Through analysis on compliment on drawbacks in medical services in a third - grade hospital during the year of 2003 - 2004, the author gives a picture of the stracture of the medical services today and tells a trend of such compliement goes from service itself security and guatity of the services. Facing the now challenge and charges on compliment today, the anthor holds the idea that establishing 3 new principles, 3 nes reformations and 3 new services to make sure the parients are satisfied.

Humans ; Molecular Epidemiology ; Respiratory Syncytial Virus Infections ; epidemiology ; virology ; Respiratory Syncytial Virus, Human ; genetics

Adolescent ; Child ; Child, Preschool ; Female ; Humans ; Male ; Mucopolysaccharidosis II ; genetics ; Pedigree

Objective To establish a TLC method of identification for Tangfuping Capsule. Methods Mulberry leaf, Ginseng, Bee glue in Tangfuping Capsule were identified by TLC. Results Mulberry leaf, Ginseng, Bee glue in Tangfuping Capsule could be identified by TLC. Conclusion The method is simple and sensitive with strong specificity and reproducibility, and can be used for the quality control of Tangfuping Capsule.

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by memory loss and cognitive decline. The pathological eatures of Alzheimer's disease are abnormal deposition of amyloid beta-peptides (Aβ), neurofibrillary tangles, cholinergic deficits, and loss of synaptic processes and dendritic spines. Senescence accelerated mouse prone 8 exhibits age-related deficits of learning and memory from an early age, tau protein phosphorylation, neurotransmitter changes, synaptic structure and function disorders, circadian rhythm disorders,as well as gene expression and many other characteristic changes, which are consistent with Alzheimer's disease pathological changes，and can be used as an ideal animal model for Alzheimer's disease prevention drugs development.

Fingers ; pathology ; Gangrene ; Humans ; Infant, Newborn ; Infant, Premature ; Male ; Sepsis ; complications ; diagnosis

Adult ; Female ; Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive ; genetics ; Translocation, Genetic

Child ; Female ; Humans ; Job Syndrome

ObjectiveTo investigate the role of the anti-podocyte antibody in the pathogenesis of membranous nephropathy(MN).Methods Thirty-six frozen section slice from biopsies of normal kidney were randomly divided into 3 groups:A,B and C groups(n=12,respectively),then,serum of MN and IgA nephropothy patients,and normal saline were added by drops to frozen section respectively,then the changes were observed by fluorescence microscope.Twenty-one male New Zealand white rabbits were feed with standard diet for 1 week,then were randomly divided into 3 groups:D,E,F groups (n=7,respectively),and injected with the serum of MN and IgA nephropathy,and normal saline respectively through ear-border vein.24-h urinary protein, serumalbumin, serumcreatinineweredetected. Atweek8afterinjection, the histopathological changes in kidney tissue of rabbits were observed by light microscope,electron microscope and immunofluorescence staining. Results Immunofluorescenee staining displayed IgG deposition in glomerular podocytes in group A,and there was no positive expression in other two groups.The quantitative measurement of 24-h urinary protein increased significantly after injection of MN serum (P＜0.01),meanwhile the serum albumin markedly decreased (P＜0.01).The inmnunofluorescence staining showed that IgG deposited in the glomerulus capillaries wall,which presented spherical particles.Light microscope revealed the thickening of GBM without nailing process formation.Electron microscope showed the podocyte foot processes,subepithelial dense deposits.Such pathological changes were not found in E group and F group.Conclusion There is anti-podocyte antibody in blood of MN patients,which may play a role in the pathogenesis of MN.

This paper studies the effect of personnality, motivation, environment, and professional skills on doctor's innovative ability,aimed to provide reference for personnel recruitment and assessment in tertiary hospitals and for improvement of doctors innovative ability. This research was based on a questionnaire that was conducted in 599 doctors from three tertiary hospitals in Guangzhou. The results indicate that four factors affect doctors' innovative ability with different degrees. Relevant measures are suggested