1.Analysis of cervical cancer screening results in 13 297 rural women in Gaoping City
Chinese Journal of Primary Medicine and Pharmacy 2016;23(7):1052-1055
Objective To analyze the results of cervical cancer screening in 13 297 rural women in Gaoping during 2012-2015,and to explore more suitable way for rural women in the examination of cervical cancer.Methods According to theShanxi province rural women cervical cancer check project implementation plan,combined with the actual situation of Gaoping city,the gynecological examination of 13 297 married women in Gaoping city,vaginal and cervical secretions smear, cytology of cervical cytology ( TCT ) , to check the abnormal of the Department of Gynaecology and the abnormal cervical cytology, pathological examination of the cervix of the uterus with abnormal vaginal examination.Results A total of 6 965 cases of infection of the reproductive tract were examined, the prevalence rate was 52.38%.Among them,4 968 cases of cervicitis (37.36%),849 cases of trichomonas vaginitis (6.38%),Candida albicans vaginitis in 988 cases (7.43%),bacterial vaginal disease in 1 364 cases (10.26%), pelvic inflammatory disease in 1 348 cases (10.14%).Cervical cytology examination of ASC -US and the above cases in 418 cases (3.14%),ASC-US examination rate was 1.78%,the rate of ASC-H was 0.28%,the rate of LSIL was 0.60%,and the rate of HSIL was 0.47%.Detection of cervical precancerous lesions and cervical cancer cases,among them CIN I 81 cases,the incidence rate was 609.16/10 million,CIN II 29 cases,incidence rate was 218.09/10 million,16 cases of CIN,incidence rate was 120.33/10 million.The detection rate of precancerous lesions was 338.42/10 million.Cervical carcinoma in situ:1 case,9 cases of invasive cervical cancer,the detection rate of cervical cancer was 75.20/10 million.Conclusion Cervical cancer screening is helpful to improve the early detection rate of cervical cancer in rural women,safeguarding women's reproductive health.At the same time to carry out the census,vigorously promote health knowledge is also very important.
2.The bioethics and the international law:look back and unification
Chinese Medical Ethics 1995;0(02):-
Looking back to the history of the 20th century contributes to the rise of bioethics and the unification of international law on the present age.In the times of rapid scientific and economic development,it is either a core issue of bioethics or a starting point of international law that how humans should survive and establish a relationship with the nature.And a series of common behavior criteria for human being are being or will being established to seek a co-existent path between peoples as well as between human being and nature.
3.Clinical Application of Medical lnformed Consent Series
Chinese Medical Ethics 1995;0(02):-
Medical lnformed Consent(MIC) is a new rule in health care practice.It is required in the Guideline of Medical Record ,which is enacted by National Ministry of Health.Our hospital puts ephasis on Medical Informed Consent Document,modify and apply it into clinical practice by improving understanding.
4.Preparation of 4-Paramisan Sodium Colon-specific Delivery Coated Tablets and the Determination of Its Drug-releasing Rate
China Pharmacy 2005;0(16):-
0.05).CONCLUSION:4-paramisan sodium oral colon-specific delivery coated tablets coated in turn with permeable and enteric soluble acrylic resin has ideal specific delivery and slow-release properties,the coating technology was stable and the reproducibility is good.
5.One case of phenol burn.
Chinese Journal of Industrial Hygiene and Occupational Diseases 2015;33(12):923-923
6.Molecular targeted agents--where we are and where we are going.
Chinese Journal of Cancer 2013;32(5):225-232
A total of 23 new cancer medicines or indication expansions were approved by the U. S. Food and Drug Administration in 2012. Among these, 12 are new molecular entities (NMEs)--new chemical or biological drugs approved for the first time for oncologic use--and 10 of these NMEs are molecular targeted agents. Among the 10 targeted agents, 4 are anti-angiogenesis agents and 2 are Bcr-Abl pathway inhibitors, targeting well established targets validated by previously approved agents such as bevacizumab (Avastin) or imatinib (Gleevec). Despite this progress, several questions remain: Do these newly approved agents provide sufficient treatment options to manage the broad spectrum of cancers we deal with in the clinic? Where will the next wave of new cancer drugs come from? Where should R&D efforts be invested to continue improve cancer treatment and management, especially for tumor types uniquely prevalent in China? This editorial and the review articles in this special issue of Chinese Journal of Cancer provide an in depth review of the progress and challenges in developing targeted cancer therapies, as well as an outlook of new research areas where near term breakthroughs are expected to overcome some of these challenges.
Angiogenesis Inhibitors
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therapeutic use
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Antineoplastic Agents
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therapeutic use
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China
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Drug Delivery Systems
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Drug Discovery
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Humans
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Immunotherapy
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Molecular Targeted Therapy
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Neoplasms
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therapy
7.The treatment of stress gastric ulcer by colded sodium bicarbonate solution infusion
Chinese Journal of Primary Medicine and Pharmacy 2010;17(10):1323-1324
Objective To explore the treatment measures of gastric mucosal damage caused by gastric acid and ischemia after cerebral trauma. Methods 0 ~5 ℃ colded 5% Sodium Bicarboante solution 250 ml were infused into stomach through nasal gastric tube once and remained at least 30 minutes. Results The total effective rate was 100%. Among them,22 cases(73% )bleeding was stopped by once infusion,8 cases died(27% ) ,but the causes of . the death had no direct relation with IGU. Conclusions The result of the method was definite, satisfied, economical and easy to perform and without sideeffects. It should be the best choice for treating IGU.
8.Progress procedure of cerebral edema and clinical analysis of 52 cerebral trauma patients
Chinese Journal of Primary Medicine and Pharmacy 2012;19(14):2114-2115
Objective To understand cerebral edema and development procedure of different time windows.Methods To analyze their prognosis through image document and operation findings of 52 cerebral trauma patients which were confirmed cerebral edema by CT and operation.Results he light cerebral oedema patients have a better prognosis,10 patients died and 1 patient became a plant man in 11 malignant brain dilatation patients.Conclusion The infernal circle of high brain pressure-cerebral ischemia,cerebral anoxia-cerebral edema result in cerebral edema-brain dilatation-malignant brain dilatation after cerebral trauma which leads to unremitting aggravated pathogenefic condition.So effective means should be used to interrupt the unremitting heightening ICP.
9.Analysis of pregnancy outcome in patients with cervical cancer after cervical cold knife conization
Chinese Journal of Primary Medicine and Pharmacy 2014;(9):1349-1350
Objective To explore the effect of pregnancy outcome with cervical cold knife conization in pa -tients with early stage cervical cancer .Methods 23 patients with cold knife conization and 21 patients with radical trachelectomy were collected .The pregnancy outcome and perinatal infants between the two groups were compared . Results The pregnancy rate was 82.6%in the observation group,71.4%in the control group,there was statistically significant difference(χ2 =8.654,P=0.002);the section rate was 37.5% in the observation group,30.8% in the control group,there was statistically significant difference (χ2 =9.645, P =0.000 );10 cases of term delivery (62.5%)and birth weight was(3.27 ±1.15)in the observation group,term delivery(69.2%)and birth weight was (2.81 ±0.96)in the control group,proportion and birth weight were statistically significant differences (χ2 =11.671, P=0.000)(t =9.683,P=0.000);there were statistical significance in the outcome of pregnancy (Fisher P=0.036)and perinatal infants(Fisher P=0.034)among patients with different cervical conization height;the relapse rate was 4.4% in observation group,9.5% in the control group,the relapse rate of the two groups had significant difference(Fisher P =0.039).Conclusion Compared with radical trachelectomy ,patients treated by cold knife conization has high pregnancy rate and high cesarean section rate ,which can influence the outcome of pregnancy and perinatal infants .
10.Research progress of Twist gene in breast cancer
Cancer Research and Clinic 2012;24(8):567-569
There are multiple genes involved in the progress of evolution in breast cancer.Recent study showed that Twist gene may play key role in promoting tumor growth,invasion and metastasis through the epithelial-mesenchymal transition (EMT).Other studies also demonstrated that Twist gene expression maybe associated with patient outcomes and guiding clinical tailored therapies.