To explore the stability of impact assay for determination of microorganism in indoor air, the comparisons of continued sampling times of 2-minute and 4-minute for monitoring on microorganism of indoor air were carried out with JWL- Ⅱ B multifunctiom air microorganison monitor in 11 hotels, public places of entertainment, barbar shops and beauty shops. The results showed that, under a same environmental condition, there was no significant differences between the data obtained by 2-minute monitoring and 4-minute monitoring (t=1.854, P＞0.05).It indicated that impact assay presented very good stability in detecting the microorganism of indoor air within certaindetecting duration.

Functional gastrointestinal diseases(FGIDs) mainly include functional dyspepsia (FD),irritable bowel syndrome (IBS),functional constipation (FC) and functional abdominal pain syndrome (FAPS).In gastroenterology outpatient,42%～61% FGIDs patients have psychological factors,mostly depression and anxiety.The personality of these patients are almost introvert.Negative life events can be an incentive to lead to depression and anxiety which can aggravate the functional gastrointestinal symptoms.Clinical manifestations include long-term abdominal discomfort,abdominal pain (some with no fixed position),abdominal distension,anorexia,change in bowel habits,retrosternal and upper abdominal burning pain or overlapping symptoms.Some have obvious emotional performance.Dyspepsia symptom score of FD patients with mental disorders are higher than those who have no emotional performance and the gastric emptying decrease greatly than the latter.FGIDs treated by systemic therapy but with no improvement in symptoms may have somatization,compulsion,interpersonal tension,depression,anxiety and other psychological disorders.So psychological evaluation should be carried out to make early recognition for refractory functional gastrointestinal disorders.

TCM has dominance and characteristics in treating chronic nephritis, such as protecting the function of kidney and defering the kidney crocking up. Professor LI Ji-ren, a famous herbalist and the gainer of the special allowance of the State Council, has worked on clinic for 60 years. He Accumulates abundant experiences in treating chronic nephritis. On clinic, Professor Li advocates integratation of syndrome differentiation and disease differentiation, attaching importance to protect the basic of body and flexibility of syndrome differentiation. In aspects of medication, he begins with treating spleen and kidney,at the same time, harmonizing the qi and blood, detaching the clear and dirtiness, protecting other organs. Danbai Zhuanyin Prescription, containing thirteen herbal medicines, has marked effect on chronic nephritis albuminutia.

Objective To discuss the correlation between the expressions of high mobility group protein box 1(HMGB1),VEGF-C/D and lymph node metastasis in colon cancer.Methods Forty-five colon cancer samples were stained by immunohistochemical method for VEGF-C/D,HMGB1.The correlations of VEGF-C/D,HMGB1 expressions and lymph node metastasis were analyzed statistically.Results Positive HMGB1 expression was in 33 specimens,lymph node metastasis was in 27 specimens with 23 specimens of positive HMGB1 and non-lymph node metastasis was in 18 specimens with 10 specimens of positive HMGB1.Positive VEGF-C expression was in 27 specimens with 20 in lymph node metastasis.The expression of HMGB1 was consistent with VEGF-C expression,and HMGB1 and VEGF-C expressions were closely correlated with lymph node metastasis,but not with age,sex,cellular differentiation.Conclusion HMGB1 and VEGF-C expression may become predictor to the prognosis of colon cancer patients.

Objective To discuss the clinical effect on treating hysteromyoma with compound acetic acid gossypol tablets.Methods 50 patients who are diagnosed with hysteromyoma take compound acetic acid gossypol tablets 20mg after supper every day for 3 months. Then Monitor the size of uteruses and tumors of the patients,hemoglobinuria routine、liver function、blood sugar、blood ester、follicle stimu- lating hormone、luteinizing hormone、lactation hormone、progestogen hormone、androsterone hormone using B-ultrasound waves before and after treatment.Results patients will have amenorrhea during treatment and the symptom will disappear.The tumor will dwindle in size by 54.66%(P＜0.01)on average.The Hysteromyoma will dwindle by 50.66%(P＜0.05)on average.Also hemoglobin,Hb returns to nom- al.As a result,the blood sugar and lactation harmone reduce a lot than that before treatment.And other monitoring quality doesnt change obviously.Conclusions There is of great effect using compound acetic acid gossypol tablets to treat hysteromyoma and it has no side effect.It is an available conservative treatment.

"College to undergraduate" education has become the major form of our medical adult education currently in China.However,there still exist a variety of problems and malpractices in this education form,which has hindered its healthy and smooth development.Therefore,it is of high significance for us to figure out a new model for medical adult education.

Objective To explore the effect of pregnancy outcome with cervical cold knife conization in pa -tients with early stage cervical cancer .Methods 23 patients with cold knife conization and 21 patients with radical trachelectomy were collected .The pregnancy outcome and perinatal infants between the two groups were compared . Results The pregnancy rate was 82.6%in the observation group,71.4%in the control group,there was statistically significant difference(χ2 =8.654,P=0.002);the section rate was 37.5% in the observation group,30.8% in the control group,there was statistically significant difference (χ2 =9.645, P =0.000 );10 cases of term delivery (62.5%)and birth weight was(3.27 ±1.15)in the observation group,term delivery(69.2%)and birth weight was (2.81 ±0.96)in the control group,proportion and birth weight were statistically significant differences (χ2 =11.671, P=0.000)(t =9.683,P=0.000);there were statistical significance in the outcome of pregnancy (Fisher P=0.036)and perinatal infants(Fisher P=0.034)among patients with different cervical conization height;the relapse rate was 4.4% in observation group,9.5% in the control group,the relapse rate of the two groups had significant difference(Fisher P =0.039).Conclusion Compared with radical trachelectomy ,patients treated by cold knife conization has high pregnancy rate and high cesarean section rate ,which can influence the outcome of pregnancy and perinatal infants .

Since cancer-related pain is the worldwide problem,intrathecal drug delivery system (IDD)has been an effective pain management option for patients with chronic and cancer pain.Compared with the other ways,such as oral or intravenous infusion,the delivery of drugs into the intrathecal space provides superior analgesia with lower doses of analgesics to minimize side effects while significantly improve quality of life.Recently,besides traditional opioid (especially mainly morphine) for intrathecal,clinical experts have also found some other drugs could be used for IDD to control the cancer-related pain,and have observed their effect and related adverses.This article aims to provide a general overview of the development trend in this field.

Objective To understand cerebral edema and development procedure of different time windows.Methods To analyze their prognosis through image document and operation findings of 52 cerebral trauma patients which were confirmed cerebral edema by CT and operation.Results he light cerebral oedema patients have a better prognosis,10 patients died and 1 patient became a plant man in 11 malignant brain dilatation patients.Conclusion The infernal circle of high brain pressure-cerebral ischemia,cerebral anoxia-cerebral edema result in cerebral edema-brain dilatation-malignant brain dilatation after cerebral trauma which leads to unremitting aggravated pathogenefic condition.So effective means should be used to interrupt the unremitting heightening ICP.