Venous thrombotic disease is a serious disease,which impact on health and life-threatening.Pulmonary embolism and deep-vein thrombosis are the two components of a single disease called venous thromboembolism in obstetrics and gynecology.but it can be difficult to diagnose because clinical symptoms and signs are non-specific or absent in early venous thrombus embolism (VTE).It has great value that how to use the most economic,simple,efficient method for screened high-risk groups,timely and accurate laboratory diagnosis of VTE.

ObjectiveTo develop the military acute stress scale and examine the reliability and validity of this scale.MethodsBased upon the previous acute stress researches and the rule of psychometrics,the military acute stress scale was compiled according to open-ended inventory survey.A total of 630 personnel were chosen by random cluster sampling,and tested with this scale,50 of them were tested by Chinese Military psychosomatic health Scale simultaneously,and 50 of them were retested after two week.The reliability and validity were examined by exploratory factor analysis,confirmatory factor analysis and correlation analysis.ResultsThe military acute stress scale was comprised of 9 factors and one lie sub-scale ; Main fit indexes of model were the following CMIN =1219.476,DF =593,P =0.000,CMIN/DF =2.056,IFI =0.927,TLI =0.902,CFI =0.924,RMSEA =0.059; The conrelation coefficients between subscales and subscales were 0.284-0.572.The correlation coefficients between subscales and total scale were 0.700 ～ 0.846 (P ＜ 0.05 or 0.01 ) ; The correlation coefficients was significant between this scale and Chinese military psychosomatic health scale.The correlation coefficients were 0.338-0.962 (P ＜ 0.01 ).The test-retest correlation coefficients of total scale and subscales were 0.379-0.909 (P ＜ 0.01 ).The Cronbaeh's α coefficients were 0.606-0.926 ; and the split-half correlation coefficients were 0.466-0.855.ConclusionThe military acute stress scale has acceptable psychometrics properties on reliability and validity.

Objective:To study the surface enhanced Raman scattering ( SERS) of safflower and identify safflower injections by SERS quickly and effectively. Methods:Through comparative analysis of the Raman spectroscopy of safflower injections and the corre-sponding control herbs, the rapid identification of safflower injections was realized. Results:The results showed that several character-istic peaks of safflower were enhanced obviously in SERS, which could be used to identify safflower injections. Conclusion:The meth-od is reliable, rapid, accurate and specific, which can be applied as a method to identify safflower and its injections.

Objective To observe the effect and safety of different doses of sufentanil plus subarachnoid block during labor. Methods One hundred parturients (single birth) were divided into 5groups by random digits table with 20 cases in each, which sufentanil 3,4,5,6,7 μ g in group A, B, C, D, E plus ropivacaine 3 mg were injected respectively into subarachnoid space. The onset and duration of subarachnoid analgesia were observed; visual analogue scale (VAS) were recorded respectively before injection and 5,15,30,60 min after injection; the vital sign,labor stage,labor type,adverse reactions of parturients,fetal heart rate (FHR) and the Apgar score at 1,5 min of neonate were recorded respectively.Results The onset of subarachnoid analgesia in group A was higher than that in group B,C, D,E;the duration of subarachnoid analgesia in group A,B was shorter than that in group C,D,E.VAS declined gradually 5,15,30,60 min after injection compared with before injection in 5 groups (P ＜ 0.01 );VAS in group B, C, D, E was lower than that in group A at 5 min after injection (P ＜ 0.05 ), and VAS in group C, D, E was lower than that in group A,B at 60 min after injection (P＜ 0.05). There was no significant difference in vital sign,labor stage,labor type,FHR and the Apgar score of neonate among 5 groups (P ＞0.05). The occurrence of itch of skin and nausea in group D,E [25%(5/20), 15%(3/20) in group D,and 40%(8/20),20%(4/20) in group E] was higher than that in group A, B, C [5%(1/20), 0 in group A, 10%(2/20), 0 in group B, 10% (2/20), 0 in group C] (P ＜ 0.05 ). Conclusion Subarachnoid block (sufentanil 4-6 μ g +ropivacaine 3 mg) can offer safety and efficacy of labor analgesia; sufentanil 5 μg is the best dose with subarachnoid block during labor at present.

Objective To investigate the dose-effect relationship of sufentanil combined with dexmedetomidine which used in clinical effectiveness and safety of intravenous analgesia after hip arthroplasty.Methods Sixty patients (after hip arthroplasty) were randomly divided into three groups:group A (sufentanil 0.5 μg/kg),group B (sufentanil 0.75 μg/kg),and group C (sufentanil 1 μg/kg).Each group was combined with dexmedetomidine 1.5 μg/kg in patient controlled analgesia (PCA) pump.Mean arterial pressure (MAP),heart rate (HR),SpO2,numerical rating scale (NRS) scores,and Ramsay sedation scores were recorded at T1 (4 h after operation),T2 (8 h after operation),T3 (24 h after operation),and T4(48 h after operation).Harris hip scores were recorded at T0(preoperative),T3,and T4.The total number of pushing patient controlled intravenous analgesia (PCIA),dezocine dosage,and the occurrence of adverse events in each group situation were recorded.Results There were no significant differences in MAP,HR,and SpO2 among groups.Compared to group A,NRS scores of groups B and C were lower during the analgesia (P ＜0.01).Compared to group A,Ramsay sedation scores of groups B and C were higher at T1,and T2 (P ＜ 0.01).Compared to group A,Harris hip scores of groups B and C were higher at T3,and T4 (P ＜ 0.01).Compared to group C,adverse reactions of groups A and B were less during the analgesia (P ＜ 0.01).Compared to group A,the total number of press PCIA and dezocine amount were decreased in groups B and C (P ＜ 0.01).Conclusions The 0.75 μg/kg sufentanil combined with 1.5 μg/kg right beauty holds the minimum for intravenous analgesia effect after hip arthroplasty and calm exactly satisfied,less adverse reaction,for PCIA ideal drug formula.

OBJECTIVE:To study the pharmacodynamics of Xuanguizhitong drop pill in the treatment of pain caused by Qi-blood Stasis. METHODS: Xuanguizhitong drop pill were prepared into 3 different doses (0.25,0.5, and 1 g?kg-1) with new distilled water. The effects of Xuanguizhitong drop pill at different dose in promoting blood flow, analgesia, anti-inflammatory effect, the ability of anoxia-tolerance at ordinary pressure, and improving the hemorheology indexes in blood stasis model animals were compared. RESULTS: Xuanguizhitong drop pill were remarkable in analgesic, anti-inflammatory and anticoagulant effects and anoxia-tolerance ability at ordinary pressure.The hyperviscosity, thickness, coagulation and accumulation of blood caused by "cold accumulation" in the blood stasis syndrome model rabbits were also improved significantly by Xuanguizhitong drop pill.CONCLUSION:Xuanguizhitong drop pill has remarkable analgesic effect and can promote blood flow to a certain extent.

OBJECTIVE:To evaluate the efficacy of pulmonary surfactan (PS) in the treatment of acute respiratory distress syndrome (ARDS) in infants after undergoing cardio-pulmonary bypass. METHODS: Twenty ADRS infants were randomly assigned to receive routine therapy alone (control group) or routine therapy in combination with PS (trial group). The clinical efficacy in two groups was monitored. RESULTS: In the trial group compared with the control group, the mortality rate was significantly lower(P

Community participation in the rural healthcare service is still necessary under existing Chinese social conditions to achieve the goal of providing general rural public with safe,effective,convenient and inexpensive medical and healthcare services,as is declared in the 17th national people's committee report.The property rights system reform in rural healthcare centers is a reflection of community participation,and related problems in its participation process should be handled by steering the rudder of fairness when the Government applies its functions.The ultimate goal of rural healthcare property rights reform is to achieve the healthcare fairness for every rural individual,and thus right of each participator and fairness in the reform should be ensured.

AIM:To evaluate the economic effectiveness in the treatment of hyperlipoidemia with three kinds of statinsMET_HODS:Using pharmacoeconomical cost-effectiveness analysis,simvastatin,fluvastatin and pravastatin in the treatment of 215 cases of hyperlipoidemia were comparedRESULTS:Fluvastatin was the best kind of statins in lasting treatment for hyperlipoidemiaCONCLUSION:The results show that pharmacoeconomics plays an important role in guiding rational drug use and increasing economic effectiveness

Objective:To observe the effects of radix astragali on hypertrophic scars in rabbit ears. Methods:Twenty healthy adult Japanese big ear rabbits were given hypertrophic scars over the ventral surface of the ears and on the 21st day after wound,animals were randomly divided into the treated groups (groups A,B,and C were treated with radix astragali in different concentrations)and the control groups(groups D and E were treated with saline and blank control,respectively). On the 32nd and 43rd day after wound,the thickness and hardness of scar were measured.The TGF-?1mRNA were detected in hypertrophic scar samples with RT- PCR.The change of scar tissues was observed with H&E staining and immunohistochemical staining with TGF-?1. Results:The thickness and hardness of scar were inversely correlated with the concentration of radix astragali in the radix astragali-treated group(P0.05)between the 32nd day and43rd day groups.Conclusion:Radix astragali could inhibit proliferation of hypertrophic scars in the rabbit ears by decreasing the expression of TGF-?1mRNA and its protein. Thereby radix astragali may have beneficial effects in the treatment of hypertrophic scar.