This article described the current status of problems in quality and safety in TCM industry. It also emphatically discussed the quality and safety control in TCM production process. In addition, this article used the HACCP (Hazard Analysis and Critical Control Points) system to conduct a hazard analysis on TCM production process and determined the critical control points, and carried out the corresponding control measures, with a purpose to realize effective regulation and control of hazard factors and ensure TCM quality and safety.

BACKGROUND: Laser facial skin resurfacing has become a method of treatment for photoaging and pigmentary conditions. Although excellent results can be obtained by high-energy, pulsed carbon dioxide(CO2) laser, significant morbidity exists due to the considerable thermal damage to the skin. The Erbium: Yttrium Aluminum Garnet(Er: YAG) laser, with a wavelength of 2940 nm, is well absorbed in water. This leads to a very small zone of thermal necrosis, compared ta the CO2 laser. OBJECTIVE: The purpose of this study was to evaluate the results of the combined use of the char-free CO2 laser and the Er: YAG laser in the treatment of facial wrinkles. METHODS: Forty-six patients, aged between 30 and 68 years, with facial wrinkles, were evaulated. Two types of resurfacing laser systems were utilized in this study, a high-energy, short-pulsed CO2 laser and a Er: YAG 1aser. Wrinkle improvement was evaulated by the patients satisfaction, clinical improvement, and photographic analysis before and after the resurfacing procedure. RESULTS: Twenty-six of the 46 patients had greater than an 80% improvement, and 19 patients had a 60-80% improvement. Only one patient showed a 50% or less improvement. CONCLUSIONS: The combination of char-free CO2 laser and Er: YAG laser for facial wrinkles is a safe and effective modality for laser skin resurfacing.
Aluminum ; Carbon Dioxide* ; Carbon* ; Erbium* ; Humans ; Lasers, Gas* ; Lasers, Solid-State* ; Necrosis ; Skin ; Water ; Yttrium

Letterer-Siwe disease in an acutely onset, progressive and fatal disorder of RES, usually appears in male children, chareacterized by constitutional signs and extraos-seous lesions. This case occurred in a 18-day-old female showing hepatomegaly, hemorrhagic crusted papular eruptions on the entire body, and abdominal distension. Direct smear of scraping materials from the skin lesion showed numerous histiocytes. Hematologic and other laboratory examinatons showed no abonormalities.
Child ; Female ; Hepatomegaly ; Histiocytes ; Histiocytosis, Langerhans-Cell ; Humans ; Male ; Skin

OBJECTIVE:To establish a method for the content determination of baicalin in Yangyin mixture. METHODS:HPLC was performed on the column of SunFire C18 with mobile phase of methnol-water-phosphoric acid(43∶57∶0.2,V/V/V)at a flow rate of 1.0 ml/min,the detection wavelength was 280 nm, column temperature was 30 ℃,and the volume injection was 10 μl. RESULTS:The linear range of baicalin was 0.055 75-1.115 μg(r=0.999 9);RSDs of precision,stability and reproducibility test were lower than 2%;recovery was 95.39%-98.44%(RSD=1.19%,n=6). CONCLUSIONS:The method is simple,rapid and accurate,and suitable for the content determination of baicalin in Yangyin mixture.

Objective To investigate the correlation between blood pressure variability and variabilities of some feature variables extracted from photoplethysmography (PPG) signal.Methods Continuous blood pressure (BP) and PPG signal were collected simultaneously from 19 healthy subjects under rest and after exercise.Eight feature variables were extracted from the PPG signal.The relationship between the beat-to-beat variability of BP and feature variables extracted from PPG were quantified by calculating Person's correlation coefficient.Results The variability of the amplitude of PPG was highly correlated with systolic BP variability both under rest (0.75) and after exercise (0.76).Meanwhile,the correlations between systolic BP variability and the variability of the time from the trough to the dicrotic north were 0.74(under rest) and 0.78(after exercise).Conclusion The amplitude variability of PPG is highly correlated with systolic BP variability and can be potentially used for monitoring BP variability.

Objective Compared with povidone iodine solution to clean,glutaraldehyde immersion,highpressure steam sterilization of three disinfection methods for dental handpiece sterilization effect.Methods Select the 20 dental clinical used over phone,were randomly divided into A group,B group,C group,D group 5,A group for the control group,only cleaning method did not use any disinfection,B group was 1% Polyvinylpyrrolidone iodine solution,wipe,C group were soaked in 2% glutaraldehyde soluton,D group were treated with high-pressure steam sterilization,after each phone were inoculated with bacteria sample dish,the more monitoring of four groups of bacterial culture.Results A group of bacterial culture for the intensive growth of bacteria,B group had bacterial growth for the(+ ～+ + +),bacterial growth;C group had bacterial culturegrowth was(+ ～ + +),bacterial growth;D group of bacterial culture Growth of(-),no bacterial growth.Conclusion High-pressure steam sterilization was the disinfection of dental handpieces most effective way.

OBJECTIVE:To discuss the role of Chinese materia medica preparations in hospital traditional Chinese medicine work for references of the development of Chinese materia medica preparations in hospital. METHODS: The importance and role of the research & development, preparation and use of hospital Chinese materia medica preparation in the development chain of Chinese medicine were analyzed. RESULTS & CONCLUSION: The research and preparation of hospital Chinese materia medica preparation make up for the deficiency of the industrial production of Chinese materia medica preparations and play a part in the inheritance and innovation of traditional Chinese medicine.

The aim of this study was to investigate the expression of basic fibroblast growth factor (b FGF) and its relationship with tumor microvasogenesis and biological behavior of human renal carcinoma. Gene expression of b FGF was assayed in 20 cases of renal carcinoma tissue using RNA dot blot hybridization. Meanwhile, the protein expression of b FGF and microvasular density (MVD) was assayed in 35 cases of renal carcinoma tissue with immunohistochemical assay. It was found that the expression of b FGF was significantly higher in renal cancer tissue than in normal renal tissue or normal tissue adjacent to the tumor, There was significant correlation between b FGF expression in cancer tissue and clinical stages as well as clinical grades.Similar results were also observed between MVD and b FGF expression in renal cancer tissue. It seemed that b FGF played an important role in angiogenesis in renal carcinoma. Taken together, the results suggest that MVD and the expression of b FGF in renal cancer tissue might be related to the prognosis of renal carcinoma patients.