China ; Female ; Humans ; Male ; Population Surveillance ; Tobacco Use Cessation ; methods ; Tobacco Use Disorder ; epidemiology ; prevention & control ; World Health Organization

With the expanding of ultrasonic applications, the development of ultrasonic surgical equipment has become a focus in related fields. Ultrasonic horn system is an important component of surgical equipment,and the horn resonance properties directly affect the technical performance of ultrasonic surgical equipment. In this paper, a number of tuning and matching methods appeared in recent years are discussed, and the advantages and problems are analyzed. On the basis, foreground of the research is prospected.

This paper presents the situation of secrecy management at colleges and universities,and analyzes the reasons for the inadequacy of capability in this aspect.From the perspective of PAEI management roles,we point out the solutions to improve the capability include strengthening leaderships,targeting,building system,managing risks and raising awareness of secrecy.

Objective To investigate the clinical efficacy of stiletto needle acupuncture plus conventional acupuncture in treating cervical vertigo. Method Sixty patients with cervical vertigo were randomly allocated to treatment and control groups. The treatment group of 30 patients received stiletto needle acupuncture plus conventional acupuncture and the control group, conventional acupuncture alone. An assessment was made using the modified Cervical Vertigo Symptom and Function Evaluation Scale in both groups before and after treatment. Result After two courses of treatment, the total efficacy rate was 93.3% in the treatment group and 73.3% in the control group; there was a statistically significant difference between the two groups (P<0.05). There was a statistically significant pre-/post-treatment difference in the symptom score in the two groups and post-treatment difference in the symptom score between the two groups (P<0.01). Conclusion Stiletto needle acupuncture plus conventional acupuncture has a definite therapeutic effect on cervical vertigo. Its therapeutic effect is superior to that of conventional acupuncture alone.

Background and purpose:Aurora-A is a member of serine/threonine kinase family. The abnormal expression of Aurora-A induces tumorigenesis and radioresistance. This study was aimed to investigate the association of Aurora-A with radioresistance. Methods: Capan-1 cells were treated with Aurora-A kinase inhibitor, and then used to test cell proliferation, anchorage independent assay, cell cycle, and cell cycle regulatory proteins. Treated cells were also used to detect cell apoptosis afterγ-irradiation. Results:Cell growth and colony number in soft agar were decreased after treatment with Aurora-A inhibitor. Treatment of cells with Aurora-A inhibitor also down-regulated the expression of Cyclin D1, CDK2 and CDK6 to induce cell cycle arrest at G1/S and G2/M phases, but promoted cell apoptosis afterγ-irradiation. Conclusion:Treatment of pancreatic cancer cells with Aurora-A kinase inhibitor blocks cell proliferation and cell cycle progression, and promotes sensitivity of cells to radiation. Thus, Aurora-A may be used as one of therapeutic targets to increase the sensitivity of pancreatic cancer radiotherapy.

Breast cancer stem cells comprise a sub-population, which enables the capacity for self-renewal and the potentiality for differentiation and high tumorigenicity. Growing evidence suggests that breast cancer stem cells most likely contribute to tumor generation, progression, relapse, metastasis and therapeutic resistance. Herein, the recent advances in breast cancer stem cells were highlighted in this review.

Object To investigate the synthesis of alkaloids by cell suspension cultures of Datura metel L. Methods Cultured cells derived from leaves of D. metel were m aintained in Murashige and Skoog (MS) liquid medium. The effects of different c arbohydrated, different inoculum sizes, and different pH values of medium as aff ecting facters on cell growth and alkaloid formation were studied. Re sults The optimum carbohydrate was sucrose, inoculum size (1.5 - 2. 0 g/L) for fresh weight and initial pH values (5.5-6.0) of the medium were benefit for cell growth and alkaloid synthesis in the suspension cultures. The synthesis of alk aloids was improved when exogenous phenylalanine added to the culture. Conclusion Suspension-cultured cells of D. metel c an be used to synthesize alkaloids.

Objective:To explore diagnostic value of 6min walking test (6MWT) for coronary heart disease (CHD) . Methods :A total of 192 patients suspected of CHD ,including 123 men and 69 women ,who were treated in our hos‐pital ,were selected .After hospitalization ,all patients received 6MWT and coronary angiography (CAG) examina‐tion .With CAG results as the gold standard for diagnosing CHD ,sensitivity ,specificity ,accuracy ,positive predic‐tive value and negative predictive value of 6MWT diagnosing CHD were calculated ,and they were compared be‐tween men and women .Detections of 6WMT among groups of different diseased number of vessels were compared . Results :With CAG results as the standard ,accuracy ,specificity ,sensitivity ,positive predictive value and negative predictive value of 6MWT diagnosing CHD were 71.35% ,80.58% ,60.67% ,72.97% and 70.34% respectively . Compared with female patients ,there were significant rise in accuracy (57.97% vs .77.24% ) ,sensitivity (39.29%vs .70.49% ) ,specificity (70.73% vs .83.87% ) and positive predictive value (47.83% vs .81.13% ) , P<0.05 or<0.01 ,and significant reductions in false positive rate (29.27% vs .16.13% ) and false negative rate (60.71% vs . 29.51% ) in male patients (P<0.05 or <0.01) ,there was no significant difference in negative predictive value be‐tween two groups (P>0.05) .Compared with single - and double -vessel coronary disease ,there was significant rise in true positive rate (43.75% ,54.05% vs .100% ) of triple - or multi -vessel coronary disease diagnosed by 6MWT , P< 0.01 both . Conclusion:The 6min walking test possesses high specificity and sensitivity diagnosing CHD ,and its diagnostic value is higher for male patients and patients with serious condition .Its procedures are sim‐ple with low cost and no damage to patients ,which can be used as adjunctive examination for CHD diagnosis and ex‐tended in clinic .

Objective To explore some features of the sonographic appearance of recurrent and revival pheochromoeytoma (PHEO) in order to get some references in the clinical diagnosis.Methods To compare sonograms of 10 patients with recurrent and revival PHEO with sonograms of 60 cases(contrast group)with unrecurrent and unrevival PHEO in the same period.Results There was significant difference between the two groups and contrast group(G=9.475,P=0.002).However there was no significance in the incidence of malignant PHEO between recurrent and revival one(P>0.05).The echo of tumor:complex echo 2 cases,purely solid hypoecho 5 cases and hffperecho 1 case.Conclusions The tumor with recurrent and revival PHEO could have potential malignancy,the PHEO at the extra-adrenal often showed a phenomenon of recurrence,and the malignant PHEO appeared the multiple character.

Objective To summarize the clinical features of severe fever with thrombocytopenia syndrome(SFTS),to improve the understanding of the disease,and strengthen the prevention and treatment of the disease,thus to improve the survival rate.Methods To analyze the patients with SFTS in our hospital,including their clinical characteristics and treatment methods.Results Of 210 patients,115 cases were mild,95 cases were heavy cases.191 cases were cured and discharged,among them,115 cases were mild,and the others were severe in all cases.The total effective rate was 90.95%,with a total mortality of 19 cases,with a fatality rate of 9.04%.Conclusion SFTS mainly manifested as fever,fatigue,nausea,vomiting,diarrhea.The treatment is mainly symptomatic treatment of early cases can not be identified,can be added with doxycycline.Those have basic disease and poor prognosis often have severe syndromes.White blood cell,platelet count and lactate dehydrogenase are related to the prognosis of the disease.