1.Clinical laboratory tests of venous thromboembolism in obstetrics and gynecology
Chinese Journal of Laboratory Medicine 2017;40(3):149-151
Venous thrombotic disease is a serious disease,which impact on health and life-threatening.Pulmonary embolism and deep-vein thrombosis are the two components of a single disease called venous thromboembolism in obstetrics and gynecology.but it can be difficult to diagnose because clinical symptoms and signs are non-specific or absent in early venous thrombus embolism (VTE).It has great value that how to use the most economic,simple,efficient method for screened high-risk groups,timely and accurate laboratory diagnosis of VTE.
2.The development of military acute stress scale
Chinese Journal of Behavioral Medicine and Brain Science 2012;21(7):658-661
ObjectiveTo develop the military acute stress scale and examine the reliability and validity of this scale.MethodsBased upon the previous acute stress researches and the rule of psychometrics,the military acute stress scale was compiled according to open-ended inventory survey.A total of 630 personnel were chosen by random cluster sampling,and tested with this scale,50 of them were tested by Chinese Military psychosomatic health Scale simultaneously,and 50 of them were retested after two week.The reliability and validity were examined by exploratory factor analysis,confirmatory factor analysis and correlation analysis.ResultsThe military acute stress scale was comprised of 9 factors and one lie sub-scale ; Main fit indexes of model were the following CMIN =1219.476,DF =593,P =0.000,CMIN/DF =2.056,IFI =0.927,TLI =0.902,CFI =0.924,RMSEA =0.059; The conrelation coefficients between subscales and subscales were 0.284-0.572.The correlation coefficients between subscales and total scale were 0.700 ~ 0.846 (P < 0.05 or 0.01 ) ; The correlation coefficients was significant between this scale and Chinese military psychosomatic health scale.The correlation coefficients were 0.338-0.962 (P < 0.01 ).The test-retest correlation coefficients of total scale and subscales were 0.379-0.909 (P < 0.01 ).The Cronbaeh's α coefficients were 0.606-0.926 ; and the split-half correlation coefficients were 0.466-0.855.ConclusionThe military acute stress scale has acceptable psychometrics properties on reliability and validity.
3.Surface Enhanced Raman Scattering Analysis on Safflower Injections
China Pharmacist 2015;(5):759-760,761
Objective:To study the surface enhanced Raman scattering ( SERS) of safflower and identify safflower injections by SERS quickly and effectively. Methods:Through comparative analysis of the Raman spectroscopy of safflower injections and the corre-sponding control herbs, the rapid identification of safflower injections was realized. Results:The results showed that several character-istic peaks of safflower were enhanced obviously in SERS, which could be used to identify safflower injections. Conclusion:The meth-od is reliable, rapid, accurate and specific, which can be applied as a method to identify safflower and its injections.
4.Effects of electro-acupuncture combined with hyperbaric oxygen on cognitive ability and plasma homocysteine in patients with dementia after cerebral infarction
Chinese Journal of Primary Medicine and Pharmacy 2013;20(21):3223-3225
Objective To explore the influence of electro-acupuncture combined with hyperbaric oxygen on cognitive ability and plasma homocysteine(Hcy) in patients with dementia after cerebral infarction.Methods 68 patients with dementia after cerebral infarction were randomly divided into the control group (34 cases) and the observation group(34 cases).The patients in the control group were treated through conventional treatment,and the patients in the observation group were treated through electric stimulation plus hyperbaric oxygen,one time every day,15 times was a course of treatment.The intelligence was evaluated and the level of Hcy was detected after treatment.Results Before treatment,the MMSE score and the plasma Hcy level of the observation group was (19.01 ±6.92) points,(26.84 ± 9.06) μmol/L,respectively,those of the control group was (18.76 ± 6.71) points,(26.14 ±8.79) μmol/L,respectively.After treatment,the MMSE score and the plasma Hcy level of the observation group was (25.77 ± 8.21) points,(15.15 ± 5.24) μmol/L,respectively,those of the control group was (20.18 ± 7.52) points,(21.32 ± 6.53) μmol/L,respectively.After treatment,the MMSE score of the observation group was significantly increased (t =3.6710,P < 0.05),and there was no significant change in the control group (t =0.5472,P > 0.05).The plasma Hcy level was significantly reduced after treatment in both two groups (t =2.0345,P < 0.01,t =2.5667,P <0.05),and that in the observation group was siginificantly lower than the control group (t =4.2970,P < 0.05).Conclusion Electric stimulation combined with hyperbaric oxygen can improve cognitive ability and decrease plasma Hcy level in patients with dementia after cerebral infarction.
5.Hyaluronate acid and oxidized regenerated cellulose prevent adhesion reformation after adhesiolysis in rat
Chongqing Medicine 2017;46(5):593-595
Objective To evaluate the effect of pelvic adhesiolysis to prevent readhesion in the second look operation.Methods 30 rats underwent laparotomy incision of uterus to create intraperitoneal adhesions models.The animals were randomly divided into three groups:the first group:isotonic Na chloride (n =10);the second group:medical Sodium Hyaluronate (n =10),the third group:Oxidized regenerated cellulose.After 2-week recovery period,the animals were operated andintraperitoneal adhesions were assessed,then,all adhesions were released and set isotonic Na chloride,medical Sodium Hyaluronate and Oxidized regenerated cellulose.Again,After 2-week recovery period,the animals were killed and the intraperitoneal adhesions were assessed.Results After the first operation the three groups had significant difference (F=7.114,P<0.05),After the second operation the three groups had no significant difference(F=0.280,P>0.05).Conclusion Medical sodium hyaluronate and oxidized regenerated cellulose are effective methods to prevent postoperative adhesions.However,they are ineffective to prevent readhesion after adhesiolysis.
6.Study on the dose-effect relationship of sufentanil with dexmedetomidine after hip arthroplasty in PCIA
Journal of Chinese Physician 2016;18(2):236-239
Objective To investigate the dose-effect relationship of sufentanil combined with dexmedetomidine which used in clinical effectiveness and safety of intravenous analgesia after hip arthroplasty.Methods Sixty patients (after hip arthroplasty) were randomly divided into three groups:group A (sufentanil 0.5 μg/kg),group B (sufentanil 0.75 μg/kg),and group C (sufentanil 1 μg/kg).Each group was combined with dexmedetomidine 1.5 μg/kg in patient controlled analgesia (PCA) pump.Mean arterial pressure (MAP),heart rate (HR),SpO2,numerical rating scale (NRS) scores,and Ramsay sedation scores were recorded at T1 (4 h after operation),T2 (8 h after operation),T3 (24 h after operation),and T4(48 h after operation).Harris hip scores were recorded at T0(preoperative),T3,and T4.The total number of pushing patient controlled intravenous analgesia (PCIA),dezocine dosage,and the occurrence of adverse events in each group situation were recorded.Results There were no significant differences in MAP,HR,and SpO2 among groups.Compared to group A,NRS scores of groups B and C were lower during the analgesia (P <0.01).Compared to group A,Ramsay sedation scores of groups B and C were higher at T1,and T2 (P < 0.01).Compared to group A,Harris hip scores of groups B and C were higher at T3,and T4 (P < 0.01).Compared to group C,adverse reactions of groups A and B were less during the analgesia (P < 0.01).Compared to group A,the total number of press PCIA and dezocine amount were decreased in groups B and C (P < 0.01).Conclusions The 0.75 μg/kg sufentanil combined with 1.5 μg/kg right beauty holds the minimum for intravenous analgesia effect after hip arthroplasty and calm exactly satisfied,less adverse reaction,for PCIA ideal drug formula.
7.Cost-effectiveness Analysis of Three Kinds of Statins for the Treatment of Hyperlipoidemia
China Pharmacy 2001;0(08):-
AIM:To evaluate the economic effectiveness in the treatment of hyperlipoidemia with three kinds of statinsMET_HODS:Using pharmacoeconomical cost-effectiveness analysis,simvastatin,fluvastatin and pravastatin in the treatment of 215 cases of hyperlipoidemia were comparedRESULTS:Fluvastatin was the best kind of statins in lasting treatment for hyperlipoidemiaCONCLUSION:The results show that pharmacoeconomics plays an important role in guiding rational drug use and increasing economic effectiveness
8.Pharmacodynamics of Xuanguizhitong Drop Pill in the Treatment of Pain Caused by Qi-blood Stasis
China Pharmacy 1991;0(06):-
OBJECTIVE:To study the pharmacodynamics of Xuanguizhitong drop pill in the treatment of pain caused by Qi-blood Stasis. METHODS: Xuanguizhitong drop pill were prepared into 3 different doses (0.25,0.5, and 1 g?kg-1) with new distilled water. The effects of Xuanguizhitong drop pill at different dose in promoting blood flow, analgesia, anti-inflammatory effect, the ability of anoxia-tolerance at ordinary pressure, and improving the hemorheology indexes in blood stasis model animals were compared. RESULTS: Xuanguizhitong drop pill were remarkable in analgesic, anti-inflammatory and anticoagulant effects and anoxia-tolerance ability at ordinary pressure.The hyperviscosity, thickness, coagulation and accumulation of blood caused by "cold accumulation" in the blood stasis syndrome model rabbits were also improved significantly by Xuanguizhitong drop pill.CONCLUSION:Xuanguizhitong drop pill has remarkable analgesic effect and can promote blood flow to a certain extent.
9.Efficacy of Pulmonary Surfactan in the Treatment of Infants with Acute Respiratory Distress Syndrome
China Pharmacy 2005;0(17):-
OBJECTIVE:To evaluate the efficacy of pulmonary surfactan (PS) in the treatment of acute respiratory distress syndrome (ARDS) in infants after undergoing cardio-pulmonary bypass. METHODS: Twenty ADRS infants were randomly assigned to receive routine therapy alone (control group) or routine therapy in combination with PS (trial group). The clinical efficacy in two groups was monitored. RESULTS: In the trial group compared with the control group, the mortality rate was significantly lower(P
10.To Steer the Rudder of Fairness:On Government Functions in the Property Rights System Reform in Rural Healthcare Centers
Chinese Medical Ethics 1994;0(06):-
Community participation in the rural healthcare service is still necessary under existing Chinese social conditions to achieve the goal of providing general rural public with safe,effective,convenient and inexpensive medical and healthcare services,as is declared in the 17th national people's committee report.The property rights system reform in rural healthcare centers is a reflection of community participation,and related problems in its participation process should be handled by steering the rudder of fairness when the Government applies its functions.The ultimate goal of rural healthcare property rights reform is to achieve the healthcare fairness for every rural individual,and thus right of each participator and fairness in the reform should be ensured.