Objective To observe absorption of exogenous nerve growth factor(NGF) between normal newborn rats and newborn rats with hypoxidosis.Methods Thirty-two healthy newborn rats(7 days of age) were divided into experiment group and normal group.Experiment rats were made into hypoxic-ischemic brain damage(HIBD) model.NGF labeled with()~(125)I or()~(125)I was injected into the rats abdominant.All of the rats were killed and brain was removed after 30 minutes.The brain was dissected into basal forebrain,forehead cortex,hippocampus,thalamus,cerebellum,smellorb,pituitary tissue samples were assayed for radioactivity in a two-channel gamma counter.Results Absorptions of two groups(()~(125)I-NGF) were significantly higher than those of()~(125)I in basal forebrain,cortex,hippocampus,cerebellum.Absorptions of hypoxic group were significantly higher than those of control group in cortex,hippocampus,cerebellum.Conclusions NGF can penertrate blood brain barrier of newborn rats into brain regions by means of peripheral administration.Early application of NGF for treating hypoxic-ischemic encephalopathy(HIE) is feasible.

The accelerating pace of exchanges and cooperation in medical field between China and foreign countries demands a large number of medical papers, medical-related materials to be ac-curately translated into multiple languages , especially between English and Chinese . Oriented at English majors (medicine directed), based on eco-translatory approach and student-centered teaching method by creating simulations of the medical English ecological translation environment, this paper provided a better and effective practice-based teaching idea, which can promote students' medical English translation competence and strategies, even cultural consciousness and pragmatic ability in a comprehensive manner.

Microglia(MG)is recognized as the main immune effector in central nervous system injury and disease.MG can regulate the tumorigenesis and development of brain metastases tumor(BMT)by different ways.Studing the roles and mechanisms of MG in BMT will provide new insights into the prevention and treatment of BMT.

Objective To evaluate the teaching quality of AIDS and drug abuse and to provide evidences for teaching improvement.Methods Quantitative research and qualitative research was combined.Questionnaire including evaluation of curriculum,teachers and teaching quality was conducted among 273 students majored in anesthesiology and clinical medicine (2006 grade) as well as in forensic medicine,laboratory and stomatology (2008 grade) in quantitative research.Observation and indepth interview were used in qualitative research to observe the teaching process and receive students'feedback.Information about students' evaluation criterions and attitude toward teachers were collected by qualitative research.Chi-square test and descriptive statistic were used with SPSS 13.0.Results 90.8％ students thought this lesson was necessary and important and the contents were accepted by them.24.2％ students expected increasing study hours and having practice classes.Evaluation of course time,contents and importance were different by students of different majors.Average scores of students' evaluation on teachers' quality,teaching contents and teaching methods were 25.2,22.4,11.0,respectively.Three aspects of teaching methods got the lowest scores:vivid (2.71 points out of 3.0 points),interaction (2.71 points out of 3.0 points) and flexibility (2.72 out of 3.0 points).Interview results demonstrated that students have diversified demand for teaching methods and expect to increase practice lessons and multimedia teaching as well as to effective communicate between teaching and learning.Conclusions Course of AIDS and drug abuse is accepted by students.As a whole,students are basically satisfied with teachers,however,teachers and related sectors should pay more attention to teaching method improvement and teaching skill enhancement.

Recently,paclitaxel has been used as a new agent on patients with advanced esophageal cancer,and several studies have demonstrated that paclitaxel and paclitaxel-based regimens have significant activity in patients with advanced esophageal cancer and showed highly response rates than the combination of 5-fluorouracil (5-Fu) and cisplatin.However,there have been some problems which need to be solved such as drug-resistance,side effect,and so forth.The new medicament form of paclitaxel can not only depress poison without anti-allergy but also raise medicament curative effect as well as the pharmacal concentration.Although most of the research on the new medicament form of paclitaxel are still limited in the stage of laboratory,it has possessed potential advance in the treatment of advanced esophageal cancer.

Objective To study the the current situation of sexual for college students in luzhou area and to provide basis for their sexual health education .Methods 2 226 college students from four colleges in luzhou area were investigated by stratified clus-ter sampling method ,SPSS11 .5 software was used to analysis the results .Results 59 .62% of the students′knowledge was mainly from the media ,the test for sexual knowledge of college students′was satisfactory ;58 .94% of college students would like to com-municate and communication about sex and love ,84 .61% of the students thought that college students should have correct love and chastity view ,82 .95% of the students thought that should make efforts to prevent venereal disease and AIDS ,55 .27% of the students were firmly opposed to marriy during school study ;75 .15% of the students were firmly opposed to premarital sexual be-havior ,44 .44% of the students minded that lover once had sex ,36 .56% of the students broken up immediately when found that loveer had sex before .Conclusion The college students′sexual maturity in advance but knowledge of sex education relative lag , making them for many sexual problems and phenomena ,so scientific and systematic sexual health education should be strengthen in students .

Objective To evaluate the accuracy of the soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) and lipopolysaccharide binding protein (LBP) as diagnostic indices for neonatal serious bacterial infections (SBI). Methods A total of 171 newborns were enrolled in the study, and were classiifed into SBI group (including early-onset and late-onset), non-SBI group according to clinical manifestations, laboratory examinations and the time of disease onset. Serum sTREM-1, LBP and C-reactive protein (CRP) levels were measured. Receiver operator characteristic curve (ROC) was drawn, and the area under curve (AUC) was calculated. Each index was evaluated for the diagnostic value of neonatal SBI. Results The sTREM-1 and LBP levels were signiifcantly higher in SBI group than those in non-SBI group (P=0.000). The AUC of ROC for sTREM-1, LBP and CRP in early-onset SBI was 0.888, 0.839 and 0.706, respectively. The AUC of ROC for sTREM-1, LBP and CRP in late-onset SBI was 0.860, 0.865 and 0.705, respectively. Conclusions Both sTREM-1 and LBP are useful for the diag-nosis of neonatal SBI.

Objective To compare the effect of different dose human immunoglobulin for intravenous injec-tion( IVIG) in the treatment of Kawasaki disease ( KD) .Methods According to different time ,55 children with KD were divided into two groups.26 patients between January 2002 and February 2006 were selected as group A,while 29 patients between October 2006 and June 2013 were selected as group B .Patients in group A were given IVIG 0.4 g· kg-1 · d-1 ×5d,while group B was given IVIG 2 g· kg-1 · d-1 ×1d.Then,the time of fever-reducing and CAL of the two groups were compared .Results The time of fever-reducing in group A was (38 ±4) h,that in group B was (34 ±3)h,there was significant difference between the two groups (t=4.15,P<0.05).The incidence rate of CAL in group A was 6.9%,which was higher than 6.1%in B group,but the difference was not statistically signifi-cant(χ2 =0.253,P>0.05).Conclusion The treatment of KD with IVIG 2 g· kg-1 · d-1 ×1d is more superior than IVIG 0.4 g· kg-1 · d-1 ×5d.

Helical tomotherapy is the radiation treatment device that combined CT imaging with a linear accelerator, and capable of implementing 360-degree intensity modulated radiation therapy (IMRT), MVCT image guidance, adaptive therapy, stereotactic radio-surgery (SRS) and stereotactic body radiation treatment (SBRT) etc. A very broad spectrum of tumor can be treated by helical tomotherapy.

Objective To investigate and improve the methods of nasal feeding to reduce the occurrence of complication such as diarrhea and vomiting.Methods We separated 140 patients with heavy craniocerebral injury into the control group (50 patients) and the experimental group (90 patients) according to different nasal feeding methods. For the control group traditional method was used. For the experimental group infusion pump was used to control infusion rate. The incidence of complication was compared between two groups. And within experimental group, the same nutrient solutions in respect of type and volume were infused during 10 hours, 16 hours, and 18 hours respectively. The relationship between infusion rate and the occurrence of complication was observed, analyzed and compared to seek for the most suitable enteral nutrition route which incurred the least complication.Results The incidence of diarrhea and vomiting in the experimental group was lower than that of the control group. And there were no significant differences in the occurrence of complication by using infusion pump at three different infusion rates within the experimental group. Conclusions The application of infusion pump in nasal feeding can reduce the incidence of complication and infusing nutrient solution at a slow rate was not necessary.