1.Experiences of premature infants ICU: practices in 8 months
Tingbiao HUANG ; Bin WANG ; Jun YANG
Chinese Journal of Perinatal Medicine 1998;0(02):-
0.05) except for the PIICU group with more peripherally inserted central catheter (PICC)((26.3%) vs 14.4%,Z=-3.404,P0.05). The NICU group has a higher rate of subsequent complication including chronic lung disease(0.6% vs 2.9%,Z=-2.091,(P
2.Risk factors for deep vein thrombosis after total hip arthroplasty
Orthopedic Journal of China 2006;0(13):-
[Objective] To analyze the clinical risk factors for the deep vein thrombosis(DVT)after the total hip arthoplasty(THA).[Methods]Fifty-one THA in 48 patients from February 2007 to July 2007 were evaluated.Color Doppler ultrasonography was used to detect DVT of bilateral lower extremities in all patients before operatioon and at 7 days after operation.Fifteen clinical factors were examined perioperatively in order to analyze their influences on DVT formation after surgery.[Results]Seventeen patients with DVT after operation were discovered through Color Doppler ultrasonic detection,and all of the DVT occurred at the calf intermuscular vein.The incidence of the DVT in all patients was 33.3%,and 41.7% of these DVT patients were asymptomatic.Logistic regression analysis indicated that patients older than 65(OR=116.597),large volume of blood transfusion(OR=1.01)and high level of triglycerides(OR=37.249)were the risk factors for the occurrence of DVT after the THA.[Conclusion]Female,old age,obesity,increase of the level of triglycerides and cholesteral,O blood type,large volume of blood transfusion and patients with diabetes or hypertension raised possibility the occurrence of DVT.Based on this research,it concludes that patients older than 65,large volume of blood transfusion and high level of triglycerides are the risk factors for the occurrence of DVT after the THA,doctors should control the total dose of blood transfusion,to reduce the dose per time and increase the times of massive blood transfusion.Besides these,both clinicians and doctors performing Color Doppler ultrasonography should pay attention to the calf intermuscular DVT.
3.Expressions of PTEN,P27 and TGF-?_1 in cervical adenocarcinoma and their clinical significance
Jun YANG ; Liangdan TANG ; Bin WANG
Journal of Third Military Medical University 1984;0(02):-
0.05).The expression of PTEN was positively correlated to P27 in cervical adenocarcinoma.No obvious relationship of TGF-?1 with PTEN or P27 was found.Conclusion PTEN and P27 are of value in the prognosis of cervical adenocarcinoma.TGF-?1 may not contribute to carcinogenesis and development of cervical adenocarcinoma.
4.Changes and Clinical Significance of Glucose,Insulin and Insulin-Like Growth Factor-1 in Serum of Newborn Infants with Hypixic-Ischemic Encephalopathy
jun-mei, YANG ; jing-bin, CUI ; ji-jun, SONG
Journal of Applied Clinical Pediatrics 2004;0(12):-
Objective To observe the changes and relationships of glucose (Glu),insulin(Ins) ,insulin-like growth factor-1 (IGF-1) in newborn infant with hypixic-ischemic encephalopathy (HIE) and the protective role which Ins,IGF-1 worked on neuron.Methods HIE 50 cases,the quantity of IGF-1 in serum was detected by radioimmunoassay,the quantity of Ins in serum was detected by chemiluminescent immunoassay,the quantity of glucose in serum was detected by the instrument with type of Rokangquan TM accutive.The umbilical vein blood 2 mL were drawn from 20 cases of controls after birth.The indexes were detected by the same methods.Results 1.In acute period,the level of serum IGF-1 reduced obviously in newborn infants with HIE,and Glu increased obviously.There was a negative correlation between IGF-1 and Glu.The changes related with neonate complications.In rehabilited pe riod,the Glu get to normal,the IGF-1 was a little higher than that in acute period.but it still was lower than that of control group.There was negative correlation between IGF-1 and Glu.2.The level of Ins in serum of newborn infants with HIE had no obvious changes compairing with control group in acute period and rehabilited period.It had no relations with Glu,Ins.Conclusions It approves that IGF-1 and Glu in serum of newborn infants with HIE have obviously changed.This result will provide an academic base on treatment of HIE.
5.Fatty Replacement of Pancreas:CT Appearances and Clinical Significance (Report of 3 Cases)
Yingchun LI ; Bin SONG ; Jun XU ; Yang YANG ; Longlin YIN
Chinese Journal of Bases and Clinics in General Surgery 2003;0(06):-
Objective To investigate the CT imaging features of pancreatic fatty replacement and its clinical significance. Methods Three patients with pancreatic fatty replacement detected by CT were retrospectively analyzed. CT examination included plain scan and contrast-enhanced scanning at the arterial and portal venous phases. The shape, size, density, pancreatic lobulation and interlobular spaces, course of the pancreatic duct were carefully observed. The clinic and laboratory data were also analyzed to determine the clinical significance of pancreatic fatty replacement. Results ①Imaging features: Two patients had complete fatty replacement involving the entire pancreas, another one had most fatty replacement sparing the posterior aspect of head and tail. Two patients had regular configuration of pancreas. The size of pancreas was slightly enlarged in 2 patients. Lobular atrophy and widening of interlobular spaces were present in all 3 patients. The pancreatic duct was normal in 3 patients. ②Clinic findings: Chronic diarrhea was present in 3 patients. Two patiens had diabetes (one had chronic cholangitis with choledochal lithiasis), another one had small stone in the common bile duct. Serum lipase was low in 3 patients, of which one had low serum amylase. Conclusion Pancreatic fatty replacement demonstrates certain characteristic CT appearances, and is usually associated with disturbances of both the endocrine and exocrine functions of the pancreas.
6.Tegaserod can resume colonic electricity and motion of visceral hypersensitive rat.
Yuan-Jun YIN ; Bin LV ; Wu-Ming YANG
Chinese Journal of Applied Physiology 2008;24(2):174-183
Animals
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Colon
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physiology
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Female
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Indoles
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pharmacology
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Male
;
Myoelectric Complex, Migrating
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Rats
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Rats, Wistar
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Viscera
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physiology
7.Effect of the area of paries medialis defect on the stability of fracture ends after percutaneous compression plating for femoral intertrochanteric fracture
Bin ZHANG ; Jun CHANG ; Zhigang YANG ; Fenglai YUAN ; Junxing YE
Chinese Journal of Orthopaedic Trauma 2016;18(1):61-65
Objective To analyze the effect of different areas of paries medialis defect of femoral trochanter on the stability of fracture ends after percutaneous compression plating for femoral intertrochanteric fracture.Methods Thirteen preserved cadaveric specimens of adult femur were used in this experiment.The age of death ranged from 30 to 50 years.Oblique osteotomy was conducted under the same condition using a wire saw to create experimental models of fracture of Evans-Jensen type Ⅳ.The ratios of the area of paries medialis defect to the projected area of lesser trochanter in the specimens 1 to 13 were set respectively as 0,10.0%,14.5%,20.2%,23.4%,30.6%,45.8%,56.8%,76.8%,88.7%,99.8%,121.3% and 149.4%.All the fractures were fixated by standard percutaneous compression plating.Cyclic load was applied on each specimen using Instron 2000 universal material tester.A vertical load of 600 N was applied for respectively 1,10,100 and 1,000 times to measure the displacements of proximal and distal fracture ends.Results When the ratio of the area of paries medialis defect to the projected area of lesser trochanter was 30.6%,the average displacements of the proximal and distal ends were 0.14 cm and 0.10 cm.When the ratio was 45.8%,the average displacement of the proximal end was 0.53 cm,278.6% greater than that for 30.6%;the average displacement of the distal end was 0.41 cm,310.0% greater than that for 30.6%.When the ratio was 149.4%,the average displacement of the proximal end was 0.93 cm,564.3% greater than that for 30.6%;the average displacement of the distal end was 0.65 cm,550.0% greater than that for 30.6%.Conclusions When the ratio of the area of paries medialis defect to the projected area of lesser trochanter reaches > 45.8%,the area of paries medialis defect will have a significant effect on the stability of fracture ends after percutaneous compression plating for femoral intertrochanteric fracture.The displacement will increase linearly under the same compression with the increase in defect area.
8.Effect of dexmedetomidine on postoperative analgesia pump dose and effect
Bin JI ; Weiwei KONG ; Yang NAN ; Congcong HUANG ; Jun LI
Chinese Journal of Biochemical Pharmaceutics 2015;(11):89-91
Objective To investigate effect of dexmedetomidine on postoperative analgesia pump dose and effect.Methods 50 cases of patients with abdominal surgery under general anesthesia were selected.According to the postoperative analgesic drugs were divided into control group and experimental group, 25 cases in each group were given corresponding drug treatment.After treatment, the visual analogue scale, comfort score, adverse reaction rate and dosage of analgesic drugs were detected and compared.Results Compared with the control group,the VAS score were lower(P <0.05),the BCS score were higher(P<0.05),the adverse reaction rate were lower(P<0.05),the dosage of analgesic pump were lower(P<0.05). Conclusion Dexmedetomidine can significantly reduce postoperative pain degree of patients, reduce the incidence of adverse reaction, reduce analgesic dosage of the drug pump.
9.Determination of L-Arginine Content in Cefradine for Injection by HPLC
Jiaai YANG ; Hui WU ; Bin QIAN ; Jun ZHANG
China Pharmacy 1991;0(01):-
OBJECTIVE:To establish an HPLC method for the determination of the content of L-arginine in cefradine for injection.METHODS:The chromatographic analysis was carried on LiChrospher Diol column,and the mobile phase was composed of 0.01 mol?L-1 ammonium dihydrogen phosphate buffer solution(adjusted pH to 2.0?0.1 with phosphoric acid)-acetonitrile(25∶75)at a flow rate of 1.0 mL?min-1;the column temperature was 30 ℃;the detection wavelength was 206 nm,and the sample size was 20 ?L.RESULTS:The linear range of L-arginine was 51.2~307.2 ?g?mL-1(r=0.999 9).The average recovery was 100.7%(RSD=0.6%).CONCLUSION:The method is rapid,accurate and simple,and suitable for the determination of L-arginine in cefradine for injection.
10.Investigation and Study of Large-scale Medical Imaging Equipment in Zhenjiang Region
Jun WANG ; Bin ZHU ; Chengfeng CHU ; Yafang YANG ; Shenchu GONG
Chinese Medical Equipment Journal 1989;0(03):-
The current situation of large-scale medical imaging equipment in Zhenjiang region is briefly summarized.Investigation and study are made on DSA,CT and MR of 19 hospitals in Zhenjiang.Data are treated statistically.Suggestions on management and disposition of large scale medical imaging equipment are put forward at last.