Objective To study the effect of nursing intervention based on quantitative evaluation strategy on treatment effect of elder patients with pulmonary respiratory distress syndrome when received pressure control treatment.Methods 80 cases elder patients with pulmonary respiratory distress syndrome in our hospital were enrolled and randomly divided into the observation group and the control group,there were 40 cases in each group.The observation group received nursing intervention based on quantitative evaluation strategy,while the control group received routine nursing intervention.Then alveolar oxygen function,hemodynamic index,serum inflammatory factor levels and adverse reactions were compared between the two groups.Results ① Alveolar oxygenation function:arterial blood oxygen partial pressure,oxygenation index ratio and arterial blood carbon dioxide partial pressure level in the observation group was (91.61±12.09),(367.34±43.39) and (34.46±5.75) mmHg (1 mmHg=0.133 kPa) respectively,which was significant different than those in the control group respectively,they were (83.33±11.21),(318.34±21.43) and (44.52±5.33) mmHg,P＜0.05.②Hemodynamic index:heart rate central venous pressure in the observation group after the treatment was (95.15±9.02) beats/min and (10.21±2.12) cmH2O (1 cmH2O=0.098 kPa) respectively,which was significant different than those in the control group respectively,they were (99.85±9.15) beats/min and (12.45±2.21) cmH2O,P ＜ 0.05.③Serum inflammatory cytokines:serum interleukin-6,monocyte chemotactic factor protein-1,tumor necrosis factor-α levels in the observation group were lower than those in the control group (118.08±15.32 vs 194.58±22.48) mg/L,(21.54±3.54 vs 39.33±5.43,0.61±0.02 vs 1.41±0.04) μg/L,P＜0.05.④Quantitative evaluation comparison:after treatment,observation group patients with mild was obviously higher than that of before treatment (47.50％ vs.20.00％),severe patients was lower than that before treatment (15.00％ vs 45.00％),x2=10.516,P＜ 0.01.⑤Adverse reactions:observation group adverse reactions was obviously lower than that of control group [7.5％(3/40) vs 25.0％(10/40)],x2=4.501,P ＜ 0.05.Conclusion Nursing intervention based on quantitative evaluation strategy is helpful to improve alveolar oxygenation function,stable hemodynamic indexes,relieve inflammation,reduce adverse reactions.