2.Comparison of efficacy of remifentanil combined anesthesia and fentanyl or sufentanil combined anesthesia in patients undergoing cardiac surgery: a Meta-analysis
Zhaoduan LI ; Fen ZHOU ; Yumiao YAN ; Shuan DONG ; Jianbo YU
Chinese Journal of Anesthesiology 2012;32(7):860-862
Objective To compare the efficacy of rcmifentanil combined anesthesia and fentanyl or sufentanil combined anesthesia in patients undergoing cardiac surgery.Methods We searched the Coehrane library,PubMed,EMBASE,OVID and Chinese Biomedical Database for prospective randomized controlled trials involving the comparison of the efficacy of remifentanil combined anesthesia and fentanyl or sufentanil combined anesthesia in patients undergoing cardiac surgery.The quality of the studies was evaluated by the method recommended by Cochrane Collaboration.Evaluation indexes included the mechanical ventilation time after operation,duration of stay in hospital,and level of cardiac troponin,mortality,requirement for positive inotropic drugs and incidence of hyperalgesia and myocardial infarction during perioperative period.Meta-analysis was conducted using the RevMan 5.0 software.Results Sixteen prospective randomized controlled trials involving 1473 patients were included in our Meta-analysis.The patients were divided into 2 groups:fentanyl or sufentanil group ( n =644) and remifentanil group ( n =573).Compared with fentanyl or sufentanil group,the mechanical ventilation time after operation and duration of stay in hospital were significantly shortened,the level of cardiac troponin during the perioperative period was significantly decreased and the requirement for positive inotropic drugs during the perioperative period was significantly reduced ( P < 0.05),and no significant change was found in the incidence of hyperalgesia or mortality of myocardial infarction during the perioperative period in remifentanil group ( P > 0.05 ).Conclusion The efficacy of remifentanil combined anesthesia is better than that of fentanyl or sufentanil combined anesthesia in patients undergoing cardiac surgery.
3.Pseudoangiomatous variant of spindle cell lipoma: report of a case.
Bing-wei DONG ; Xiao-yan MA ; Hui-nü HE ; Fen-juan ZHANG
Chinese Journal of Pathology 2013;42(5):343-344
12E7 Antigen
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Antigens, CD
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metabolism
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Antigens, CD34
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metabolism
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Cell Adhesion Molecules
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metabolism
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Diagnosis, Differential
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Head and Neck Neoplasms
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metabolism
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pathology
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Hemangioma
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pathology
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Humans
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Lipoma
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metabolism
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pathology
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Liposarcoma, Myxoid
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pathology
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Male
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Middle Aged
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S100 Proteins
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metabolism
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Soft Tissue Neoplasms
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metabolism
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pathology
4.Expressions of hTERT, HIF-1alpha and CD105 in gliomas and their clinical significance.
Yan-fen WANG ; Dong-lin WANG ; Gong-sheng SHI ; Hua HUANG
Chinese Journal of Pathology 2006;35(11):681-682
Adolescent
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Adult
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Aged
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Antigens, CD
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biosynthesis
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Brain Neoplasms
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blood supply
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metabolism
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pathology
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Child
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Endoglin
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Female
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Glioma
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blood supply
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metabolism
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pathology
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Humans
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Hypoxia-Inducible Factor 1, alpha Subunit
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biosynthesis
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Immunohistochemistry
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Male
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Middle Aged
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Neovascularization, Pathologic
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metabolism
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pathology
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Receptors, Cell Surface
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biosynthesis
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Telomerase
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biosynthesis
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Young Adult
5.The differentiatial diagnostic value of 99Tcm-MIBI SPECT combined with localizable CT imaging in oxygen intervention for lung lesions
Chang-jiang, LIU ; Qing, ZHANG ; Xu, ZHANG ; Gui-fen, PANG ; Yan-yu, DONG
Chinese Journal of Nuclear Medicine 2010;30(4):232-236
Objective To investigate the differentiatial diagnostic value of 99Tcm-methoxyisobutylisonitrile ( MIBI ) SPECT combined with localizable CT in the evaluation of oxygen intervention for suspicious lung lesions,and to establish a cost-effective imaging modality in the detection of malignant lung lesions.Methods From September 2008 to March 2009,47 consecutive patients with suspicious malignant lung lesions underwent 99Tcm-MIBI SPECT/CT prospectively. Patients with suspicious pneumonia were treated with antibiotics for about 4 d before imaging. All patients were cannulized with a nostril tube for oxygen inhalation before 99Tc-MIBI injection. SPECT combined with localizable CT of the chest was performed at 10 min and 2 h after 99Tcm-MIBI injection. The uptake ratios of lesion to contralateral normal lung parenchyma(early uptake ratio:EUR and delayed uptake ratio:DUR) were compared using independent-samples ttest. In addition,the diagnostic efficiency of uptake ratios of lung lesions was analyzed with receiver operating characteristic (ROC) curve. Results Forty-seven patients ( primary lung cancers:32,metastatic tumors of the lung:4,benign lung diseases:11 ) had 51 lung lesions,including 39 malignant and 12 benign lung lesions. The sensitivity,specificity,accuracy,positive predictive value (PPV),and negative predictive value (NPV) were 94.9% (37/39),83.3% ( 10/12),92.2% (47/51),94.9% (37/39) and 83.3% ( 10/12),respectively. The EUR of malignant lesions was 2.95 ± 1.16,whereas of benign lesions was 1.43 ±0.33. The DUR of the malignant lesions was 3.19 ± 1.74,whereas of benign lesions was 1.60 ±0.32. Both EUR and DUR were significantly different between malignant and benign lung lesions,respectively (t= -4.44,-3.12,respectively,both P<0.01). The ROC curve showed that EUR value ≥1.625 provided the sensitivity of 97.4% (38/39) and specificity of 83.3% (10/12); DUR value ≥ 1.75provided the sensitivity of 94.9% (37/39) and specificity of 83.3% (10/12). Conclusion 99Tcm-MIBI SPECT combined with localizable CT imaging in oxygen intervention has a potential value in differentiating malignant from benign lung lesions.
6.Nursing care of patients with congenial arteriovenous fistula undergoing endovascular therapy
Chinese Journal of Modern Nursing 2010;16(10):1160-1162
Objective To summarize the perioperative nursing experience of the endovascular treatment for the congenial arteriovenous fistula.Methods The perioperative nursing experience including pre-operative evaluation and psychological care,postoperative prevention of complications and nursing following up of 30 cases of congenial arteriovenous fistula patients undergoing endovascular treatment were summarized.Results The endovascular treatment succeeded in 25 cases.Symptoms of those patients were improved after operation and no complications and death appeared.The rest five patients did not perform the endovascular treatment.During the period of six months following up,five recurrences were found but the symptoms were milder than preoperative situation.Conclusions The endovascular treatment is effective,microinvasive,safe and with fewer complications.
7.Perioperative nursing of the catheter-guided foam sclerosis therapy on cirsocele
Chinese Journal of Modern Nursing 2011;17(7):848-849
Objective To discuss perioperative nursing method of catheter-guided foam sclerosis therapy on cirsocele. Methods Twenty patients with cirsocele from April 2008 to April 2010 were treated by injecting one percent aethoxysklerol to the spermatic vein guided by the catheter. Psychological prepare for patients, perioperative guidance and observation were well done. Results All the twenty patients were injected successfully guided by the catheter. Varicose vein disappeared significantly through effective nursing.Conclusions The catheter-guided foam sclerosis therapy on cirsocele is a new domestic microtraumatic method.The medical staff should provide patients with effective cognition, psychological instruction and recovery guide,intensive care on the condition of patients to prevent adverse effects.
8.Design of traditional Chinese medicines with antihypertensive components based on medicinal property combination modes.
Su-Fen LIAO ; Su-Rong YAN ; Wei-Jia GUO ; Ji LUO ; Jing SUN ; Fang DONG ; Yun WANG ; Yan-Jiang QIAO
China Journal of Chinese Materia Medica 2014;39(13):2389-2391
Multi-component traditional Chinese medicines are an innovative research mode for traditional Chinese medicines. Currently, there are many design methods for developing multi-component traditional Chinese medicines, but their common feature is the lack of effective connection of the traditional Chinese medicine theory. In this paper, the authors discussed the multi-component traditional Chinese medicine design methods based on medicinal property combination modes, provided the combination methods with the characteristics of traditional Chinese medicine for the prescription combinations, and proved its feasibly with hypertension cases.
Animals
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Antihypertensive Agents
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administration & dosage
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chemistry
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Blood Pressure
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drug effects
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Drug Combinations
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Drug Therapy
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Drugs, Chinese Herbal
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administration & dosage
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chemistry
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Humans
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Hypertension
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drug therapy
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physiopathology
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Medicine, Chinese Traditional
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Rats
9.Multivariate and multilevel model analysis on factors that influencing the literacy of health among high school students in Guangdong province
Xiao-Hua YE ; Ya XU ; Shu-Dong ZHOU ; Yan-Hui GAO ; Yan-Fen LI
Chinese Journal of Epidemiology 2011;32(9):873-876
Objective To analyze the awareness on health among high school students and its influencing factors in Guangdong. Methods Multi-stage sampling and questionnairs "2009 health awareness survey of the Chinese citizens" developed by our Department of Health, were used. Data were analyzed by multivariate multilevel model under MLwinN 2.19 software. Results The mean scores on knowledge and ideas, behaviors and related skills among 1606 high school students of Guangdong province, were 69.08 ± 14.81,60.05 ± 16.85 and 74.99 ± 21.17 respectively. Three items on health showed that they all related to each other and relations between grades (0.972,0.715 and 0.855) were greater than the individuals (0.565,0.426 and 0.438). Conclusion Factors as students from outside the Pearl River Delta region or from the rural areas, being male, at general secondary schools, at grade one, with poor academic performance and more pocket money etc., had lower levels on those related information of health.
10.Massage manipulation of supplementing marrow and kneading tendon in treating 30 children with spastic cerebral palsy.
Yue WANG ; Wen-Lian ZHU ; Yan-Fen DONG
Chinese Journal of Integrated Traditional and Western Medicine 2008;28(4):363-365
OBJECTIVETo observe the therapeutic effect of massage with manipulation of supplementing marrow and kneading tendon (SMKT) on spastic cerebral palsy (CP).
METHODSA total of 60 children with CP were randomly assigned to the treatment group and the control group equally. All were treated with rehabilitation training, but massage with SMKT was carried out additionally for those in the treatment group, five times every week and 3 months as a therapeutic course. Clinical efficacy was assessed adopting the gross motor function measurement (GMFM-66) and the revised Ashworth scale (MAS) before and after treatment.
RESULTSAll children showed significant improvements in GMFM-66 after treatment. Compared with baseline, the improvement was statistically significant (P <0.01). Significant difference was also found between the 2 groups in MAS and in GMFM scores after treatment (P <0.05).
CONCLUSIONMassage with SMKT manipulation shows a better effect than rehabilitation training therapy alone in treating spastic CP.
Cerebral Palsy ; physiopathology ; therapy ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Male ; Massage ; Muscle, Skeletal ; physiopathology ; Tendons ; physiopathology