To discuss long-term changes of refractive status in children after congenital cataract intraocular lens ( lOL) implantation and analyze its related influence factors.METHODS: Seventy cases ( 110 eyes ) with congenital cataract from January 2013 to January 2014 in our hospital were selected, according to the age of patients, they were divided into group A (<2 years old), group B (2~6 years old) , group C ( 7 ~ 12 years old ) . They were all given cataract extraction combined with lOL implantation in congenital cataract. Corneal curvature, axial length, refractive status of three groups after operation were compared, the influence factors ocular axis changes were analyzed. RESULTS: There were no statistically significant differences in corneal curvature of groups A, B, and C after operation ( P>0. 05 );The differences had statistical significances of the corneal curvature of group A after surgery and 3mo after operation (P<0. 05), there were no significant differences of the corneal curvature of group B, group C after surgery and 3mo after operation (P>0. 05);the corneal curvature 3mo after operation of group A was significantly higher than that of groups B and C (P<0. 05), there were no significant differences in the corneal curvature between group B, and group C after 3mo ( P>0. 05 ); There were no statistical significances on axial length after operation in groups A, B, and C (P>0. 05);Ocular axial length difference of group A 3mo after surgery was significantly higher than that of groups B and C ( P < 0. 05 ), ocular axial length had no statistical difference of group B, group c 3mo after surgery ( P>0. 05). Refractive status of three groups after operation showed myopia moving trend, refractive change rate and refractive diopter of group A after operation was significantly higher than that of group B, group C, the difference was statistically significant (P<0. 05). CONCLUSlON: After congenital cataract extraction combined with lOL implantation, patients present myopia refractive state trend. Performance of children below 2 years old is significant. The main factor of myopia is axial growth.

[Objective]To establish a scoring standard of operative risk assessment for the orthopaedic surgery and evaluate the reliability of it.[Method]Anivariable analysis was performed for the preoperative and intraoperative clinical data of 768 patients undergoing orthopaedic surgery from Jan.2001 to Dec.2008,the risk factors associated with orthopaedic surgery were selected.Then multivariable analysis with logistic regression was performed for the selected risk factors.The scoring standard was made through these data.Reliability of the standard was evaluated by predicting of 160 patients in spinal surgery from 2006 to 2008,comparing with the real situation of each operation.[Result]Anivariable analysis showed age,heart function,blood pressure,electrocardiogram,sternum,liver function,renal function,albumin,blood sugar,number of operative variables within four weeks,magnitude,blood loss preoperation,timing of operation were risk factors.[Conclusion]The ORAOS could appropriately predict the occurrence of patients' postoperative complication before operation.

Objective: To investigate the influence of ischemic and pinacidil preconditioning on the activity of NF-?B and its myocardial protective effects.Methods: Eighty isolated rabbit hearts were randomized into five groups(Group C?K?I?P?G).Hearts were removed and mounted in a Langendorff apparatus perfused with 37℃ oxygenated Krebs-Henselet buffer.All groups were subjected to gobal myocardial ischemia for 40 min and reperfusion for 60 min or 120 min.Cardiac functions were monitored at 10 min equilibration ?15 min?30 min?60 min and 120 min reperfusion;Coronary flow(CF) was measured at 10 min equilibration and 30 min reperfusion;Expression of NF-?B P65 was determined at 10 min equilibration?60 min and 120min reperfusion.Results:(1)After ischemic reperfusion,the recovery of cardiac function and CF in Group I and Group P was significantly superior to that in Group C and Group K(P

This paper reports the situation of the treatment for stroke and introduces stroke unit (SU) in overseas hospitals : its important role in the emergency treatment and rehabilitation, the characteristics, advantages and managing modes. Moreover,it discusses the possibility and necessity of establishing SU with characteristics of traditional Chinese medicine.

Education, Professional ; Gastroenterology ; education ; Gastrointestinal Diseases ; surgery ; Humans ; Physicians

ObjectiveTo observe the clinic effect of Xueshuantong in subacute cerebral hemorrhage. Methods60 patients with cerebral hemorrhage were randomly divided into treatment group and control group, each grous 30 cases. The control group, only to conventional treatment, the control group addded Xueshuantong 300mg intravenous drip. On the basis treatment in 7 ～21 days of cerebral hemorrhage both groups were checked the NIHSS score and head CT. Before and after the teatment. ResultsAfter 21days,the hematoma volume in the treatment group was ( 3.3 ± 2. 6) ml, the control group was( 7.2 ± 3.7 ) ml, Treatment group was significantly better than the control group (t =4. 102,P ＜ 0.05 ). NIHSS score of treatment group was (4.7 ± 2.8 ) points, the control group was ( 8.6 ± 3.3 )points. Treatment group was significantly lower than the control group( t =5. 329,P ＜ 0.05). ConclusionXueshuantong could promote the absorption of hematoma and the nerve function recovery in subacute cerebral hemorrhage.

Bronchoalveolar lavage is a lung interventional technique,it has a good prospect in the diagnosis and treatment of childhood respiratory diseases,especially in severe and difficult cases.This article focused on the role of bronchoalveolar lavage in the diagnosis and treatment of respiratory diseases in children,described the impact of pulmonary surfactant.

Objective To investigate the clinical effect of alendronate sodium on bone metabolism and bone mineral density (BMD) for treating the elderly female with osteoporotic distal radius fractures.Methods Ninety elderly female with osteoporotic distal radius fractures patients were divided into treatment group and control group with 45 cases each according to the method of random number list.The two groups were given the medication treatment after 3 d of external fixation stenting.The control group was given calcium dimension D and the treatment group was given alendronate sodium and calcium dimension D.The course of treatment was 6 months.Before and after treatment,the BMD and bone metabolism [bone alkaline pbosphatase(BALP),tartrate-resistant acid phosphatase-5b(TRACP-5b)] were detected in both groups.The wrist function of two groups was evaluated.Results Before treatment,the level of BMD of treatment group and control group were (0.472 ± 0.157),(0.519 ± 0.173) g/cm2,there was no significant difference (P ＞0.05).After treatment,the level of BMD of treatment group and control group were (0.893 ±0.298),(0.571 ± 0.184) g/cm2,the BMD of treatment group after treatment was significantly higher than that before treatment and control group after treatment(P ＜ 0.05).The level of BMD of control group after treatment had no significant difference compared with before treatment (P ＞ 0.05).Before treatment,the level of BALP,TRACP-5b of treatment group and control group were (53.76 ± 17.92),(5.61 ± 1.87) U/L and (51.86 ± 17.29),(5.54 ± 1.85) U/L,the level of BALP,TRACP-5b after treatment had significant difference compared with before treatment and control group after treatment (P ＜0.05).There was no significant difference in control group before treatment and after treatment (P ＞ 0.05).The good rate of rehabilitation of wrist function in treatment group was 91.1％ (41/45),significantly higher than that in control group [51.1％ (23/45)] (x2 =17.524,P ＜0.01).Conclusions The alendronate sodium has a role to suppress bone resorption and increase BMD.It can promote the recovery of wrist function.

Objective To explore the effect of nursing intervention on rehabilitation of stroke patients with hemiplegia.Methods 60 cases of hemiplegic patients after stroke were divided into the control group and the experimental group with 30 cases in each group randomly.The rehabilitation status was evaluated and compared using self rating depression scale (SDS) and activities of daily living (ADL) scale before and after intervention.Results After nursing intervention,ADL score and SDS score were better,treatment effect was also better,but SDS total score showed no significant difference.Conclusions Nursing intervention can effectively reduce or eliminate depression of patients after stroke,strengthen subjective initiative of patients,so that patients can actively cooperate with the treatment,and promote disease rehabilitation.

Objective To analyze the effects of TGF-β1 and p53 on expressions and mutations in smoked lung tissues.Methods Smoked rats model was built.The expressions of TGF-β1 and p53 in lung tissues were observed by immunohistochemistry.The expressions of TGF-β1 mRNA in lung tissues were observed by trans-reverse polymerase chain reaction (RT-PCR).The mutations of p53 in exon 5,6,7-8 were analyzed by polymerase chain reaction single-strandconformational polymorphism (PCR-SSCP).Results The expressions of TGF-β1 in normal lung tissues were faint,and the expressions increased along with the smoking months (P ＜0.05).The positive ratio of protein expression was increased with prolonging smoking time.The mutation of p53 was increased with smoking time.The p53 exons 5,6,7-8 have mutations respectively.The ratio of mutations increased along with smoke months.Conclusion The expressions and mutations of TGF-β1 and p53 increase along with smoked time,which can be regarded as references for lung cancer diagnosis.