1.Effect of different nursing models to improve the quality of sleep for elderly patients in department of cardiology
Chinese Journal of Practical Nursing 2012;28(8):3-5
ObjectiveTo explore the effect of different nursing models to improve the quality of sleep for elderly patients in department of cardiology.Methods240 cases of patients in department of cardiology in our hospital were randomly divided into the control group and the observation group with 120 patients in each group.The control group was given conventional medical care and the sleep-related health education.While the observation group was given the targeted intervention measures based on the control group,including the provision of good psychological care measures to ensure a good sleep environment,arrange a reasonable sleep time,increase bedtime benign behavior and scientific education of hypnotic drugs knowledge.The PSQI score and sleep quality of different time points were compared.ResultsThe PSQI score of the observation group 1 week and 2 weeks after admission was significantly decreased compared with that upon admission,and was better than those of the control group.The PSQI score of the control group 2 weeks after admission had a marked decline,but the PSQI score 1 week after admission showed no significant difference.In the aspect of sleep quality,the rate of good sleep quality for the observation group 1 week and 2 weeks after admission increased significantly compared with that upon admission.The rate of the quality of good sleep 2 weeks after admission for the control group improved significantly than admission.The rate of promotion for the observation group was obviously better than that of the control group.ConclusionsThe targeted quality of sleep and psychological care interventions for elderly patients in department of cardiology can significantly improve the sleep quality in patients after admission,and enhance their confidence in overcoming the disease,thus contribute to disease treatment and rehabilitation.
2.Progress procedure of cerebral edema and clinical analysis of 52 cerebral trauma patients
Chinese Journal of Primary Medicine and Pharmacy 2012;19(14):2114-2115
Objective To understand cerebral edema and development procedure of different time windows.Methods To analyze their prognosis through image document and operation findings of 52 cerebral trauma patients which were confirmed cerebral edema by CT and operation.Results he light cerebral oedema patients have a better prognosis,10 patients died and 1 patient became a plant man in 11 malignant brain dilatation patients.Conclusion The infernal circle of high brain pressure-cerebral ischemia,cerebral anoxia-cerebral edema result in cerebral edema-brain dilatation-malignant brain dilatation after cerebral trauma which leads to unremitting aggravated pathogenefic condition.So effective means should be used to interrupt the unremitting heightening ICP.
3.Research progress of Twist gene in breast cancer
Cancer Research and Clinic 2012;24(8):567-569
There are multiple genes involved in the progress of evolution in breast cancer.Recent study showed that Twist gene may play key role in promoting tumor growth,invasion and metastasis through the epithelial-mesenchymal transition (EMT).Other studies also demonstrated that Twist gene expression maybe associated with patient outcomes and guiding clinical tailored therapies.
4.Clinical analysis of 32 hemiparalysis children patients after light craniocerebral trauma
Chinese Journal of Primary Medicine and Pharmacy 2011;18(13):1751-1752
Objective To analyze the mechanism of hemiparalysis children,cerebral vessels' physiological feature of children, pathological change and therapeutic efficacy after light craniocerebral trauma. Methods To analyze clinical manifestation,imageology data,therapy and therapeutic efficacy of 32 hemiparalysis children patients after light craniocerebral trauma. Results Mon-basal ganglia cerebrel infarction was discovered in all children,and cure rate of broadening blood vessel therapy was 84% in a week after trauma. Conclusion Blood vessel spasm and thrombosis happened after light craniocerebral trauma to artery of cerebral hemorrhage that erupt perpendicularly from arteria cerebri media and had incomplete tunica intima development. Nonage broadening blood vessel therapy could gain well curative effect.
5.Mechanisms and clinical applications of nitric oxide in neonatal diseases
Chinese Pediatric Emergency Medicine 2012;19(1):93-95
Nitric oxide (NO) is a vascular endothelium-derived relaxing factor.NO inhalation therapy is widely used in the field of neonatology.When NO acts as selective pulmonary vasodilation,it can reduce pulmonary arterial pressure and improve oxygenation.When NO serves as a major regulator of cerebral vasomotor factor,it may have physiological and pathological impact in cerebral ischemia-reperfusion injury.So NO has a wide range of applications in persistent pulmonary hypertension of the newborn,bronchopulmonary dysplasia,hypoxia ischemic encephalopathy.With the recently in-depth study of NO,its biological role has more and more clinical attention in the field of neonatology and has broad valid prospects.However,NO has some side effects which still have some controversial aspects of the application in premature,especially in very low birth weight children.The article focused on the mechanism and clinical applications of NO in the neonatal disease.
6.Complications and impact on the secretion of digestive juice of octreotide acetate prophylactic application of head of pancreas after pancreaticoduodenectomy
Clinical Medicine of China 2013;29(8):815-817
Objective To investigate the preventive application of octreotide acetate for the prevention of complications and serum pancreatic amylase secrection after pancreatoduodenectomy(PD).Methods Fiftysix cases who underwent PD in our hospital were randomized into the observational group (n =28) and the control group (n =28).The control group received routine preoperative treatment including fasting,gastrointestinal decompression,nutritional support,maintenance of water,electrolyte balance and the use of antibiotics,postoperative routine parenteral nutrition and antibiotic therapy.In addition to the conventional treatment,the observational group received prophylactic application of octreotide acetate by subcutaneous injection of 0.1 mg each time,3 times a day,and 7 days for a cycle of treatment.Blood biochemical index and postoperative complications in the two groups were monitored.Results The serum amylase levels in the observational group and the control group were (304.63 ±62.21) U/L and (445.52 ±64.52) U/L respectively at the tenth day after treatment.The two groups are significantly different in the serum amylase level (t =2.243,P < 0.05).The pancreatic juice,gastric juice and bile drainage of patients in the observational group and the control group were (46.83 ± 31.42) ml,(189.92 ± 59.64) ml,(178.94 ± 45.18) ml,and (69.84 ± 34.30)ml,(237.08 ±71.27) ml,(356.11 ±64.23) ml respectively.The observational group had significantly reduced digestive fluid drainage volume compared with the control group (t =3.219,2.276,4.618 respectively,P <0.05).Complications occurred in 3 patients of the observational group (including 1 case of pancreatic fistula,1 case of hemorrhage,and 1 case of gastric emptying delay),with an incidence of 10.71% (3/28).Complications occurred in 12 cases of the control group (including 3 cases of pancreatic fistula,2 cases of hemorrhage,3 cases of bile leakage,2 cases of delayed gastric emptying,2 cases of peritoneal infection),with an incidence of 42.86% (12/28).There was significant difference between two groups in the incidence of complications (x2 =4.293,P < 0.05).Conclusion Prophylactic application of somatostatin in PD restrains the secretion of digestive juice,and plays a preventive role for postoperative complications.The routine prophylactic application of octreotide in PD is necessary.
7.Study on the Stability of Impact Assay for Detection of Microorganism of Indoor Air
Journal of Environment and Health 2000;17(6):358-359
To explore the stability of impact assay for determination of microorganism in indoor air, the comparisons of continued sampling times of 2-minute and 4-minute for monitoring on microorganism of indoor air were carried out with JWL- Ⅱ B multifunctiom air microorganison monitor in 11 hotels, public places of entertainment, barbar shops and beauty shops. The results showed that, under a same environmental condition, there was no significant differences between the data obtained by 2-minute monitoring and 4-minute monitoring (t=1.854, P>0.05).It indicated that impact assay presented very good stability in detecting the microorganism of indoor air within certaindetecting duration.
9.Identification of psychological factors in refractory functional gastrointestinal disorders
Chinese Journal of Practical Internal Medicine 2000;0(12):-
Functional gastrointestinal diseases(FGIDs) mainly include functional dyspepsia (FD),irritable bowel syndrome (IBS),functional constipation (FC) and functional abdominal pain syndrome (FAPS).In gastroenterology outpatient,42%~61% FGIDs patients have psychological factors,mostly depression and anxiety.The personality of these patients are almost introvert.Negative life events can be an incentive to lead to depression and anxiety which can aggravate the functional gastrointestinal symptoms.Clinical manifestations include long-term abdominal discomfort,abdominal pain (some with no fixed position),abdominal distension,anorexia,change in bowel habits,retrosternal and upper abdominal burning pain or overlapping symptoms.Some have obvious emotional performance.Dyspepsia symptom score of FD patients with mental disorders are higher than those who have no emotional performance and the gastric emptying decrease greatly than the latter.FGIDs treated by systemic therapy but with no improvement in symptoms may have somatization,compulsion,interpersonal tension,depression,anxiety and other psychological disorders.So psychological evaluation should be carried out to make early recognition for refractory functional gastrointestinal disorders.
10.Experience of LI Ji-ren in treating chronic nephritis albuminuria
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(01):-
TCM has dominance and characteristics in treating chronic nephritis, such as protecting the function of kidney and defering the kidney crocking up. Professor LI Ji-ren, a famous herbalist and the gainer of the special allowance of the State Council, has worked on clinic for 60 years. He Accumulates abundant experiences in treating chronic nephritis. On clinic, Professor Li advocates integratation of syndrome differentiation and disease differentiation, attaching importance to protect the basic of body and flexibility of syndrome differentiation. In aspects of medication, he begins with treating spleen and kidney,at the same time, harmonizing the qi and blood, detaching the clear and dirtiness, protecting other organs. Danbai Zhuanyin Prescription, containing thirteen herbal medicines, has marked effect on chronic nephritis albuminutia.