1.CT findings of desmoplastic small round cell tumor occurred in abdomen and pelvis
Chinese Journal of Radiology 2001;0(07):-
Objective To investigate the CT features of desmoplastic small round cell tumor (DSRCT)occurred in abdomen and pelvis.Methods The CT images of 4 patients with pathologically proven DSRCT occurred in abdomen and pelvis were retrospectively analyzed.Results The CT features common to the 4 DSRCT in abdomen and pelvis were as follows:the lobulated soft-tissue masses were very large;the masses often involved omental and serosal surfaces of abdomen and pelvis organ and had close relationship to the surrounding organs;the originating site of the tumors were not apparent;intratumoral hemorrhage or necrosis were often present;and contrast-enhanced CT scan showed mild to medium heterogeneous enhancement.Conclusion The CT features of DSRCT in abdomen and pelvis are rather specific and can provide helpful information to the clinical diagnosis.
2.Diagnostic Value of HRCT With Ankylosing Spondylitis in Sacroiliac Joint
Ping YANG ; Jukun CHEN ; Jianqi YAN
Journal of Practical Radiology 2000;16(12):715-717
Objective:To evaluate the effect of HRCT in diagnosis of the sacroiliac joint of ankylosing spondylitis(AS).Methods:HRCT scanning of sacroiliac joints were performed in 86 adult patients with AS.CT findings were reviewed.Rank test was used for statistical analysis of the grade of sacroiliac joint changes in two groups based on course of disease and the sex of patients.Results:The CT findings of the sacroiliac joint changes in AS included erosion,arthrosclerosis,change of joint space,arthrokleisis,gas and soft tissue in articular cavity.Pathologic changes were more obvious with the course of disease prolonged (P0.01).In the group during the same course,pathologic changes were more marked in female patients than those in male ones(P0.01).Conclusion:HRCT can show tiny structures of sacroitiac joint clearly.This is beneficial to recognize different patologic changes and make correct diagnosis.
3.Subjective visual experience during cataract surgery:A survey of patients and ophthalmologists
Ye, YANG ; Ping, WANG ; Hong, YAN
Chinese Journal of Experimental Ophthalmology 2013;(4):390-393
Background Patients' experience during phacoemulsification cataract surgery is an important determinant of patient's satisfaction with surgery effectiveness.Local anaesthesia could be associated with different intraoperative visual awareness because of retention of optic nerve function.Relieving the anxiety of patients arose from intraoperative visual awareness is of important clinical significance.Objective This study was to discuss the necessity of preoperative conversation and psychological counseling and to improve the quality of surgery and the satisfaction of patients.Methods One hundred and fifty-three patients who had undergone sequential phacoemulsification and intraocular lens (IOL) implantation in the same operation under local anaesthesia from October,2010 to December,2010 in Tangdu Hospital and Xi'an First People's Hospital,received a standardized questionnaire designed based on similar questionnaires from abroad and surveyed regarding their intraoperative visual experience,including light perception,their detection of color,photopsia,and their detection of the movement of the surgeon,instrument,and changes in light intensity during cataract surgery.In another survey,seventy ophthalmologists in the Xi'an area with ≥ 10 years (33) and < 10 years of experience (37) participated in a questionnaire about their recognition and response to these visual experiences,designed based on the 2010 Chinese Doctors General Questionnaire.Results During the phacoemulsification and IOL implantation,27 patients (17.6%) lost light perception,98 patients (64.1%) had light perception,28 patients (18.3%) detected more than one color,25 patients (16.3%) had photopsia,49 patients (45.1%) sensed the movement of the surgeon,26 patients (17.0%) was able to see surgical instruments,11 patients (7.2%) saw the surgeon's fingers,4 patients (2.6%) saw the surgeons,65 patients (42.5%) detected changes in light intensity and 12 patients (7.8%) saw the IOL loop and others.21.4% of the 70ophthalmologists believed these patients might have lost light perception;while 78.3% thought these patients retained light perception.Under local anaesthesia,93.9% of the more experienced surgeons and 75.6% of the junior surgeons deemed that good preoperative counseling was helpful for the patients,but only 45.5% of the more experienced surgeons and 24.3% of the junior surgeons counseled patients regarding intraoperative visual experience.Conclusions Most patients will experience a variety of visual sensations during phacoemulsification and IOL implantation under local anaesthesia.Many ophthalmologists are aware of these conditions.Most of the ophthalmologists believe that patients suffer from fear from these intraoperative visual experiences and claim that preoperative counseling to patients can relieve that fear,but less of them communicate these possible experiences to patients.This study offers some discussions about preoperative counseling.
4.Relationships between Low Birth Weight and Insulin Resistance and Adult Cardiovascular Disease
zi-yan, ZHAO ; ping-yang, CHEN
Journal of Applied Clinical Pediatrics 2004;0(08):-
The nutritional status in early life have been gradually recognized that it can change the status of development and metabolism of adults.Epidemiological evidence and animal model study have found that low birth weight is the risk factors of adult metabolic syndrome and cardiovascular disease.Insulin resistance is a common pathophysiological basis.Renin-angiotensin system and insulin signaling systems interact to promote the development of insulin resistance.
5.Advances in the Isolation Methods of Fungal Polyketide Synthase Genes
Shao-Hua YAN ; Liang GUO ; Yan-Ping LI ; Yang XU ;
China Biotechnology 2006;0(07):-
Fungal polyketide synthases are responsible for the biosynthesis of secondary metabolites such as pigments, mycotoxins, and they are very important in pharmacology , food science and agriculture. The recent advances in the methods for the isolation and manipulation of multiple classes of polyketide synthase genes from fungi were introduced. It is useful for discovery of novel fungal polyketide synthase gene clusters. These methods can also be useful for revealing the genetic potential of fungi to produce multiple types of bioactive polyketide.
6.Expression of heparanase in ovarian cancer and its clinical significance
Jing HAN ; Ying YANG ; Ping YAN ; Yan LIAN
Journal of Third Military Medical University 2003;0(20):-
Objective To examine the relationship of heparanase expression and age, clinicopathological features and prognosis of ovarian cancer patients. Methods Forty-one ovarian cancer specimens, from the patients admitted to the 3 hospitals of our university during the period of Jan 2003 to Nov 2005, were of serous carcinoma (22 cases) and mucous carcinoma (10 cases) and other types (9 cases), of which 16 were well and moderately differentiated and 25 poorly differentiated. Ten specimens of normal ovarian tissues were taken as normal controls. The heparanase expression was detected in all specimens and its relationship with histologic type, differentiation, FIGO stage and prognosis of the ovarian cancer was analyzed. Results The positive rate of heparanase expression was 80.48% in ovarian cancer tissues and 10.00% in normal ovarian tissues (P
7.Clinicopathological and molecular genetic characteristics of childhood diffuse large B cell lymphoma.
Hui HUANG ; Wen-ping YANG ; Hong-yan XU
Chinese Journal of Oncology 2012;34(3):209-211
Adolescent
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Antigens, CD20
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metabolism
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Antineoplastic Combined Chemotherapy Protocols
;
therapeutic use
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Burkitt Lymphoma
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drug therapy
;
metabolism
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pathology
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surgery
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Child
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Child, Preschool
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Cyclophosphamide
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therapeutic use
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DNA-Binding Proteins
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metabolism
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Doxorubicin
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therapeutic use
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Female
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Follow-Up Studies
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Genes, myc
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Humans
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Hyaluronan Receptors
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metabolism
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Ki-67 Antigen
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metabolism
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Lymphoma, Large B-Cell, Diffuse
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drug therapy
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genetics
;
metabolism
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pathology
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surgery
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Male
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Neoplasm Staging
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Neprilysin
;
metabolism
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Peritoneal Neoplasms
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drug therapy
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genetics
;
metabolism
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pathology
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surgery
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Prednisone
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therapeutic use
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Proto-Oncogene Proteins c-bcl-2
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metabolism
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Proto-Oncogene Proteins c-bcl-6
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Stomach Neoplasms
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drug therapy
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genetics
;
metabolism
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pathology
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surgery
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Translocation, Genetic
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Vincristine
;
therapeutic use
9.The clinical significance of ADAMT13 antigen change in thrombotic thrombocytopenic purpura patients by plasma exchange treatment.
Peng YANG ; Yan-ping LI ; Hui-qin WEN
Chinese Journal of Hematology 2012;33(10):879-880
ADAM Proteins
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blood
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immunology
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ADAMTS13 Protein
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Adult
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Female
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Humans
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Male
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Middle Aged
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Plasma Exchange
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Purpura, Thrombotic Thrombocytopenic
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blood
;
pathology
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therapy