Objective To assess voice parametric characteristics of normal children in different age?sex?and phonation conditions. Methods Voice data of 240 children were collected and analyzed with Dr. Speech software. Acoustic signal data were measured in three phonation conditions: the lowest modal voice, natural voice, the highest modal voice. Results Perturbations and normalized noise energy from the highest value to the lowest one by one were that of the lowest modal voice, natural voice, the highest modal voice. The sequences of standard deviation of fundamental frequency were that of the highest modal voice, the lowest modal voice, natural voice. Conclusion The voice quality of normal children had distinctive characteristics in different phonation conditions.

Objective To scrutinize the CT features of pulmonary actinomycosis and analysize the causes of misdiagnosis.Methods CT images of eleven patients with pulmonary actinomycosis proved by pathology were retrospectively reviewed.Among them,6 were scanned with additional enhanced CT scan.Results Among the 11 patients,the lesions located in the inferior lobe in 7 patients,and in the superior lobe in 4 patients.The lesions affected two or more pulmonary segments in 9 patients,6 of them involving two lobes.Irregular mass or nodules with necrotic low-attenuation areas were the main signs in all patients,and segmental consolidations were found in 6 patients.Peripherally progressive enhancement was found in all patients with contrast enhanced CT scan.Vicinity pleural thickening was found in 11 patients,while extrapleural fat deposition was found in 6 patients.One case showed erosion of the chest wall and rib.Conclusion Pulmonary actinomycosis is a chronic suppurative granulomatous inflammation,which is often misdiagnosed with neoplasm or other lung disease because of its mass-like performance.The peripherally progressive enhancement on CT has a certain diagnostic value for P\pulmonary actinomycosis.

[Objective]To observe the curative effect of the Tangshen Particle on diabetes.[Methods] ICR mice were induced for diabetes by Alloxan intravenous injection,take Tangshen Particle and Xiaoke pill as the comparison group,observe each group’s glucose,lipid,renal index,urea,creatinine.[Results] The Tangshen Particle was able to decline glucose,lipid,renal index,urea,creatinine on diabetic mice,but the effect on high dose group was most obvious.[Conclusion] Tangshen Particle has good glucose-lowering and lipid-lowering effect on diabetic mice,and it has preventive and therapeutical effects on diabetic nephropathy .

Dermoid cyst is a benign cystic teratoma consisting of 3 germ cell origin tissues with predominant ectodermal origin and most commonly found in the ovary but rare in the scrotum. We reported two cases of intrascrotal dermoid cysts developed in 7 months and 3 years old boys which were confirmed hiatologically. In one case, the cyst developed from the testis and in another from the paratesticular tissue.
Child, Preschool ; Dermoid Cyst* ; Ectoderm ; Female ; Germ Cells ; Humans ; Ovary ; Scrotum ; Teratoma ; Testis

Objective To observe the effect of neoadjuvant chemotherapy combined with tumor cells reduction and postoperative intraperitoneal perfusion chemotherapy on the efficacy and quality of life of ovarian cancer.Methods From October 2010 to October 2013 at the Department of gynecology,Taizhou Municipal Hospital,65 cases of ovarian cancer patients for the treatment of stage Ⅲ and Ⅳ were randomly divided into intervention group (n =32) and control group (n =33).Patients in the intervention group received neoadjuvant chemotherapy after tumor cell reduction cytoreductive surgery and received postoperative intraperitoneal hyperthermic perfusion chemotherapy and conventional surgery after chemotherapy.Patients in the control group received conventional tumor cell cytoreductive surgery plus postoperative chemotherapy.Surgical status,the effectiveness of treatment,and adverse reactions were compared between two groups.Moreover,survival quality score,relapse rate,and mortality differences were compared between two groups.Results For the intervention group,operation status and effective treatment were better than the control group.The proportion of adverse reactions had no significant difference between two groups.Survival quality had no statistically significant difference between before treatment and after receiving treatment.Quality of life in the intervention group was better than that of the control group.Relapse rate,and mortality rate in the intervention group was lower than the control group.Conclusions Accepted neoadjuvant chemotherapy combined with tumor cytoreductive surgery and surgery after intraperitoneal hyperthermic perfusion chemotherapy can improve the effectiveness of treatment of ovarian cancers,and improve the quality of life,with better short-term effect.

Objective:To evaluate fixation effect of intermaxillary fixation screw.Methods:63 cases with mandibular fractures were treated with open reduction,and then internal fixation were managed with intermaxillary fixation using dental arch splint or intermaxillary fixation screw randomly.The operation time,postoperation periodontal index,mouth open degree,occluding relation and fracture healing were compared.Results:There was no significant difference upon occluding relation,fracture healing and mouth open degree under two treatment methods.Compared with dental arch splint fixation method,intermaxillary fixation screw had shorter operation time and better periodontal index.Conclusion:Intermaxillary fixation screw is a good intermaxillary fixation method because of short operation time.Furthermore,it can provide enough traction retention strength and easy to maintain oral hygiene.

Objective:To evaluate the possibility of prevention of Frey's syndrome by reservation and reconstruction of parotid fascia in parotidectomy.Methods:Parotidectomy with parotid fascia reservation and reconstruction was conducted in 31 cases. 12 months-12 years after operation the patients were examined by Minor test.Result:Positive reaction of Minor test was observed in 3 out of the 31 cases(9.67%).Conclusion:A parotidectomy with reservation and reconstruction of parotid fascia can efficiently prevent Frey's syndrome.

Objective To investigate the influence of composite transplantation of two kinds of acellular xeno-dermis (pigskin) and micro-autograft on wound healing. Methods Seventy-two Sprague-Dawley rats with full-thickness skin defect on the back were randomly divided into three groups, and then compositt skin I(acellular dermal xeno-matrix+autologous particulate skin +selective acellular xeno-dermis) was adopted to cover the skin defect in the experimental group I, composite skin II(acellular dermal xeno-matrix+autologous particulate skin + glutaraldehyde xeno-skin) was adopted to cover the skin defect in the experimental group II, and auto-particulate skin was adopted in the control group. The area of wound healing and the rates of wound contraction were calculated.Tissue samples were harvested and examined by means of histology, immunohistochemistry and electron microscopy. Results There were continuous epidermis and basement membrane, and the dermal matrix was a kind of matrix with normal structure and organization of collagen and without any cellular components in selective acellular xeno-dermis. There was full differentiation of epithelium, orderly collagen arrange and basal membrane of the skin could be identified by immunohistochemical stain in compound skin grafting group I. The healing effect of compound skin grafting group I was better than compound skin grafting group II and auto-particulate skin grafting group. Conclusion The composite grafts constructed by selective acellular xeno-dermis (pigskin) could be a potential new type of composite skin substitute for the repair of full-thickness skin defect.

Objective To investigate whether intestinal bacterial translocation in scalded rat with delayed fluid resuscitation (DFR) was partly due to the reduction of the expression of rat defensin (RD), which was the most important defensin in rat intestinal defensin family excreted by Paneth cells. Methods Fifty-six SPF rats were randomized to 3 groups: sham injury group (n=8); early resuscitation (ER) group (n=24), receiving fluid resuscitation immediately after scald (30% TBSA, third degree); delayed resuscitation group (n=24), receiving fluid resuscitation 6 hours after scald. The animals (n=6, at each time point) were sacrificed at 8, 24, 72 hours after injury. The expression of RD-5 in the terminal ileum was determined with PCR technic. Morphological changes in ileal Paneth cells were observed. Quantitative bacterial cultures of mesenteric lymph nodes (MLN), liver, spleen and lung were also done. Results In both ER group and DR group, ileal RD-5 mRNA expression level was significantly increased at 8 hours after injury, and it began to decrease at 24 hours until the end of the experiment, when the level was much lower than that of the sham group. When two experimental groups were compared, RD-5 mRNA expression level was significantly higher at 8 hours and significantly lower at 72 hours in DR group than in ER group. There were no obvious morphological changes in ileal Paneth cells in all 3 groups. Although high incidence of bacterial translocation was observed in both experimental groups, it was significantly higher in DR group than in ER group. Conclusions DFR did not cause Panth cell damage, and RD-5 changes did not contribute to bacterial translocation in 24 hours after DFR, as the increase in RD-5 mRNA might be an innate protective reaction. However, the decrease in RD-5 production at 72 hours may play a role in bacterial transloca- tion.