1.Study on relationship between posttraumatic stress disorder and nurses′psychological capital
Qiuxia JIN ; Ziwei KE ; Yanfei LU ; Yuxin GE ; Yanyan LI ; Yiqin SUN
Chinese Journal of Practical Nursing 2017;33(9):704-707
Objective To explore the relationship between posttraumatic stress disorder and nurses′ psychological capital. Methods By convenient sampling, totally 550 nurses in 5 first-class upper level general hospitals in Zhejiang province were investigated by the posttraumatic stress disorder (PTSD)Cheeklist-Civilan Version (PCL-C) and Nurses Psychological Capital Questionnaire Revision (NPCQR), and the results were analyzed. Results 18.35%investigated nurses showed a certain degree of PTSD symptoms and 13.71% showed obvious PTSD symptoms. The positive rate was 32.06%.The overall score of nurses′psychological capital was 78.81 ± 16.54, which was in the middle level, and the dimension scores from high to low were self-efficacy (23.80±5.35), hope (23.36±5.24), resilience (19.66 ±4.29), and optimism (11.99 ± 3.21). The nurses′psychological capital had a negative effect on posttraumatic stress disorder (P<0.01). Conclusions Psychological capital of nurses is a negative predictor of PTSD symptoms, which suggested that managers should pay more attention to the development of nurses′psychological capital to reduce and prevent the occurrence of posttraumatic stress disorder,then to improve nursing service quality.
2.Antiarrhythmic peptide AAPl0 prevents ventricular arrhythmia in rabbit LQT2 model
Bodi CHEN ; Xiaoqing QUAN ; Cuntai ZHANG ; Jiagao LU ; Rong BAI ; Nian LIU ; Yanfei RUAN ; Jun KE ; Jin MA ; Liandong LI ; Lei RUAN
Journal of Geriatric Cardiology 2008;5(3):164-168
Background and Objective Increased transmural dispersion of repolarization (TDR) has been shown to contribute toinitiation and maintenance of ventricular arrhythmia in long QT syndromes(LQTS).Intercellular uncoupling through gap junctions isan important mechanism for maintaining TDR in both intact and diseased heart.The present study was to test the hypothesis thatimproving gap junction communication reduces TDR and prevents ventricular arrhythmia in rabbit LQT2 model.Methods Anarterially perfused rabbit left ventricular preparation and E-403 (0.5μmol/L)were used to establish a model of LQT2.Preparationswere randomly assigned to control(n=10),AAP-100nmol/L(n=10),AAP-500nM(n=10)groups.Transmural ECG as well as actionpotentials from both endocardium and epieardium was simultaneously recorded. Resuits In LQT2 model.presence of 500nmol/LAAP10 reduced endocardial action potential and TDR and prevented ventricular arrhythmia comparing with the control and AAP 100nmol/Lgroups(P<0.05).Conclusions The presence of 500 nmol/LAAP10 reduces TDR and prevents ventricular arrhythmia in rabbitventricular model of LOT2.This study suggests a possible role of GJs in TDR in rabbit LQT2 model and indicates a new clinicalapproach to the management of LQTS.
3. Effect of workplace bullying on posttraumatic stress disorder in nursing staff
Yiqin SUN ; Yuxin GE ; Ziwei KE ; Yanyan LI ; Qiuxia JIN ; Yanfei LU
Chinese Journal of Industrial Hygiene and Occupational Diseases 2018;36(1):22-25
Objective:
To investigate the relationship between workplace bullying and posttraumatic stress disorder (PTSD) in nursing staff, and to analyze the role of psychological capital between workplace bullying and PTSD.
Methods:
From December 2014 to June 2015, convenience sampling was used to collect 496 nurses from 5 grade A tertiary hospitals in a province of China. Their workplace bullying, psychological capital, and PTSD status were assessed using the Negative Acts Questionnaire, Psychological Capital Questionnaire, and Posttraumatic Stress Disorder Self-Rating Scale, respectively. The correlation between variables was analyzed using a structural equation model.
Results:
Among these nurses, the scores of negative acts, psychological capital, and PTSD were 37.15±12.83, 78.81±16.54, and 34.56±12.52, respectively. The score on each dimension of negative acts was positively correlated with that on each dimension of PTSD (
4.Correlation between serum CTRP3 and CTRP9 levels and glycolipid metabolism in preeclampsia pregnant women
Lihua PAN ; Feng ZHOU ; Yanfei KE
Journal of Chinese Physician 2020;22(2):233-236,240
Objective To detect the levels of serum fatty factor complement C1q tumor necrosis factor-related protein (CTRP) 3 and CTRP9 in pre-eclampsia (PE) pregnant women,and to analyze their correlations with the levels of glucose metabolism and lipid metabolism indexes.Methods From January 2016 to March 2018,96 pregnant women with mild pre-eclampsia and 90 pregnant women with severe preeclampsia were selected,another 100 healthy pregnant women were selected as control group.The levels of serum CTRP3 and CTRP9 were detected by enzyme linked immunosorbent assay (ELISA);the levels of triglyceride (TG),cholesterol (TC),low density lipoprotein cholesterol (LDL),high density lipoprotein cholesterol (HDL),free fatty acid (FFA),and fasting blood glucose (FPG) were measured by automatic biochemical analyzer;fasting insulin level (FINS) was measured by automatic chemiluminescence instrument.The insulin resistance index (HOMA-IR) was calculated and the differences among the three groups were compared.Pearson was used to analyze the correlation between the levels of CTRP3 and CTRP9 and the indexes of glycolipid metabolism.Results The serum CTRP3 and CTRP9 levels of PE patients in severe group and mild group were significantly lower than those in control group (P < 0.05),and serum CTRP3 and CTRP9 levels in severe PE patients were significantly lower than those in mild PE patients (P < 0.05);the serum lipid metabolism indexes levels of FFA,TG,TC,and LDL of PE patients in severe group and mild group were significantly higher than those in control group (P < 0.05),and HDL level was significantly lower than that of the control group (P < 0.05);the levels of serum lipid metabolism indexes FFA,TG,TC,and LDL of PE patients in severe group were significantly higher than those in mild group (P < 0.05),and the level of HDL was significantly lower than that in mild group (P < 0.05).The levels of serum glucose metabolism indexes FPG,FINS,and HOMA-IR of PE patients in severe group and mild group were significantly higher than those in control group (P < 0.05);the levels of FPG,FINS,and HOMA-IR in severe PE patients were significantly higher than those in mild PE patients (P < 0.05).Pearson test showed that serum CTRP3 and CTRP9 levels in PE patients were negatively correlated with FFA,TG,TC,FPG,FINS,and HOMA-IR levels (P < 0.05),and positively correlated with HDL level (P < 0.05).Conclusions The levels of serum CTRP3 and CTRP9 are decreased in PE patients,which is negatively correlated with FFA,TG,TC,FPG,FINS,and HOMA-IR levels,and positively correlated with HDL level.They may be indirectly involved in the pathogenesis and progression of PE by affecting the glycolipid metabolism in pregnant women.
5.Effects of patient participation -based dietary intervention on nutritional status for patients with severe burns
Ke SHAO ; Juan ZHENG ; Zhimei LIU ; Yanfei LI ; Xiaoting QIU ; Huihui SUN
Chinese Journal of Practical Nursing 2020;36(8):593-597
Objective:To explore the influence of patient participation-based dietary intervention on nutritional status for patients with severe burn.Methods:From September 2017 to January 2019, 60 severe burn patients hospitalized in the department of burn and plastic surgery of Qingdao Municipal Hospital were recruited and divided into the experimental group ( n=30) and the control group ( n=30) according to the random number table method. The control group received a regular diet. While the experimental group received a patient participation-based dietary intervention(PPDI), The wound healing time and the value of nutritional status index, such as height, body mass index(BMI), serum albumin, serum prealbumin, in the two groups on admission, at 2 weeks after intervention, 4 weeks after intervention were compared. The nutritional knowledge questionnaire of burn patients and "3-day diet diary" were used for investigation. Results:The score of nutritional knowledge showed no significant difference between the two groups before intervention. After intervention, the score of nutritional knowledge in the experimental group was 21.40±2.42, significantly higher than that in the control group (19.00±2.26) ( t value was 3.975, P<0.01). For time effect and between-group effect, there were significant difference in serum albumin between two groups ( F values were 9.232, 4.651, P<0.05); the time effect and between-group effect of serum prealbumin were statistically significant ( F values were 11.592, 6.228, P < 0.05). The wound healing time in the experimental group was significantly lower than that in the control group ( t value was -3.801, P<0.01). Conclusions:Patient participation-based dietary intervention can effectively enhanced the level of nutritional knowledge, improved nutritional status, shortened wound healing time among patients with severe burn.