association 1989;24(5):1384-1394
If the treatment of acetabular fractures are not satisfactory, there will be serious complication such as traumatic arthritis or avascular necrosis of the femoral head. There is much continuing discussion as to where conservative or surgical treatment should be used. The authors experienced 41 cases of acetabular fractures, that wrere treated at the Department of Orthopaedic surgery, Maryknoll Hospital from January 1981 to September 1987. The results of 29 cases who were followed over a 1 year period are as follows:1. According to Letournel's classification, the most common type of elementray fracture was posterior wall(24.1%) and a T- shsped fracture was 10.3 % and both column fractures were 10.3%. 2. Complications were traumatic arthritis(14 cases), superficial infection(5 cases), ectopic ossification(5 cases), osteomyelitis(1 case), AVN of the femoral head(1 case), and iartrogenic femoral shaft fracture(1 case). 3. According to matta's assessment, satisfactory results of conservative treatment were 38% clinically and 38% radiologically, and by surgical treatment, 73% clinically and 64% radiologically. 4. Surgical treatment in acetabular fractures, such as an anatomical reduction and rigid fixation fixation followed by early joint motion were improved the result and decresed the rate of traumatic arthritis.
Acetabulum
;
Arthritis
;
Classification
;
Head
;
Joints
;
Necrosis
2.Lumbar Spinal Instability and Its Radiologic Findings.
Kyoung Hoon YANG ; Nam Kyu KIM ; Young Soo KIM ; Yong KO ; Seong Hoon OH ; Suck Jun OH ; Kwang Myung KIM
Journal of Korean Neurosurgical Society 2000;29(1):78-86
No abstract available.
3.Comparative study of radiologic-pathologic findings of experimental clonorchiasis in rabbits.
Kyung Nam RYU ; Jae Hoon LIM ; You Jung CHO ; Moon Ho YANG
Journal of the Korean Radiological Society 1993;29(1):1-8
Radiological investigation in patients with clonorchiasis is very important as this is the only method of evaluating the severity of clonorchiasis. In order to correlate the radiologic and pathologic findings of clonorchiasis, fourteen rabbits infested with Clonorchis sinensis and five control rabbits were examined radiologically by ultrasonography, computed tomography and cholangiography and the results were correlated with pathologic findings. Dilatation of the intrahepatic small bile ducts of the liver was due to obstruction by flukes: oval or elliptical small filling defects or irregular margin of the bile ducts on cholangiogram or intraluminal echoes on sonogram represented flukes per se; periductal thickening on sonogram and periductal enhancement of bile ducts on CT were due to inflammatory cell infiltration, adenomatous hyperplasia and periductal fibrosis: band like enhancement at the periphery of the liver on CT represented proliferated bile ducts, destruction of liver cells and resultant fibrosis. The study confirmed the pathological bases for the radiological findings of clonorchiasis in liver and bile ducts and will, perhaps, serve as a basis for the future radiologic-pathological correlation of clonorchiasis and in further clinical and experimental researches in the biliary tract diseases.
Bile Ducts
;
Biliary Tract Diseases
;
Cholangiography
;
Clonorchiasis*
;
Clonorchis sinensis
;
Dilatation
;
Fibrosis
;
Humans
;
Hyperplasia
;
Liver
;
Methods
;
Rabbits*
;
Trematoda
;
Ultrasonography
4.Clear Cell Adenocarcinoma of the Urinary Bladder Accompanied by Vesical Endometriosis.
Eun Kyung HAN ; So Yeon PARK ; Nam Hoon CHO ; Woo Ik YANG ; Chanil PARK
Korean Journal of Pathology 1990;24(4):489-496
A case of clear cell adenocarcinoma arising in the female urinary bladder, which is accompanied by endometriosis of the urinary bladder and the uterus, is reported. The carcinoma protruded into the vesical lumen as a fungating mass, and had a tubulocyotic pattern. The tumor cell had intracytoplasmic glycogen and electron microscopically short microvilli on their surface, resembling clear cell acenocarcinoma of the female genital tract including ovary. This is the fourth case report of clear cell adenocarcinoma complicating vesical endometriosis, and may support the view that clear cell carcinome arises from endometriosis which, in turn, from the Mullerian remnant.
Female
;
Humans
;
Adenocarcinoma
5.Clear Cell Adenocarcinoma of the Urinary Bladder Accompanied by Vesical Endometriosis.
Eun Kyung HAN ; So Yeon PARK ; Nam Hoon CHO ; Woo Ik YANG ; Chanil PARK
Korean Journal of Pathology 1990;24(4):489-496
A case of clear cell adenocarcinoma arising in the female urinary bladder, which is accompanied by endometriosis of the urinary bladder and the uterus, is reported. The carcinoma protruded into the vesical lumen as a fungating mass, and had a tubulocyotic pattern. The tumor cell had intracytoplasmic glycogen and electron microscopically short microvilli on their surface, resembling clear cell acenocarcinoma of the female genital tract including ovary. This is the fourth case report of clear cell adenocarcinoma complicating vesical endometriosis, and may support the view that clear cell carcinome arises from endometriosis which, in turn, from the Mullerian remnant.
Female
;
Humans
;
Adenocarcinoma
6.Adjacent Segment Degeneration After Spinal Fusion In Lumbar Degenerative Disorders.
Chang Hoon JEON ; Nam Su CHUNG ; Young Mo YANG ; Nam Hyun KIM ; Yong Chan KIM ; Kyoung Ho KIM
Journal of Korean Society of Spine Surgery 2004;11(4):238-245
STUDY DESIGN: A retrospective radiological assessment was conducted. OBJECTIVES: An attempt to analyze the degenerative change of an intervertebral disc for adjacent segment degeneration in lumbar degenerative diseases. LITERATURE REVIEW SUMMARY: A review of the literature failed to uncover any documented study examining the quantitative analysis of the degenerative change of the intervertebral disc for adjacent segment degeneration. METHODS: This study was based on 45 patients, treated operatively or conservatively at this hospital, between April 1995 and July 2004. 39 and 6 cases of operative and conservative treatments, respectively, were performed. In the 39 operative treatments, there were 34 cases of fusion and 5 of discectomy. Dynamic X-ray and MRI were performed at the initial evaluation, and again more than 2 years later. In the 34 fusion cases, the upper and lower adjacent segments of the fused level were studied, and in the 11 non-fusion cases (conservative treatment or discectomy), the L3-4, L4-5 and L5-S1 level were studied. The instability of the dynamic X-ray and Thompson grade changes of the disc on MRI were also evaluated. Statistical analysis was carried out using the Wilcoxon signed rank test. RESULTS: Adjacent segment degeneration was found in 10 of the 34 cases (29.4%) on plain X-ray. The average Thompson grades of the 33 upper segment cases were 2.6 and 3.4 preoperatively and postoperatively (P=0.000), and for the 24 of the lower segment cases were 2.9and 3.2 (P=0.033), respectively. No statistical increase in the Thompson grade was found in the non-fusion group. CONCLUSIONS: The adjacent discs of the fusion group showed statistically meaningful degeneration on MRI, but this was not correlated with adjacent segment degeneration on plain X-ray. Various anatomical and functional factors must be considered in the evaluation of adjacent segment disease.
Diskectomy
;
Humans
;
Intervertebral Disc
;
Magnetic Resonance Imaging
;
Retrospective Studies
;
Spinal Fusion*
7.Adjacent Segment Degeneration After Spinal Fusion In Lumbar Degenerative Disorders.
Chang Hoon JEON ; Nam Su CHUNG ; Young Mo YANG ; Nam Hyun KIM ; Yong Chan KIM ; Kyoung Ho KIM
Journal of Korean Society of Spine Surgery 2004;11(4):238-245
STUDY DESIGN: A retrospective radiological assessment was conducted. OBJECTIVES: An attempt to analyze the degenerative change of an intervertebral disc for adjacent segment degeneration in lumbar degenerative diseases. LITERATURE REVIEW SUMMARY: A review of the literature failed to uncover any documented study examining the quantitative analysis of the degenerative change of the intervertebral disc for adjacent segment degeneration. METHODS: This study was based on 45 patients, treated operatively or conservatively at this hospital, between April 1995 and July 2004. 39 and 6 cases of operative and conservative treatments, respectively, were performed. In the 39 operative treatments, there were 34 cases of fusion and 5 of discectomy. Dynamic X-ray and MRI were performed at the initial evaluation, and again more than 2 years later. In the 34 fusion cases, the upper and lower adjacent segments of the fused level were studied, and in the 11 non-fusion cases (conservative treatment or discectomy), the L3-4, L4-5 and L5-S1 level were studied. The instability of the dynamic X-ray and Thompson grade changes of the disc on MRI were also evaluated. Statistical analysis was carried out using the Wilcoxon signed rank test. RESULTS: Adjacent segment degeneration was found in 10 of the 34 cases (29.4%) on plain X-ray. The average Thompson grades of the 33 upper segment cases were 2.6 and 3.4 preoperatively and postoperatively (P=0.000), and for the 24 of the lower segment cases were 2.9and 3.2 (P=0.033), respectively. No statistical increase in the Thompson grade was found in the non-fusion group. CONCLUSIONS: The adjacent discs of the fusion group showed statistically meaningful degeneration on MRI, but this was not correlated with adjacent segment degeneration on plain X-ray. Various anatomical and functional factors must be considered in the evaluation of adjacent segment disease.
Diskectomy
;
Humans
;
Intervertebral Disc
;
Magnetic Resonance Imaging
;
Retrospective Studies
;
Spinal Fusion*
8.Immune Reaction of the Vaccinated Hamsters with Combined Hantaan-Puumala Vaccine.
Ho Wang LEE ; Yong Kyu CHU ; Long Zhu CUI ; Young Dae WOO ; Chang Nam AHN ; Hoon KIM ; Yang Seok JANG
Journal of the Korean Society of Virology 1997;27(1):39-47
A large number of viruses belonging to Genus Hantavirus in Family Bunyaviridae are etiologic agents for hemorrhagic fever with renal syndrome (HFRS), or hantavirus pulmonary syndrome (HPS). Hantaan (HTN), Seoul (SEO), Belgrade (BEL), Puumala (PUU) serotype viruses are well known causative agents for HFRS in Eurasian continent. Among those viruses Hantaan and Seoul serotypes are well known to cause HFRS in Korea, but there are some sporadic incidence by other than Hantaan or Seoul viruses. Recently we have developed the combined Hantaan-Puumala virus vaccine to prevent world-wide occurring HFRS. This combined vaccine is formalin inactivated, suckling mouse and suckling hamster brain extracts for Hantaan and Puumala viruses, respectively. Protein contents of this purified candidate vaccine is 27 microgram/ml, which contains 1,024 ELISA antigen units to each virus, but content of myelin basic protein which is causing experimental allergic encephalomyelitis is legs than 0.1 ng/ml. Thirty hamsters were given twice at one month interval intra-muscularly and bled on 30 days after each vaccination from retro-orbital sinus vein. Antibody titers were tested against 5 major serotype viruses, Hantaan, Seoul, Belgrade, Puumala and Sin Nombre viruses by IFA and PRNT. The mean IF antibody titers on 30 days after primary shot were 78.4, 68.8, 68.8, 37.9, and 15.6; mean neutralizing antibody titers were 65.4, 12, 6.1, 65.6 and 0.5 against Hantaan, Seoul, Belgrade, Puumala and Sin Nombre viruses, respectively. The mean IF antibody titers on 30 days after booster shot were 686.9, 567.5, 550.4, 516.3, and 430.9; and neutralizing antibody titers were 710.8, 41.9, 24.3, 409.9, and 1.6 against Hantaan, Seoul, Belgrade, Puumala and Sin Nombre viruses, respectively.
Animals
;
Antibodies, Neutralizing
;
Brain
;
Bunyaviridae
;
Cricetinae*
;
Encephalomyelitis, Autoimmune, Experimental
;
Enzyme-Linked Immunosorbent Assay
;
Formaldehyde
;
Hantavirus
;
Hantavirus Pulmonary Syndrome
;
Hemorrhagic Fever with Renal Syndrome
;
Humans
;
Incidence
;
Korea
;
Leg
;
Mice
;
Myelin Basic Protein
;
Puumala virus
;
Seoul
;
Seoul virus
;
Sin Nombre virus
;
Vaccination
;
Veins
9.The prognostic significance of steroid hormone receptors, bcl-2 and p53 mutation in correlation with clinicopathological prognostic factors in endometrial cancer.
Sang Woon KIM ; Jae Wook KIM ; Eun Gyung CHOI ; Young Tae KIM ; Nam Hoon JO ; Woo Ik YANG
Korean Journal of Obstetrics and Gynecology 2000;43(12):2127-2134
No abstract available.
Endometrial Neoplasms*
;
Female
10.Changes in High Levels of 17 alpha-Hydroxyprogesterone at Neonatal Screening.
Eun Young PARK ; Jin Hyung CHO ; Su Jin LEE ; Seung YANG ; Kwang Nam KIM ; Jeh Hoon SHIN ; Phil Soo OH
Journal of Korean Society of Pediatric Endocrinology 2003;8(2):156-161
PURPOSE:There are some cases of false positive in neonatal screening for congenital adrenal hyperplasia. To understand its significance of the increased 17 alpha-hydroxyprogesterone(17 alpha-OHP) levels in the cases of positive result, we followed its levels during infancy. METHODS:From July 1997 to June 1998, totally 1,730 babies were screened for congenital adrenal hyperplasia(CAH) measuring 17 alpha-hydroxyprogesterone(17 alpha- OHP) using an enzyme immunoassay(EIA) on dried blood spots. In infants of positive result, the radioimmunoassay(RIA) was used measuring 17 alpha-OHP in serum. And we followed up the levels of 17 alpha-OHP during infancy. Cortisol and ACTH were also measured and followed up in the morning simultaneously. RESULTS:No CAH was detected during the study period. With the 13 ng/mL cutoff limit for 17 alpha-OHP before March 1998, the recall rate was 3.09%. With the 20 ng/mL cutoff limit after March 1998, the recall rate was decreased to 1.58%. Follow-up of the high levels of 17 alpha-OHP in positive cases showed a sharply decreased curve according to age. CONCLUSION: In clinically normal neonates, the high levels of 17 alpha-OHP at screening decreased continuously during infancy.
17-alpha-Hydroxyprogesterone*
;
Adrenal Hyperplasia, Congenital
;
Adrenocorticotropic Hormone
;
Follow-Up Studies
;
Humans
;
Hydrocortisone
;
Infant
;
Infant, Newborn
;
Mass Screening
;
Neonatal Screening*